Senseonics Holdings, Inc. (NYSE-MKT:SENS), a medical technology company focused on the development and commercialization of a long-term, implantable continuous glucose monitoring (CGM) system for people with diabetes, today announced that the company has been added to the Russell 2000® Index following the reconstitution of Russell Investment Group’s family of US indexes, which occurred after the markets closed, June 24th, 2016.

FTSE Russell determines membership for its Russell indexes by objective, market-capitalization rankings and style attributes and membership in the Russell 2000® Index remains in place for at least one year. Russell indexes are widely used by investment managers and institutional investors for index funds and as benchmarks for active investment strategies.

About Senseonics

Senseonics Holdings, Inc. is a medical technology company focused on the design, development and commercialization of glucose monitoring products designed to help people with diabetes confidently live their lives with ease. Our first generation continuous glucose monitoring (CGM) system, Eversense®, includes a small sensor, smart transmitter and mobile application. Based on fluorescence sensing technology, the sensor is designed to be inserted subcutaneously and communicate with the smart transmitter to wirelessly transmit glucose levels to a mobile device. After insertion, the sensor is designed to continually and accurately measure glucose levels. For more information on Senseonics, please visit www.senseonics.com.

About FTSE Russell

FTSE Russell is a global index leader and data provider that provides innovative benchmarking, analytics and data solutions for investors worldwide. FTSE Russell calculates thousands of indexes that measure and benchmark markets and asset classes in more than 70 countries, covering 98% of the investable market globally. FTSE Russell is wholly owned by London Stock Exchange Group. For more information, please visit www.ftserussell.com.

Senseonics Holdings, Inc.R. Don Elsey, 301-556-1602Chief Financial Officerdon.elsey@senseonics.com

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