HAYWARD, Calif., March 30, 2015 /PRNewswire/ -- Confirming
its investment in the area of brain inflammation and
neuroprotection, CreAgri welcomes German University of Darmstadt's
announcement on the launch of the research project NeurOliv with
the support of the German government.
Directed at developing functional foods for patients with
Alzheimer's or just as way to protect and prevent the brain from
aging, the NeurOliv consortium research leverages the
anti-inflammatory and antioxidant activities of olive polyphenols,
especially hydroxytyrosol.
In 2013, at the International Symposium on Functional Foods and
Bioactive Compounds held at Kyoto's Prefectural University,
Hidrox®—CreAgri's proprietary formulation of olive polyphenols—was
proposed to support the management of neuroinflammation and
other inflammation-based brain dysfunctions. Last summer, CreAgri
cooperated with the University of California
San Francisco and the University of Naples to sponsor an international scientific
meeting on neuroprotection, "Biophysics of Amyloids and Prions,"
which took place in May 2014 at
Naples' (Italy) Castel dell'Ovo.
The meeting featured the world's 100 major researchers in the
area of brain health, including Nobel Laureate Prof. Stanley B. Prusiner and small molecules design
expert Dr. William De Grado. CreAgri
delivered a keynote presentation by its CEO Dr. Roberto Crea on hydroxytyrosol and brain
health.
CreAgri, Inc., a leader in the production of olive polyphenols
for health and wellness, has been at the forefront of initiatives
proposing the use of hydroxytyrosol to provide support to people
affected by neurological dysfunctions since its first process
discovery for the mass production of hydroxytyrosol from the juice
of olives. Indeed, already in 2001 a small unpublished study
conducted at the University of California San
Francisco with patients suffering of HIV-induced dementia
reported that hydroxytyrosol (Olivenol/Hidrox®) had an effect on
cognitive activity. Hidrox® also showed significant
anti-inflammatory activity in brain cells in an in vitro study
carried out in collaboration with Sunnyvale's Parkinson's Institute, aimed at
confirming Hidrox®'s ability to forestall neuroinflammation in a
Parkinson's model.
More recently CreAgri's R&D in neuroprotective applications
with Hidrox® have advanced at Mount Sinai Hospital's research
collaboration supporting the use of Hidrox® to quench inflammation
and to reduce oligomerization of tau proteins, as well as the
formation of amyloid plaques. Similarly, an animal model study
conducted by Boston-based Phylonix
targeting the cytotoxicity of agents that can cause chronic
demyelinating lesions similar to those present in multiple
sclerosis confirmed the protective effect of Hidrox® against
cuprizone-induced demyelization.
"Our commitment to develop further applications of Hidrox® in
neuroprotection through collaborative efforts with premier research
institutions is of primary importance; consumers and patients alike
should expect new and powerful products for health and wellness
directed at making their life healthier and more productive,"
declares Dr. Roberto Crea, founder
and lead scientist in the discovery of the anti-inflammatory
activity of hydroxytyrosol more than ten years ago.
"For more than 5 million of Americans and their families
Alzheimer's is a daily, devastating reality," adds Dr. Crea.
"Current pharmacological solutions do not provide satisfactory
outcomes; compounds such as Hidrox® may prove to be a natural and
effective adjunctive tool in the options available to physicians
today to manage this debilitating, mind-robbing condition.
CreAgri's research confirms beyond doubts a role for Hidrox® and
olive polyphenols in neuroprotection."
About HIDROX®
HIDROX® is CREAGRI's trademarked
hydroxytyrosol formulation, a powerful polyphenol scientifically
recognized for its anti-inflammatory and antioxidant properties and
efficacy in heart and joint health. GRAS
certified, HIDROX® has been subjected to the most
comprehensive set of clinical, safety and efficacy
tests. HIDROX® is also covered by the largest
number of international patents for applications that include
hydroxytyrosol and olive polyphenol.
About CREAGRI
CREAGRI® Inc., a California company, is the leading
manufacturer of HIDROX® a proprietary
hydroxytyrosol-rich ingredient. Its goal is to promote health and
wellness by creating superior natural products that strike a
balance between nature and technology. The Company develops
science-based processes that are environmentally friendly and
compatible with sustainable agricultural practices.
For media inquiries please contact Paolo Pontoniere,
VP - Corporate Communications, 510-732-6478
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SOURCE CreAgri, Inc.