FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Wengel Kathryn E		 2. Issuer Name and Ticker or Trading Symbol

JOHNSON & JOHNSON [ JNJ ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
EVP, Chief GSC Officer
(Last)          (First)          (Middle)

ONE JOHNSON & JOHNSON PLAZA		 3. Date of Earliest Transaction (MM/DD/YYYY)

6/10/2022
(Street)

NEW BRUNSWICK, NJ 08933
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 6/10/2022  M  40000.0000 A$72.5400 111310.8735 D  
Common Stock 6/10/2022  S  100.0000 D$173.0010 (1)111210.8735 D  
Common Stock 6/10/2022  S  174.0000 D$173.0010 (1)111036.8735 D  
Common Stock 6/10/2022  S  6600.0000 D$173.0010 (1)104436.8735 D  
Common Stock 6/10/2022  S  33126.0000 D$173.0010 (1)71310.8735 D  
Common Stock         50.0000 (2)I By 401k 
Common Stock         281.0000 (3)I By ESOP 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Options (Right to Buy) $72.5400 6/10/2022  M     40000.0000  1/17/2016 1/13/2023 Common Stock 40000.0000 $0.0000 16410.0000 D  
Explanation of Responses:
(1) This transaction was executed in multiple trades at prices ranging from 173.00 to 173.02 . The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide, upon request, to the SEC staff, the issuer, or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
(2) Includes shares accrued due to dividend reinvestment in the Johnson & Johnson Stock Fund under the Johnson & Johnson Savings Plan as of the Plan's most recent reporting date (5/31/2022)
(3) Shares held by ESOP under the Johnson & Johnson Savings Plan as of the Plan's most recent reporting date (5/31/2022)

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Wengel Kathryn E
ONE JOHNSON & JOHNSON PLAZA
NEW BRUNSWICK, NJ 08933

EVP, Chief GSC Officer
Signatures
Raavi K. Deol, as attorney-in-fact for Kathryn E. Wengel6/14/2022
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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