FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Khan Samina
2. Date of Event Requiring Statement (MM/DD/YYYY)
2/7/2022 

3. Issuer Name and Ticker or Trading Symbol

REATA PHARMACEUTICALS INC [RETA]
(Last)        (First)        (Middle)

5320 LEGACY DRIVE
4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                          _____ 10% Owner
___X___ Officer (give title below)        _____ Other (specify below)
SVP, Chief Medical Officer /
(Street)

PLANO, TX 75024      

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
 

6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Class A common stock 35149 (1)D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy)  (2)7/7/2030 Class A common stock 20000 $155.64 D  
Employee Stock Option (right to buy)  (3)1/4/2031 Class A common stock 10100 $121.29 D  
Employee Stock Option (right to buy)  (4)1/3/2032 Class A common stock 50000 $27.32 D  

Explanation of Responses:
(1) The shares represent 924 shares of Class A stock; 1,875 Restricted Stock Units (RSU), which vest in equal installments on April 26, 2022, April 26, 2023, and April 26, 2024, subject to continued service through each vesting date; 5,100 RSUs, which vest in equal installments on March 6, 2022, March 6, 2023, March 6, 2024, and March 6, 2025, subject to continued service through each vesting date; 2,250 RSUs, which vest in equal installments on September 1, 2022, September 1, 2023, and September 1, 2024, subject to continued service through each vesting date; and 25,000 RSUs, which vest in equal installments on March 6, 2023, March 6, 2024, March 6, 2025, and March 6, 2026, subject to continued service through each vesting date.
(2) The options vest 25% on July 7, 2021 and in 12 equal quarterly installments thereafter, subject to continued service through each vesting date.
(3) The options vest in sixteen equal quarterly installments beginning on April 4, 2021, subject to continued service through each vesting date.
(4) The options vest in sixteen equal quarterly installments beginning on April 3, 2022, subject to continued service through each vesting date.

Remarks:
Exhibit List: Exhibit 24 - Power of Attorney

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Khan Samina
5320 LEGACY DRIVE
PLANO, TX 75024


SVP, Chief Medical Officer

Signatures
/s/ Tracy Herson, attorney-in-fact2/7/2022
**Signature of Reporting PersonDate

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