By Michael Calia 

U.S. Bancorp said its profit edged up 2.2% in the most recent quarter as its revenue and average total loans grew, though a key measure of lending profitability narrowed.

Earnings and revenue beat Wall Street estimates.

The bank posted earnings of $1.49 billion, up from $1.46 billion in the prior-year period. On a per-share basis, earnings rose to 79 cents from 76 cents. One-time items tied to equity investments and accruals for legal matters boosted earnings by one cent a share in the latest period.

Revenue at the Minneapolis-based bank rose 5.7% to $5.17 billion.

Analysts had expected 77 cents a share in earnings and $5.01 billion in revenue, according to Thomson Reuters.

Average total loans rose by 5.9%.

Net interest margin, which is an important measure of lending profitability, fell to 3.14% from 3.4% a year earlier on lower reinvestment rates on investment securities and lower rates on new loans.

The bank had posted growth in profit and loans recently, although it faces a tough environment in which low interest rates limit interest income.

Shares were inactive premarket and are off slightly over the past 12 months.

Write to Michael Calia at michael.calia@wsj.com

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