BSD Medical Files Response to FDA Questions on BSD-2000 PMA Submission Following Meeting with FDA
July 31 2007 - 11:00AM
PR Newswire (US)
SALT LAKE CITY, July 31 /PRNewswire-FirstCall/ -- BSD Medical Corp.
today announced that the Company has filed the response to FDA's
questions on the Premarket Approval Application (PMA) submitted for
the BSD-2000 Deep Hyperthermia System. The company has done
extensive planning to ensure that the information included in the
response addresses the questions asked by FDA. On June 27, 2007,
BSD met with FDA to clarify FDA's questions prior to filing the
company's response, in order to ensure that the company's response
adequately addressed FDA's questions. Because the company's
response was not filed until after the European Society for
Hyperthermic Oncology (ESHO) conference, which was held on June
14-26, 2007, BSD was able to include in the FDA submission the
12-year follow-up survival data from the Dutch Deep Hyperthermia
Trial, which is the pivotal study BSD is using to support the
submission for PMA approval of the BSD-2000 Hyperthermia System.
The long-term survival data from this study were presented at the
ESHO conference. One of the primary concerns about the viability of
new therapies is their durability. The 12-year follow-up data from
the study showed that the addition of hyperthermia to radiation
therapy for the treatment of advanced cervical cancer resulted in
long-term significant improvement in both local control and
survival, without an increase in toxicity. The overall survival at
12-year follow-up was 37% in the hyperthermia and radiation therapy
group and 20% in the radiation therapy only group (p=0.04). Local
control of the cancer also remained better after 12-year follow-up
in the hyperthermia and radiation therapy group, 56%, versus 36% in
the radiation therapy only group (p=0.02). After 12 years of
follow-up, the late toxicity from radiation therapy was not
significantly increased by the addition of hyperthermia. These data
demonstrated that the improvement seen from the addition of
hyperthermia to radiation therapy is durable over a 12-year
follow-up period. BSD Medical Corp. is the leading developer of
systems used to deliver hyperthermia therapy for the treatment of
cancer. Hyperthermia therapy is used to kill cancer directly and
increase the effectiveness of companion radiation treatments.
Research has also shown highly promising results from the use of
hyperthermia therapy in combination with some chemotherapy agents,
as well as for tumor reduction prior to surgery. For further
information about BSD Medical visit the company's website at
http://www.bsdmedical.com/. Statements contained in this press
release that are not historical facts are forward-looking
statements, as defined in the Private Securities Litigation Reform
Act of 1995. All forward-looking statements are subject to risks
and uncertainties detailed in the Company's filings with the
Securities and Exchange Commission. DATASOURCE: BSD Medical Corp.
CONTACT: Hyrum A. Mead of BSD Medical Corp., +1-801-972-5555, fax,
+1-801-972-5930, Web site: http://www.bsdmedical.com/
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