Gilead, Galapagos Halt Trial of Pulmonary-Fibrosis Treatment
February 10 2021 - 9:40AM
Dow Jones News
By Matt Grossman
Galapagos NV and Gilead Sciences Inc. said Wednesday that they
have halted their Phase 3 trials studying the use of ziritaxestat,
an autotaxin inhibitor, as a treatment for patients with idiopathic
pulmonary fibrosis.
The decision is based on a recommendation from the trial's
independent data-monitoring committee, the companies said. The
committee concluded that the drug's benefit-risk profile did not
support continuing the study.
The Phase 3 program consisted of two trials that aimed to enroll
1,500 patients combined. Patients were randomized to receive
varying dose amounts of ziritaxestat or a placebo while they
continued standard-of-care background treatment.
Write to Matt Grossman at matt.grossman@wsj.com
(END) Dow Jones Newswires
February 10, 2021 09:25 ET (14:25 GMT)
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