As filed with the Securities and Exchange Commission
on February 19, 2025
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
ORCHESTRA BIOMED HOLDINGS, INC.
(Exact name of registrant as specified in its
charter)
| Delaware |
|
92-2038755 |
(State or other jurisdiction of
incorporation
or organization) |
|
(I.R.S. Employer
Identification No.) |
150 Union Square Drive
New Hope, Pennsylvania 18928
(Address of Principal Executive Offices) (Zip
Code)
Orchestra BioMed Holdings, Inc. 2023 Equity
Incentive Plan
(Full titles of the plans)
David P. Hochman
Chief Executive Officer
150 Union Square Drive
New Hope, PA 18928
(215) 862-5797
(Name, address and telephone number, including
area code, of agent for service)
Copies to:
Yariv Katz, Esq.
Keith Pisani, Esq.
Paul Hastings LLP
200 Park Avenue
New York, NY 10016
(212) 318-6000
Indicate by check mark whether the registrant is a large accelerated
filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See the definitions of
“large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth
company” in Rule 12b-2 of the Exchange Act.
| Large accelerated filer |
¨ |
Accelerated filer |
¨ |
| |
|
|
|
| Non-accelerated filer |
x |
Smaller reporting company |
x |
| |
|
|
|
| |
|
Emerging growth company |
x |
If an emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
to Section 7(a)(2)(B) of the Securities Act. ¨
EXPLANATORY NOTE; INCORPORATION BY REFERENCE
OF CONTENTS OF
REGISTRATION STATEMENTS ON FORM S-8
Pursuant to General Instruction E of Form S-8,
Orchestra BioMed Holdings, Inc. (the “Registrant” or the “Company”) is filing this Registration Statement with
the Securities and Exchange Commission (the “SEC”) to register 1,833,333 additional shares of common stock, par value $0.0001
per share (“Common Stock”), of the Registrant reserved for issuance under the Orchestra BioMed Holdings, Inc. 2023 Equity
Incentive Plan (the “2023 Plan”) resulting from an automatic annual increase as of January 1, 2025. This Registration Statement
hereby incorporates by reference the contents of the Registrant’s previous Registration Statements on Form S-8 filed with the SEC on April 3, 2023 (File No. 333-271092) and March 27, 2024 (File No. 333-278285).
PART I
INFORMATION REQUIRED IN THE SECTION 10(a)
PROSPECTUS
The information called for
in Part I of Form S-8 is not being filed with or included in this Form S-8 (by incorporation by reference or otherwise)
in accordance with the rules and regulations of the SEC.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
| ITEM 3. |
INCORPORATION OF DOCUMENTS BY REFERENCE. |
The following documents filed by the Registrant
with the SEC are hereby incorporated by reference into this Registration Statement:
| (a) |
The Registrant’s Annual Report on Form 10-K for the year ended December 31, 2023, filed with the SEC on March 27, 2024; |
| |
|
| (b) |
The Registrant’s Quarterly Reports on Form 10-Q for the quarter ended March 31, 2024, filed with the SEC on May 13, 2024, for the quarter ended June 30, 2024, filed with the SEC on August 12, 2024, and for the quarter ended September 30, 2024, filed with the SEC on November 12, 2024; |
| |
|
| (c) |
The Registrant’s Current Reports on Form 8-K, filed with SEC on March 29, 2024, June 20, 2024, July 30, 2024 (excluding the information furnished under Item 7.01), August 12, 2024 and February 5, 2025 (excluding the information furnished under Item 7.01); and |
| |
|
| (d) |
The description of the Registrant’s Common Stock contained in Exhibit 4.16 to the Annual Report on Form 10-K for the year ended December 31, 2023, filed with the SEC on March 27, 2024, including any amendment or reports filed for the purpose of updating such description. |
All other reports and other documents subsequently
filed by the Registrant pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Exchange Act prior to the filing of a post-effective
amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold,
shall be deemed to be incorporated by reference into this Registration Statement and to be a part of this Registration Statement from
the date of the filing of such reports and documents, except as to any portion of any future current report furnished under Items 2.02
or 7.01 of Form 8-K that is not deemed filed under such provisions.
For the purposes of this Registration Statement,
any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or
superseded to the extent that a statement contained herein or in any other subsequently filed document that also is or is deemed to be
incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed,
except as so modified or superseded, to constitute a part of this Registration Statement.
You should rely only on the information provided
or incorporated by reference in this Registration Statement or any related prospectus. The Registrant has not authorized anyone to provide
you with different information. You should not assume that the information in this Registration Statement or any related prospectus is
accurate as of any date other than the date on the front of the document.
You may contact the Registrant in writing or orally
to request copies of the above-referenced filings, without charge (excluding exhibits to such documents unless such exhibits are specifically
incorporated by reference into the information incorporated into this Registration Statement). Requests for such information should be
directed to:
Orchestra BioMed Holdings, Inc.
150 Union Square Drive
New Hope, PA 18938
Attn: Chief Executive Officer
ITEM 8. EXHIBITS.
SIGNATURES
Pursuant to the requirements of the Securities
Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for
filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in city of New York, State of New York, on February 19, 2025.
| |
ORCHESTRA BIOMED HOLDINGS, INC. |
| |
|
| |
By: |
/s/ David P. Hochman |
| |
Name: |
David P. Hochman |
| |
Title: |
Chief Executive Officer |
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, that
each person whose signature appears below constitutes and appoints David P. Hochman and Andrew L. Taylor, and each or any one of them,
as his or her true and lawful attorneys-in-fact and agent, with full power of substitution and resubstitution, for him or her and in his
or her name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this
Registration Statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities
and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform
each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he might
or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them, or their or his substitutes
or substitute, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities
Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.
| SIGNATURE |
|
TITLE |
|
DATE |
| |
|
|
|
|
| /s/ David P. Hochman |
|
Chief Executive Officer, Chairperson and Director |
|
February 19, 2025 |
| David P. Hochman |
|
(Principal Executive Officer) |
|
|
| |
|
|
|
|
| /s/ Andrew L. Taylor |
|
Chief Financial Officer |
|
February 19, 2025 |
| Andrew L. Taylor |
|
(Principal Financial Officer) |
|
|
| |
|
|
|
|
| /s/ Joshua Aiello |
|
Corporate Controller |
|
February 19, 2025 |
| Joshua Aiello |
|
(Principal Accounting Officer) |
|
|
| |
|
|
|
|
| /s/ Jason Aryeh |
|
Director |
|
February 19, 2025 |
| Jason Aryeh |
|
|
|
|
| |
|
|
|
|
| /s/ Chris Cleary |
|
Director |
|
February 19, 2025 |
| Chris Cleary |
|
|
|
|
| |
|
|
|
|
| /s/ Pamela A. Connealy |
|
Director |
|
February 19, 2025 |
| Pamela A. Connealy |
|
|
|
|
| |
|
|
|
|
| /s/ Eric S. Fain, M.D. |
|
Director |
|
February 19, 2025 |
| Eric S. Fain, M.D. |
|
|
|
|
| |
|
|
|
|
| /s/ David Pacitti |
|
Director |
|
February 19, 2025 |
| David Pacitti |
|
|
|
|
| |
|
|
|
|
| /s/ Darren R. Sherman |
|
Chief Operating Officer and Director |
|
February 19, 2025 |
| Darren R. Sherman |
|
|
|
|
Exhibit 5.1
February 19, 2025
Orchestra BioMed Holdings, Inc.
150 Union Square Drive
New Hope, PA 18938
Re: Registration Statement on Form S-8
Ladies and Gentlemen:
We have acted as counsel to Orchestra BioMed Holdings, Inc., a Delaware
corporation (the “Company”), in connection with the preparation of the registration statement on Form S-8
to be filed by the Company with the U.S. Securities and Exchange Commission (the “Commission”) on the date
hereof (the “Registration Statement”) to effect registration under the Securities Act of 1933, as amended
(the “Securities Act”), of 1,833,333 shares (the “Shares”) of the Company’s
common stock, $0.0001 par value per share (“Common Stock”), reserved for awards available for future issuance
under the Orchestra BioMed Holdings, Inc. 2023 Equity Incentive Plan (the “2023 Plan”).
As such counsel and for purposes of our opinion set forth below, we
have examined and relied upon originals or copies, certified or otherwise identified to our satisfaction, of such documents, resolutions,
certificates and instruments of the Company and corporate records furnished to us by the Company, and have reviewed certificates of public
officials, statutes, records and such other instruments and documents as we have deemed necessary or appropriate as a basis for the opinion
set forth below, including, without limitation:
| (i) | the Registration Statement; |
| (ii) | the Certificate of Incorporation of the Company (the “Certificate of Incorporation”), as certified as of
February 19, 2025 by the Office of the Secretary of State of the State of Delaware; |
| (iii) | the Amended and Restated Bylaws of the Company as presently in effect, as certified by an officer of the Company on February 19, 2025; |
| (iv) | the 2023 Plan and the forms of award agreements related thereto; |
| (v) | a certificate, dated as of February 19, 2025, from the Office of the Secretary of State of the State of Delaware, certifying as to
the existence and good standing of the Company in the State of Delaware (the “Good Standing Certificate”); |
| (vi) | the resolutions adopted by the board of directors of the Health Sciences Acquisitions Corporation 2 (“HSAC2”),
the resolutions adopted by the board of directors of the Company and the resolutions adopted by the Compensation Committee of the Company
regarding the 2023 Plan, and other matters related thereto, as certified by an officer of the Company on February 19, 2025; |
Orchestra BioMed Holdings, Inc.
February 19, 2025
Page 2
| (vii) | the resolutions adopted by the shareholders of HSAC2 regarding the 2023 Plan, and other matters related thereto, as certified by an
officer of the Company on February 19, 2025; |
| (viii) | the agreement and plan of merger, dated as of July 4, 2022, by and among HSAC2, HSAC Olympus Merger Sub, Inc., and Orchestra BioMed,
Inc., as amended. |
In addition to the foregoing, we have made such investigations of law
as we have deemed necessary or appropriate as a basis for the opinion set forth in this opinion letter.
In such examination and in rendering the opinion expressed below, we
have assumed, without independent investigation or verification: (i) the genuineness of all signatures on all agreements, instruments,
corporate records, certificates and other documents submitted to us; (ii) the authenticity and completeness of all agreements, instruments,
corporate records, certificates and other documents submitted to us as originals; (iii) that all agreements, instruments, corporate
records, certificates and other documents submitted to us as certified, electronic, facsimile, conformed, photostatic or other copies
conform to originals thereof, and that such originals are authentic and complete; (iv) the legal capacity, competency and authority
of all individuals executing all agreements, instruments, corporate records, certificates and other documents; (v) the due authorization,
execution and delivery of all agreements, instruments, corporate records, certificates and other documents by all parties thereto (other
than the Company); (vi) that no documents submitted to us have been amended or terminated orally or in writing except as has been
disclosed to us in writing; (vii) that the statements contained in the certificates and comparable documents of public officials,
officers and representatives of the Company and other persons on which we have relied for the purposes of this opinion letter are true
and correct on and as of the date hereof; (viii) that there has not been any change in the good standing status of the Company from
that reported in the Good Standing Certificate; and (ix) that each of the officers and directors of the Company has properly exercised
his or her fiduciary duties. As to all questions of fact material to this opinion letter, and as to the materiality of any fact or other
matter referred to herein, we have relied (without independent investigation or verification) upon representations and certificates or
comparable documents of officers and representatives of the Company. We have also assumed that the individual issuances, grants, awards
or grants of purchase rights under the 2023 Plan will be duly authorized by all necessary corporate action of the Company and duly issued,
granted or awarded and exercised in accordance with the requirements of law, the 2023 Plan and the agreements, forms of instrument, awards
and grants duly adopted thereunder. We have also assumed that upon the issuance of any Shares, the total number of shares of Common Stock
issued and outstanding will not exceed the total number of shares of Common Stock that the Company is then authorized to issue under the
Certificate of Incorporation.
Based upon the foregoing, and in reliance thereon, and subject to the
assumptions, limitations, qualifications and exceptions set forth herein, we are of the opinion that the Shares are duly authorized and,
when issued and sold as described in the Registration Statement and in accordance with the 2023 Plan and the applicable award agreements
or forms of instrument evidencing purchase rights thereunder (including the receipt by the Company of the full consideration therefor),
will be validly issued, fully paid and nonassessable.
Without limiting any of the other assumptions, limitations, qualifications
and exceptions stated elsewhere herein, we express no opinion with regard to the applicability or effect of the laws of any jurisdiction
other than the General Corporation Law of the State of Delaware, as in effect on the date of this opinion letter.
Orchestra BioMed Holdings, Inc.
February 19, 2025
Page 3
This opinion letter deals only with the specified legal issues expressly
addressed herein, and you should not infer any opinion that is not explicitly stated herein from any matter addressed in this opinion
letter.
This opinion letter is rendered solely in connection with the preparation
and filing of the Registration Statement. This opinion letter is rendered as of the date hereof, and we assume no obligation to advise
you or any other person with regard to any change after the date hereof in the circumstances or the law that may bear on the matters set
forth herein even if the change may affect the legal analysis or a legal conclusion or other matters in this opinion letter.
We hereby consent to the filing of this opinion letter as Exhibit 5.1
to the Registration Statement. In giving such consent, we do not hereby admit that we are within the category of persons whose consent
is required under Section 7 of the Securities Act or the rules or regulations of the Commission thereunder.
Very truly yours,
/s/ Paul Hastings LLP
Exhibit 23.1
Consent of Independent Registered Public Accounting
Firm
We consent to the incorporation by reference in the Registration Statement
(Form S-8) pertaining to the Orchestra BioMed Holdings, Inc. 2023 Equity Incentive Plan of Orchestra BioMed Holdings, Inc. of our report
dated March 27, 2024, with respect to the consolidated financial statements of Orchestra BioMed Holdings, Inc. included in its Annual
Report (Form 10-K) for the year ended December 31, 2023, filed with the Securities and Exchange Commission.
/s/ Ernst & Young LLP
Philadelphia, Pennsylvania
February 19, 2025
Exhibit 107
Calculation of Filing Fee Tables
Form S-8
(Form Type)
Orchestra BioMed Holdings, Inc.
(Exact Name of Registrant as Specified in its
Charter)
Table 1: Newly Registered Securities
| Security
Type |
Security
Class Title |
Fee
Calculation
Rule |
Amount
Registered(1) |
Proposed
Maximum
Offering
Price Per
Unit |
Maximum
Aggregate
Offering
Price |
Fee
Rate |
Amount
of
Registration
Fee |
| Equity |
Common
Stock, $0.0001 par value per share, “Common Stock”) reserved for issuance under the Orchestra BioMed Holdings,
Inc. 2023 Equity Incentive Plan (the “2023 Plan”) |
457(c)
and (h) |
1,833,333(2) |
$5.37(3) |
$9,844,998.21(3) |
0.00015310 |
$1,507.27 |
| Total
Offering Amounts |
|
$9,844,998.21 |
|
$1,507.27 |
| Total
Fee Offsets |
|
|
|
– |
| Net
Fee Due |
|
|
|
$1,507.27 |
| (1) | Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the “Securities
Act”), this Registration Statement shall also cover any additional shares of Common Stock
that become issuable under the 2023 Plan by reason of any stock dividend, stock split, recapitalization
or other similar transaction effected without receipt of consideration that increases the number of
the Registrant’s outstanding shares of Common Stock. |
| | |
| (2) | Represents the additional shares of Common Stock reserved for issuance under the 2023 Plan resulting from an automatic
annual increase as of January 1, 2025. |
| | |
| (3) | Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(c) and Rule 457(h) of the Securities
Act. The proposed maximum offering price per share and the proposed maximum aggregate offering price are calculated based
on $5.37 per share, the average of the high and low price of the Common Stock on the Nasdaq Global Market on February 12,
2025 (such date being within five business days prior to the date that this registration statement was filed with the U.S.
Securities and Exchange Commission). |
Orchestra BioMed (NASDAQ:OBIO)
Historical Stock Chart
From Feb 2025 to Mar 2025
Orchestra BioMed (NASDAQ:OBIO)
Historical Stock Chart
From Mar 2024 to Mar 2025
