Affymetrix to Host Conference Call on February 3, 2010 to Announce Fourth Quarter and Fiscal 2009 Results

Affymetrix, Inc. (Nasdaq: AFFX) today announced that it will release operating results for the fourth quarter and fiscal year 2009 after close of the stock market on Wednesday, February 3, 2010.

Affymetrix' management team will host a conference call on February 3, 2010 at 2:00 P.M. PT to review its operating results. A live webcast can be accessed by visiting the Investor Relations section of www.affymetrix.com. Investors and other interested parties can also listen by dialing 866-500-AFFX (domestic) or 706-643-2771 (international).

A replay of this call will be available from 5:00 P.M. PT on February 3, 2010 until 8:00 P.M. PT on February 10, 2010, at 800-642-1687 (domestic) or 706-645-9291 (international). The conference identification number for the replays is 50159245. An archived webcast of the conference call will be available under the Investor Relations section of www.affymetrix.com.

About Affymetrix

Affymetrix technology is used by the world’s top pharmaceutical, diagnostic, and biotechnology companies, as well as leading academic, government and not-for-profit research institutes. More than 1,800 systems have been shipped around the world and more than 20,000 peer-reviewed papers have been published using the technology.

Affymetrix is headquartered in Santa Clara, Calif., and has manufacturing facilities in Cleveland, Ohio, and Singapore. The company has about 1,100 employees worldwide and maintains sales and distribution operations across Europe and Asia. For more information about Affymetrix, please visit the company’s website at www.affymetrix.com.

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