| | | Sym | Name | Last | Chg | Chg% | Volume | | 1 | SHPG | Shire Plc ADS, Each Representing Three Ordinary Shares (MM) | 177.18 | -7.64 | -4.13% | 1,665,914.00 |
| 2 | CVCO | Cavco Industries, Inc. (MM) | 110.95 | -6.15 | -5.25% | 52,091.00 |
| 3 | MELI | Mercadolibre, Inc. (MM) | 286.95 | -5.47 | -1.87% | 488,282.00 |
| 4 | UHAL | Amerco (MM) | 348.29 | -5.11 | -1.45% | 258,264.00 |
| 5 | SPLK | Splunk Inc. (MM) | 62.41 | -4.68 | -6.98% | 10,078,893.00 |
| 6 | NRCIB | National Research Corp. (MM) | 44.71 | -4.58 | -9.29% | 5,204.00 |
| 7 | TSRO | Tesaro, Inc. (MM) | 149.11 | -4.08 | -2.66% | 675,370.00 |
| 8 | INCY | Incyte Corp. (MM) | 134.38 | -4.03 | -2.91% | 2,366,454.00 |
| 9 | ALNY | Alnylam Pharmaceuticals, Inc. (MM) | 65.80 | -3.70 | -5.32% | 1,356,852.00 |
| 10 | EQIX | Equinix, Inc. (MM) | 441.22 | -3.75 | -0.84% | 296,838.00 |
| 11 | LGND | Ligand Pharmaceuticals Incorporated (MM) | 110.19 | -3.31 | -2.92% | 217,861.00 |
| 12 | ICPT | Intercept Pharmaceuticals, Inc. (MM) | 112.15 | -3.11 | -2.70% | 254,591.00 |
| 13 | PRTA | Prothena Corp. Plc - Ordinary Shares (MM) | 51.88 | -2.97 | -5.41% | 255,687.00 |
| 14 | CLVS | Clovis Oncology, Inc. (MM) | 52.17 | -2.87 | -5.21% | 1,110,688.00 |
| 15 | PATK | Patrick Industries, Inc. (MM) | 64.95 | -2.70 | -3.99% | 132,159.00 |
| 16 | RARE | Ultragenyx Pharmaceutical Inc. (MM) | 55.91 | -2.61 | -4.46% | 304,845.00 |
| 17 | ONCE | Spark Therapeutics, Inc. (MM) | 52.99 | -2.63 | -4.73% | 244,070.00 |
| 18 | SIVB | Svb Financial Grp. (MM) | 176.50 | -2.51 | -1.40% | 548,298.00 |
| 19 | NBIX | Neurocrine Biosciences, Inc. (MM) | 46.22 | -2.43 | -4.99% | 1,626,169.00 |
| 20 | DJCO | Daily Journal Corp. (S.C.) (MM) | 211.40 | -0.93 | -0.44% | 1,806.00 |
| 21 | BWLD | Buffalo Wild Wings, Inc. (MM) | 151.00 | -2.25 | -1.47% | 398,791.00 |
| 22 | WINA | Winmark Corp. (MM) | 122.50 | -1.85 | -1.49% | 3,125.00 |
| 23 | JUNO | Juno Therapeutics, Inc. (MM) | 23.30 | -2.22 | -8.70% | 2,610,259.00 |
| 24 | BIIB | Biogen Inc. (MM) | 250.80 | -2.17 | -0.86% | 833,069.00 |
| 25 | SAGE | Sage Therapeutics, Inc. (MM) | 66.05 | -2.11 | -3.09% | 283,701.00 |
| 26 | GWPH | GW Pharmaceuticals Plc ADS (MM) | 106.13 | -1.89 | -1.75% | 219,092.00 |
| 27 | NDRM | Neuroderm Ltd. - Ordinary Shares (MM) | 21.30 | -1.95 | -8.39% | 243,839.00 |
| 28 | BPMC | Blueprint Medicines Corp. (MM) | 36.43 | -1.94 | -5.06% | 259,461.00 |
| 29 | KITE | Kite Pharma, Inc. (MM) | 73.11 | -1.80 | -2.40% | 1,183,307.00 |
| 30 | LAMR | Lamar Advertising Company (MM) | 68.91 | -1.73 | -2.45% | 392,682.00 |
| 31 | EA | Electronic Arts Inc. (MM) | 112.13 | -1.70 | -1.49% | 2,212,544.00 |
| 32 | OVBC | Ohio Valley Banc Corp. (MM) | 35.35 | -1.65 | -4.46% | 17,136.00 |
| 33 | VALU | Value Line, Inc. (MM) | 17.86 | -1.14 | -6.00% | 1,702.00 |
| 34 | BIDU | Baidu ADS, Each Representing One Tenth Class A Ordinary Share (MM) | 190.39 | -1.56 | -0.81% | 1,567,723.00 |
| 35 | JNCE | Jounce Therapeutics, Inc. (MM) | 21.17 | -1.50 | -6.62% | 92,750.00 |
| 36 | TTWO | Take-Two Interactive Software, Inc. (MM) | 77.07 | -1.46 | -1.86% | 2,311,891.00 |
| 37 | BWFG | Bankwell Financial Grp., Inc. (MM) | 31.81 | -1.50 | -4.50% | 11,548.00 |
| 38 | ANIP | Ani Pharmaceuticals, Inc. (MM) | 45.97 | -1.43 | -3.02% | 163,085.00 |
| 39 | ARGX | Argenx SE ADS (MM) | 20.15 | -1.26 | -5.89% | 93,443.00 |
| 40 | AVXS | Avexis, Inc. (MM) | 75.20 | -1.49 | -1.94% | 259,803.00 |
| 41 | JJSF | J & J Snack Foods Corp. (MM) | 131.39 | -1.35 | -1.02% | 72,825.00 |
| 42 | GBT | Global Blood Therapeutics, Inc. (MM) | 27.75 | -1.35 | -4.64% | 557,097.00 |
| 43 | FCNCA | First Citizens Bancshares, Inc. (MM) | 334.81 | -1.03 | -0.31% | 14,398.00 |
| 44 | FMI | Foundation Medicine, Inc. (MM) | 38.10 | -1.35 | -3.42% | 258,680.00 |
| 45 | KNSL | Kinsale Capital Grp., Inc. (MM) | 35.84 | -1.34 | -3.60% | 276,688.00 |
| 46 | WINS | Wins Finance Holdings Inc. - Ordinary Shares (Cayman Islands) (MM) | 26.75 | -0.65 | -2.37% | 772.00 |
| 47 | ALBO | Albireo Pharma, Inc. (MM) | 17.93 | -1.21 | -6.32% | 38,042.00 |
| 48 | MKTX | Marketaxess Holdings, Inc. (MM) | 194.17 | -1.39 | -0.71% | 192,368.00 |
| 49 | RDUS | Radius Health, Inc. (MM) | 34.93 | -1.27 | -3.51% | 1,348,866.00 |
| 50 | RRGB | Red Robin Gourmet Burgers, Inc. (MM) | 70.75 | -1.25 | -1.74% | 420,959.00 |
| 51 | RETA | Reata Pharmaceuticals, Inc. (MM) | 27.00 | -1.17 | -4.15% | 102,187.00 |
| 52 | FANG | Diamondback Energy - Commmon Stock (MM) | 98.41 | -1.22 | -1.22% | 1,363,398.00 |
| 53 | CACC | Credit Acceptance Corp. (MM) | 217.90 | -1.09 | -0.50% | 112,534.00 |
| 54 | GLPG | Galapagos NV ADS (MM) | 82.79 | -1.21 | -1.44% | 155,698.00 |
| 55 | PTLA | Portola Pharmaceuticals, Inc. (MM) | 36.72 | -1.21 | -3.19% | 563,723.00 |
| 56 | POPE | Pope Resources - Limited Partnership (MM) | 72.95 | -1.19 | -1.61% | 498.00 |
| 57 | SCVL | Shoe Carnival, Inc. (MM) | 19.52 | -1.18 | -5.70% | 341,131.00 |
| 58 | XLRN | Acceleron Pharma Inc. (MM) | 25.25 | -1.20 | -4.54% | 208,988.00 |
| 59 | PI | Impinj, Inc. (MM) | 44.83 | -1.18 | -2.56% | 449,890.00 |
| 60 | CBRL | Cracker Barrel Old Country Store, Inc. (MM) | 165.06 | -1.15 | -0.69% | 201,606.00 |
| 61 | AIMT | Aimmune Therapeutics, Inc. (MM) | 17.15 | -1.11 | -6.08% | 289,501.00 |
| 62 | OFLX | Omega Flex, Inc. (MM) | 60.40 | -0.30 | -0.49% | 12,054.00 |
| 63 | FSLR | First Solar, Inc. (MM) | 36.84 | -1.10 | -2.90% | 3,970,867.00 |
| 64 | CNBKA | Century Bancorp, Inc. (MM) | 59.95 | -1.10 | -1.80% | 4,340.00 |
| 65 | BLUE | Bluebird Bio, Inc. (MM) | 78.70 | -1.10 | -1.38% | 583,501.00 |
| 66 | SRCLP | Stericycle - Depository Receipt (MM) | 71.34 | -0.91 | -1.26% | 15,614.00 |
| 67 | INSM | Insmed, Inc. (MM) | 16.07 | -1.07 | -6.24% | 523,677.00 |
| 68 | NTES | Netease ADS, Each Representing 25 Ordinary Shares (MM) | 292.35 | -1.05 | -0.36% | 718,364.00 |
| 69 | LSTR | Landstar System, Inc. (MM) | 83.25 | -1.05 | -1.25% | 166,570.00 |
| 70 | USCR | U S Concrete, Inc. (MM) | 66.95 | -1.00 | -1.47% | 274,350.00 |
| 71 | JAZZ | Jazz Pharmaceuticals Plc - Ordinary Shares (MM) | 151.11 | -0.94 | -0.62% | 291,235.00 |
| 72 | QRVO | Qorvo, Inc. (MM) | 77.84 | -0.99 | -1.26% | 1,349,495.00 |
| 73 | TCBI | Texas Capital Bancshares, Inc. (MM) | 75.20 | -1.00 | -1.31% | 284,831.00 |
| 74 | INGN | Inogen, (MM) | 87.93 | -1.02 | -1.15% | 131,085.00 |
| 75 | HA | Hawaiian Holdings, Inc. (MM) | 49.75 | -1.00 | -1.97% | 637,067.00 |
| 76 | PLUS | Eplus Inc. (MM) | 76.90 | -0.95 | -1.22% | 115,416.00 |
| 77 | ANAB | Anaptysbio, Inc. (MM) | 25.70 | -1.00 | -3.75% | 56,587.00 |
| 78 | CNCE | Concert Pharmaceuticals, Inc. (MM) | 13.18 | -0.98 | -6.92% | 250,302.00 |
| 79 | ADBE | Adobe Systems Incorporated (MM) | 141.89 | -0.96 | -0.67% | 1,604,223.00 |
| 80 | EXPE | Expedia, Inc. (MM) | 144.58 | -0.96 | -0.66% | 1,130,896.00 |
| 81 | BCRX | Biocryst Pharmaceuticals, Inc. (MM) | 5.77 | -0.96 | -14.26% | 7,305,452.00 |
| 82 | RAVN | Raven Industries, Inc. (MM) | 34.05 | -0.95 | -2.71% | 167,322.00 |
| 83 | SRCL | Stericycle, Inc. (MM) | 82.40 | -0.95 | -1.14% | 472,386.00 |
| 84 | UG | United-Guardian, Inc. (MM) | 16.15 | -0.95 | -5.56% | 17,903.00 |
| 85 | NYNY | Empire Resorts, Inc. (MM) | 24.10 | -0.95 | -3.79% | 8,017.00 |
| 86 | PLSE | Pulse Biosciences, (MM) | 30.28 | -0.96 | -3.07% | 167,165.00 |
| 87 | ATVI | Activision Blizzard, (MM) | 58.28 | -0.94 | -1.59% | 7,019,197.00 |
| 88 | IRTC | Irhythm Technologies, Inc. (MM) | 34.01 | -0.91 | -2.61% | 286,741.00 |
| 89 | QCOM | Qualcomm Incorporated (MM) | 57.52 | -0.93 | -1.59% | 8,261,886.00 |
| 90 | LJPC | LA Jolla Pharmaceutical Company (MM) | 29.02 | -0.93 | -3.11% | 248,065.00 |
| 91 | ALDR | Alder Biopharmaceuticals, Inc. (MM) | 16.15 | -0.90 | -5.28% | 582,873.00 |
| 92 | HRTX | Heron Therapeutics, Inc. (MM) | 13.95 | -0.90 | -6.06% | 2,182,224.00 |
| 93 | GSUM | Gridsum Holding Inc. ADS (MM) | 11.85 | -1.05 | -8.14% | 99,479.00 |
| 94 | SKYW | Skywest, Inc. (MM) | 35.35 | -0.95 | -2.62% | 233,038.00 |
| 95 | NLNK | Newlink Genetics Corp. (MM) | 14.34 | -0.90 | -5.91% | 753,248.00 |
| 96 | IMKTA | Ingles Markets, Incorporated (MM) | 37.00 | -1.00 | -2.63% | 65,025.00 |
| 97 | GLYC | Glycomimetics, Inc. (MM) | 13.00 | -0.89 | -6.41% | 3,760,905.00 |
| 98 | VERI | Veritone, Inc. (MM) | 13.79 | -0.87 | -5.93% | 78,044.00 |
| 99 | YERR | Yangtze River Development Limited (MM) | 12.22 | -0.88 | -6.72% | 27,827.00 |
| 100 | CHRW | C.H. Robinson Worldwide, Inc. (MM) | 67.04 | -0.87 | -1.28% | 1,303,220.00 |
| 101 | ADSK | Autodesk, Inc. (MM) | 113.03 | -0.86 | -0.76% | 2,109,782.00 |
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