FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      
1. Name and Address of Reporting Person * Zelibor Thomas Edward 2. Issuer Name and Ticker or Trading Symbol Lightwave Logic, Inc. [ LWLG ] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable)__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Chair of Board of Directors
(Last)         (First)         (Middle)
369 INVERNESS PARKWAY, SUITE 350
3. Date of Earliest Transaction (MM/DD/YYYY)
11/19/2021
(Street)
ENGLEWOOD, CO 80112
(City)       (State)       (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)
 
6. Individual or Joint/Group Filing (Check Applicable Line) _X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock  11/19/2021    M    500000  A $1.30  550124  D   
Common Stock  11/19/2021    S(1)    75046  D $14.57 (2) 475078  D   
Common Stock  11/19/2021    S(1)    49106  D $14.59 (3) 425972  D   
Common Stock  11/20/2021    S(1)    101373  D $14.04 (4) 324599  D   
Common Stock  11/20/2021    S(1)    14475  D $13.53  310124  D   
Common Stock                 400  I  By Spouse 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)  $1.30  11/19/2021    M        500000    (5) 4/30/2022  Common Stock  500000  $0  1120000  D   

Explanation of Responses:
(1)  Shares sold in connection with exercise of company stock options to pay the exercise price for the exercise of the grant (cashless exercise) and related taxes.
(2)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions. Share prices on this transaction ranged from $14.50 to $15.01. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote to this Form 4.
(3)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions. Share prices on this transaction ranged from $14.45 to $14.81. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote to this Form 4.
(4)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions. Shares price on this transaction ranged from $13.38 to $14.75. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote to this Form 4.
(5)  On 5/1/2012 the registrant granted the reporting person an option to purchase up to 500,000 shares of company stock that vest pursuant to the following schedule: one hundred twenty five thousand (125,000) options vest immediately and the remaining options vest in three (3) equal quarterly installments of one hundred twenty five thousand (125,000) options per quarter.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Zelibor Thomas Edward
369 INVERNESS PARKWAY
SUITE 350
ENGLEWOOD, CO 80112
X
Chair of Board of Directors

Signatures
/s/ James S. Marcelli, Attorney-in-fact for Thomas E. Zelibor 11/23/2021
**Signature of Reporting Person Date
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