ABOUT
THIS PROSPECTUS
This
prospectus is part of a registration statement on Form F-3 that we filed with the SEC under the Securities Act of 1933, as amended,
or the Securities Act. This prospectus and any accompanying prospectus supplement do not contain all of the information included
in the registration statement. For further information, we refer you to the registration statement, including its exhibits, filed
with the SEC. Statements contained in this prospectus and any accompanying prospectus supplement about the contents of any document
are not necessarily complete. If SEC rules require that a document be filed as an exhibit to the registration statement, please
see such document for a complete description of these matters.
This
prospectus only provides you with a general description of the securities being offered. Each time a selling shareholder sells
any of the offered securities, such selling shareholder will provide this prospectus and a prospectus supplement, if applicable,
that will contain specific information about the terms of the offering. The prospectus supplement may also add, update or change
any information contained in this prospectus. You should carefully read this prospectus, any prospectus supplement and any free
writing prospectus related to the applicable securities that is prepared by us or on our behalf or that is otherwise authorized
by us, together with the additional information described under the headings “Where You Can Find More Information”
and “Incorporation of Certain Documents by Reference.”
You
should rely only on the information contained or incorporated by reference in this prospectus, any prospectus supplement and any
free writing prospectus related to these securities that is prepared by us or on our behalf or that is otherwise authorized by
us. We have not authorized any other person to provide you with different information. If anyone provides you with different or
inconsistent information, you should not rely on it. You should assume that the information contained in this prospectus, any
prospectus supplement, any free writing prospectus and the documents incorporated by reference herein and therein is accurate
only as of their respective dates. Our business, financial condition, results of operations and prospects may have changed since
those dates. To the extent there is a conflict between the information contained in this prospectus and the prospectus supplement,
you should rely on the information in the prospectus supplement, provided that if any statement in one of these documents is inconsistent
with a statement in another document having a later date — for example, a document incorporated by reference into this prospectus
or any prospectus supplement — the statement in the document having the later date modifies or supersedes the earlier statement.
The
financial statements included in or incorporated by reference into this prospectus have been prepared in accordance with International
Financial Reporting Standards as issued by the International Accounting Standards Board. This may not be comparable to financial
statements of United States (“U.S.”) companies, which use U.S. generally accepted accounting principles (“U.S.
GAAP”). Our consolidated financial statements are subject to the standards of the Public Company Accounting Oversight Board
(United States) and the SEC independence standards.
Unless
otherwise stated, currency amounts in this prospectus are stated in United States dollars, or “$” or “US$”.
In
this prospectus and in any prospectus supplement, unless otherwise indicated, references to “we”, “us”,
“our”, “Aeterna Zentaris” or the “Company” are to Aeterna Zentaris Inc., a Canadian corporation,
and its consolidated subsidiaries, unless it is clear that such terms refer only to Aeterna Zentaris Inc. excluding its subsidiaries.
References to “selling shareholders” refer to those shareholders listed herein under “Selling Shareholders,”
and their transferees.
PROSPECTUS
SUMMARY
This
summary highlights selected information about us, this offering and information contained in greater detail elsewhere in this
prospectus and in the documents incorporated by reference herein. This summary is not complete and does not contain all of the
information that you should consider before investing in our securities. You should carefully read and consider this entire prospectus
and the documents, including financial statements and related notes, and information incorporated by reference into this prospectus,
including the financial statements and “Risk Factors” in this prospectus, before making an investment decision. If
you invest in our securities, you are assuming a high degree of risk.
Our
Company
Aeterna
Zentaris is a specialty biopharmaceutical company commercializing and developing therapeutics and diagnostic tests. The Company’s
lead product, Macrilen™ (macimorelin), is the first and only United States Food and Drug Administration (“FDA”)
and European Commission approved oral test indicated for the diagnosis of patients with adult growth hormone deficiency (“AGHD”).
Macrilen™ (macimorelin) is currently marketed in the United States through a license and assignment agreement, as amended
(the “License Agreement”) with Novo Nordisk Biopharm Limited (“Novo”). Aeterna Zentaris is also pursuing
the development of macimorelin for the diagnosis of child-onset growth hormone deficiency (“CGHD”), an area of significant
unmet need. In addition, we are actively pursuing business development opportunities for the commercialization of macimorelin
in the rest of the world in addition to other non-strategic assets to monetize their value.
Recent
Developments
Background
of the Offering
On
February 19, 2021, the Company sold, in an upsized firm commitment offering pursuant to an underwriting agreement dated February
16, 2021 (as amended and restated, the “Underwriting Agreement”), 20,509,746 common shares of the Company (the “Common
Shares”) to H.C. Wainwright & Co., LLC (“Wainwright”) at an offering price to the public of $1.45 per share,
less underwriting discounts and commissions. In addition, the Company sold an additional 3,076,461 Common Shares to Wainwright
at the same offering price to the public, less underwriting discounts and commissions, pursuant to Wainwright’s exercise
in full of their option to purchase additional securities, pursuant to the Underwriting Agreement.
Among
other items of compensation, the Company issue to Wainwright, or its designees, warrants (the “Warrants”) to purchase,
in the aggregate, 1,651,034 Common Shares (equal to 7% of the aggregate number of Common Shares sold under the offering). The
Warrants have a term of five years from the effective date of the offering and an exercise price of $1.8125, or 125% of the public
offering price.
The
purpose of the registration statement of which this prospectus is a part is to register for resale the 1,651,034 Common Shares
underlying the Warrants.
Corporate
Information
We
were incorporated on September 12, 1990 under the Canada Business Corporations Act (the “CBCA”) and continue to be
governed by the CBCA. Our registered address is located at 222 Bay Street, Suite 3000, P.O. Box 53, Toronto ON M5K 1E7 Canada
c/o Norton Rose Fulbright Canada LLP. Our principal executive offices are located at 315 Sigma Drive, Summerville,
South Carolina 29486; our telephone number is (843) 900-3223 and our website is www.zentaris.com. None of the documents or information
found on our website shall be deemed to be included in or incorporated by reference into this prospectus, unless such document
is specifically incorporated herein by reference. The SEC also maintains a website at www.sec.gov that contains reports, proxy
statements and other information regarding registrants that file electronically with the SEC.
We
currently have three wholly owned direct and indirect subsidiaries, Aeterna Zentaris GmbH (“AEZS Germany”), based
in Frankfurt am Main, Germany, Zentaris IVF GmbH, a direct wholly owned subsidiary of AEZS Germany, based in Frankfurt am Main,
Germany, and Aeterna Zentaris, Inc., an entity incorporated in the State of Delaware with an office based in Summerville, South
Carolina in the U.S.
This
Offering
We
are registering for resale by the selling shareholders named herein the 1,651,034 Common
Shares as described below.
Securities
being offered:
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1,651,034
of our Common Shares, no par value, and associated
Common Share Purchase Rights. Additional information on our share capital, including the Common Share Purchase Rights, is
provided in our Annual Information Form for the year ended December 31, 2020, filed with our Annual Report on Form 40-F for
the year ended December 31, 2020, as amended by Amendment No. 1 to Form 40-F filed with the SEC on March 29, 2021,
incorporated by reference to this prospectus.
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Use
of proceeds:
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We
will not receive any of the proceeds from the sale or other disposition of our Common Shares by the selling shareholders.
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NASDAQ
Capital Market and TSX symbol:
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AEZS
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Risk
factors:
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See
“Risk Factors” beginning on page 4 for risks you should consider before investing in our shares.
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RISK
FACTORS
Investing
in our securities involves a high degree of risk. Before making an investment decision, you should carefully consider the risks
described in this prospectus, any applicable prospectus supplement and any related free writing prospectus
and under the captions “Risk Factors” in any of our filings with the SEC, including the item captioned “Risk
Factors” in our most recent Annual Information Form filed with our most recent Annual Report on Form 40-F and subsequent
consolidated financial statements and corresponding management’s discussion and analysis filed with the Canadian securities
regulatory authorities and our Reports on Form 6-K furnished to the SEC including our unaudited interim consolidated financial
statements and corresponding management’s discussion and analysis. For additional information, please see the sources described
in “Where You Can Find More Information.”
These
risks are not the only risks we face. Additional risks not presently known to us, or that we currently view as immaterial, may
also impair our business, if any of the risks described in our SEC filings or any prospectus supplement or any additional
risks actually occur, our business, financial condition, results of operations and cash flows could be materially and adversely
affected. In that case, the value of our securities could decline substantially and you could lose all or part of your investment.
SPECIAL
NOTE ON FORWARD-LOOKING STATEMENTS
This
prospectus, any accompanying prospectus supplement and the documents incorporated herein by reference contain
forward-looking statements made pursuant to the safe-harbor provision of the U.S. Securities Litigation Reform Act of 1995, which
reflect our current expectations regarding future events. Forward-looking statements may include, but are not limited to statements
preceded by, followed by, or that include the words “will,” “expects,” “believes,” “intends,”
“would,” “could,” “may,” “anticipates,” and similar terms that relate to future
events, performance, or our results. Forward-looking statements involve known risks and uncertainties, including those discussed
in the item captioned “Risk Factors” in our most recent Annual Information Form filed with the relevant Canadian securities
regulatory and with the SEC as an exhibit to our most recent Annual Report on Form 40-F. Known and unknown risks and uncertainties
could cause our actual results to differ materially from those in forward-looking statements. Such risks include but are not limited
to:
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our ability to raise capital and obtain financing to continue our currently planned operations;
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our ability to maintain compliance with the continued listing requirements of the Nasdaq in order to maintain the listing of
our Common Shares on the Nasdaq;
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our ability to continue as a going concern, which is dependent, in part, on our ability to secure additional financing;
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our dependence on the success of Macrilen™ (macimorelin) and related out-licensing arrangements and the continued availability
of funds and resources to successfully commercialize the product, including our heavy reliance on the success of the license and
assignment agreement with Novo Nordisk A/S (“Novo”) for the commercialization of Macrilen™ for the diagnosis
of adult growth hormone deficiency in the United States;
●
our ability to enter into out-licensing, development, manufacturing, marketing and distribution agreements with other pharmaceutical
companies and keep such agreements in effect;
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our reliance on third parties for the manufacturing and commercialization of Macrilen™ (macimorelin);
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potential disputes with third parties, leading to delays in or termination of the manufacturing, development, out-licensing or
commercialization of our product candidates, or resulting in significant litigation or arbitration;
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uncertainties related to the regulatory process;
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unforeseen global instability, including the instability due to the global pandemic of the novel coronavirus;
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our ability to efficiently commercialize or out-license Macrilen™ (macimorelin) in other territories and for other indications
not covered by our license and assignment agreement with Novo;
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our reliance on the success of the pediatric clinical trial in the European Union (“E.U.”) and U.S. for Macrilen™
(macimorelin);
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the degree of market acceptance of Macrilen™ (macimorelin);
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our and our partners’ ability to obtain necessary approvals from the relevant regulatory authorities to enable us to use
the desired brand names for our product;
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our and our partners’ ability to successfully negotiate pricing and reimbursement in key markets in the E.U. for Macrilen™
(macimorelin);
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any evaluation of potential strategic alternatives to maximize potential future growth and shareholder value may not result in
any such alternative being pursued, and even if pursued, may not result in the anticipated benefits;
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our ability to protect our intellectual property;
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the timing and progress of the preclinical and clinical development of our product candidates; and
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the potential of liability arising from shareholder lawsuits and general changes in economic conditions.
More
detailed information about these and other factors is included under “Risk Factors” in this prospectus, any
accompanying prospectus supplement and in other documents incorporated herein by reference. Investors should consult the
Company’s quarterly and annual filings with the Canadian and U.S. securities commissions for additional information on risks
and uncertainties. Many of these factors are beyond our control. Future events may vary substantially from what we currently foresee.
You should not place undue reliance on such forward-looking statements. The Company disavows and is under no obligation to update
or alter such forward-looking statements whether as a result of new information, future results, events, developments or otherwise,
unless required to do so by a governmental authority or applicable law.
USE
OF PROCEEDS
Any
selling shareholder will receive all of the net proceeds from the sales of our Common Shares offered by such selling shareholder
pursuant to this prospectus.
SELLING
SHAREHOLDERS
February
2021 Offering
On
February 19, 2021, the Company sold, in an upsized firm commitment offering (the “Offering”) pursuant to an underwriting
agreement dated February 16, 2021 (as amended and restated, the “Underwriting Agreement”), 20,509,746 common shares
of the Company (the “Common Shares”) to H.C. Wainwright & Co., LLC (“Wainwright”) at an offering price
to the public of $1.45 per share, less underwriting discounts and commissions. In addition, the Company sold an additional 3,076,461
Common Shares to Wainwright at the same offering price to the public, less underwriting discounts and commissions, pursuant to
Wainwright’s exercise in full of their option to purchase additional securities, pursuant to the Underwriting Agreement.
Among
other items of compensation, the Company issue to Wainwright, or its designees, warrants (the “Warrants”) to purchase,
in the aggregate, 1,651,034 Common Shares (equal to 7% of the aggregate number of Common Shares sold under the offering). The
Warrants have a term of five years from the effective date of the offering and an exercise price of $1.8125, or 125% of the public
offering price. A holder will not have the right to exercise any portion of the Warrants if the holder (together with its affiliates)
would beneficially own in excess of 4.99% of our Common Shares outstanding immediately after giving effect to the exercise, as
such percentage ownership is determined in accordance with the terms of the Warrants. However, any holder may increase or decrease
such percentage not to exceed 9.99% of the common shares outstanding immediately after giving effect to the exercise, provided
that any increase will not be effective until the 61st day after such election.
If
a registration statement registering the resale of the Common Shares underlying the Warrants under the Securities Act is not effective
or available or an exemption from registration under the Securities Act is not available for the resale of such shares, the holder
may, in its sole discretion, elect to exercise the Warrants through a cashless exercise, in which case the holder would receive
upon such exercise the net number of Common Shares determined according to the formula set forth in the Warrants.
The
Warrants or the Common Shares issuable upon exercise of the Warrants have not been registered under the Securities Act, or any
state securities laws. The Warrants were issued in reliance upon the exemption from the registration requirements of the Securities
Act under Section 4(a)(2) of the Securities Act regarding transactions not involving a public offering, including Rule 506 of
Regulation D promulgated thereunder.
All
of these unregistered Warrants remain unexercised.
Each
of Noam Rubinstein, Charles Worthman, Michael Vasinkevich and Craig Schwabe are affiliated with Wainwright, a registered broker-dealer.
Wainwright and/or any of its affiliates previously served as underwriter for the Offering, as our placement agent for offerings
that closed in August 2020, July 2020 and February 2020, as sales agent for an at-the-market offering pursuant to a sales agreement
dated April 27, 2017 and as financial advisor from time to time in the ordinary course of their business, for which they have
received customary fees and commissions.
Information
About Selling Shareholder Offering
We
are registering the resale of the above-referenced Common Shares, and associated Common Share purchase rights, to permit each
of the selling shareholders identified below, or their permitted transferees or other successors-in-interest that may be identified
in a supplement to this prospectus or, if required, a post-effective amendment to the registration statement of which this prospectus
is a part, to resell or otherwise dispose of the Common Shares in the manner contemplated under “Plan of Distribution”
in this prospectus (as may be supplemented and amended). This prospectus covers the sale or other disposition by the selling shareholders
of up to the total number of Common Shares issuable upon cash exercise of the Warrants issued to Wainwright,
or its designees in February 2021, which are held by the selling shareholders. Throughout this prospectus, when we refer
to the Common Shares being registered on behalf of the selling shareholders, we are referring to the Common Shares issuable upon
cash exercise of the Warrants, and when we refer to the selling shareholders in this prospectus, we are referring to the current
holders of the warrants issued to Wainwright, or its designees in February 2021,
and their permitted transferees or other successors-in-interest that may be identified in a supplement to this prospectus or,
if required, a post-effective amendment to the registration statement of which this prospectus is a part.
The
selling shareholders may sell some, all or none of their Common Shares. We do not know when or whether any of the selling shareholders
will exercise their Warrants, nor do we know how long the selling shareholders will hold their Common Shares before selling them,
and we currently have no agreements, arrangements or understandings with the selling shareholders regarding the exercise of any
Warrants, or the sale or other disposition of any of the Common Shares. The Common Shares covered hereby may be offered from time
to time by the selling shareholders.
The
following table sets forth the name of each of the selling shareholders, the number of our Common Shares beneficially owned by
the selling shareholders as of March 18, 2021, the number of our Common Shares issuable upon exercise of Warrants that may be
offered under this prospectus, and the number and percentage of our Common Shares beneficially owned by the selling shareholders
assuming all of the Common Shares registered hereunder are sold. Beneficial ownership is determined in accordance with the rules
of the SEC and includes voting or investment power with respect to our Common Shares. Generally, a person “beneficially
owns” Common Shares if the person has or shares with others the right to vote those shares or to dispose of them, or if
the person has the right to acquire voting or disposition rights within 60 days. The number of Common Shares in the column “Number
of Shares Offered” represents all of the Common Shares that a selling shareholder may offer and sell from time to time under
this prospectus.
The
information in the table below and the footnotes thereto regarding Common Shares to be beneficially owned after the offering assumes
that the selling shareholders have exercised their Warrants in full pursuant to cash exercises and further assumes the sale of
all Common Shares being offered by the selling shareholders under this prospectus.
Unless
otherwise indicated, all information contained in the table below and the footnotes thereto is based upon information provided
to us by the selling shareholders. The percentage of shares owned prior to and after the offering is based on 121,124,785
of our Common Shares outstanding as of March 18, 2021. Unless otherwise indicated in the footnotes to this table, we believe that
each of the selling shareholders named in this table has sole voting and investment power with respect to the Common Shares indicated
as beneficially owned. Except as otherwise indicated in this section, based on the information provided to us by the selling shareholders,
and to the best of our knowledge, none of the selling shareholders is a broker-dealer or an affiliate of a broker-dealer.
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Common Shares Beneficially Owned Prior to the Offering
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Number of Common Shares Registered Hereby
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Common Shares Beneficially Owned After the Offering
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Number
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for Sale
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Number
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Percent
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Noam Rubenstein (1)(5)
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596,772
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520,076
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76,696
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*
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Charles Worthman (2)(5)
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18,946
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16,511
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2,435
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*
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Michael Vasinkevich (3)(5)
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1,214,855
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1,058,725
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156,130
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*
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Craig Schwabe (4)(5)
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63,939
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55,722
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8,217
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*
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Total Common Shares- Registered Hereby:
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1,651,034
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(1)
Consists of 520,076 Commons Shares underlying the Warrants and 76,696 Common Shares underlying other
warrants issued in February 2020, without giving effect to limitation and beneficial ownership set forth therein.
(2)
Consists of 16,511 Commons Shares underlying the Warrants and 2,435 Common Shares underlying other warrants issued in February
2020, without giving effect to limitation and beneficial ownership set forth therein.
(3)
Consists of 1,058,725 Commons Shares underlying the Warrants and 156,130 Common Shares underlying other warrants issued in
February 2020, without giving effect to limitation and beneficial ownership set forth therein.
(4)
Consists of 55,722 Commons Shares underlying the Warrants and 8,217 Common Shares underlying other warrants issued in February
2020, without giving effect to limitation and beneficial ownership set forth therein.
(5)
Each of Noam Rubinstein, Charles Worthman, Michael Vasinkevich and Craig Schwabe have a registered address of 430 Park Ave, 3rd
Floor, New York, NY 10022.
DESCRIPTION
OF SHARE CAPITAL
Our
authorized share capital structure consists of an unlimited number of shares of the following classes (all classes are without
nominal or par value): Common Shares; and first preferred shares (the “First Preferred Shares”) and second preferred
shares (the “Second Preferred Shares” and, together with the First Preferred Shares, the “Preferred Shares”),
each issuable in series. As of March 18, 2021, there were 121,124,785 Common Shares issued and outstanding, which have associated
Common Share purchase rights under our Shareholder Rights Plan Agreement. No Preferred Shares have been issued to date. See our
Annual Information Form for the year ended December 31, 2020, filed with our Annual Report on Form 40-F for the year ended December
31, 2020, as amended by Amendment No. 1 to Form 40-F filed with the SEC on March 29, 2021 , which is incorporated herein
by reference.
INCOME
TAX CONSIDERATIONS
THE
FOLLOWING SUMMARY IS OF A GENERAL NATURE ONLY AND IS NOT INTENDED TO BE, NOR SHOULD IT BE CONSTRUED TO BE, LEGAL OR TAX ADVICE
TO ANY PARTICULAR INVESTOR. CONSEQUENTLY, PROSPECTIVE INVESTORS ARE URGED TO CONSULT THEIR OWN TAX ADVISORS FOR ADVICE AS TO THE
TAX CONSEQUENCES OF AN INVESTMENT IN THE SECURITIES OFFERED BY THIS PROSPECTUS HAVING REGARD TO THEIR PARTICULAR CIRCUMSTANCES.
Material
U.S. Federal Income Tax Considerations for U.S. Holders
The
following discussion is a summary of the material U.S. federal income tax consequences applicable to the purchase, ownership and
disposition of Common Shares being offered by this prospectus by a U.S. Holder (as defined below), but does not purport to be
a complete analysis of all potential U.S. federal income tax effects.
This
summary is based on the Internal Revenue Code of 1986, as amended (the “Code”), U.S. Treasury regulations promulgated
thereunder, IRS rulings and judicial decisions in effect on the date of this prospectus. All of these are subject to change, possibly
with retroactive effect, or different interpretations. This summary does not discuss the potential effects, whether adverse or
beneficial, of any proposed legislation that, if enacted, could be applied on a retroactive basis. This summary is not binding
on the IRS, and the IRS is not precluded from taking a position that is different from, and contrary to, the positions taken in
this summary.
This
summary does not address all aspects of U.S. federal income taxation that may be relevant to particular U.S. Holders in light
of their specific circumstances (for example, U.S. Holders subject to the alternative minimum tax or the Medicare contribution
tax on net investment income under the Code) or to holders that may be subject to special rules under U.S. federal income tax
law, including, without limitation:
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dealers
in stocks, securities or currencies;
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securities
traders that use a mark-to-market accounting method;
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banks
and financial institutions;
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insurance
companies;
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regulated
investment companies;
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real
estate investment trusts;
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tax-exempt
organizations;
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retirement
plans, individual plans, individual retirement accounts and tax-deferred accounts;
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partnerships
or other pass-through entities for U.S. federal income tax purposes and their partners or members;
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persons
holding Common Shares as part of a hedging or conversion transaction straddle or other integrated or risk reduction transaction;
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persons
who or that are, or may become, subject to the expatriation provisions of the Code;
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persons
whose functional currency is not the U.S. dollar; and
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direct,
indirect or constructive owners of 10% or more of the total combined voting power of all classes of our voting stock or 10%
or more of the total value of shares of all classes of our stock.
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This
summary also does not discuss any aspect of state, local or foreign law, or estate or gift tax law as applicable to U.S. Holders.
In addition, this discussion is limited to U.S. Holders purchasing Common Shares pursuant to this prospectus and that will hold
such Common Shares as capital assets. For purposes of this summary, “U.S. Holder” means a beneficial holder of Common
Shares who or that for U.S. federal income tax purposes is:
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an
individual citizen or resident of the U.S.;
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a
corporation or other entity classified as a corporation for U.S. federal income tax purposes created or organized in or under
the laws of the U.S., any state thereof or the District of Columbia;
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an
estate, the income of which is subject to U.S. federal income taxation regardless of its source; or
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a
trust, if (a) a court within the U.S. is able to exercise primary supervision over the administration of such trust and one
or more “U.S. persons” (within the meaning of the Code) have the authority to control all substantial decisions
of the trust, or (b) a valid election is in effect to be treated as a U.S. person for U.S. federal income tax purposes.
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If
a partnership or other entity or arrangement classified as a partnership for U.S. federal income tax purposes holds Common Shares,
the U.S. federal income tax treatment of a partner generally will depend on the status of the partner and the activities of the
partnership. This summary does not address the tax consequences to any such partner. Such a partner should consult its own tax
advisor as to the tax consequences of the partnership purchasing, owning and disposing of Common Shares.
PROSPECTIVE
INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISORS WITH REGARD TO THE APPLICATION OF THE TAX CONSEQUENCES DESCRIBED BELOW TO THEIR
PARTICULAR SITUATIONS AS WELL AS THE APPLICATION OF ANY STATE, LOCAL, FOREIGN OR OTHER TAX LAWS, INCLUDING GIFT AND ESTATE TAX
LAWS.
Tax
Consequences if we are a Passive Foreign Investment Company
A
foreign corporation will be classified as a PFIC for any taxable year in which, after taking into account the income and assets
of the corporation and certain subsidiaries pursuant to applicable “look-through rules,” either (i) at least 75% of
its gross income is “passive income” or (ii) at least 50% of the average quarterly value of its assets is attributable
to assets which produce passive income or are held for the production of passive income. Passive income generally includes dividends,
interest, rents and royalties (other than certain rents and royalties derived in the active conduct of a trade or business), annuities
and gains from assets that produce passive income. If a non-U.S. corporation owns at least 25% by value of the stock of another
corporation, the non-U.S. corporation is treated for purposes of the PFIC tests as owning its proportionate share of the assets
of the other corporation and as receiving directly its proportionate share of the other corporation’s income.
The
determination of whether we are, or will be, a PFIC for a taxable year depends, in part, on the application of complex U.S. federal
income tax rules, which are subject to various interpretations. Although the matter is not free from doubt, we believe that we
were not a PFIC during our 2020 taxable year and will not likely be a PFIC during our 2021 taxable year. Because PFIC status is
based on our income, assets and activities for the entire taxable year, and our market capitalization, it is not possible to determine
whether we will be characterized as a PFIC for the 2021 taxable year until after the close of the taxable year. The tests for
determining PFIC status are subject to a number of uncertainties. These tests are applied annually, and it is difficult to accurately
predict future income, assets and activities relevant to this determination. In addition, because the market price of our Common
Shares is likely to fluctuate, the market price may affect the determination of whether we will be considered a PFIC. There can
be no assurance that we will not be considered a PFIC for any taxable year (including our 2021 taxable year). Prospective investors
should consult their tax advisors regarding the Company’s PFIC status.
If
the Company is classified as a PFIC for any taxable year during which a U.S. Holder owns Common Shares, the U.S. Holder, absent
certain elections (including the mark-to-market and QEF elections described below), will generally be subject to adverse rules
(regardless of whether the Company continues to be classified as a PFIC) with respect to (i) any “excess distributions”
(generally, any distributions received by the U.S. Holder on the Common Shares in a taxable year that are greater than 125% of
the average annual distributions received by the U.S. Holder in the three preceding taxable years or, if shorter, the U.S. Holder’s
holding period for the Common Shares) and (ii) any gain realized on the sale or other disposition of the Common Shares.
Under
these adverse rules (a) the excess distribution or gain will be allocated ratably over the U.S. Holder’s holding period,
(b) the amount allocated to the current taxable year and any taxable year prior to the first taxable year in which the Company
is classified as a PFIC will be taxed as ordinary income and (c) the amount allocated to each of the other taxable years during
which the Company was classified as a PFIC will be subject to tax at the highest rate of tax in effect for the applicable category
of taxpayer for that year and an interest charge will be imposed with respect to the resulting tax attributable to each such other
taxable year. A U.S. Holder that is not a corporation will be required to treat any such interest paid as “personal interest,”
which is not deductible.
U.S.
Holders can avoid the adverse rules described above in part by making a mark-to-market election with respect to the Common Shares,
provided that the Common Shares are “marketable.” The Common Shares will be marketable if they are “regularly
traded” on a “qualified exchange” or other market within the meaning of applicable U.S. Treasury regulations.
For this purpose, the Common Shares generally will be considered to be regularly traded during any calendar year during which
they are traded, other than in de minimis quantities, on at least 15 days during each calendar quarter. The Common Shares
are currently listed on the NASDAQ, which constitutes a qualified exchange; however, there can be no assurance that the Common
Shares will be treated as regularly traded for purposes of the mark-to-market election on a qualified exchange. If the Common
Shares were not regularly traded on the NASDAQ or were delisted from the NASDAQ and were not traded on another qualified exchange
for the requisite time period described above, the mark-to-market election would not be available.
A
U.S. Holder that makes a mark-to-market election must include in gross income, as ordinary income, for each taxable year an amount
equal to the excess, if any, of the fair market value of the U.S. Holder’s Common Shares at the close of the taxable year
over the U.S. Holder’s adjusted tax basis in the Common Shares. An electing U.S. Holder may also claim an ordinary loss
deduction for the excess, if any, of the U.S. Holder’s adjusted tax basis in the Common Shares over the fair market value
of the Common Shares at the close of the taxable year, but this deduction is allowable only to the extent of any net mark-to-market
gains previously included in income. A U.S. Holder that makes a mark-to-market election generally will adjust such U.S. Holder’s
tax basis in the Common Shares to reflect the amount included in gross income or allowed as a deduction because of such mark-to-market
election. Gains from an actual sale or other disposition of the Common Shares will be treated as ordinary income, and any losses
incurred on a sale or other disposition of the Common Shares will be treated as ordinary losses to the extent of any net mark-to-market
gains previously included in income.
If
we are classified as a PFIC for any taxable year in which a U.S. Holder owns Common Shares, but before a mark-to-market election
is made, the adverse PFIC rules described above will apply to any mark-to-market gain recognized in the year the election is made.
Otherwise, a mark-to-market election will be effective for the taxable year for which the election is made and all subsequent
taxable years. The election cannot be revoked without the consent of the IRS unless the Common Shares cease to be marketable,
in which case the election is automatically terminated.
If
the Company is classified as a PFIC, a U.S. Holder of Common Shares will generally be treated as owning stock owned by the Company
in any direct or indirect subsidiaries that are also PFICs and will be subject to similar adverse rules with respect to distributions
to the Company by, and dispositions by the Company of, the stock of such subsidiaries. A mark-to-market election is not permitted
for the shares of any subsidiary of the Company that is also classified as a PFIC. Prospective investors should consult their
tax advisors regarding the availability of, and procedure for making, a mark-to-market election.
In
some cases, a shareholder of a PFIC can avoid the interest charge and the other adverse PFIC consequences described above by making
a QEF election to be taxed currently on its share of the PFIC’s undistributed income. We will endeavor to satisfy the record
keeping requirements that apply to a QEF and to supply requesting U.S. Holders with the information that such U.S. Holders are
required to report under the QEF rules. There can be no assurance, however, that we will satisfy the record keeping requirements
or provide the information required to be reported by U.S. Holders.
A
U.S. Holder that makes a timely and effective QEF election for the first tax year in which its holding period of its Common Shares
begins generally will not be subject to the adverse PFIC consequences described above with respect to its Common Shares. Rather,
a U.S. Holder that makes a timely and effective QEF election will be subject to U.S. federal income tax on such U.S. Holder’s
pro rata share of (a) the Company’s net capital gain, which will be taxed as long-term capital gain to such U.S. Holder,
and (b) the Company’s ordinary earnings, which will be taxed as ordinary income to such U.S. Holder, in each case regardless
of which such amounts are actually distributed to the U.S. Holder by the Company. Generally, “net capital gain” is
the excess of (i) net long-term capital gain over (ii) net short-term capital loss, and “ordinary earnings” are the
excess of (A) “earnings and profits” over (B) net capital gain.
A
U.S. Holder that makes a timely and effective QEF election with respect to the Company generally (a) may receive a tax-free distribution
from us to the extent that such distribution represents “earnings and profits” that were previously included in income
by the U.S. Holder because of such QEF election and (b) will adjust such U.S. Holder’s tax basis in the Common Shares to
reflect the amount included in income or allowed as a tax-free distribution because of such QEF election. In addition, a U.S.
Holder that makes a QEF election generally will recognize capital gain or loss on the sale or other taxable disposition of Common
Shares.
The
QEF election is made on a shareholder-by-shareholder basis. Once made, a QEF election will apply to the tax year for which the
QEF election is made and to all subsequent tax years, unless the QEF election is invalidated or terminated or the IRS consents
to revocation of the QEF election. In addition, if a U.S. Holder makes a QEF election, the QEF election will remain in effect
(although it will not be applicable) during those tax years in which we are not a PFIC.
If
the Company is classified as a PFIC and then ceases to be so classified, a U.S. Holder may make an election (a “deemed sale
election”) to be treated for U.S. federal income tax purposes as having sold such U.S. Holder’s Common Shares on the
last day of the taxable year of the Company during which it was a PFIC. A U.S. Holder that made a deemed sale election would then
cease to be treated as owning stock in a PFIC by reason of ownership of Common Shares in the Company. Any gain recognized, however,
as a result of making the deemed sale election would be subject to the adverse rules described above and loss would not be recognized.
If
the Company is a PFIC in any year with respect to a U.S. Holder, the U.S. Holder will be required to file an annual information
return on IRS Form 8621 regarding distributions received on Common Shares and any gain realized on the disposition of Common Shares.
In
addition, if the Company is a PFIC, U.S. Holders will generally be required to file an annual information return with the IRS
(also on IRS Form 8621, which PFIC shareholders are required to file with their U.S. federal income tax or information returns)
relating to their ownership of Common Shares.
Prospective
investors should consult their tax advisors regarding the potential application of the PFIC regime and any reporting obligations
to which they may be subject under that regime.
Taxation
of Distributions
Subject
to the PFIC rules discussed above, any distributions paid by us out of current or accumulated earnings and profits (as determined
for U.S. federal income tax purposes), before reduction for any Canadian withholding tax paid with respect thereto, will generally
be taxable to a U.S. Holder as foreign source dividend income, and generally will not be eligible for the dividends received deduction
generally allowed to corporations.
Distributions
in excess of current and accumulated earnings and profits will be treated as a non-taxable return of capital to the extent of
the U.S. Holder’s adjusted tax basis in the Common Shares and, thereafter, as capital gain. We do not, however, intend to
calculate our earnings and profits under U.S. federal income tax principles. Therefore, U.S. Holders should expect that any distribution
from us generally will be treated for U.S. federal income tax purposes as a dividend. Prospective investors should consult their
own tax advisors with respect to the appropriate U.S. federal income tax treatment of any distribution received from us.
Dividends
paid to non-corporate U.S. Holders by us in a taxable year in which we are treated as a PFIC, or in the immediately following
taxable year, will not be eligible for the special reduced rates normally applicable to long-term capital gains. In all other
taxable years, dividends paid by us should be taxable to a non-corporate U.S. Holder at the special reduced rates normally applicable
to long-term capital gains, provided that certain conditions are satisfied (including a minimum holding period requirement). We
believe we were not a PFIC for the 2020 taxable year. However, no assurance can be provided that we will not be classified as
a PFIC for 2021 and, therefore, no assurance can be provided that a U.S. Holder will be able to claim a reduced rate for dividends
paid in 2020 or 2021 (if any). Please see the subsection above entitled “Material U.S. Federal Income Tax Considerations
for U.S. Holders — Tax Consequences if we are a Passive Foreign Investment Company” for a more detailed discussion.
Under
current law, payments of dividends by us to non-Canadian investors are generally subject to a 25% Canadian withholding tax. The
rate of withholding tax applicable to U.S. Holders that are eligible for benefits under the Canada-United States Tax Convention
(the “Convention”) is reduced to a maximum of 15%. This reduced rate of withholding will not apply if the dividends
received by a U.S. Holder are effectively connected with a permanent establishment of the U.S. Holder in Canada. For U.S. federal
income tax purposes, U.S. Holders will be treated as having received the amount of Canadian taxes withheld by the Company, and
as then having paid over the withheld taxes to the Canadian taxing authorities. As a result of this rule, the amount of dividend
income included in gross income for U.S. federal income tax purposes by a U.S. Holder with respect to a payment of dividends may
be greater than the amount of cash actually received (or receivable) by the U.S. Holder from the Company with respect to the payment.
Subject
to certain limitations, a U.S. Holder will generally be entitled, at the election of the U.S. Holder, to a credit against its
U.S. federal income tax liability, or a deduction in computing its U.S. federal taxable income, for Canadian income taxes withheld
by us. This election is made on a year-by-year basis and applies to all foreign taxes paid (whether directly or through withholding)
by a U.S. Holder during a year. For purposes of the foreign tax credit limitation, dividends paid by us generally will constitute
foreign source income in the “passive category income” basket. The foreign tax credit rules are complex and prospective
investors should consult their tax advisors concerning the availability of the foreign tax credit in their particular circumstances.
Dividends
paid in Canadian dollars will be included in the gross income of a U.S. Holder in a U.S. dollar amount calculated by reference
to the exchange rate in effect on the date the U.S. Holder (actually or constructively) receives the dividend, regardless of whether
such Canadian dollars are actually converted into U.S. dollars at that time. If the Canadian dollars received are not converted
into U.S. dollars on the date of receipt, a U.S. Holder will have a tax basis in the Canadian dollars equal to their U.S. dollar
value on the date of receipt. Gain or loss, if any, realized on a sale or other disposition of the Canadian dollars will generally
be U.S. source ordinary income or loss to a U.S. Holder.
We
generally do not pay any dividends and do not anticipate paying any dividends in the foreseeable future.
Sale,
Exchange or Other Taxable Disposition of Common Shares
Subject
to the PFIC rules discussed above, upon a sale, exchange or other taxable disposition of Common Shares, a U.S. Holder generally
will recognize capital gain or loss for U.S. federal income tax purposes equal to the difference, if any, between the amount realized
on the sale, exchange or other taxable disposition and the U.S. Holder’s adjusted tax basis in the Common Shares.
This
capital gain or loss will be long-term capital gain or loss if the U.S. Holder’s holding period in the Common Shares exceeds
one year. The deductibility of capital losses is subject to limitations. Any gain or loss will generally be U.S. source for U.S.
foreign tax credit purposes.
Information
Reporting and Backup Withholding
In
general, information reporting for U.S. federal income tax purposes should apply to distributions made on our securities within
the United States to a U.S. Holder (other than an exempt recipient) and to the proceeds from sales and other dispositions of our
securities by a U.S. Holder (other than an exempt recipient) to or through a U.S. office of a broker. Payments made (and sales
and other dispositions effected at an office) outside the United States will be subject to information reporting in limited circumstances.
In addition, certain information concerning a U.S. Holder’s adjusted tax basis in securities it owns and adjustments to
that tax basis and whether any gain or loss with respect to such securities is long term or short term also may be required to
be reported to the IRS.
In
addition, U.S. federal income tax information reporting rules generally require certain individuals who are U.S. Holders to file
IRS Form 8938 to report the ownership of specified foreign financial assets if the total value of those assets exceeds an applicable
threshold amount (subject to certain exceptions). For these purposes, a specified foreign financial asset includes not only a
financial account (as defined for these purposes) maintained by a foreign financial institution, but also any stock or security
issued by a non-U.S. person, any financial instrument or contract held for investment that has an issuer or counterparty other
than a U.S. person and any interest in a foreign entity, provided that the asset is not held in an account maintained by a financial
institution. The minimum applicable threshold amount is generally U.S. $50,000 in the aggregate, but this threshold amount varies
depending on whether the individual lives in the U.S., is married, files a joint income tax return with his or her spouse, and
on certain other factors. Certain domestic entities that are U.S. Holders may also be required to file IRS Form 8938 if both (i)
such entities are owned at least 80% by an individual who is a U.S. citizen or U.S. tax resident (or in some cases, by a nonresident
alien who meets certain criteria) or are trusts with beneficiaries that are such individuals and (ii) more than 50% of their income
consists of certain passive income or more than 50% of their assets is held for the production of such income. U.S. Holders are
urged to consult with their tax advisors regarding their reporting obligations, including the requirement to file IRS Form 8938.
U.S.
Holders who transfer more than $100,000 to us in a 12-month period (and/or who become owners of 10% or more of our securities)
will be required to file IRS Form 926, Return by U.S. Transferor of Property to a Foreign Corporation, and U.S. Holders who become
holder of more than 10% of our securities may also have to file IRS Form 5471, Information Return of U.S. Persons With Respect
to Certain Foreign Corporations, in each case reporting transfers of cash or other property to us and information relating to
the U.S. Holder and us. Substantial penalties may be imposed upon a U.S. Holder that fails to comply with these filing requirements.
U.S. Holders should consult their own tax advisors about the need to file either of these forms. See also the discussion, above,
regarding IRS Form 8621, Information Return by a Shareholder of a Passive Foreign Investment Company or Qualified Electing Fund.
Backup
withholding of U.S. federal income tax, currently at a rate of 24%, generally will apply to dividends paid on our securities to
a U.S. Holder (other than an exempt recipient) and the proceeds from sales and other dispositions of our securities by a U.S.
Holder (other than an exempt recipient), in each case who:
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fails
to provide an accurate taxpayer identification number;
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is
notified by the IRS that backup withholding is required; or
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in
certain circumstances, fails to comply with applicable certification requirements.
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A
non-U.S. Holder generally may eliminate the requirement for information reporting and backup withholding by providing certification
of its foreign status, under penalties of perjury, on a duly executed applicable IRS Form W-8 or by otherwise establishing an
exemption.
Backup
withholding is not an additional tax. Rather, the amount of any backup withholding will be allowed as a credit against a U.S.
Holder’s U.S. federal income tax liability and may entitle such holder to a refund, provided that certain required information
is timely furnished to the IRS.
Holders
are urged to consult their own tax advisors regarding the application of backup withholding and the availability of and procedures
for obtaining an exemption from backup withholding in their particular circumstances.
Canadian
Federal Income Tax Considerations For U.S. Holders
The
following is a general summary, as of the date hereof, of the principal Canadian federal income tax considerations generally applicable
to the holding and disposition Common Shares acquired pursuant to this prospectus by a holder who, at all relevant times, (a)
for the purposes of the Income Tax Act (Canada) (the “Tax Act”), (i) is not resident, or deemed to be resident, in
Canada, (ii) deals at arm’s length with, and is not affiliated with, the Company, (iii) beneficially owns Common Shares
as capital property, (iv) does not use or hold the Common Shares in the course of carrying on, or otherwise in connection with,
a business or a part of a business carried on or deemed to be carried on in Canada, and (v) is not a “registered non-resident
insurer” or “authorized foreign bank” within the meaning of the Tax Act, and (b) for the purposes of the Convention,
is a resident of the U.S., has never been a resident of Canada, does not have and has not had, at any time, a permanent establishment
or fixed base in Canada, and is a qualifying person or otherwise qualifies for the full benefits of the Convention. Common Shares
will generally be considered to be capital property to a holder unless such Common Shares are held in the course of carrying on
a business of buying or selling securities or an adventure or concern in the nature of trade. Holders who meet all the criteria
in clauses (a) and (b) are referred to herein as a “U.S. Holder” or “U.S. Holders.” This summary does
not deal with special situations, such as the particular circumstances of traders or dealers or holders who have entered or will
enter into a “derivative forward agreement” (as defined in the Tax Act) in respect of any of the Common Shares. Such
holders and other holders who do not meet the criteria in clauses (a) and (b) should consult their own tax advisors.
This
summary is based upon the current provisions of the Tax Act and the regulations thereunder (the “Regulations”) and
counsel’s understanding of the current administrative policies and assessing practices of the Canada Revenue Agency (the
“CRA”) made publicly available prior to the date hereof. It also takes into account all proposed amendments to the
Tax Act and the Regulations publicly released by the Minister of Finance (Canada) (the “Tax Proposals”) prior to the
date hereof, and assumes that all such Tax Proposals will be enacted as currently proposed. No assurance can be given that the
Tax Proposals will be enacted in the form proposed or at all. This summary does not otherwise take into account or anticipate
any changes in law, whether by way of legislative, judicial or administrative action or interpretation, nor does it take into
account tax laws of any province or territory of Canada or of any other jurisdiction outside Canada.
This
summary is of a general nature only and is not intended to be, nor should it be construed to be, legal or tax advice to any particular
U.S. Holder and no representation with respect to the federal income tax consequences to any particular U.S. Holder or prospective
U.S. Holder is made. The tax consequences to a U.S. Holder will depend on the holder’s particular circumstances. Accordingly,
U.S. Holders should consult with their own tax advisors for advice with respect to their own particular circumstances.
Currency
Conversion
In
general, for purposes of the Tax Act, all amounts relating to the acquisition, holding or disposition of the Common Shares must
be converted into Canadian dollars based on the applicable exchange rate quoted by the Bank of Canada for the relevant day or
such other rate of exchange that is acceptable to the Minister of National Revenue (Canada).
Dividends
Amounts
paid or credited or deemed to be paid or credited as, on account or in lieu of payment, or in satisfaction of, dividends on the
Common Shares to a U.S. Holder will be subject to Canadian withholding tax. Under the Convention, the rate of Canadian withholding
tax on dividends paid or credited by the Company to a U.S. Holder that beneficially owns such dividends is generally 15% unless
the beneficial owner is a company that owns at least 10% of the Company’s voting stock at that time, in which case the rate
of Canadian withholding tax is reduced to 5%.
Dispositions
Upon
the disposition of a Common Share, a U.S. Holder will realize a capital gain (or capital loss) in the taxation year of the disposition
equal to the amount by which the U.S. Holder’s proceeds of disposition, net of any reasonable costs of disposition, exceed
(or are exceeded by) the adjusted cost base to the U.S. Holder of the Common Shares immediately before the disposition or deemed
disposition.
A
U.S. Holder will not be subject to tax under the Tax Act in respect of any capital gain realized by such U.S. Holder on a disposition
of Common Shares, unless such Common Shares constitute “taxable Canadian property” (as defined in the Tax Act) of
the U.S. Holder at the time of disposition and the U.S. Holder is not entitled to relief under the Convention.
Provided
that the Common Shares are listed on a designated stock exchange for purposes of the Tax Act (which currently includes the NASDAQ
and the TSX) at the time of the disposition, the Common Shares generally will not constitute taxable Canadian property of a U.S.
Holder, unless: (a) at any time during the 60-month period immediately preceding the disposition or deemed disposition of the
Common Shares (as applicable): (i) 25% or more of the issued shares of any class or series of the share capital of the Company
were owned by, or belonged to, one or any combination of (x) the U.S. Holder, (y) persons with whom the U.S. Holder did not deal
at arm’s length (within the meaning of the Tax Act) and (z) partnerships in which the U.S. Holder or a person referred to
in (y) holds a membership interest directly or indirectly through one or more partnerships; and (ii) more than 50% of the fair
market value of the Common Shares was derived directly or indirectly from one or any combination of: (A) real or immovable property
situated in Canada, (B) Canadian resource property (as defined in the Tax Act), (C) timber resource property (as defined in the
Tax Act), and (D) options in respect of, or interests in, or for civil law rights in, property described in any of (A) through
(C) above, whether or not such property exists; or (b) the Common Shares is deemed under the Tax Act to be taxable Canadian property.
If
a Common Share is taxable Canadian property to a U.S. Holder, any capital gain realized on the disposition or deemed disposition
of such Common Share may not be subject to Canadian federal income tax pursuant to the terms of the Convention. Non-Resident Holders
whose Common Share may be taxable Canadian property should consult their own tax advisors.
PLAN
OF DISTRIBUTION
We
are registering the Common Shares (and associated purchase rights) issued and issuable upon exercise of the Warrants to permit
the resale of these Common Shares by the holders of the Warrants from time to time after the date of this prospectus. We will
not receive any of the proceeds from the sale by the selling shareholders of the Common Shares. We will bear all fees and expenses
incident to our obligation to register the Common Shares.
The
selling shareholders may sell all or a portion of the Common Shares beneficially owned by them and offered hereby from time to
time directly or through one or more underwriters, broker-dealers or agents. If the Common Shares are sold through underwriters
or broker-dealers, the selling shareholders will be responsible for underwriting discounts or commissions or agent’s commissions.
The Common Shares may be sold in one or more transactions at fixed prices, at prevailing market prices at the time of the sale,
at varying prices determined at the time of sale, or at negotiated prices. These sales may be effected in transactions, which
may involve crosses or block transactions,
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on
any national securities exchange or quotation service on which the securities may be listed or quoted at the time of sale;
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in
the over-the-counter market;
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in
transactions otherwise than on these exchanges or systems or in the over-the-counter market;
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through
the writing of options, whether such options are listed on an options exchange or otherwise;
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ordinary
brokerage transactions and transactions in which the broker-dealer solicits purchasers;
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block
trades in which the broker-dealer will attempt to sell the shares as agent but may position and resell a portion of the block
as principal to facilitate the transaction;
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purchases
by a broker-dealer as principal and resale by the broker-dealer for its account;
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an
exchange distribution in accordance with the rules of the applicable exchange;
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privately
negotiated transactions;
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short
sales;
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sales
pursuant to Rule 144;
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broker-dealers
may agree with the selling shareholders to sell a specified number of such shares at a stipulated price per share;
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a
combination of any such methods of sale; and
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any
other method permitted pursuant to applicable law.
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If
the selling shareholders effect such transactions by selling Common Shares to or through underwriters, broker-dealers or agents,
such underwriters, broker-dealers or agents may receive commissions in the form of discounts, concessions or commissions from
the selling shareholders or commissions from purchasers of the Common Shares for whom they may act as agent or to whom they may
sell as principal (which discounts, concessions or commissions as to particular underwriters, broker-dealers or agents may be
in excess of those customary in the types of transactions involved). In connection with sales of the Common Shares or otherwise,
the selling shareholders may enter into hedging transactions with broker-dealers, which may in turn engage in short sales of the
Common Shares in the course of hedging in positions they assume. The selling shareholders may also sell Common Shares short and
deliver Common Shares covered by this prospectus to close out short positions and to return borrowed shares in connection with
such short sales. The selling shareholders may also loan or pledge Common Shares to broker-dealers that in turn may sell such
shares. The selling shareholders may pledge or grant a security interest in some or all of the Warrants or Common Shares owned
by them and, if they default in the performance of their secured obligations, the pledgees or secured parties may offer and sell
the Common Shares from time to time pursuant to this prospectus or any amendment to this prospectus under Rule 424(b)(3) or other
applicable provision of the Securities Act of 1933, as amended, amending, if necessary, the list of selling shareholders to include
the pledgee, transferee or other successors in interest as selling shareholders under this prospectus. The selling shareholders
also may transfer and donate the Common Shares in other circumstances in which case the transferees, donees, pledgees or other
successors in interest will be the selling beneficial owners for purposes of this prospectus.
The
selling shareholders and any broker-dealer participating in the distribution of the Common Shares may be deemed to be “underwriters”
within the meaning of the Securities Act, and any commission paid, or any discounts or concessions allowed to, any such broker-dealer
may be deemed to be underwriting commissions or discounts under the Securities Act. At the time a particular offering of the Common
Shares is made, a prospectus supplement, if required, will be distributed which will set forth the aggregate amount of Common
Shares being offered and the terms of the offering, including the name or names of any broker-dealers or agents, any discounts,
commissions and other terms constituting compensation from the selling shareholders and any discounts, commissions or concessions
allowed or reallowed or paid to broker-dealers.
Under
the securities laws of some states, the Common Shares may be sold in such states only through registered or licensed brokers or
dealers. In addition, in some states the Common Shares may not be sold unless such shares have been registered or qualified for
sale in such state or an exemption from registration or qualification is available and is complied with. There can be no assurance
that any selling shareholder will sell any or all of the Common Shares registered pursuant to the registration statement, of which
this prospectus is a part.
The
selling shareholders and any other person participating in such distribution will be subject to applicable provisions of the Securities
Exchange Act of 1934, as amended (the “Exchange Act”), and the rules and regulations thereunder, including, without
limitation, Regulation M of the Exchange Act, which may limit the timing of purchases and sales of any of the Common Shares by
the selling shareholders and any other participating person. Regulation M may also restrict the ability of any person engaged
in the distribution of the Common Shares to engage in marketmaking activities with respect to the Common Shares. All of the foregoing
may affect the marketability of the Common Shares and the ability of any person or entity to engage in market-making activities
with respect to the Common Shares. We will pay all expenses of the registration of the Common Shares, estimated to be $100,240
in total, including, without limitation, Securities and Exchange Commission filing fees and expenses of compliance with state
securities or “blue sky” laws; provided, however, that a selling shareholder will pay all underwriting discounts and
selling commissions, if any. We will indemnify the selling shareholders against liabilities, including some liabilities under
the Securities Act, in accordance with the terms of the Warrants, securities purchase agreements and/or engagement letters, as
applicable, or the selling shareholders will be entitled to contribution. We may be indemnified by the selling shareholders against
civil liabilities, including liabilities under the Securities Act, that may arise from any written information furnished to us
by the selling shareholder specifically for use in this prospectus, in accordance with the related agreement, or we may be entitled
to contribution. Once sold under the registration statement of which this prospectus forms a part, the Common Shares will be freely
tradable in the hands of persons other than our affiliates.
The
securities offered by this prospectus have not been qualified in Canada and may not be offered or sold in Canada except
pursuant to a Canadian prospectus or prospectus exemption.
EXPENSES
OF THE OFFERING
The
following is a statement of estimated expenses to be incurred by us in connection with the registration of the securities registered
hereby, all of which will be borne by us. All amounts shown are estimates except the SEC registration fee.
SEC registration fee
|
|
$
|
240
|
|
Legal fees and expenses
|
|
$
|
60,000
|
|
Accountant’s fees and expenses
|
|
$
|
40,000
|
|
|
|
|
|
|
Total
|
|
$
|
100,240
|
|
LEGAL
MATTERS
The
validity of the Common Shares offered hereby will be passed upon for us by Norton Rose Fulbright Canada LLP.
EXPERTS
The
consolidated financial statements incorporated into this prospectus by reference to the Annual Report on Form 40-F for the year
ended December 31, 2020, as amended by Amendment No. 1 to Form 40-F filed with the SEC on March 29, 2021 have been so incorporated
in reliance on the report of PricewaterhouseCoopers LLP, an independent registered public accounting firm, given on the authority
of said firm as experts in auditing and accounting.
ENFORCEABILITY
OF CIVIL LIABILITIES
We
are a corporation incorporated under and governed by the CBCA. Many of our officers and directors, and some of the experts
named in this prospectus, are residents of Canada or elsewhere outside of the U.S., and a substantial portion of our assets
and the assets of such persons are located outside the U.S. As a result, it may be difficult for investors in the U.S. to effect
service of process within the U.S. upon such directors, officers and representatives of experts who are not residents of the U.S.
or to enforce against them judgments of a U.S. court predicated solely upon civil liability under U.S. federal securities laws
or the securities laws of any state within the U.S. We have been advised by our legal counsel, Norton Rose Fulbright Canada LLP, that a judgment of a U.S. court predicated solely upon civil liability under U.S. federal securities laws
would probably be enforceable in Canada if the U.S. court in which the judgment was obtained has a basis for jurisdiction in the
matter that would be recognized by a Canadian court for the same purposes. We have also been advised by Norton Rose Fulbright
Canada LLP, however, that there is substantial doubt as to whether an action could be brought in Canada
in the first instance on the basis of liability predicated solely upon U.S. federal securities laws.
WHERE
YOU CAN FIND MORE INFORMATION
We
file annual reports on Form 40-F with the SEC, and we furnish other documents, such as quarterly and current reports, proxy statements
and other information and documents that we file with the Canadian securities regulatory authorities, to the SEC, as required.
The materials we file with or furnish to the SEC are available to the public on the SEC’s Internet website at www.sec.gov.
Those filings are also available to the public on our corporate website at www.zentaris.com. Information contained
on our website is not a part of this prospectus and the inclusion of our website address in this prospectus is an
inactive textual reference only. As we are a Canadian issuer, we also file continuous disclosure documents with the Canadian securities
regulatory authorities, which documents are available on the System for Electronic Document Analysis and Retrieval website maintained by the Canadian Securities Administrators at www.sedar.com.
This
prospectus forms part of a registration statement that we filed with the SEC. The registration statement contains more
information than this prospectus regarding us and our Securities, including certain exhibits and schedules. You can obtain
a copy of the registration statement from the SEC at the address listed above or electronically at www.sec.gov.
DOCUMENTS
INCORPORATED BY REFERENCE
The
following documents have been filed with the various securities commissions or similar securities regulatory authorities in Canada
and are specifically incorporated by reference into, and form an integral part of, this prospectus:
|
●
|
our
Annual Report on Form 40-F for the fiscal year ended December 31, 2020, filed with the SEC on March 24, 2021 , as amended
by Amendment No. 1 to Form 40-F filed with the SEC on March 29, 2021;
|
|
●
|
a
Form 8-A12B/A filed with the SEC on May 5, 2019 to amend our previously filed Form 8-A12B filed on April 14, 2017;
|
|
●
|
the
Reports on Form 6-K furnished to the SEC on January 26, 2021, January 28, 2021, February 2, 2021, February 18, 2021, March 9, 2021 and March 11, 2021; and
|
|
●
|
to
the extent permitted by applicable securities law, any other documents which we elect to incorporate by reference into this
prospectus.
|
All
subsequent annual reports on Form 20-F or Form 40-F filed by us and all subsequent reports on Form 6-K furnished by us that are
identified by us as being incorporated by reference shall be deemed to be incorporated by reference into this prospectus
and deemed to be a part hereof after the date of this prospectus but before the termination of the offering by this prospectus.
We
will provide each person to whom this prospectus is delivered a copy of the information that has been incorporated into
this prospectus by reference but not delivered with the prospectus (except exhibits, unless they are specifically
incorporated into this prospectus by reference). You may obtain copies of these documents, at no cost, by writing or telephoning
us at:
Aeterna
Zentaris Inc.
Attention:
Investor Relations
315
Sigma Drive
Summerville,
South Carolina
USA,
29486
Tel.
(843) 900-3223
Any
statement contained in this Prospectus or in a document incorporated or deemed to be incorporated herein by reference shall be
deemed to be modified or superseded, for the purposes of this Prospectus, to the extent that a statement contained herein or in
any other subsequently filed document which also is or is deemed to be incorporated herein by reference modifies or supersedes
such statement. The modifying or superseding statement need not state that it has modified or superseded a prior statement or
include any other information set forth in the document that it modifies or supersedes. The making of a modifying or superseding
statement shall not be deemed an admission for any purposes that the modified or superseded statement, when made, constituted
a misrepresentation, an untrue statement of a material fact or an omission to state a material fact that is required to be stated
or that is necessary to make a statement not misleading in light of the circumstances in which it was made. Any statement so modified
or superseded shall not constitute a part of this Prospectus, except as so modified or superseded.
Upon
a new annual information form or annual report on Form 20-F or Form 40-F and the related audited annual consolidated financial
statements together with the auditors’ report thereon and management’s discussion and analysis related thereto being
filed by us with the applicable securities regulatory authorities during the currency of this Prospectus, the previous annual
information form or annual report on Form 20-F or Form 40-F, the previous audited annual consolidated financial statements and
all interim financial statements, annual and quarterly management’s discussion and analyses, material change reports and
business acquisition reports filed by us prior to the commencement of our financial year in which the new annual information form
or annual report on Form 20-F or Form 40-F was filed, no longer shall be deemed to be incorporated by reference into this Prospectus
for the purpose of future offers and sales of securities hereunder.
One
or more Prospectus Supplements containing the terms of an offering of securities hereunder and other information in relation to
such securities will be delivered to purchasers of such securities together with this Prospectus and shall be deemed to be incorporated
by reference into this Prospectus as of the date of such Prospectus Supplement solely for the purposes of the offering of the
securities covered by any such Prospectus Supplement.
A
Prospectus Supplement containing any additional or updated information that we elect to include therein will be delivered with
this Prospectus to purchasers of securities who purchase such securities after the filing of this Prospectus and shall be deemed
to be incorporated into this Prospectus as of the date of such Prospectus Supplement.
PART
II—INFORMATION NOT REQUIRED IN PROSPECTUS
ITEM
8. INDEMNIFICATION OF DIRECTORS AND OFFICERS
Under
Section 124 of the CBCA, the registrant may indemnify a present or
former director or officer of the registrant or another individual who acts or acted at the registrant’s request as a director
or officer, or an individual acting in a similar capacity, of another entity, against all costs, charges and expenses, including
an amount paid to settle an action or satisfy a judgment, reasonably incurred by the individual in respect of any civil, criminal,
administrative, investigative or other proceeding in which the individual is involved because of that association with the registrant
or other entity. The registrant may not indemnify an individual unless the individual (i) acted honestly and in good faith with
a view to the best interests of the registrant or, as the case may be, to the best interests of the other entity for which the
individual acted as director or officer or in a similar capacity at the registrant’s request, and (ii) in the case of a
criminal or administrative action or proceeding that is enforced by a monetary penalty, had reasonable grounds for believing that
his or her conduct was lawful. Such indemnification may be made in connection with an action by or on behalf of the registrant
or other entity to procure a judgment in its favor only with court approval. A director or officer is entitled to indemnification
from the registrant as a matter of right if he or she was not judged by the Court or other competent authority to have committed
any fault or omitted to do anything that he or she ought to have done and fulfilled the conditions set forth above. The registrant
may advance moneys to a director, officer or other individual for the costs, charges and expenses of a proceeding referred to
above. The individual shall repay the moneys if he or she does not fulfill the conditions set forth above to qualify for indemnification.
In
accordance with the provisions of the CBCA described above, the by-laws of the registrant provide that the registrant shall indemnify
a director or officer of the registrant, a former director or officer of the registrant or a person who acts or acted at the registrant’s
request as a director or officer of a body corporate of which the registrant is or was a shareholder or creditor, and his or her
heirs and legal representatives, against all costs, losses, charges and expenses, including an amount paid to settle an action
or satisfy a judgment, reasonably incurred by such person in respect of any civil, criminal or administrative action or proceeding
to which such person is made a party by reason of being or having been a director or officer of the registrant or such body corporate,
if: (a) the person acted honestly and in good faith with a view to the best interests of the registrant and (b) in the case of
criminal or administrative action or proceeding that is enforced by a monetary penalty, the person had reasonable grounds for
believing that their conduct was lawful. The registrant may indemnify from time to time any director or other person who has assumed
or is about to assume in the normal course of business any liability for the registrant or for any corporation controlled by the
registrant, and to secure such director or other person against any loss by the pledge of all or part of the movable or immovable
property of the registrant through the creation of a hypothec or any other real right in all or part of such property or in any
other manner.
The
by-laws of the registrant also provide that the registrant may, to the extent permitted by the CBCA, purchase and
maintain insurance for the benefit of any person referred to above against any such liability as the board of directors
of the registrant may from time to time determine.
Insofar
as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers or persons
controlling the registrant pursuant to the foregoing provisions, the registrant has been informed that in the opinion of the U.S.
Securities and Exchange Commission, such indemnification is against public policy as expressed in the Securities Act and is therefore
unenforceable.
The
registrant has also agreed to indemnify and save harmless the directors and its senior corporate officers as well as the managing
director of its German subsidiary pursuant to various Director and Officer Indemnification Agreements against certain charges,
damages, awards, settlements, liabilities, interest, judgments, fines, penalties, statutory obligations, professional fees and
retainers and other expenses of whatever nature or kind, provided that any such costs, charges, professional fees and other expenses
are reasonable (collectively, “Expenses”) and from and against all Expenses sustained or incurred by the indemnified
party as a result of serving as a director, officer or employee of the registrant in respect of any act, matter, deed or thing
whatsoever made, done, committed, permitted, omitted or acquiesced in by the indemnified party as a director, officer or employee
of the registrant. The form of Director and Officer Indemnification Agreement has been furnished to the SEC as Exhibit 99.1 to
the registrant’s Report on Form 6-K dated October 21, 2016.
ITEM
9. EXHIBITS
See
Exhibit Index following the signature pages of this registration statement.
ITEM
10. UNDERTAKINGS
(a)
The undersigned registrant hereby undertakes:
(1)
To file, during any period in which offers or sales are being made, a further post-effective amendment to this registration statement:
(i)
To include any prospectus required by section 10(a)(3) of the Securities Act of 1933;
(ii)
To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set
forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if
the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high
end of the estimated maximum offering range may be reflected in the form of prospectus filed with the SEC pursuant to Rule 424(b)
if, in the aggregate, the changes in volume and price represent no more than a 20 percent change in the maximum aggregate offering
price set forth in the “Calculation of Registration Fee” table in the effective registration statement; and
(iii)
To include any material information with respect to the plan of distribution not previously disclosed in the registration statement
or any material change to such information in the registration statement.
Provided,
however, that paragraphs (a)(1)(i), (a)(1)(ii) and (a)(1)(iii) of this section do not apply if the registration statement
is on Form S-3 or Form F-3 and the information required to be included in a post-effective amendment by those paragraphs is contained
in reports filed with or furnished to the SEC by the registrant pursuant to section 13 or section 15(d) of the Exchange Act that
are incorporated by reference in the registration statement, or is contained in a form of prospectus filed pursuant to Rule 424(b)
that is part of the registration statement.
(2)
That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall
be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at
that time shall be deemed to be the initial bona fide offering thereof.
(3)
To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold
at the termination of the offering.
(4)
To file a post-effective amendment to the registration statement to include any financial statements required by Item 8. A. of
Form 20-F at the start of any delayed offering or throughout a continuous offering. Financial statements and information otherwise
required by Section 10(a)(3) of the Securities Act of 1933 need not be furnished, provided, that the registrant includes
in the prospectus, by means of a post-effective amendment, financial statements required pursuant to this paragraph (a) (4) and
other information necessary to ensure that all other information in the prospectus is at least as current as the date of those
financial statements. Notwithstanding the foregoing, with respect to registration statements on Form F-3, a post-effective amendment
need not be filed to include financial statements and information required by Section 10(a)(3) of the Securities Act of 1933 or
Rule 3-19 of Regulation S-X if such financial statements and information are contained in periodic reports filed with or furnished
to the SEC by the registrant pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated
by reference in the Form F-3.
(5)
That, for the purpose of determining liability under the Securities Act to any purchaser:
(i)
Each prospectus filed by the registrant pursuant to Rule 424(b)(3) shall be deemed to be part of the registration statement as
of the date the filed prospectus was deemed part of and included in the registration statement; and
(ii)
Each prospectus required to be filed pursuant to Rule 424(b)(2), (b)(5), or (b)(7) as part of a registration statement in reliance
on Rule 430B relating to an offering made pursuant to Rule 415(a)(l)(i), (vii), or (x) for the purpose of providing the information
required by section 10(a) of the Securities Act of 1933 shall be deemed to be part of and included in the registration statement
as of the earlier of the date such form of prospectus is first used after effectiveness or the date of the first contract of sale
of securities in the offering described in the prospectus. As provided in Rule 430B, for liability purposes of the issuer and
any person that is at that date an underwriter, such date shall be deemed to be a new effective date of the registration statement
relating to the securities in the registration statement to which that prospectus relates, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof. Provided, however, that no statement
made in a registration statement or prospectus that is part of the registration statement or made in a document incorporated or
deemed incorporated by reference into the registration statement or prospectus that is part of the registration statement will,
as to a purchaser with a time of contract of sale prior to such effective date, supersede or modify any statement that was made
in the registration statement or prospectus that was part of the registration statement or made in any such document immediately
prior to such effective date.
(6)
That, for the purpose of determining liability of the registrant under the Securities Act of 1933 to any purchaser in the initial
distribution of the securities:
The
undersigned registrant undertakes that in a primary offering of securities of the undersigned registrant pursuant to this registration
statement, regardless of the underwriting method used to sell the securities to the purchaser, if the securities are offered or
sold to such purchaser by means of any of the following communications, the undersigned registrant will be a seller to the purchaser
and will be considered to offer or sell such securities to such purchaser:
(i)
Any preliminary prospectus or prospectus of the undersigned registrant relating to the offering required to be filed pursuant
to Rule 424;
(ii)
Any free writing prospectus relating to the offering prepared by or on behalf of the undersigned registrant or used or referred
to by the undersigned registrant;
(iii)
The portion of any other free writing prospectus relating to the offering containing material information about the undersigned
registrant or its securities provided by or on behalf of the undersigned registrant; and
(b)
Any other communication that is an offer in the offering made by the undersigned registrant to the purchaser.
(c)
The undersigned registrant hereby undertakes that, for purposes of determining any liability under the Securities Act of 1933,
each filing of the registrant’s annual report pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable,
each filing of an employee benefit plan’s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated
by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offering
therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.
(d)
The undersigned registrant hereby undertakes that:
(i)
For purposes of determining any liability under the Securities Act of 1933, the information omitted from the form of prospectus
filed as part of this registration statement in reliance upon Rule 430A and contained in the form of prospectus filed by the registrant
pursuant to Rule 424(b)(1) or (4) or 497(h) under the Securities Act of 1933 shall be deemed to be part of the registration statement
as of the time it was declared effective.
(ii)
For the purpose of determining any liability under the Securities Act of 1933, each post-effective amendment that contains a form
of prospectus shall be deemed to be a new registration statement relating to the securities offered therein, and the offering
of such securities at that time shall be deemed to be the initial bona fide offering thereof.
(e)
Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and
controlling persons of the registrant pursuant to the foregoing provisions, or otherwise, the registrant has been advised that
in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act of 1933 and is, therefore,
unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant
of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action,
suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered,
the registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court
of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities
Act of 1933 and will be governed by the final adjudication of such issue.
EXHIBIT
INDEX
Exhibit
Index
4.1
|
Restated
Certificate of Incorporation and Restated Articles of Incorporation of the Registrant (incorporated by reference to Exhibit 99.2
to the Registrant’s report on Form 6-K furnished to the Commission on May 25, 2011)
|
4.2
|
Certificate
of Amendment and Articles of Amendment of the Registrant (incorporated by reference to Exhibit 99.2 to the Registrant’s report
on Form 6-K furnished to the Commission on October 3, 2012)
|
4.3
|
Certificate
of Amendment and Articles of Amendment of the Registrant (incorporated by reference to Exhibit 99.1 to the Registrant’s report
on Form 6-K furnished to the Commission on November 17, 2015)
|
4.4
|
Amended
and Restated By-Law One of the Registrant (incorporated by reference to Exhibit 1.3 of the Registrant’s Annual Report on Form
20-F for the financial year ended December 31, 2012 filed with the Commission on March 22, 2013)
|
4.5
|
Amended
and Restated Shareholder Rights Plan Agreement between the Registrant and Computershare Trust Company of Canada, as Rights Agent,
dated as of May 8, 2019 (incorporated by reference to Exhibit 99.2 to the Registrant’s report on Form 6-K furnished to the
Commission on May 9. 2019)
|
4.6
|
Form
of Underwriter Warrant (incorporated by reference to Exhibit 99.2 of the Registrant’s report on Form 6-K furnished to
the Commission on February 18, 2021)
|
5.1*
|
Opinion
of Norton Rose Fulbright Canada LLP
|
23.1*
|
Consent
of Norton Rose Fulbright Canada LLP (included in Exhibit 5.1)
|
23.2
|
Consent
of PricewaterhouseCoopers LLP (incorporated by reference to Exhibit 99.8 of Amendment No. 1 to the Company’s Annual Report
on Form 40-F filed with the Commission on March 29, 2021)
|
24.1*
|
Power
of Attorney
|
*
Previously filed.
SIGNATURES
Pursuant
to the requirements of the Securities Act, the registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing and has duly caused this Amendment No. 1 to Registration Statement on Form F-3 to be signed
on its behalf by the undersigned, thereunto duly authorized, in the City of Charleston, South Carolina, on April 5, 2021.
|
AETERNA
ZENTARIS INC.
|
|
|
|
By:
|
/s/
Klaus Paulini, PhD
|
|
Name:
|
Klaus
Paulini, PhD
|
|
Title:
|
President
and Chief Executive Officer
|
SIGNATURES
Pursuant
to the requirements of the Securities Act, this Amendment No. 1 to Registration Statement has been signed by the following
persons in the capacities indicated below on April 5, 2021.
Signature
|
|
Title
|
|
|
|
/s/
Klaus Paulini, PhD
|
|
President,
Chief Executive Officer (Principal
|
Klaus
Paulini, PhD
|
|
Executive
Officer) and Director
|
|
|
|
/s/
Leslie Auld
|
|
Senior
Vice President, Chief Financial Officer
|
Leslie
Auld
|
|
(Principal
Financial Officer and Principal Accounting Officer)
|
|
|
|
*
|
|
Director
and Chair of the Board
|
Carolyn
Egbert
|
|
|
|
|
|
*
|
|
Director
|
Pierre-Yves
Desbiens
|
|
|
|
|
|
*
|
|
Director
|
Peter
G. Edwards
|
|
|
|
|
|
*
|
|
Director
|
Gilles
Gagnon
|
|
|
*By:
|
/s/
Klaus Paulini, PhD
|
|
Name:
|
Klaus
Paulini, PhD
|
|
Title:
|
Attorney-in-fact
|
|
AUTHORIZED
REPRESENTATIVE
Pursuant
to the requirements of Section 6(a) of the Securities Act of 1933, the undersigned has signed this Amendment No. 1 to Registration
Statement on Form F-3, solely in the capacity of the duly authorized representative of Aeterna Zentaris Inc. in the United States,
on April 5, 2021.
|
AETERNA
ZENTARIS INC.
|
|
|
|
By:
|
/s/
Klaus Paulini, PhD
|
|
Name:
|
Klaus
Paulini, PhD
|
|
Title:
|
Authorized
Signatory
|
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