BERLIN, Aug. 26, 2019 /PRNewswire/ -- At EUROISMAR 2019
(https://conference.euroismar2019.org), Bruker Corporation (Nasdaq:
BRKR) today announced the world's first 1.2 GHz
high-resolution, protein nuclear magnetic resonance (NMR) data. Two
1.2 GHz superconducting magnets have now reached full field at
Bruker's Swiss magnet factory, setting the world record for stable,
homogeneous NMR magnets for high-resolution and solid-state protein
NMR applications in structural biology and for the study of
intrinsically disordered proteins (IDPs).
At EUROISMAR 2019, Bruker and its scientific collaborators are
presenting 1.2 GHz high-resolution NMR data that has been acquired
using a new 1.2 GHz 3 mm triple-inverse TCI
CryoProbe. Bruker's unique 1.2 GHz ultra-high field NMR
magnets utilize a novel hybrid design with high-temperature
superconductor (HTS) inserts inside advanced, low-temperature
superconductor (LTS) outserts, which together provide the extremely
demanding stability and homogeneity for high-resolution protein
NMR.
Professors Lucia Banci and
Claudio Luchinat at the University of Florence, Italy, are expected to be the first
customers to receive a 1.2 GHz NMR spectrometer, once further
systems development and factory testing has been completed, a
process that is expected to take several more months. After
initial data acquisition of CERM test samples on one of the 1.2 GHz
systems, they stated: "At Bruker's UHF facility in Switzerland, high resolution spectra have been
acquired on alpha-synuclein, which is an intrinsically disordered
protein that has been linked to diseases such as Alzheimer's and
Parkinson's. In addition, we have also been able to review first
1.2 GHz NMR spectra of a protein which is associated with several
types of cancer. Without a doubt, the improved resolution of
the 1.2 GHz instrument – made possible by the increased
dispersion at high magnetic fields – will help to advance important
fields of research, such as structural biology. We look
forward to receiving the 1.2 GHz NMR spectrometer in our laboratory
once final developments and factory evaluation have been
completed."
Dr. Falko Busse, Group President
of Bruker BioSpin, said: "The new 1.2 GHz system is a technological
revolution that will enable new molecular and cell biology
discoveries. We value the trust our ultra-high field NMR
customers place in us, and we are proud to have achieved this
further milestone of generating the world's first high-resolution
protein NMR data at 1.2 GHz. While we are not yet completely
finished with all developments for the new 1.2 GHz system, our
recent rapid progress is a testament to our commitment to
innovation, and to working collaboratively with our customers to
develop enabling scientific capabilities."
Similar to the previously announced Ascend 1.1 GHz magnet, the
Ascend 1.2 GHz hybrid HTS/LTS magnet is a
standard-bore (54 mm), two-story magnet system with drift and
homogeneity specifications similar to Bruker's existing 900 MHz and
1 GHz ultra-high field NMR magnets, ensuring compatibility with a
range of NMR probe types and spectrometer accessories.
Bruker's Ascend™ 1.2 GHz NMR
magnets leverage the same advanced conductor and magnet
technologies for winding, jointing, force management, quench
protection, low drift and high homogeneity that were developed
successfully for the Ascend 1.1 GHz magnet that was announced as a
product at ENC 2019.
About Bruker Corporation (Nasdaq: BRKR)
Bruker is enabling scientists to make breakthrough discoveries
and develop new applications that improve the quality of human
life. Bruker's high-performance scientific instruments and
high-value analytical and diagnostic solutions enable scientists to
explore life and materials at molecular, cellular and microscopic
levels. In close cooperation with our customers, Bruker is enabling
innovation, improved productivity and customer success in life
science molecular research, in applied and pharma applications, in
microscopy and nanoanalysis, and in industrial applications, as
well as in cell biology, preclinical imaging, clinical phenomics
and proteomics research and clinical microbiology. For more
information, please visit: www.bruker.com.
Investor Contact:
Miroslava
Minkova
Director, Investor Relations & Corporate Development
T: +1 (978) 663-3660 x1479
E: Investor.Relations@bruker.com
Media Contact:
Thorsten
Thiel, Ph.D.
Bruker BioSpin VP of Group Marketing
T: +49 (721) 5161–6500
E: thorsten.thiel@bruker.com
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SOURCE Bruker Corporation