WASHINGTON, Dec. 9, 2019 /PRNewswire/ -- At the 2019 joint
meeting of the American Society for Cell Biology (ASCB) and
European Molecular Biology Organization (EMBO), Bruker (Nasdaq:
BRKR) today announced the launch of the Luxendo TruLive3D
Imager light-sheet imaging system. The new
system features dual-sided illumination and highly efficient light
collection for fast imaging of a broad range of biological samples
in their native 3D environments. The TruLive3D Imager
leverages the general benefits of single-plane illumination
microscopy (SPIM) to enable rapid 3D imaging with minimal light
exposure, confocal resolution and excellent contrast in 3D. An
extended sample chamber enables multi-sample experiments and an
integrated environmental chamber ensures long-term live
observations of even the most delicate samples such as stem cells,
primary human cells and organoids.
"Our primary breast cancer mouse model allows us to specifically
induce and control cancer initiation and progression in 3D
organoids," said Dr. Martin Jechlinger, Group Leader at the
European Molecular Biology Laboratory (EMBL) in Heidelberg,
Germany, the first researcher to
test the TruLive3D Imager. "We have been using
light-sheet imaging successfully in the past and the new Luxendo
system allows us to scale our experiments to hundreds of organoids
per imaging session and marks a quantum leap for our research."
"Life happens in 3D," added Dr. Lars Hufnagel, Vice President and General
Manager of Bruker's Luxendo business. "Our new
TruLive3D Imager now enables imaging
biology in its native environment without compromising resolution
and imaging speed or worrying about photo-toxicity."
About Luxendo
TruLive3D Imager
The
Luxendo TruLive3D Imager system
maintains the ease of use and stability of the InVi
SPIM and is optimized to allow fast 3D
multi-sample imaging of live specimens. The optical concept, with
dual-sided illumination and single-lens detection from below,
enables fast acquisition, high-resolution imaging, and minimal
shadowing effects, while a wide-field imaging option
facilitates sample positioning. The large sample chamber (75 mm in
length) can accommodate up to 100 samples into the chamber trough
and is ideal for multi-position imaging of small embryos (e.g.,
Zebrafish, Drosophila, and mouse) or 3D spheroids. For example,
time-lapse embryo imaging experiments can benefit hugely from the
TruLive3D Imager design and
performance.
To facilitate sample mounting for inverted light-sheet
microscopes (InVi SPIM and TruLive3D
Imager), Luxendo's new TruLive3D
Dish series is optimized for light-sheet
imaging of cells, 3D cell culture systems, organoids, and small
animals. The sterile, dual-well dishes are ready to use and
customizable, and samples can be grown or placed into holders as
with standard petri dishes. The new dishes also seamlessly
integrate into the large chamber of the TruLive3D
Imager, which can fit up to three dishes to maximize
throughput.
About Bruker Corporation (Nasdaq: BRKR)
Bruker
is enabling scientists to make breakthrough discoveries and develop
new applications that improve the quality of human life. Bruker's
high-performance scientific instruments and high-value analytical
and diagnostic solutions enable scientists to explore life and
materials at molecular, cellular and microscopic levels. In close
cooperation with our customers, Bruker is enabling innovation,
improved productivity and customer success in life science
molecular research, in applied and pharma applications, in
microscopy and nanoanalysis, and in industrial applications, as
well as in cell biology, preclinical imaging, clinical phenomics
and proteomics research and clinical microbiology. For more
information, please visit: www.bruker.com.
Investor Contact:
Miroslava
Minkova
Director, Investor Relations & Corporate Development
Bruker Corporation
T: +1 (978) 663-3660 x1479
E: Investor.Relations@bruker.com
Media Contact:
Carolina Araya Callís
Luxendo Marketing
T: +49 6221 187 3150
E: carolina.araya@bruker.com
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SOURCE Bruker Corporation