UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
 
 
FORM 6-K
 
 
REPORT OF FOREIGN PRIVATE ISSUER
PURSUANT TO RULE 13a-16 OR 15d-16
UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of October 2024

Commission File Number: 001-31368
 
 
SANOFI
(Translation of registrant’s name into English)
 
 
46, avenue de la Grande Armée, 75017 Paris, FRANCE
(Address of principal executive offices)


Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.
Form 20-F  ☒            Form 40-F  ☐





In October 2024, Sanofi issued the press release attached hereto as Exhibit 99.1 which is incorporated herein by reference.


Exhibit Index


Exhibit No.
                                               Description
Exhibit 99.1
Press release dated October 25, 2024: Sanofi Q3: 15.7% sales growth boosted by earlier-than-anticipated vaccine sales; 2024 business EPS guidance raised due to strong business performance




SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Dated: October 25, 2024SANOFI
By:                              /s/ Alexandra Roger
Name:Alexandra Roger
Title:Head of Legal Corporate & Finance


Press Release image1.jpg

Sanofi Q3: 15.7% sales growth boosted by earlier-than-anticipated vaccine sales; 2024 business EPS guidance raised due to strong business performance
Paris, October 25, 2024
Q3 sales growth of 15.7% at CER and business EPS(1) of €2.86
•Dupixent sales up 23.8% to €3,476 million; full-year 2024 target of ~€13 billion confirmed
•Pharma launches up 67.1% to €727 million, led by ALTUVIIIO, Nexviazyme and Rezurock
•Vaccines sales up 25.5%, boosted by phasing of flu sales, and by Beyfortus due to approved extra capacity
•Opella up 7.9%, driven by the Qunol acquisition
•Research and Development expenses grew 12.7%
•Selling, general and administrative expenses grew 6.4%, substantially below sales growth, having a positive impact on profitability
•Business EPS(1) of €2.86, +12.2% reported and +17.6% at CER and IFRS EPS of €2.25, +11.9% reported
Q3 pipeline progress
•Four regulatory approvals: Dupixent COPD (US, CN), Dupixent CRSwNP adolescents (US), and Sarclisa NDMM, TI (US)
•Four positive phase 3 data readouts: Dupixent BP, Dupixent CSU, tolebrutinib nrSPMS, and Sarclisa NDMM, TE
Opella (consumer healthcare)
•On October 21, Sanofi and CD&R entered exclusive negotiations to transfer a controlling stake of Opella.*
2024 business EPS(1) guidance
•On October 21, 2024, the 2024 business EPS(1) guidance was upgraded to growth of at least a low single-digit percentage at CER(2) supported by the underlying strong business performance. This reflects the new scope of guidance excluding Opella detailed in the October 21, 2024 press release. Applying the average October 2024 exchange rates, the currency impact on 2024 business EPS(1) is estimated to be -5.5% to -6.5%.
Paul Hudson, Chief Executive Officer: “We reached almost 16% sales growth in the third quarter, illustrating the underlying strength of our portfolio. Our performance was boosted by the phasing of flu and Beyfortus, while we saw steady growth of 67% for our launch medicines as well as volume-driven growth by Dupixent. Dupixent is now approved as the first-ever biologic medicine to treat COPD across the EU, China, and the US allowing us to bring this innovative new treatment to hundreds of thousands of patients. Our pipeline-driven transformation continued to progress with the delivery of four new approvals and four positive phase 3 data readouts, including for tolebrutinib in secondary progressive multiple sclerosis, a disease with significant unmet medical need. We entered exclusive negotiations with CD&R on a controlling stake in Opella, allowing Sanofi to focus on innovative medicines and vaccines. Based on the strong business performance in the quarter, we recently upgraded our business EPS guidance. This momentum is already paving the way for the strong rebound we said we expected in 2025 business EPS.”
Q3 2024ChangeChange
at CER		YTD 2024ChangeChange
at CER
IFRS net sales reported€13,438 m+12.3 %+15.7 %€34,647 m+7.8 %+11.1 %
IFRS net income reported€2,815 m+11.5 %— €5,061 m-15.0 %— 
IFRS EPS reported€2.25 +11.9 %— €4.05 -14.9 %— 
Free cash flow(3)
€3,327 m+79.5 %— €3,872 m-22.3 %— 
Business operating income€4,607 m+14.4 %+19.9 %€10,263 m+1.7 %+8.8 %
Business net income(1)
€3,585 m+12.2 %+17.5 %€7,965 m-1.3 %+5.5 %
Business EPS(1)
€2.86 +12.2 %+17.6 %€6.37 -1.2 %+5.6 %
Changes in net sales are expressed at constant exchange rates (CER) unless stated otherwise (definition in Appendix 7). (1) In order to facilitate an understanding of
operational performance, Sanofi comments on the business net income statement. Business net income is a non-IFRS financial measure (definition in Appendix 7). The
consolidated income statement for Q3 and YTD 2024 is provided in Appendix 3 and a reconciliation of reported IFRS net income to business net income is set forth in
Appendix 4. (2) Based on 2023 preliminary business EPS of €7.25 excluding Opella. (3) Free cash flow is a non-IFRS financial measure (definition in Appendix 7). *The
proposed transaction is subject to finalization of definitive agreements, completion of the appropriate social processes and subject to customary closing conditions.
1

Q3 and YTD 2024 summary
A conference call and webcast for investors and analysts will begin at 14:00 CEST. Details can be accessed via sanofi.com, including presentation slides.
— — —
The performance shown in this press release covers the three-month period to September 30, 2024 (the quarter or Q3 2024) and the nine-month period to September 30, 2024 (the year to date or YTD 2024) compared to the three-month period to September 30, 2023 (Q3 2023) and the nine-month period to September 30, 2023 (the year to date or YTD 2023) respectively. All percentage changes in sales in this press release are at CER1, unless stated otherwise.
— — —
In Q3 2024, sales were €13,438 million and increased by 15.7%. Exchange rate movements had a negative effect of 3.4 percentage points (pp); therefore, as reported, sales increased by 12.3%. In YTD 2024, sales were €34,647 million and increased by 11.1%. Exchange rate movements had a negative effect of 3.3pp; reported, sales increased by 7.8%. The commentary below emphasizes the recent quarterly performance unless stated otherwise.
Sales by segment and business
Net sales (€ million)Q3 2024Change
at CER		% of
 total sales		YTD 2024Change
at CER		% of
 Total sales
Biopharma12,167 +16.6 %90.5 %30,545 +11.5 %88.2 %
   Pharma8,365 +13.0 %62.2 %24,424 +10.7 %70.5 %
   Vaccines3,802 +25.5 %28.3 %6,121 +14.5 %17.7 %
Opella1,271 +7.9 %9.5 %4,102 +8.8 %11.8 %
Total13,438 +15.7 %100 %34,647 +11.1 %100 %
Sales by geography
Net sales (€ million)Q3 2024Change
at CER		YTD 2024Change
at CER
United States6,886 +23.6 %15,953 +17.6 %
Europe2,886 +6.6 %7,768 +0.2 %
Rest of World3,666 +10.3 %10,926 +10.8 %
 of which China757 +3.6 %2,279 +3.0 %
US sales were €6,886 million and increased by 23.6%. The strong performance was driven by new launches, including Beyfortus, and by Dupixent, insulins and all Vaccines businesses with sales of legacy medicines slightly offsetting growth.
Europe sales were €2,886 million and increased by 6.6%. Growth was driven by new launches, Dupixent, and Vaccines. Some legacy medicines declined, including Aubagio from generic competition.
Rest of World sales were €3,666 million and increased by 10.3%. Performance was led by Dupixent and Vaccines, and partly by new launches and Toujeo. China sales were €757 million and increased by 3.6%, driven by strong performance by Dupixent mostly offset by Lovenox and Other medicines. With higher inflation, the contribution of Argentina to the total Sanofi sales growth rate was 1.2pp.
Business operating income
In Q3 2024, business operating income (BOI) was €4,607 million and increased by 14.4% (19.9% at CER). The ratio of BOI to net sales was 34.3% and increased by 0.6pp (34.9% at CER, up by 1.2pp). This improvement was mainly driven by a higher gross margin and operating leverage. In YTD 2024, BOI was €10,263 million and increased by 1.7% (8.8% at CER). The ratio of BOI to net sales was 29.6% and decreased by 1.8pp (30.7% at CER, down by 0.7pp).
Business development
Business development, including strategic investments in external innovation is an integrated part of Sanofi’s efforts to continuously access optionality on new and promising scientific developments and platforms and replenish the pipeline.
In September, Sanofi made an equity investment of $40 million in Ventyx Biosciences, Inc. (NASDAQ: VTYX), a clinical-stage biopharmaceutical company in autoimmune and inflammatory disorders. Ventyx granted Sanofi an exclusive right of first negotiation to an NLRP3 inhibitor. Sanofi also participated in the rights issue for $10 million in Vicore Pharma Holding AB (STO: VICO), a clinical-stage pharmaceutical company in respiratory and fibrotic diseases, including idiopathic pulmonary fibrosis.
1 See Appendix 7 for definitions of financial indicators.
2

Further in September, Sanofi entered an exclusive licensing agreement with RadioMedix, Inc. and Orano Med for the late-stage project, AlphaMedixTM (212Pb-DOTAMTATE), for the treatment of adult patients with unresectable or metastatic, progressive somatostatin-receptor expressing neuroendocrine tumors, a rare cancer.
In August, Sanofi made two equity investments, including $30 million in MeiraGTx Holdings plc (NASDAQ: MGTX), a clinical-stage genetic medicine company, and $40 million in AnaptysBio (NASDAQ: ANAB), a clinical-stage biotechnology company focused on immunology therapeutics, including in rheumatoid arthritis and ulcerative colitis.
Biopharma
The Biopharma segment includes Pharma and Vaccines. In Q3 2024, sales were €12,167 million and increased by 16.6%, driven by continued strong performance of new launches and Dupixent growth. The divestments of medicines/portfolio streamlining had a negative impact of 0.7pp. In YTD 2024, sales were €30,545 million and increased by 11.5% driven by the same aforementioned factors.
Pharma
Pharma launches
Net sales (€ million)Q3 2024Change
at CER		YTD 2024Change
at CER
ALTUVIIIO172 +278.3 %452 +600.0 %
Nexviazyme/Nexviadyme
163 +53.6 %483 +69.7 %
Rezurock131 +57.8 %338 +50.9 %
Sarclisa
114 +23.7 %341 +29.5 %
Cablivi
63 +12.5 %176 +4.7 %
Xenpozyme41 +51.9 %113 +75.4 %
Enjaymo
28 +81.3 %83 +75.5 %
Tzield15 +66.7 %36 +140.0 %
Total727 +67.1 %2,022 +78.2 %
ALTUVIIIO (hemophilia A) sales were €172 million of which more than 90% were in the US. Growth continued to be driven by patient switches from existing factor medicines, including some from Eloctate, and from non-factor medicines. The hemophilia A franchise (ALTUVIIIO + Eloctate) sales were €268 million and increased by 63.3%, increasing market share.
Nexviazyme/Nexviadyme (Pompe disease) sales were €163 million and increased by 53.6%. Growth was higher in Europe (104.3%) and the Rest of World (121.4%). Growth in the US was 24.7% where most patients have already converted from Myozyme/Lumizyme. The Pompe franchise (Nexviazyme/Nexviadyme + Myozyme/Lumizyme) sales were €331 million and increased by 15.2%. Nexviazyme/Nexviadyme sales now accounts for 49% of the total Pompe franchise.
Rezurock (chronic graft-versus-host disease) sales were €131 million and increased by 57.8%, driven by fast uptake in launch countries, including the US, China, and the UK, and persistence is use by patients.
Sarclisa (multiple myeloma) sales were €114 million and increased by 23.7%. Growth was driven by market share gains in Europe, and by the Rest of World, specifically Japan.
Cablivi (acquired thrombotic thrombocytopenic purpura) sales were €63 million and increased by 12.5%, driven by patient growth in the US.
Xenpozyme (acid sphingomyelinase deficiency) sales were €41 million and increased by 51.9%, driven by more patients across all regions.
Enjaymo (cold agglutinin disease) sales were €28 million and increased by 81.3%, driven by all regions. On October 4, 2024, Recordati announced the acquisition of global rights to Enjaymo. The transaction is expected to close this quarter.
Tzield (delay onset of type 1 diabetes) sales were €15 million, a sequential increase from Q2 2024 of €4 million, mostly reflecting continued growth in infusions supported by ongoing efforts to increase awareness and screening.
Immunology
Net sales (€ million)Q3 2024Change
at CER		YTD 2024Change
at CER
Dupixent
3,476 +23.8 %9,614 +25.9 %
Dupixent sales were €3,476 million and increased by 23.8%. In the US, sales were €2,556 million and increased by 19.1%. Growth was driven by strong demand in the approved indications of atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyposis, eosinophilic esophagitis and prurigo nodularis. In Europe, Dupixent sales were €417 million and increased by 35.1% reflecting continued growth in all approved indications and emerging sales in COPD. In the Rest of World, sales were €503 million and increased by 41.9%, driven mainly by sales in Japan and China. In YTD 2024, Dupixent sales were €9,614 million and increased by 25.9%, on track to achieve ~€13 billion in sales in 2024 at constant exchange rates. More than one million patients are currently being treated with Dupixent globally.
3

Other main medicines
Net sales (€ million)Q3 2024Change
at CER		YTD 2024Change
at CER
Lantus431 +33.8 %1,189 +10.6 %
Toujeo
303 +18.1 %937 +15.6 %
Fabrazyme
253 +4.0 %779 +8.0 %
Lovenox233 -1.2 %751 -7.1 %
Plavix230 +8.3 %703 +5.6 %
Myozyme/Lumizyme
168 -7.5 %539 -11.1 %
Cerezyme
164 +8.0 %571 +17.0 %
Alprolix
148 +8.7 %419 +6.3 %
Praluent126 +10.4 %373 +23.7 %
Thymoglobulin121 +4.1 %367 +4.9 %
Eloctate96 -19.2 %287 -20.7 %
Aubagio
92 -52.3 %301 -62.8 %
Cerdelga81 +12.3 %246 +11.7 %
Lantus sales were €431 million and increased by 33.8%. US sales were €175 million and increased by 162.7%, benefiting from another quarter of windfall sales due to the continued unavailability of a competing medicine as well as a lower base of comparison from net-price adjustments.
Toujeo sales were €303 million and increased by 18.1%, mainly driven by the Rest of World, including China where Toujeo continued to increase its basal insulin market share. US sales benefited from the continued unavailability of a competing medicine.
Fabrazyme sales were €253 million and increased by 4.0%, mainly driven by growth in the number of patients.
Lovenox sales were €233 million and decreased by 1.2%, reflecting the impact from volume-based procurement in China and biosimilar competition in the EU.
Plavix sales were €230 million and increased by 8.3%, underpinned by increased use and market share in the Rest of World, including China from the inclusion in volume-based procurement.
Myozyme/Lumizyme sales were €168 million and decreased by 7.5% due to the conversion to Nexviazyme/Nexviadyme.
Cerezyme sales were €164 million and increased by 8.0%, driven by growth in the number of patients in the Rest of World. The Gaucher disease franchise (Cerezyme + Cerdelga) sales were €245 million and increased by 9.2%.
Alprolix sales were €148 million and increased by 8.7%, driven by supply sales to the partner.
Praluent sales were €126 million and increased by 10.4%, underpinned by Europe.
Thymoglobulin sales were €121 million and increased by 4.1%, mostly reflecting increased sales in the Rest of World.
Eloctate sales were €96 million and decreased by 19.2%, mainly due to patients converting to ALTUVIIIO in the US.
Aubagio sales were €92 million and decreased by 52.3%, reflecting the loss of exclusivity starting in the US in March 2023 followed by Europe in September 2023. Aubagio sales are expected to continue to decrease albeit at a slower rate.
Cerdelga sales were €81 million and increased by 12.3%, primarily driven by the US and an increased number of patients.
Vaccines
Net sales (€ million)Q3 2024Change
at CER		YTD 2024Change
at CER
Influenza vaccines1,913 +10.9 %2,101 +12.3 %
Polio/Pertussis/Hib vaccines incl. Boosters760 +2.0 %2,108 -1.2 %
RSV (Beyfortus)645 +381.8 %845 +537.2 %
Meningitis, Travel and endemic vaccines 485 +13.1 %1,067 +7.9 %
Total3,802 +25.5 %6,121 +14.5 %
Vaccines sales were €3,802 million and increased by 25.5%, driven by Beyfortus rollout and boosted by the earlier phasing of both flu and Beyfortus deliveries. In YTD 2024, sales were €6,121 million and increased by 14.5%, driven mainly by Beyfortus, partly offset by the absence of COVID-19 sales compared to €226 million in YTD 2023.
Influenza vaccines sales reached €1,913 million and increased by 10.9%, boosted by earlier-than-anticipated deliveries.
Polio/Pertussis/Hib (PPH) vaccines sales were €760 million and increased by 2.0%, with a favorable benefit from slightly increased Boosters demand in several countries.
Beyfortus sales were €645 million, driven by early deliveries in the US and rollout in a number of countries, including Canada, France, Germany, Spain, Portugal, Belgium, and Ireland. In collaboration with AstraZeneca, responsible for manufacturing, increased supply was enabled by additional capacity after a second, external filling line was licensed.
Meningitis, Travel and endemic vaccines sales were €485 million and increased by 13.1% reflecting growth in all regions. In the US, Meningitis benefited from favorable Centers for Disease Control and Prevention buying patterns.
4

Biopharma business operating income
In Q3 2024, Biopharma BOI was €4,340 million and increased by 15.8% (21.2% at CER). The ratio of BOI to net sales was 35.7% and increased by 0.7pp (36.3% at CER, up by 1.3pp). This improvement was mainly driven by a higher gross margin and operating leverage. In YTD 2024, BOI was €9,271 million and increased by 3.4% (9.8% at CER). The ratio of BOI to net sales was 30.4% and decreased by 1.4pp (31.3% at CER, down by 0.5pp).
5

Pipeline update
Sanofi has 78 projects in a pipeline across four main disease areas (Immunology, Rare diseases, Neurology, and Oncology) and Vaccines, including 36 potential new medicines (NMEs) and vaccines. The following section highlights significant developments in the late- and mid-stage pipeline in the quarter:
Highlights
Regulatory approvalsDupixent – COPD (US, CN)
Dupixent – CRSwNP adolescents (US)
Sarclisa – NDMM, TI (IMROZ study) (US)
Regulatory recommendationsDupixent – EoE children (EU)
Cerdelga – GD1 children (EU)
Regulatory submission acceptances
MenQuadfi – Meningitis six weeks+ (US)
Rezurock – cGvHD, 3L (EU)
Phase 3 data readouts
Dupixent – CSU (Study C) (primary endpoint met)
Dupixent – CPUO (Study A) (primary endpoint not met)
Dupixent – BP (primary endpoint met)
tolebrutinib – RMS (primary endpoint not met)
tolebrutinib – nrSPMS (primary endpoint met)
losmapimod – FSHD (primary endpoint not met)
Sarclisa – NDMM, TE (HD7 study) (primary endpoint met)
Immunology
Dupixent (dupilumab)
•The US Food and Drug Administration (FDA) approved Dupixent as an add-on maintenance treatment of adults with inadequately controlled chronic obstructive pulmonary disease (COPD) and an eosinophilic phenotype. Dupixent is the first biologic medicine approved in the US to treat these patients.
The National Medical Products Administration in China approved Dupixent as an add-on maintenance treatment for adults with uncontrolled COPD characterized by raised blood eosinophils. Specifically, the approval covers patients already on a combination of an inhaled corticosteroid (ICS), a long-acting beta2-agonist (LABA) and a long-acting muscarinic antagonist (LAMA), or on a combination of a LABA and a LAMA if ICS is not appropriate. Dupixent for the treatment of COPD has now been approved in more than 30 countries worldwide, including the 27 countries in the EU.
•The FDA approved Dupixent as an add-on maintenance treatment for adolescent patients aged 12 to 17 years with inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP). This approval expands the initial FDA approval in CRSwNP from June 2019 for patients aged 18 years and older. The FDA evaluated Dupixent for this expanded indication under a priority review.
•The European Medicines Agency (EMA)’s Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion recommending the expanded approval of Dupixent in the EU for eosinophilic esophagitis (EoE) in children down to one year of age. The recommendation is for children aged one to 11 years who weigh at least 15 kg and who are inadequately controlled by, intolerant to, or who are not candidates for conventional medicinal therapy, supported by the two-part (Part A and B) EoE KIDS phase 3 study (clinical study identifier: NCT04394351). The European Commission is expected to announce a final decision in the coming months. Dupixent is already approved in the EU for certain adults and adolescents aged 12 years and older with EoE.
•Dupixent’s confirmatory LIBERTY-CUPID Study C phase 3 study (clinical study identifier: NCT04180488) met the primary and key secondary endpoints for the treatment of patients with uncontrolled, biologic-naïve chronic spontaneous urticaria (CSU) receiving background therapy with antihistamines. CSU is a chronic skin condition that causes sudden and debilitating hives and persistent itch, which can impact quality of life. This positive study confirms results from Study A, the first phase 3 study of Dupixent in this setting. Earlier this year, Japan was the first country in the world to approve and launch Dupixent for adult and adolescent CSU patients based on the results from Study A. The indication is under review in the EU based on results from Study A and Study B (patients uncontrolled on standard-of-care H1 antihistamines and refractory to omalizumab), and the new Study C data will support regulatory resubmission in the US by the end of the year.
•The LIBERTY-CPUO-CHIC Study A phase 3 study (clinical study identifier: NCT05263206) evaluating the use of Dupixent in adults with uncontrolled and severe chronic pruritus of unknown origin (CPUO) did not achieve statistical significance in its primary itch responder endpoint (despite favorable numerical improvements), but showed nominally significant improvements in all other itch endpoints. The Dupixent phase 3 study program in CPUO consists of Study A and Study B. Study B is planned to initiate as a subsequent pivotal study.
6

•Dupixent’s pivotal LIBERTY-BP phase 3 study (clinical study identifier: NCT04206553) in bullous pemphigoid (BP) met the primary and all key secondary endpoints evaluating its use in adults with moderate-to-severe disease. Dupixent was previously granted orphan drug designation by the FDA for BP, which applies to medicines intended for the treatment of rare diseases that affect fewer than 200,000 people in the US. This study will support regulatory submissions around the world in the first half of 2025. BP is a chronic and relapsing disease, characterized by intense itch and blisters, reddening of the skin, and painful chronic lesions. The blisters and rash can form over much of the body and cause the skin to bleed and crust, resulting in patients being more prone to infection and affecting their daily functioning.
Rezurock (belumosudil)
The EMA accepted for review the regulatory submission of Rezurock for the treatment of chronic graft-versus-host disease (cGVHD), third line (3L). The EMA granted an orphan designation in 2019 for the treatment of cGVHD, and Rezurock, first approved by the FDA in 2021, is now approved in 14 other countries, including China, the UK and Canada.
amlitelimab (OX40L mAb)
•The amlitelimab proof-of concept TIDE-Asthma phase 2 study (clinical study identifier: NCT05421598) in moderate-to-severe asthma has a 60-week double-blind placebo-controlled period, in which patients are dosed once every four weeks during the initial 24 weeks and once every 12 weeks for the subsequent 36 weeks. Sanofi anticipates the internal data availability of top-line results for the full and completed 60-week treatment and follow-up period to move over the year-end and into H1 2025.
•The ASPIRION phase 2 study (clinical study identifier: NCT06557772) assessing efficacy and safety of subcutaneous injections of amlitelimab in adults with non-responsive celiac disease has commenced dosing its first patient.
lunsekimig (IL13xTSLP Nanobody® VHH)
A proof-of-concept phase 2 study (clinical study identifier: NCT06454240) assessing efficacy and safety of lunsekimig compared with placebo in adults with CRSwNP has commenced dosing its first patient.
Rare diseases
ALTUVIIIO (efanesoctocog alfa)
The New England Journal of Medicine published full results from the second pivotal phase 3 study, XTEND-Kids (clinical study identifier: NCT04759131), highlighting efficacy, safety, and the pharmacokinetic profile of ALTUVIIIO, as a first-in-class, high-sustained factor VIII replacement therapy, for adults and children with hemophilia A for routine prophylaxis and on-demand treatment to control bleeding episodes as well as for perioperative management (surgery). In May, FDA updated the label for ALTUVIIIO to include the results from the XTEND-Kids phase 3 study in children with hemophilia A.
fitusiran (RNAi targeting antithrombin)
Sanofi’s collaborator Siemens Healthineers has submitted for FDA review the INNOVANCE® Antithrombin Assay as a companion diagnostic that will measure antithrombin levels in people living with hemophilia who are prescribed fitusiran, a potential antithrombin-lowering medicine for the prophylactic treatment of people with hemophilia A or B, with or without inhibitors. The prescription drug user fee act (PDUFA) action date for fitusiran is March 28, 2025.
rilzabrutinib (BTK inhibitor)
During the quarter, a single-arm phase 2 study (clinical study identifier: NCT05002777) of rilzabrutinib in warm autoimmune hemolytic anemia read out positively with clinically meaningful outcomes on response rate and additional disease markers. Data are planned to be shared at a medical meeting later this year. The results of this study build on the successful phase 3 study in immune thrombocytopenic purpura (ITP) and reinforce its efficacy in autoimmune cytopenias.
losmapimod (p38α/β MAPK inhibitor)
Fulcrum announced that the losmapimod REACH phase 3 study (clinical study identifier: NCT05397470) assessing efficacy and safety in adults with facioscapulohumeral muscular dystrophy (FSHD) did not meet the primary endpoint.
Cerdelga (eliglustat)
The CHMP adopted a positive opinion recommending the expanded approval of Cerdelga to include treatment of pediatric patients with Gaucher disease type 1 (GD1), who are six years and older with a minimum body weight of 15 kg, who have been previously treated with enzyme replacement therapy, and who are CYP2D6 poor metabolizers, intermediate metabolizers or extensive metabolizers. The EMA granted an orphan designation in 2007 for the treatment of GD1, and Cerdelga is approved in the US and EU for adults patients with GD1.
7

Neurology
tolebrutinib (BTK inhibitor)
Positive results from the HERCULES phase 3 study (clinical study identifier: NCT04411641) showed that tolebrutinib met the primary endpoint of improvement over placebo in delaying time to onset of confirmed disability progression (CDP) in people with non-relapsing secondary progressive multiple sclerosis (nrSPMS). Specifically, tolebrutinib delayed the time to onset of 6-month CDP by 31% (HR 0.69; 95% CI 0.55-0.88; p=0.0026). Further analysis of secondary endpoints showed that the number of participants who experienced confirmed disability improvement increased by nearly two-fold, 10% with tolebrutinib compared to 5% with placebo (HR 1.88; 95% CI 1.10 to 3.21; nominal p=0.021).
In the HERCULES study, nrSPMS was defined at baseline as having a SPMS diagnosis with an expanded disability status scale score between 3.0 and 6.5, no clinical relapses for the previous 24 months and documented evidence of disability accumulation in the previous 12 months. Preliminary analysis of liver safety was consistent with previous tolebrutinib studies.
Results from the GEMINI 1 and 2 phase 3 studies (clinical study identifiers: NCT04410978/NCT04410991, respectively) evaluating tolebrutinib did not meet the primary endpoint of reducing annualized relapse rate, compared to Aubagio, a standard of care treatment, in people with relapsing MS (RMS). However, analysis of the key secondary endpoint of pooled 6-month CDW data showed a considerable delay in time to onset, which supports the CDP data observed in HERCULES.
These results were presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) conference 2024 in Copenhagen, Denmark. Sanofi expects making regulatory submissions in SPMS starting this quarter.
frexalimab (CD40L mAb)
New efficacy and safety data at 18 months from the phase 2 open-label extension study of frexalimab (clinical study identifier: NCT04879628), for the treatment of RMS, demonstrated sustained reduction of disease activity as measured by MRI, with stable clinical surrogate endpoints. Frexalimab remained well tolerated with no new safety signals. These results were also presented at ECTRIMS 2024 and support the ongoing clinical development with two phase 3 studies in RMS and one phase 3 study in nrSPMS.
oditrasertib (RIPK1 inhibitor)
The K2 phase 2 study (clinical study identifier: NCT05630547) evaluating safety and the efficacy of oditrasertib on serum neurofilament light chain levels in patients with MS was discontinued based on not meeting the primary and key secondary endpoints.
Oncology
Sarclisa (isatuximab)
•The FDA approved Sarclisa in combination with bortezomib, lenalidomide, and dexamethasone (VRd) as a first-line treatment option for adult patients with newly diagnosed multiple myeloma who are not eligible for autologous stem cell transplant (NDMM, TI). Sarclisa is the first anti-CD38 therapy in combination with standard-of-care VRd to significantly reduce disease progression or death (by 40%, HR 0.60; 95% CI: 0.44 to 0.81, p=0.0009) compared to VRd alone for patients with NDMM not eligible for transplant. Other regulatory submissions based on the IMROZ phase 3 study (clinical study identifier: NCT03319667) in this third indication for Sarclisa are currently under review in the EU, Japan, and China.
•New results from the two-part, double-randomized, German-speaking Myeloma Multicenter Group (GMMG)-HD7 phase 3 study (clinical study identifier: NCT03617731) showed that Sarclisa in combination with lenalidomide, bortezomib, and dexamethasone (RVd) during induction therapy in NDMM, transplant-eligible (TE), significantly prolonged progression-free survival from first randomization, resulting in a statistically significant and clinically meaningful reduction in disease progression or death, compared to RVd induction regardless of the maintenance regimen. Full results will be submitted for presentation at a forthcoming medical meeting with regulatory submission later this year in the EU.
Vaccines
Beyfortus (nirsevimab)
New data from the HARMONIE phase 3b study (clinical study identifier: NCT05437510) demonstrated that Beyfortus consistently reduced respiratory syncytial virus (RSV) hospitalizations by 82.7% (95% CI: 67.8% to 91.5%) through six months (180 days) with no evidence of waning protection after dosing compared to no intervention. Beyfortus also reduced RSV lower respiratory tract disease in infants by 87.2% (95% CI: 81.7% to 91.1%), regardless of the healthcare setting (outpatient, emergency department or inpatient) compared to no RSV intervention, according to new real-world
8

evidence from the Beyfortus Effectiveness Against medically attended RSV events in infants (BEAR) study following 31,900 US healthy infants in their first RSV season. These findings confirm the significant positive efficacy and safety profile that Beyfortus demonstrated in multi-country, real-world conditions over a long period of time.
MenQuadfi (quadrivalent meningococcal vaccine)
The FDA accepted for review the supplemental biologics license application for MenQuadfi (clinical study identifier: NCT03547271) for the potential extension of the indication to include children aged six weeks to 23 months through active immunization for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, W, and Y. The PDUFA date is May 23, 2025.
NVX-CoV2705 (COVID-19 vaccine)
The EMA approved and the FDA authorized for emergency use the updated Novavax protein-based COVID-19 vaccine. The vaccine has been refined to also target the JN.1 parent strain of the COVID-19 virus. A regulatory submission for full approval in the US is being prepared. In 2025, Sanofi will take on the commercialization from Novavax.
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Anticipated major upcoming pipeline milestones
Medicine/vaccineIndicationDescription
H2 2024Dupixent
EoE children
Regulatory decision (EU)
CSU (Study C)Regulatory submission (US)
rilzabrutinibITPRegulatory submission (US, EU)
IgG4-related diseasePhase 2 data
duvakitugInflammatory bowel diseasePhase 2 data
tolebrutinibSecondary progressive MSRegulatory submission (US)
CerezymeGaucher disease type 3Regulatory submission (US)
CerdelgaGaucher disease type 1 childrenRegulatory decision (EU)
SarclisaMDMM, TE (HD7)
Regulatory submission (EU)
MM, relapsed/refractory (R/R) (IRAKLIA study), subcutaneousPhase 3 data
H1 2025DupixentCOPDRegulatory decision (JP)
BPRegulatory submission
CSURegulatory decision (EU)
amlitelimabAsthmaPhase 2 data
Hidradenitis suppurativa (HS)Phase 2 data
Oral TNFR1siPsoriasisPhase 2 data
TNFa/OX40LHSPhase 2 data
IRAK4 degraderHSPhase 2 data
ADPhase 2 data
fitusiranHemophilia A/BRegulatory decision (US)
rilzabrutinib
ITP
Regulatory submission (JP, CN)
tolebrutinibSecondary progressive MSRegulatory submission (EU)
Sarclisa
NDMM, TI (IMROZ)
Regulatory decision (EU, JP, CN)
MM, R/R (IRAKLIA), subcutaneousRegulatory submission (US, EU)
MenQuadfiMeningitis six weeks+Regulatory decision (US)
SP0087RabiesPhase 3 data
H2 2025itepekimabCOPDPhase 3 data
Regulatory submission (US, EU)
lunsekimigAsthmaPhase 2 data
Oral TNFR1siRheumatoid arthritisPhase 2 data
AAT recombinant Fc Alpha-1 antitrypsin deficiencyPhase 2 data
fitusiranHemophilia A/BRegulatory decision (CN)
venglustatFabry diseasePhase 3 data
Gaucher disease type 3Phase 3 data
tolebrutinibPrimary progressive MSPhase 3 data
Regulatory submission (US)
Rezurock
Chronic graft-versus-host disease, third line
Regulatory decision (EU)
Tzield
Delay onset of type 1 diabetes
Regulatory decision (CN)
SP0087RabiesRegulatory submission (US)
SP0230MeningitisPhase 2 data
SP0256RSV older adultsPhase 2 data
An update of the Sanofi pipeline as of September 30, 2024, is available at: https://www.sanofi.com/en/our-science/our-pipeline.
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Opella (consumer healthcare)
Net sales (€ million)Q3 2024Change
at CER		YTD 2024Change
at CER
Wellness brands 574 +24.9 %1,832 +22.5 %
Seasonal symptoms & pain relief538 -3.1 %1,754 -1.1 %
Others159 -4.1 %516 +1.5 %
Total1,271 +7.9 %4,102 +8.8 %
Opella sales were €1,271 million and increased by 7.9%. Growth was enhanced by the acquisition of Qunol (c.5%), organic sales growth (c.3%), and industrial sales transferred from Biopharma in January 2024 (c.2%) but tempered by divestments (c.2%). In North America, growth benefited mainly from the Qunol acquisition with some impacts from lower demand in the Seasonal symptoms & pain relief category, more specifically in allergy. Europe delivered steady sales with improving in-market performance supported by price, offset by negative volume impact. In the Rest of World, sales were driven by the Wellness category. In YTD 2024, sales increased by 8.8%, driven by Qunol (c.6%), organic growth (c.3%) and industrial sales (c.2%). This momentum was partially offset by the negative effect of divestments linked to strategic portfolio rationalization (c.2%).
Opella business operating income
In Q3 2024, Opella BOI was €287 million and increased by 1.1% (12.0% at CER). The ratio of BOI to net sales was 22.6% and decreased by 0.2pp (23.7% at CER, up by 0.9pp). This development was mainly driven by a higher gross margin, lower R&D expenses, and higher other operating income partly offset by higher SG&A expenses. In YTD 2024, BOI was €1,026 million and decreased by 9.5% (increased by 1.7% at CER). The ratio of BOI to net sales was 25.0% and decreased by 3.6pp (26.7% at CER, down by 1.9pp).
For future Opella reporting and accounting, please refer to the separate press release from October 21, 2024.
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Corporate Social Responsibility update at the end of Q3 2024
Access
Living wage pledge
In many countries, minimum wages are insufficient to guarantee that workers and their families can meet basic needs. Sanofi is proud to go beyond the minimum by committing to a living wage for all employees.
Since 2023, Sanofi has adopted the Fair Wage Network’s methodology to ensure every employee earns above their respective local living wage benchmarks. Providing a living wage not only improves employees’ health and well-being but also strengthens local economies.
As a Living Wage employer and a proud signatory of the UN Global Compact’s Forward Faster initiative, Sanofi is setting a new standard.
Sanofi’s commitment to fair wages extends beyond the workforce, and the company will continue to advocate for living wages across key supply chain partners.
Raise your voice: the annual DE&I report
In the annual diversity, equity and inclusion (DE&I) Report, Sanofi takes stock of progress on the three pillars of the DE&I strategy.
On the ‘building representative leadership’ pillar:
•45%1 of senior leaders are women (2025 ambition: 50%)
•42%1 of executives are women (2025 ambition: 40%+)
On the ‘creating an inclusive work environment’ pillar:
•Grade of 8.1 out of 10 on the internal DE&I index in the latest “Your voice” survey, with a 2025 target score above 8 (grade of 8 in 2022)
•95% of audited workplaces ranked bronze or higher for accessibility, with a 2025 ambition of 100%
On the ‘beyond the workplace’ pillar:
•€1.45 billion spend is made with small and diverse businesses with a 2025 ambition of €1.5 billion
•all clinical studies in the US have set diversity targets
(1) As of Q3 2024
“Cancer & Work: Acting Together": a holistic approach to care for Sanofi employees
”Cancer & Work: Acting Together" has been rolled out internationally since early 2024. It is a holistic approach that is based on three pillars: a human resources policy that offers a high degree of social protection, an international network of employees trained in counseling who run confidential listening and exchange spaces for personalized support, and active communication that sheds light on the issues of cancer and other critical illnesses.
•Since January 1, 2024, the program's flagship measure - 12 months' salary, social protection and employment guarantee - has been in place for all employees affected by cancer, regardless of their geographical location. In the interests of fairness and inclusion, Sanofi has also extended this coverage to other serious illnesses.
•To date, the international network has 113 Sanofi employees in 36 countries, all of whom have completed a 10-hour training program in ”Cancer & Work” counseling. The network is structured geographically to offer locally-adapted actions and support, and is also connected globally on a monthly basis to develop its knowledge and practices.
•Finally, a worldwide awareness campaign has been launched in October to raise awareness amongst employees on the challenges of prevention, screening and “Cancer & Work” support, to promote the program and to develop an inclusive culture.
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ESG ratings
See Sanofi’s latest ESG rankings below:
image.jpg
13

Q3 and YTD 2024 financial results
Business net income2
Net sales were €13,438 million and increased by 12.3% (15.7% at CER). In YTD 2024, net sales were €34,647 million and increased by 7.8% (11.1% at CER).
Other revenues were €719 million and decreased by 2.0% (0.7% at CER), including VaxServe sales of non-Sanofi products of €545 million (decreased by 11.4% at CER). In YTD 2024, other revenues were €2,008 million and decreased by 4.0% (0.8% at CER), including VaxServe sales of non-Sanofi products of €1,399 million (decreased by 3.6% at CER).
Gross profit was €10,074 million and increased by 13.7% (17.4% at CER). The gross margin was 75.0% and increased by 1.0pp (75.1% at CER, up by 1.1pp). The higher gross margin benefited from overall improved product and country mix in Biopharma and the reducing impact from the loss of exclusivity for Aubagio. In YTD 2024, the gross profit was €25,742 million and increased by 7.0% (11.0% at CER). The gross margin was 74.3% and decreased by 0.5pp (74.7% at CER, down by 0.1pp).
Research and Development expenses were €1,852 million and increased by 11.4% (12.7% at CER). This reflected increased activity in mid- and late-stage development. The ratio of R&D to net sales was 13.8% and decreased by 0.1pp. In YTD 2024, R&D expenses were €5,275 million and increased by 8.6% (10.0% at CER). The ratio of R&D to net sales was 15.2% and increased by 0.1pp.
Selling, general and administrative expenses were €2,681 million and increased by 4.0% (6.4% at CER), substantially less than sales growth. The ratio of SG&A to net sales was 20.0% and decreased by 1.6pp. In YTD 2024, SG&A expenses were €7,941 million and increased by 2.3% (4.7% at CER). The ratio of SG&A to net sales was 22.9% and decreased by 1.2pp.
Total operating expenses were €4,533 million and increased by 6.9% (8.9% at CER). In YTD 2024, total operating expenses were €13,216 million and increased by 4.7% (6.8% at CER).
Other current operating income net of expenses were -€971 million compared to -€598 million in Q3 2023. Other current operating income net of expenses included an expense of €1,066 million from the share of profit to Regeneron from the monoclonal antibody alliance, the share of profit paid by Regeneron towards development costs and the reimbursement of commercialization-related expenses incurred by Regeneron compared to an expense of €889 million in Q3 2023. This line also included €31 million of capital gains from divestments of medicines/portfolio streamlining, compared to €103 million in Q3 2023. Sanofi expects the amount of capital gains from divestments of medicines/portfolio streamlining in Biopharma to be c.€400 million in 2024. In YTD 2024, expenses from the monoclonal antibody alliance with Regeneron were €2,903 million compared to €2,307 million in YTD 2023.
Share of profit from associates was €43 million compared to €20 million in Q3 2023 and included the share of US profit related to Vaxelis. In YTD 2024, share of profit from associates was €118 million compared to €75 million in YTD 2023.
Business operating income5 was €4,607 million and increased by 14.4% (19.9% at CER). The ratio of BOI to net sales was 34.3% and increased by 0.6pp (34.9% at CER, up by 1.2pp). In YTD 2024, BOI was €10,263 million and increased by 1.7% (8.8% at CER). The ratio of BOI to net sales was 29.6% and decreased by 1.8pp (30.7% at CER, down by 0.7pp).
Net financial expenses were €79 million compared to €83 million in Q3 2023. In YTD 2024, net financial expenses were €208 million compared to €132 million in YTD 2023, reflecting increased net debt and higher interest rates.
The effective tax rate increased to 21.0% from 19.0% in Q3 2023 and YTD 2023. Sanofi expects its effective tax rate to be around 20% in 2024 excluding Opella.
Business net income2 was €3,585 million and increased by 12.2% (17.5% at CER). The ratio of business net income to net sales remained stable at 26.7% and increased by 0.4pp at CER. In YTD 2024, business net income was €7,965 million and decreased by 1.3% (increased by 5.5% at CER). The ratio of business net income to net sales was 23.0% and decreased by 2.1pp (1.3pp at CER).
Business earnings per share2 (EPS) was €2.86 and increased by 12.2% on a reported basis (17.6% at CER). The average number of shares outstanding was 1,253.0 million compared to 1,253.2 million in Q3 2023. In YTD 2024, business earnings per share was 6.37 and decreased by 1.2% on a reported basis (increased by 5.6% at CER). The average number of shares outstanding was 1,250.6 million compared to 1,251.0 million in YTD 2023.
Reconciliation of IFRS net income reported to business net income (see Appendix 4)
In YTD 2024, the IFRS net income was €5,061 million. The main items excluded from the business net income were:
•An amortization charge of €1,540 million related to intangible assets measured at their acquisition-date fair values of €1,485 million (mainly Bioverativ €475 million, Provention Bio €160 million, Boehringer Ingelheim consumer healthcare business €134 million, Genzyme €133 million, Ablynx €126 million, Kadmon €122 million, Beyfortus €85 million and Qunol €60 million) and to intangible assets from separate acquisitions, measured initially at acquisition cost (licenses/products) of €55 million. These items had no cash impact.
2 See Appendix 3 for Q3 and YTD 2024 consolidated income statement; see Appendix 7 for definitions of financial indicators, and Appendix 4 for reconciliation of IFRS net
income reported to business net income.
14

•A net reversal of impairment losses of €191 million mainly due to an increase in the expected recoverable amounts of certain marketed products and other rights in the Biopharma segment. The YTD 2024 net reversal is partially offset by €180 million impairment expenses recorded in Q3 2024 mainly related to discontinued research and development projects.
•Restructuring costs and similar items of €1,587 million mainly related to redundancy plans announced during YTD 2024 as well as some separation costs for Opella.
•Other gains and losses, and litigation charge of €452 million mainly comprising a provision recognized in respect of the litigation related to Plavix (clopidogrel) in the US State of Hawaii.
•A financial charge of €229 million related to the remeasurement of expected future royalty on Beyfortus US sales.
•A €911 million tax effect arising from the items listed above, mainly comprising €275 million of deferred taxes generated by amortization of intangible assets and €471 million associated with restructuring costs and similar items (see Appendix 4).
•A loss of €53 million corresponding to the equity investment in EUROAPI.
Capital allocation
In YTD 2024, free cash flow before restructuring, acquisitions and disposals amounted to €5,099 million, after negative change of net working capital (-€2,309 million), notably including the decrease of US rebates provisions (€1,260 million) following the decision to reduce the Lantus list price effective January 1, 2024, and capital expenditures (-€1,378 million). After acquisitions3 (-€710 million), proceeds from disposals4 (€665 million) and payments related to restructuring and similar items (-€1,182 million), free cash flow4 was €3,872 million. After the acquisition of Inhibrx Inc. (-€1,900 million) and the dividend paid by Sanofi (-€4,704 million), net debt increased from €7,793 million on December 31, 2023, to €11,483 million on September 30, 2024 (amount net of €8,243 million cash and cash equivalents).
3 Not exceeding €500 million per transaction (inclusive of all payments related to the transaction).
4 Non-IFRS financial measure (definition in Appendix 7).
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Forward-looking statements
This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, business transformations, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance. Forward-looking statements are generally identified by the words “expects”, “anticipates”, “believes”, “intends”, “estimates”, “plans”, “potential”, “outlook”, “guidance” and similar expressions. Although Sanofi’s management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include among other things, the uncertainties inherent in research and development, future clinical data and analysis, including post marketing, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug, device or biological application that may be filed for any such product candidates as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates, the fact that product candidates if approved may not be commercially successful, the future approval and commercial success of therapeutic alternatives, Sanofi’s ability to benefit from external growth opportunities, to complete capital markets or other transactions and/or obtain regulatory clearances, risks associated with developing standalone businesses, risks associated with intellectual property and any related pending or future litigation and the ultimate outcome of such litigation, trends in exchange rates and prevailing interest rates, volatile economic and capital market conditions, cost containment initiatives and subsequent changes thereto, and the impact that pandemics, political disruption or armed conflicts or other global crises may have on us, our customers, suppliers, vendors, and other business partners, and the financial condition of any one of them, as well as on our employees and on the global economy as a whole. The risks and uncertainties also include the uncertainties discussed or identified in the public filings with the SEC and the AMF made by Sanofi, including those listed under “Risk Factors” and “Cautionary Statement Regarding Forward-Looking Statements” in Sanofi’s annual report on Form 20-F for the year ended December 31, 2023. Other than as required by applicable law, Sanofi does not undertake any obligation to update or revise any forward-looking information or statements. All Sanofi trademarks mentioned in this document are protected.
Appendices

Media Relations
Sandrine Guendoul | + 33 6 25 09 14 25 | sandrine.guendoul@sanofi.com
Evan Berland | + 1 215 432 0234 | evan.berland@sanofi.com
Nicolas Obrist | + 33 6 77 21 27 55 | nicolas.obrist@sanofi.com
Léo Le Bourhis | + 33 6 75 06 43 81 | leo.lebourhis@sanofi.com
Victor Rouault | + 33 6 70 93 71 40 | victor.rouault@sanofi.com
Timothy Gilbert | + 1 516 521 2929 | timothy.gilbert@sanofi.com

Investor Relations
Thomas Kudsk Larsen | + 44 7545 513 693 | thomas.larsen@sanofi.com
Alizé Kaisserian | + 33 6 47 04 12 11 | alize.kaisserian@sanofi.com
Arnaud Delépine | + 33 6 73 69 36 93 | arnaud.delepine@sanofi.com
Felix Lauscher | + 1 908 612 7239 | felix.lauscher@sanofi.com
Keita Browne | + 1 781 249 1766 | keita.browne@sanofi.com
Nathalie Pham | + 33 7 85 93 30 17 | nathalie.pham@sanofi.com
Tarik Elgoutni | + 1 617 710 3587 | tarik.elgoutni@sanofi.com
Thibaud Châtelet | + 33 6 80 80 89 90 | thibaud.chatelet2@sanofi.com
16

Appendix 1: Q3 2024 net sales by medicine/vaccine/business and geographic region
Q3 2024 (€ million)Total Sales% CER% reported United States% CER Europe% CER Rest of World% CER
Immunology
Dupixent3,476 +23.8 %+22.1 %2,556 +19.1 %417 +35.1 %503 +41.9 %
Kevzara109 +28.7 %+25.3 %65 +40.4 %30 — %14 +60.0 %
Rare diseases
Fabrazyme253 +4.0 %— %131 +7.3 %62 +5.1 %60 -2.8 %
ALTUVIIIO (*)172 +278.3 %+273.9 %160 +250.0 %— — %12 — %
Myozyme168 -7.5 %-10.2 %63 +4.9 %60 -26.5 %45 +11.6 %
Cerezyme164 +8.0 %-6.8 %47 — %55 — %62 +18.9 %
Nexviazyme/Nexviadyme (*)163 +53.6 %+48.2 %90 +24.7 %47 +104.3 %26 +121.4 %
Alprolix148 +8.7 %+7.2 %110 -2.6 %— — %38 +62.5 %
Eloctate96 -19.2 %-20.0 %56 -37.1 %— — %40 +32.3 %
Cerdelga81 +12.3 %+11.0 %46 +17.9 %31 +6.9 %4 — %
Aldurazyme67 +4.5 %— %18 +12.5 %18 -10.5 %31 +9.4 %
Cablivi (*)63 +12.5 %+12.5 %34 +34.6 %24 — %5 -33.3 %
Xenpozyme (*)41 +51.9 %+51.9 %20 +42.9 %14 +40.0 %7 +133.3 %
Enjaymo (*)28 +81.3 %+75.0 %17 +70.0 %4 +300.0 %7 +60.0 %
Neurology
Aubagio92 -52.3 %-53.8 %49 -27.5 %30 -74.6 %13 +25.0 %
Oncology
Sarclisa (*)114 +23.7 %+17.5 %46 +4.5 %34 +22.2 %34 +57.7 %
Jevtana72 +10.4 %+7.5 %56 +21.3 %1 -50.0 %15 -11.1 %
Fasturtec46 +15.0 %+15.0 %29 +11.5 %13 +20.0 %4 +25.0 %
Other Pharma
Lantus431 +33.8 %+25.7 %175 +162.7 %85 +2.4 %171 +2.6 %
Toujeo303 +18.1 %+14.3 %54 +14.6 %118 +6.3 %131 +32.1 %
Lovenox233 -1.2 %-8.6 %1 — %131 -8.4 %101 +8.1 %
Plavix230 +8.3 %+5.5 %2 — %23 -4.2 %205 +9.9 %
Rezurock (*)131 +57.8 %+57.8 %118 +48.8 %8 +700.0 %5 +100.0 %
Praluent126 +10.4 %+9.6 %— — %85 +14.9 %41 +2.4 %
Thymoglobulin121 +4.1 %-1.6 %73 +1.4 %10 +11.1 %38 +7.3 %
Aprovel98 +1.0 %+1.0 %1 -100.0 %18 — %79 +6.7 %
Multaq72 -21.5 %-22.6 %65 -23.5 %2 — %5 — %
Soliqua/iGlarLixi55 +12.0 %+10.0 %17 -18.2 %12 +44.4 %26 +31.6 %
Mozobil16 -70.6 %-68.6 %4 -85.2 %7 -58.8 %5 -42.9 %
Tzield (*)15 +66.7 %+66.7 %15 +66.7 %— — %— — %
Others 1,055 -6.5 %-11.1 %94 -16.5 %296 -5.7 %665 -5.3 %
Industrial Sales126 +0.8 %— %1 — %125 +6.8 %— -100.0 %
Total Pharma8,365 +13.0 %+9.8 %4,213 +18.4 %1,760 +2.2 %2,392 +12.7 %
Influenza vaccines
1,913 +10.9 %+8.3 %1,239 +9.0 %480 +20.1 %194 +3.9 %
Polio/Pertussis/Hib vaccines & Boosters
760 +2.0 %-0.3 %225 +8.5 %133 -2.9 %402 +0.2 %
RSV (Beyfortus) (**)
645 +381.8 %+370.8 %532 +494.6 %98 +117.8 %15 — %
Meningitis, Travel and endemic vaccines
485 +13.1 %+11.8 %334 +10.4 %51 +25.0 %100 +17.4 %
Vaccines3,802 +25.5 %+22.7 %2,331 +34.4 %762 +22.4 %709 +5.8 %
Biopharma12,167 +16.6 %+13.5 %6,544 +23.7 %2,522 +7.6 %3,101 +11.1 %
Opella1,271 +7.9 %+2.1 %342 +21.8 %364 +0.3 %565 +5.9 %
Company13,438 +15.7 %+12.3 %6,886 +23.6 %2,886 +6.6 %3,666 +10.3 %
New Pharma launches (*)
727 +67.1 %+63.7 %500 +66.9 %131 +51.2 %96 +92.9 %
New launches (*), (**)
1,372+141.3%+136.1%1,032 +166.8%229 +74.0%111 +119.6%
17

Appendix 1: YTD 2024 net sales by medicine/vaccine and geographic region
YTD 2024 (€ million)Total Sales% CER% reported United States% CER Europe% CER Rest of World% CER
Immunology
Dupixent9,614 +25.9 %+24.5 %6,993 +19.9 %1,187 +32.5 %1,434 +55.5 %
Kevzara298 +21.0 %+18.3 %170 +26.9 %89 +6.0 %39 +35.3 %
Rare diseases
Fabrazyme779 +8.0 %+4.0 %392 +5.1 %191 +5.5 %196 +16.0 %
ALTUVIIIO (*)452 +600.0 %+595.4 %419 +566.7 %— — %33 +1650.0 %
Myozyme539 -11.1 %-13.5 %185 -5.1 %205 -22.3 %149 — %
Cerezyme571 +17.0 %+3.3 %143 +1.4 %181 +3.4 %247 +36.3 %
Nexviazyme/Nexviadyme (*)483 +69.7 %+64.3 %264 +35.2 %142 +118.5 %77 +178.8 %
Alprolix419 +6.3 %+5.3 %335 +2.1 %— — %84 +26.1 %
Eloctate287 -20.7 %-22.0 %183 -32.7 %— — %104 +13.5 %
Cerdelga246 +11.7 %+10.3 %136 +11.5 %96 +9.1 %14 +30.8 %
Aldurazyme228 +11.1 %+5.1 %54 +8.0 %63 +1.6 %111 +17.9 %
Cablivi (*)176 +4.7 %+4.1 %94 +13.1 %67 -8.2 %15 +25.0 %
Xenpozyme (*)113 +75.4 %+73.8 %57 +62.9 %38 +52.0 %18 +280.0 %
Enjaymo (*)83 +75.5 %+69.4 %47 +62.1 %14 +180.0 %22 +66.7 %
Neurology
Aubagio301 -62.8 %-63.9 %145 -65.0 %125 -65.9 %31 -22.0 %
Oncology
Sarclisa (*)341 +29.5 %+22.7 %146 +21.7 %98 +16.9 %97 +56.0 %
Jevtana213 -10.3 %-12.3 %156 -10.3 %5 -50.0 %52 -3.4 %
Fasturtec132 +2.3 %+1.5 %85 +1.2 %36 +6.1 %11 — %
Other Pharma
Lantus1,189 +10.6 %+4.0 %445 +80.6 %260 -5.1 %484 -10.3 %
Toujeo937 +15.6 %+10.9 %171 +3.6 %359 +8.1 %407 +28.5 %
Lovenox751 -7.1 %-12.9 %7 +16.7 %436 -7.8 %308 -6.5 %
Plavix703 +5.6 %+1.3 %5 -16.7 %69 -4.2 %629 +7.0 %
Rezurock (*)338 +50.9 %+50.9 %306 +39.5 %20 +566.7 %12 +1000.0 %
Praluent373 +23.7 %+22.7 %— -100.0 %255 +18.1 %118 +36.0 %
Thymoglobulin367 +4.9 %+0.3 %230 +4.1 %29 +3.6 %108 +6.9 %
Aprovel311 +1.6 %— %3 -71.4 %55 -5.2 %253 +5.3 %
Multaq234 -8.6 %-8.9 %210 -9.5 %8 -11.1 %16 +6.3 %
Soliqua/iGlarLixi169 +11.5 %+8.3 %55 -16.4 %35 +38.5 %79 +30.2 %
Mozobil62 -66.8 %-66.8 %9 -91.9 %35 -34.0 %18 -21.7 %
Tzield (*)36 +140.0 %+140.0 %35 +133.3 %1 — %— — %
Others 3,275 -6.9 %-11.3 %279 -14.6 %954 -5.9 %2,042 -6.3 %
Industrial Sales404 -0.2 %-0.5 %4 -20.0 %399 +4.7 %1 -90.0 %
Total Pharma24,424 +10.7 %+7.6 %11,763 +14.5 %5,452 +1.9 %7,209 +11.9 %
Influenza vaccines
2,101 +12.3 %+9.0 %1,255 +8.6 %510 +16.7 %336 +20.0 %
Polio/Pertussis/Hib vaccines & Boosters
2,108 -1.2 %-3.7 %536 -3.4 %381 +3.5 %1,191 -1.7 %
RSV (Beyfortus) (**)
845 +537.2 %+516.8 %648 +621.7 %105 +133.3 %92 — %
Meningitis, Travel and endemic vaccines
1,067 +7.9 %+6.4 %635 +6.8 %148 +31.3 %284 +1.0 %
Vaccines6,121 +14.5 %+11.5 %3,075 +28.6 %1,144 -4.1 %1,902 +8.0 %
Biopharma30,545 +11.5 %+8.4 %14,838 +17.2 %6,596 +0.8 %9,111 +11.1 %
Opella4,102 +8.8 %+3.5 %1,115 +23.6 %1,172 -2.7 %1,815 +9.1 %
Company34,647 +11.1 %+7.8 %15,953 +17.6 %7,768 +0.2 %10,926 +10.8 %
New Pharma launches (*)2,02278.2 %74.5 %1,36880.1 %38049.2 %274+119.6 %
New launches (*), (**)2,867 +126.7 %+121.2 %2,016 +138.4 %485 +61.9 %366 +192.3 %
18

Appendix 2: Business net income statement
Q3 2024BiopharmaOpella
Consumer Healthcare		OtherTotal group
€ millionQ3 2024Q3 2023ChangeQ3 2024Q3 2023ChangeQ3 2024Q3 2023ChangeQ3 2024Q3 2023Change
Net sales12,167 10,719 13.5 %1,271 1,245 2.1 %— — — %13,438 11,964 12.3 %
Other revenues704723-2.6%151136.4%———%719734-2.0%
Cost of Sales(3,564)(3,344)6.6%(517)(502)3.0%(2)6-133.3%(4,083)(3,840)6.3%
As % of net sales(29.3%)(31.2%)(40.7%)(40.3%)(30.4%)(32.1%)
Gross profit9,307 8,098 14.9 %769 754 2.0 %(2)6 -133.3 %10,074 8,858 13.7 %
As % of net sales76.5%75.5%60.5%60.6%75.0%74.0%
Research and development expenses(1,806)(1,611)12.1%(46)(52)-11.5%———%(1,852)(1,663)11.4%
As % of net sales(14.8%)(15.0%)(3.6%)(4.2%)(13.8%)(13.9%)
Selling and general expenses(2,223)(2,160)2.9%(456)(419)8.8%(2)——%(2,681)(2,579)4.0%
As % of net sales(18.3%)(20.2%)(35.9%)(33.7%)(20.0%)(21.6%)
Other current operating income/expenses(973)(585)18(3)(16)(10)(971)(598)
Share of profit/loss of associates* and joint ventures381159——4320
Net income attributable to non-controlling interests(3)(5)(3)(5)——(6)(10)
Business operating income4,340 3,748 15.8 %287 284 1.1 %(20)(4)400.0 %4,607 4,028 14.4 %
As % of net sales35.7%35.0%22.6%22.8%34.3%33.7%
Financial income and expenses(79)(83)
Income tax expenses(943)(749)
Tax rate**21.0%19.0%
Business net income3,585 3,196 12.2 %
As % of net sales26.7%26.7%
Business earnings / share(in euros)***2.862.5512.2 %
* Net of tax.
** Determined on the basis of Business income before tax, associates, and non-controlling interests.
*** Based on an average number of shares outstanding of 1,253.0 million in the third quarter of 2024 and 1,253.2 million in the third quarter of 2023.
19

YTD 2024BiopharmaOpella
Consumer Healthcare		OtherTotal group
€ millionYTD 2024YTD 2023ChangeYTD 2024YTD 2023ChangeYTD 2024YTD 2023ChangeYTD 2024YTD 2023Change
Net sales30,545 28,186 8.4 %4,102 3,965 3.5 %— — — %34,647 32,151 7.8 %
Other revenues1,9612,054-4.5%473823.7%———%2,0082,092-4.0%
Cost of Sales(9,320)(8,732)6.7%(1,594)(1,451)9.9%11—%(10,913)(10,182)7.2%
As % of net sales(30.5%)(31.0%)(38.9%)(36.6%)(31.5%)(31.7%)
Gross profit23,186 21,508 7.8 %2,555 2,552 0.1 %1 1 — %25,742 24,061 7.0 %
As % of net sales75.9%76.3%62.3%64.4%74.3%74.8%
Research and development expenses(5,137)(4,693)9.5%(138)(163)-15.3%———%(5,275)(4,856)8.6%
As % of net sales(16.8%)(16.7%)(3.4%)(4.1%)(15.2%)(15.1%)
Selling and general expenses(6,483)(6,408)1.2%(1,458)(1,355)7.6%—2-100.0%(7,941)(7,761)2.3%
As % of net sales(21.2%)(22.7%)(35.5%)(34.2%)(22.9%)(24.1%)
Other current operating income/expenses(2,390)(1,482)6197(35)(18)(2,364)(1,403)
Share of profit/loss of associates* and joint ventures 104591416——11875
Net income attributable to non-controlling interests(9)(16)(8)(13)——(17)(29)
Business operating income 9,271 8,968 3.4 %1,026 1,134 -9.5 %(34)(15)126.7 %10,263 10,087 1.7 %
As % of net sales30.4%31.8%25.0%28.6%29.6%31.4%
Financial income and expenses(208)(132)
Income tax expenses(2,090)(1,883)
Tax rate**21.0%19.0%
Business net income7,965 8,072 -1.3 %
As % of net sales23.0%25.1%
Business earnings / share(in euros)***6.376.45-1.2 %
* Net of tax.    
** Determined on the basis of Business income before tax, associates, and non-controlling interests.
*** Based on an average number of shares outstanding of 1,250.6 million in YTD 2024 and 1,251.0 million in YTD 2023.
20

Appendix 3: Consolidated income statements
€ millionQ3 2024Q3 2023YTD 2024YTD 2023
Net sales13,438 11,964 34,647 32,151 
Other revenues719 734 2,008 2,092 
Cost of sales(4,085)(3,841)(10,934)(10,188)
Gross profit10,072 8,857 25,721 24,055 
Research and development expenses(1,852)(1,663)(5,275)(4,856)
Selling and general expenses(2,681)(2,579)(7,941)(7,761)
Other operating income187 388 804 1,005 
Other operating expenses(1,158)(986)(3,168)(2,408)
Amortization of intangible assets(479)(562)(1,540)(1,597)
Impairment of intangible assets
(180)(4)191 (19)
Fair value remeasurement of contingent consideration(8)(3)(74)(29)
Restructuring costs and similar items(256)(259)(1,587)(806)
Other gains and losses, and litigation
(10)22 (452)(51)
Operating income3,635 3,211 6,679 7,533 
Financial expenses(265)(318)(851)(688)
Financial income133 143 414 429 
Income before tax and associates and joint ventures3,503 3,036 6,242 7,274 
Income tax expense(737)(563)(1,200)(1,293)
Share of profit/(loss) of associates and joint ventures78 65 65 13 
Net income2,844 2,538 5,107 5,994 
Net income attributable to non-controlling interests29 13 46 39 
Net income attributable to equity holders of Sanofi2,815 2,525 5,061 5,955 
Average number of shares outstanding (million)1,253.0 1,253.2 1,250.6 1,251.0 
IFRS Earnings per share (in euros)2.25 2.01 4.05 4.76 
21

Appendix 4: Reconciliation of net income attributable to equity holders of Sanofi to business net income
€ millionQ3 2024Q3 2023YTD 2024YTD 2023
Net income attributable to equity holders of Sanofi2,815 2,525 5,061 5,955 
Amortization of intangible assets (1)
479 562 1,540 1,597 
Impairment of intangible assets
180 4 (191)19 
Fair value remeasurement of contingent consideration31 6 103 39 
Expenses arising from the impact of acquisitions on inventories2 1 21 6 
Restructuring costs and similar items256 259 1,587 806 
Other gains and losses, and litigation
10 (22)452 51 
Financial (income) / expense related to liabilities carried at amortized cost other than net indebtedness53 92 229 127 
Tax effect of the items listed above:(220)(192)(911)(607)
Amortization and impairment of intangible assets(125)(101)(221)(327)
Fair value remeasurement of contingent consideration(2)(2)(19)(8)
Expenses arising from the impact of acquisitions on inventories— — (3)— 
Restructuring costs and similar items(63)(73)(471)(230)
Other items(30)(16)(197)(42)
Other tax effects14 6 21 17 
Other items(35)(45)53 62 
Business net income3,585 3,196 7,965 8,072 
IFRS earnings per share (2) (in euros)
2.25 2.01 4.05 4.76 
1 Of which related to amortization expense generated by the intangible assets measured at their acquisition-date fair values: €462 million in the third quarter of 2024 and
€540 million in the third quarter of 2023.
2 Q3: based on an average number of shares outstanding of 1,253.0 million in the third quarter of 2024 and 1,253.2 million in the third quarter of 2023.
YTD: based on an average number of shares outstanding of 1,250.6 million in YTD 2024 and 1,251.0 million in YTD 2023.
22

Appendix 5: Change in net debt
€ millionYTD 2024YTD 2023
Business net income7,965 8,072 
Depreciation, amortization and impairment of property, plant and equipment and software1,196 1,163 
Other items(375)(591)
Operating cash flow8,786 8,644 
Changes in Working Capital(2,309)(1,674)
Acquisitions of property, plant and equipment and software(1,378)(1,257)
Free cash flow before restructuring, acquisitions and disposals5,099 5,713 
Acquisitions of intangibles assets, investments and other long-term financial assets (1)
(710)(667)
Restructuring costs and similar items paid(1,182)(884)
Proceeds from disposals of property, plant and equipment, intangible assets and other non-current assets net of taxes (1)
665 820 
Free cash flow3,872 4,982 
Acquisitions (2)
(2,507)(3,915)
Issuance of Sanofi shares180 187 
Acquisition of treasury shares(302)(363)
Dividends paid to shareholders of Sanofi(4,704)(4,454)
Other items(229)(577)
Change in net debt(3,690)(4,140)
Beginning of period7,793 6,437 
Closing of net debt11,483 10,577 
1 Free cash flow includes investments and divestments not exceeding a cap of €500 million per transaction (inclusive of all payments related to the transaction).
2 Includes transactions that are above a cap of €500 million per transaction (inclusive of all payments related to the transaction).
23

Appendix 6: Currency sensitivity
2024 business EPS currency sensitivity
CurrencyVariationBusiness EPS Sensitivity
US Dollar+0.05 USD/EUR -EUR 0.17
Japanese Yen+5 JPY/EUR -EUR 0.02
Chinese Yuan+0.2 CNY/EUR -EUR 0.02
Brazilian Real+0.4 BRL/EUR -EUR 0.01
Russian Ruble+10 RUB/EUR -EUR 0.01
Currency exposure on Q3 2024 sales
CurrencyQ3 2024
US Dollar52.5 %
Euro18.6 %
Chinese Yuan5.3 %
Japanese Yen3.0 %
Mexican pesos1.9 %
Brazilian Real1.7 %
Canadian Dollar1.4 %
British Pound1.1 %
South Korean won1.0 %
Australian Dollar0.9 %
Others12.6 %
Currency average rates
Q3 2023Q3 2024Change
€/$1.088 1.099 +1.0 %
€/Yen157.211 163.727 +4.1%
€/Yuan7.896 7.876 -0.2 %
€/Real5.311 6.095 +14.7%
€/Ruble102.548 98.161 -4.3 %
24

Appendix 7: Definitions of non-IFRS financial indicators
Company sales at constant exchange rates (CER)
References to changes in net sales “at constant exchange rates” (CER) means that it excludes the effect of changes in exchange rates.
The effect of exchange rates are eliminated by recalculating net sales for the relevant period at the exchange rates used for the previous period.
Reconciliation of net sales to company sales at constant exchange rates for Q3 and YTD 2024
€ millionQ3 2024YTD 2024
Net sales13,43834,647 
Effect of exchange rates(406)(1,088)
Company sales at constant exchange rates13,844 35,735 
Business net income
Sanofi publishes a key non-IFRS indicator. Business net income is defined as net income attributable to equity holders of Sanofi excluding:
•amortization of intangible assets,
•impairment of intangible assets,
•fair value remeasurement of contingent consideration related to business combinations or to disposals,
•expenses arising from the impact of acquisitions on inventories
•restructuring costs and similar items(1),
•other gains and losses (including gains and losses on disposals of non-current assets(1)),
•costs or provisions associated with litigation(1),
•financial (income)/expense related to liabilities carried at amortized cost other than net indebtedness,
•tax effects related to the items listed above as well as effects of major tax disputes,
•the share of profits/losses from investments accounted for using the equity method, except for joint ventures and associates with which Sanofi has a strategic alliance,
•net income attributable to non-controlling interests related to the items listed above.
1 Reported in the line items Restructuring costs and similar items and Gains and losses on disposals, and litigation, which are defined in Notes B.16. and B.17. to the
consolidated financial statements.
Free cash flow
Free cash flow is a non-IFRS financial indicator which is reviewed by management, and which management believes provides useful information to measure the net cash generated from Sanofi’s operations that is available for strategic investments1 (net of divestments1), for debt repayment, and for capital return to shareholders. Free cash flow is determined from the Business net income adjusted for depreciation, amortization and impairment, share of profit/loss in associates and joint ventures net of dividends received, gains and losses on disposals, net change in provisions including pensions and other post-employment benefits, deferred taxes, share-based expense and other non-cash items. It comprises net changes in working capital, capital expenditures and other asset acquisitions2 net of disposal proceeds2, and payments related to restructuring and similar items. Free cash flow is not defined by IFRS and it is not a substitute measure for the IFRS aggregate net cash flows in operating activities.
1 Amount of the transaction above a cap of €500 million per transaction (inclusive of all payments related to the transaction).
2 Not exceeding a cap of €500 million per transaction (inclusive of all payments related to the transaction).
25

Appendix 8: CSR dashboards
Data are presented in YTD unless stated otherwise.
TopicAmbitionProgress
Affordable access Q3 2024Q2 2024
Sanofi global health
Reach 1.5 million non-communicable disease patients by 2026 (cumulative since 2022) and 2 million by 2030
285,563 patients treated in 28 countries

67 active healthcare partnerships in 39 countries

7 investments signed through the Impact Fund		127,746 patients treated in 24 countries

46 active healthcare partnerships in 21 countries

4 investments signed through the Impact Fund
Vials donationsDonate 100,000 vials a year to treat people with rare diseases, via the Humanitarian Program launched by Sanofi Specialty Care1,198 patients treated
83,341 vials donated		1,164 patients treated
46,124 vials donated
Global access plansDevelop a global access plan for all new medicines/vaccines to make them available within two years after first launch11 global access plans initiated or developed covering more than 15 indications10 global access plans initiated or developed covering more than 14 indications
R&D for unmet needsFY 2023FY 2022
Sleeping sickness
Develop and supply innovative treatments to support the elimination of sleeping sickness by 2030 (annual update)

2.4 million patients tested
699 patients treated		1.5 million patients tested
837 patients treated
Q3 2024Q2 2024
Polio
Provide inactivated polio vaccines (IPV) to UNICEF for GAVI countries to support polio eradication efforts
27.8 million IPV doses supplied to UNICEF for GAVI countries16.2 million IPV doses supplied to UNICEF for GAVI countries
Pediatric cancer treatment development
Develop innovative treatments to eliminate cancer death in children3 projects undergoing preclinical assessment

1 project in clinical study

8 partnerships on scientific projects and engagement

2 external publications		3 projects undergoing preclinical assessment

1 project in clinical study

8 partnerships on scientific projects and engagement
Planet careQ3 2024Q2 2024
Climate change – carbon footprint
(CO2 emissions)
55% reduction in scope 1&2 greenhouse gas emissions (CO2 equivalent) by 2030 (cumulative vs 2019 baseline) to contribute to carbon neutrality by 2030 and net zero emissions by 2045 (all scopes)
44% GHG reduction vs 201943% GHG reduction vs 2019
Renewable electricity
100% of renewable electricity in all sites by 2030
85%85%
Eco-car fleet100% eco-car fleet in 2030
50% eco-car fleet 48% eco-car fleet
Blister-free syringe vaccines100% blister-free syringe vaccines by 2027Data updated annually, next update in Q4 2024
Eco-designAll new medicines/vaccines to be eco-designed by 2025

27 life-cycle assessments completed (new and marketed medicines/vaccines)
17 life-cycle assessments completed (new and
marketed medicines/vaccines)
In and beyond the workplace
Q3 2024Q2 2024
Global gender balanceAmbition of 50% of women in senior leadership roles by 202545%45%
Ambition of 40% of women in executive roles by 202542%42%
Engagement with communitiesEngage socially and economically with all communities with operationsNext update in Q4 20242,732 volunteers
25,945 hours
From leaders to citizens100% of leaders have CSR in their development path77% of leaders have completed the e-learning phase

34% of leaders have completed the full program		77% of leaders have completed the e-learning phase

33% of leaders have completed the full program
End.
26
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