The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

  UNITED STATES SECURITIES AND EXCHANGE COMMISSION OMB APPROVAL
 Washington, D.C. 20549
FORM 13F		OMB Number:   3235-0006
Expires:          July 31, 2015
Estimated average burden
hours per response:       23.8


FORM 13F COVER PAGE


Report for the Calendar Year or Quarter Ended:
03-31-2023
 
Check here if Amendment:      Amendment Number:
 
This Amendment (Check only one.):    is a restatement.
     adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:JANUS HENDERSON GROUP PLC 
Address:201 BISHOPSGATE 
 LONDON X0 EC2M 3AE 

Form 13F File Number:  028-10904 
CRD Number (if applicable):   
SEC File Number (if applicable):   


The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report on Behalf of Reporting Manager:

Name:Kristin Mariani 
Title:Head of North America Compliance 
Phone: 303-333-3863 

Signature, Place, and Date of Signing:

/s/ Kristin Mariani Denver,  COLORADO 05-15-2023 
[Signature][City, State][Date]

Do you wish to provide information pursuant to Special Instruction 5?        Yes      X  No

Report Type (Check only one.):

     13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.)

     13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).)

X  13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)


List of Other Managers Reporting for this Manager
[If there are no entries in this list, omit this section.]

NameForm 13F File No.CRD No. (if applicable)SEC File No. (if applicable)
INTECH INVESTMENT MANAGEMENT LLC 028-04211 000119232 801-60987 

Form 13F Summary Page

Report Summary:

Number of Other Included Managers:15 
Form 13F Information table Entry Total:6718 
Form 13F Information table Value Total:151,663,570,997 
 (round to nearest dollar)

List of Other Included Managers:

Provide a numbered list of the name(s) and Form 13F number(s) of all institutional investement managers with respect to which this report is filed, other than the manager filing this report.

   No.NameForm 13F File NumberCRD No. (if applicable)SEC File No. (if applicable)CIK
39 FIRST TRUST ADVISORS LP 028-06487 000107027 801-39950 0001125816 
10 JANUS HENDERSON INVESTORS US LLC 028-01343 000104652 801-13991 0000812295 
11 Janus Henderson Investors (Australia) Institutional Funds Management Ltd 028-20157   0001794678 
12 Janus Henderson Investors (Singapore) Ltd 028-20257   0001810753 
16 Janus Henderson Investors (Jersey) Ltd 028-21345   0001874815 
30 Equitable Investment Management Group, LLC 028-14633 000156933 801-72220 0001536185 
31 Park Avenue Institutional Advisers LLC 028-16979 000175101 801-81084 0001640801 
32 GuideStone Capital Management, LLC 028-10998 000112319 801-60303 0001308668 
33 NEW YORK LIFE INVESTMENT MANAGEMENT LLC 028-06325 000109591 801-57396 0001133639 
34 Nationwide Fund Advisors 028-05161 000109391 801-56370 0001097218 
35 NORTHERN TRUST CORP 028-00290 000007927 801-80781 0000073124 
36 Pacific Life Fund Advisors LLC 028-14003 000105169 801-15057 0001499091 
37 Penn Mutual Asset Management, LLC 028-18923 000107518 801-35477 0000855702 
38 SEI INVESTMENTS MANAGEMENT CORP 028-16475 000105146 801-24593 0000907692 
4 JANUS HENDERSON INVESTORS UK Ltd 028-10906   0001280110 
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