By Sara Sjolin, MarketWatch

LONDON (MarketWatch) -- Standard Chartered PLC led the FTSE 100 index lower on Wednesday after disappointing comments on full-year profit, while the broader market tracked losses in the rest of Europe, where fears of tapering in the U.S. dented the investing mood.

The benchmark index lost 0.3% to close at 6,509.97 for a fourth straight day in negative territory.

Shares of Standard Chartered slid 6.5% after the bank in a pre-close trading update said difficult market conditions are expected the rest of the year and that income for 2013 will be broadly flat on 2012. Analysts at Credit Suisse said the statement was disappointing, with weaker revenues, higher costs and higher impairments.

Other banks were also lower. HSBC Holdings PLC (HSBC) gave up 1.3%, Barclays PLC (BCS) fell 1.3% and Lloyds Banking Group PLC dropped 1.6%.

The broader losses in London came as investors feared the U.S. Federal Reserve could move closer to cutting its monthly asset purchases after the ADP job report showed that private-sector employers added a stronger-than-expected 215,000 jobs to the economy in November. Cheap central-bank liquidity has been one of the reasons stock markets globally have climbed to multiyear highs in 2013.

Data were also in the spotlight in the U.K. as the Markit/CIPS services purchasing managers' index showed the sector continued to expand in November. The index printed at 60 last month, down from October's multiyear high of 62.5, but above the 50-level that separates expansion from contraction.

"The data add to indications that the economy is set to grow by at least 1.0% in the fourth quarter, enjoying its strongest period of GDP growth since 2007," said Chris Williamson, chief economist at Markit, in a note.

"Job creation is surging as firms take on staff in the face of increasingly buoyant order books. Furthermore, with growth of new business hitting a record high in November, output and employment growth could reaccelerate again in December," he added.

Among other notable movers in London, Sage Group PLC jumped 7.3% after the software firm raised its dividend by 6% and said it is on track to meet its organic revenue-growth target in 2015.

On a sector basis, mining firms showed the biggest positive moves. Shares of Rio Tinto PLC (RIO) added 2%, BHP Billiton PLC (BHP) gained 0.9% and Randgold Resources Ltd. put on 0.6%. Metals prices were mostly higher.

Shares of Tesco PLC lost 0.5% after the supermarkets chain said it is performing in line with market expectations, but that same-store sales declined in the U.K. in the third quarter.

Reckitt Benckiser Group PLC slipped 1% after UBS cut the consumer-products firm to sell from buy. The analysts said they see low earnings growth until 2015.

More European news from MarketWatch

Sage Group on track to meet growth views

Deutsche Bank sees DAX at 11,000 in 2014

Germany's economy isn't as strong as people believe

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