Affymetrix to Host Conference Call on April 21, 2005 to Announce First Quarter 2005 Results SANTA CLARA, Calif., April 14 /PRNewswire-FirstCall/ -- Affymetrix, Inc. (NASDAQ:AFFX) today announced that it will release results for the first quarter of 2005 after close of the stock market on Thursday, April 21, 2005. Company management will also host a conference call at 2:00 p.m. PDT on April 21 to discuss first quarter 2005 results and provide financial guidance for the second quarter of 2005. The dial-in number for domestic callers will be 800-884-5695 and for international callers will be 617-786-2960. The passcode is 25840962. To listen to a live webcast of the conference call, find the "Investors" link in the "Resources for" drop-down menu on http://www.affymetrix.com/. A telephonic replay of the conference call will be available from two hours after the call until 5:00 p.m. PDT on April 28, 2005. The replay number for domestic callers will be 888-286-8010 and for international callers will be 617-801-6888. The passcode for both domestic and international callers is 77047580. An archived webcast of the conference call will be available under the "Investors" section of the company's website at http://www.affymetrix.com/. The conference call, replay and webcast are open to all interested parties. About Affymetrix: Affymetrix scientists invented the world's first high-density microarray in 1989 and began selling the first commercial microarray in 1994. Since then, Affymetrix GeneChip(R) technology has become the industry standard in molecular biology research. Affymetrix technology is used by the world's top pharmaceutical, diagnostic and biotechnology companies as well as leading academic, government and not-for-profit research institutes. More than 1,200 systems have been installed around the world and nearly 3,000 peer-reviewed papers have been published using the technology. Affymetrix' patented photolithographic manufacturing process provides the most information capacity available today on an array, enabling researchers to use a whole-genome approach to analyze the relationship between genetics and health. Affymetrix is headquartered in Santa Clara, Calif., with manufacturing facilities in Sacramento, Calif., and Bedford, Mass. The company maintains important sales and marketing operations in Europe and Asia and has about 900 employees worldwide. DATASOURCE: Affymetrix, Inc. CONTACT: Doug Farrell, Vice President of Investor Relations of Affymetrix, Inc., +1-408-731-5285 Web site: http://www.affymetrix.com/

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