which power resides with the Fidelity Funds’ Boards of Trustees. FMR Co. carries out the voting of the shares under written guidelines established by the Fidelity Funds’ Boards of Trustees. The address for FMR LLC is 245 Summer Street, Boston, MA 02210.
(3)
This information is based solely upon Amendment No. 5 to Schedule 13G/A filed with the SEC by Biotechnology Value Fund, L.P. (“BVF”) on February 14, 2022. Consists of (i) 2,061,457 shares held by BVF, (ii) 1,353,910 shares held by Biotechnology Value Fund II, L.P. (“BVF2”), (iii) 195,037 shares held by Biotechnology Value Trading Fund OS LP (“Trading Fund OS”), (iv) 41,355 shares held in the Partners Managed Accounts, (v) 625,001 shares underlying certain Class A Warrants, (vi) 624,999 shares underlying certain Class B Warrants and (vii) 82,000 shares underlying certain pre-funded warrants with an exercise price of $0.00001 per share (“New Warrants”). Excludes an estimated 318,000 shares issuable upon the exercise of an estimated 318,000 New Warrants, the exercise of which is subject to a beneficial ownership limitation of 9.99% of the outstanding common stock. BVF I GP LLC (“BVF GP”), as the general partner of BVF, may be deemed to beneficially own the shares beneficially owned by BVF. BVF II GP LLC (“BVF2 GP”), as the general partner of BVF2, may be deemed to beneficially own the shares beneficially owned by BVF2. BVF Partners OS Ltd. (“Partners OS”), as the general partner of Trading Fund OS, may be deemed to beneficially own the shares beneficially owned by Trading Fund OS. BVF GP Holdings LLC (“BVF GPH”), as the sole member of each of BVF GP and BVF2 GP, may be deemed to beneficially own the shares beneficially owned in the aggregate by BVF and BVF2. BVF Partners L.P. (“Partners”), as the investment manager of BVF, BVF2 and Trading Fund OS, and the sole member of Partners OS, may be deemed to beneficially own the shares beneficially owned in the aggregate by BVF, BVF2 and Trading Fund OS, and the shares held in the Partners Managed Accounts. BVF Inc., as the general partner of Partners, may be deemed to beneficially own the shares beneficially owned by Partners. Mark N. Lampert, as a director and officer of BVF Inc., may be deemed to beneficially own the shares beneficially owned by BVF Inc. BVF GP disclaims beneficial ownership of the shares beneficially owned by BVF. BVF2 GP disclaims beneficial ownership of the shares beneficially owned by BVF2. Partners OS disclaims beneficial ownership of the shares beneficially owned by Trading Fund OS. BVF GPH disclaims beneficial ownership of the shares beneficially owned by BVF and BVF2. Each of Partners, BVF Inc. and Mr. Lampert disclaims beneficial ownership of the shares beneficially owned by BVF, BVF2 and Trading Fund OS and held in the Partners Managed Accounts. The address for BVF, BVF GP, BVF2, BVF2 GP, BVF GPH, Partners, BVF Inc. and Mark N. Lampert is 44 Montgomery Street, 40th Floor, San Francisco, CA 94104. The address of Trading Fund OS and Partners OS is PO Box 309 Ugland House, Grand Cayman, KY1-1104, Cayman Islands.
(4)
This information is based solely upon Amendment No. 4 to Schedule 13G/A jointly filed with the SEC on February 11, 2022 by the following entities and persons: (i) Farallon Partners, L.L.C. (“Farallon General Partner”); (ii) Farallon Institutional (GP) V, L.L.C. (“FCIP V General Partner”); (iii) Farallon F5 (GP), L.L.C. (“F5MI General Partner”); (iv) Farallon Healthcare Partners (GP), L.L.C. (“FHPM General Partner”); and (v) Philip D. Dreyfuss, Michael B. Fisch, Richard B. Fried, Varun N. Gehani, Nicolas Giauque, David T. Kim, Michael G. Linn, Rajiv A. Patel, Thomas G. Roberts, Jr., William Seybold, Andrew J. M. Spokes, John R. Warren and Mark C. Wehrly (collectively, the “Farallon Individual Reporting Persons”). Consists of 387,051 shares held by Farallon Capital Partners, L.P. (“FCP”), including 77,500 shares underlying exercisable warrants; 464,902 shares held by Farallon Capital Institutional Partners, L.P. (“FCIP”), including 292,500 shares underlying exercisable warrants; 83,661 shares held by Farallon Capital Institutional Partners II, L.P. (“FCIP II”), including 52,500 shares underlying exercisable warrants; 51,351 shares held by Farallon Capital Institutional Partners III, L.P. (“FCIP III”), including 33,800 shares underlying exercisable warrants; 71,643 shares held by Four Crossings Institutional Partners V, L.P. (“FCIP V”), including 45,000 shares underlying exercisable warrants; 1,026,633 shares held by Farallon Capital Offshore Investors II, L.P. (“FCOI II”), including 713,814 shares underlying exercisable warrants; 28,302 shares held by Farallon Capital (AM) Investors, L.P. (“FCAMI”), including 15,000 shares underlying exercisable warrants; 119,519 shares held by Farallon Capital F5 Master I, L.P. (“F5”), including 69,886 shares underlying exercisable warrants; and 1,184,072 shares held by Farallon Healthcare Partners Master, L.P. (“FHPM”) (collectively FCP, FCIP, FCIP II, FCIP III, FCIP V, FCOI II, FCAMI, F5 and FHPM are the “Farallon Funds”). Farallon General Partner, as the (i) general partner of each of FCP, FCIP, FCIP II, FCIP III, FCOI II and FCAMI, and (ii) the sole member of the FCIP V General Partner, is deemed to be the beneficial owner of 3,297,615 shares, including 1,430,114 shares underlying exercisable warrants. The Farallon Individual Reporting Persons, each of whom is a managing member or senior managing member of the Farallon General Partner, and a manager or senior manager, as the case may be, of the FCIP V General Partner, the F5MI General Partner and the FHPM General Partner are each deemed to beneficially own 3,417,134 shares including 1,500,000 shares underlying exercisable warrants. The address of the principal business office of the beneficial owners is c/o Farallon Capital Management, L.L.C., One Maritime Plaza, Suite 2100, San Francisco, CA 94111.
(5)
This information is based solely upon Amendment No. 1 to Schedule 13G/A filed with the SEC on February 3, 2022 by BlackRock, Inc. (“BlackRock”). The Schedule 13G/A reports that BlackRock has sole voting power with respect to 3,241,671 shares and sole dispositive power with respect to 3,281,636 shares. BlackRock is located at 55 East 52nd Street, New York, NY 10055.
(6)
This information is based solely upon Amendment No. 3 to Schedule 13G/A jointly filed with the SEC on February 14, 2022 by RTW Investments LP and Roderick Wong. RTW Investments, LP and Roderick Wong report that they have shared voting and dispositive power with respect to 2,599,822 shares. Roderick Wong is the Managing Partner of RTW Investments LP. The address of RTW Investments, LP and Roderick Wong is 40 10th Avenue, Floor 7, New York, NY 10014. The address of RTW Master Fund, Ltd. is 190 Elgin Avenue, George Town, Grand Cayman KY1-9001, Cayman Islands.
(7)
This information is based solely upon a Schedule 13G filed with the SEC on February 10, 2022. State Street Corporation (“State Street”) reports that it has shared voting power with respect to 2,487,986 shares and shared dispositive power with respect to 2,571,570 shares. Shares are beneficially held by subsidiaries of State Street. The address of State Street is 1 Lincoln Street, Boston, MA 02111.
(8)
This information is based solely upon Amendment No. 1 to Schedule 13G filed jointly with the SEC by Johnson & Johnson (“J&J”), and Johnson & Johnson Innovation-JJDC, Inc. (“JJDC”) on February 2, 2021. JJDC is a wholly-owned subsidiary of J&J. The securities held by J&J and JJDC are directly beneficially owned by JJDC. J&J may be deemed to indirectly beneficially own the securities that are directly beneficially owned by JJDC. The board of directors of JJDC, which consists of Paulus Stoffels