Smith+Nephew unveils expanded Sports Medicine portfolio to enable
biological healing at AAOS 2024 Annual Meeting
12 February 2024
Smith+Nephew (LSE:SN, NYSE:SNN), the global medical technology
company, announces the premiere of its newly acquired CARTIHEAL◊
AGILI-C◊ Cartilage Repair Implant alongside the REGENETEN◊
Bioinductive Implant at the AAOS Annual Meeting, demonstrating its
leadership with products that enable biological healing for Sports
Medicine. Backed by impressive clinical evidence, both technologies
are transforming the way healthcare professionals treat soft tissue
repair and helping improve patient outcomes versus the current
standard of care.1,2
CARTIHEAL AGILI-C◊ Cartilage Repair Implant – a simple,
single surgery to repair cartilage and restore boneThe
CARTIHEAL AGILI-C implant is an accessible, one-step treatment for
osteochondral (bone and cartilage) lesions that does not require
donor tissue. It is indicated to treat a broad patient population,
including traumatic, osteoarthritic and the approximately 700,0003
individuals who receive cartilage repair annually in the US. The
implant has demonstrated proven superiority with twice the pain
reduction1 versus the current standard of care* and has the
potential to transform cartilage repair outcomes.
During its development, the CARTIHEAL AGILI-C implant received
breakthrough designation status by the United States Food and Drug
Administration – expedited review and approval for a product that
could provide more effective treatment than existing alternatives
and in the best interest of patients. It received premarket
approval in 2022 and is now commercially available for sale in the
US.
“I’ve already used the CARTIHEAL AGILI-C implant on a range of
patients and have been very impressed with the clinical results,”
said Sabrina M. Strickland, MD, orthopaedic surgeon at the Hospital
for Special Surgery in New York City. “What is most exciting is
that this technology represents a paradigm shift in cartilage
repair and bone restoration where a lot of patients that didn’t
previously have a good option can now receive treatment.”
REGENETEN Bioinductive Implant – changing the game in
rotator cuff repair and expanding applications With more
than 100,000 procedures completed globally since its introduction
in 2014, the REGENETEN Bioinductive Implant has had a massive
impact, offering a potentially better solution for more than 1
million4 people having surgery for tendon injuries each year. The
collagen-based implant supports the body’s natural healing response
to facilitate the formation of new tendon-like tissue to
biologically augment the existing tendon and change the course of
disease progression.2,5-10
A recently completed randomized controlled trial published in
December 2023, concluded that at one-year, re-tear rates for medium
and large full-thickness rotator cuff tears repaired and augmented
with the REGENETEN Bioinductive Implant were reduced by 68%.3
REGENETEN Bioinductive Implant for Rotator Cuff
Repair
The REGENETEN Bioinductive Implant is similarly redefining
healing potential for Achilles injuries when used to augment
insertional or midsubstance Achilles repair. The implant creates an
environment that is conducive to healing and induces tendon-like
tissue growth.†,‡,5 When coupling the unique properties of
the REGENETEN Bioinductive Implant with Smith+Nephew’s new
procedural offerings for Achilles injuries, the solution is
unmatched within the Foot and Ankle segment.
REGENETEN Bioinductive Implant for Achilles Tendon
Repair
“As a leader in Sports Medicine, we are committed to bringing
emerging technologies that address unmet clinical needs to our
customers and their patients,” said Scott Schaffner, President
Sports Medicine, Smith+Nephew. “Both REGENETEN and CARTIHEAL
AGILI-C implants have the opportunity to set new benchmarks for
standard of care across multiple joint repair indications and
deliver better patient outcomes.”
To learn more about Smith+Nephew’s offerings that enable
biological healing including the CARTIHEAL AGILI-C Cartilage Repair
Implant and the REGENETEN Bioinductive Implant, please visit the
Smith+Nephew booth (#5469) at the American Academy of Orthopaedic
Surgeons 2024 Annual Meeting from February 12-16 in San Francisco,
CA.
- ends -
Enquiries
MediaDavid
Snyder
+1
978-749-1440Smith+Nephew |
|
|
|
|
|
References
- Altschuler N, Zaslav KR, Di Matteo B, et al. Aragonite-Based
Scaffold Versus Microfracture and Debridement for the Treatment of
Knee Chondral and Osteochondral Lesions: Results of a Multicenter
Randomized Controlled Trial. Am J Sports Med. 2023;51(4):957-967.
doi:10.1177/03635465231151252
- Ruiz Ibán MA, Navlet MG, Marco SM, et al. Augmentation of
a transosseous equivalent repair in posterosuperior non-acute
rotator cuff tears with a bioinductive collagen implant decreases
the re-tear rate at one year. A randomised controlled trial.
Arthroscopy. Published online 12/27/2023.
- Medtech 360, Sports Medicine Devices, Market Analysis, US,
2018, Millennium Research Group, Inc.
- iData Research. Rotator cuff repair and reconstruction market
size, share and trends analysis (2023). Available at:
https://idataresearch.com/product/rotator-cuff-repair-reconstruction-market-size-share-and-trends-analysis-global-2023-2029-medsuite-includes-grafts-allografts-xenograft-synthetic-and-1-more/#.
Accessed December 19, 2023.
- Bokor DJ, Sonnabend D, Deady L, et al. Evidence of healing of
partial-thickness rotator cuff tears following arthroscopic
augmentation with a collagen implant: a 2-year MRI follow-up.
Muscles, Ligaments Tendons J. 2016;6(1):16-25.
- Schlegel TF, Abrams JS, Bushnell BD, Brock JL, Ho CP.
Radiologic and clinical evaluation of a bioabsorbable collagen
implant to treat partial-thickness tears: a prospective multicenter
study. J Shoulder Elbow Surg. 2018 27(2):242-251.
- Van Kampen C, Arnoczky S, Parks P, et al. Tissue-engineered
augmentation of a rotator cuff tendon using a reconstituted
collagen scaffold: a histological evaluation in sheep. Muscles
Ligaments Tendons J. 2013;3(3):229-235.
- Arnoczky SP, Bishai SK, Schofield B, et al. Histologic
Evaluation of Biopsy Specimens Obtained After Rotator Cuff Repair
Augmented With a Highly Porous Collagen Implant. Arthroscopy.
2017;33(2):278-283
- Bokor DJ, Sonnabend DH, Deady L, et al. Healing of
partial-thickness rotator cuff tears following arthroscopic
augmentation with a highly porous collagen implant: a 5-year
clinical and MRI follow-up. Muscles, Ligaments Tendons J.
2019;9(3):338-347.
- McElvany MD, McGoldrick E, Gee AO, Neradilek MB, Matsen FA,
3rd. Rotator cuff repair: published evidence on factors associated
with repair integrity and clinical outcome. Am J Sports Med.
2015;43(2):491-500.
* microfracture and/or debridement† The REGENETEN Bioinductive
implant is cleared for use on any tendon where there is not
substantial loss of tendon tissue. REGENETEN Bone Anchors are only
indicated for use in rotator cuff repair. Published clinical
outcomes are for rotator cuff.‡ As demonstrated in vivo
About Smith+NephewSmith+Nephew is a portfolio
medical technology company focused on the repair, regeneration and
replacement of soft and hard tissue. We exist to restore people’s
bodies and their self-belief by using technology to take the limits
off living. We call this purpose ‘Life Unlimited’. Our 19,000
employees deliver this mission every day, making a difference to
patients’ lives through the excellence of our product
portfolio, and the invention and application of new technologies
across our three global business units of Orthopaedics, Sports
Medicine & ENT and Advanced Wound Management.
Founded in Hull, UK, in 1856, we now operate in more than 100
countries, and generated annual sales of $5.2 billion in 2022.
Smith+Nephew is a constituent of the FTSE100 (LSE:SN, NYSE:SNN).
The terms ‘Group’ and ‘Smith+Nephew’ are used to refer to Smith
& Nephew plc and its consolidated subsidiaries, unless the
context requires otherwise.
For more information about Smith+Nephew, please
visit www.smith-nephew.com and follow us
on X, LinkedIn, Instagram or Facebook.
Forward-looking StatementsThis document may
contain forward-looking statements that may or may not prove
accurate. For example, statements regarding expected revenue growth
and trading margins, market trends and our product pipeline are
forward-looking statements. Phrases such as "aim", "plan",
"intend", "anticipate", "well-placed", "believe", "estimate",
"expect", "target", "consider" and similar expressions are
generally intended to identify forward-looking statements.
Forward-looking statements involve known and unknown risks,
uncertainties and other important factors that could cause actual
results to differ materially from what is expressed or implied by
the statements. For Smith+Nephew, these factors include: risks
related to the impact of Covid, such as the depth and longevity of
its impact, government actions and other restrictive measures taken
in response, material delays and cancellations of elective
procedures, reduced procedure capacity at medical facilities,
restricted access for sales representatives to medical facilities,
or our ability to execute business continuity plans as a result of
Covid; economic and financial conditions in the markets we serve,
especially those affecting healthcare providers, payers and
customers (including, without limitation, as a result of Covid);
price levels for established and innovative medical devices;
developments in medical technology; regulatory approvals,
reimbursement decisions or other government actions; product
defects or recalls or other problems with quality management
systems or failure to comply with related regulations; litigation
relating to patent or other claims; legal and financial compliance
risks and related investigative, remedial or enforcement actions;
disruption to our supply chain or operations or those of our
suppliers (including, without limitation, as a result of Covid);
competition for qualified personnel; strategic actions, including
acquisitions and dispositions, our success in performing due
diligence, valuing and integrating acquired businesses; disruption
that may result from transactions or other changes we make in our
business plans or organisation to adapt to market developments;
relationships with healthcare professionals; reliance on
information technology and cybersecurity; disruptions due to
natural disasters, weather and climate change related events;
changes in customer and other stakeholder sustainability
expectations; changes in taxation regulations; effects of foreign
exchange volatility; and numerous other matters that affect us or
our markets, including those of a political, economic, business,
competitive or reputational nature. Please refer to the documents
that Smith+Nephew has filed with the U.S. Securities and Exchange
Commission under the U.S. Securities Exchange Act of 1934, as
amended, including Smith+Nephew's most recent annual report on Form
20-F, which is available on the SEC’s website at www.
sec.gov, for a discussion of certain of these factors. Any
forward-looking statement is based on information available to
Smith+Nephew as of the date of the statement. All written or oral
forward-looking statements attributable to Smith+Nephew are
qualified by this caution. Smith+Nephew does not undertake any
obligation to update or revise any forward-looking statement to
reflect any change in circumstances or in Smith+Nephew's
expectations.
◊ Trademark of Smith+Nephew. Certain marks registered in US
Patent and Trademark Office.
Smith and Nephew (TG:NPW1)
Historical Stock Chart
From Nov 2024 to Dec 2024
Smith and Nephew (TG:NPW1)
Historical Stock Chart
From Dec 2023 to Dec 2024