RNS Number:6883O
CeNeS Pharmaceuticals PLC
14 August 2003


                   CENES PHARMACEUTICALS PLC ("the Company")


                                HOLDING IN COMPANY



The Company was informed on 14 August 2003 that Elan International Services
Limited no longer holds any ordinary shares of 1p each in the capital of the
Company.


The Company was also informed on 14 August 2003 that the Marlborough Special
Situations Fund now has an interest in 8,000,000 ordinary shares of 1p each in
the capital of the Company representing 3.79 per cent. of the issued share
capital of the Company following a sale of 500,000 ordinary shares of 1p each.
These shares are held by HSBC Global Custody Nominees Limited a/c 764685.



Further information

Neil Clark, CeNeS Pharmaceuticals plc                    01223 266 466











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