ALKS Alkermes PLC

FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES                                                                                   
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940                       

1. Name and Address of Reporting Person * MITCHELL PAUL J	2. Issuer Name and Ticker or Trading Symbol Alkermes plc. [ ALKS ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director                    _____ 10% Owner _____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle) CONNAUGHT HOUSE, 1 BURLINGTON ROAD	3. Date of Earliest Transaction (MM/DD/YYYY) 10/1/2020
(Street) DUBLIN 4 IRELAND  (City)        (State)        (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) _X _ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares	10/1/2020		M(1)		20000	A	$14.92	27000	I	The Paul J. Mitchell Trust (2)
Ordinary Shares	10/1/2020		S(3)		20000	D	$16.6131 (4)	7000	I	The Paul J. Mitchell Trust (2)
Ordinary Shares								8000	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Non Qualified Stock Option (Right to Buy)	$14.92	10/1/2020		M (1)			20000	(5)	10/5/2020	Ordinary Shares	20000	$0	0	D

Explanation of Responses:
(1)	This option exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on 5/6/2019.
(2)	The reporting person and his wife are co-trustees of The Paul J. Mitchell Trust and the reporting person is also a beneficiary of The Paul J. Mitchell Trust originally established on November 19, 2014 and amended and restated on September 8, 2017 ("The Paul J. Mitchell Trust").
(3)	This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on 5/6/2019.
(4)	The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $16.48 to $16.76. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.
(5)	These options are fully vested in accordance with their terms.

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
MITCHELL PAUL J CONNAUGHT HOUSE 1 BURLINGTON ROAD DUBLIN 4 IRELAND	X

Signatures
/s/ Shantale Greenson, attorney-in-fact for Paul J. Mitchell		10/2/2020
**Signature of Reporting Person		Date