ENZ Enzo Biochem Inc

FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES                                                                                   
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940                       

1. Name and Address of Reporting Person * HARBERT MANAGEMENT CORP	2. Issuer Name and Ticker or Trading Symbol ENZO BIOCHEM INC [ ENZ ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director                    __X__ 10% Owner _____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle) 2100 THIRD AVENUE NORTH, SUITE 600	3. Date of Earliest Transaction (MM/DD/YYYY) 3/15/2021
(Street) BIRMINGHAM, AL 35203 (City)        (State)        (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) ___ Form filed by One Reporting Person _ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock, $0.01 par value ("Common Stock")	3/15/2021		S		100000	D	$4.75	5520681	I	See footnote (1)
Common Stock	3/15/2021		S		44768	D	$5.00	5475913	I	See footnote (1)
Common Stock	3/16/2021		S		200000	D	$4.70	5275913	I	See footnote (1)
Common Stock	3/16/2021		S		100000	D	$4.539	5175913	I	See footnote (1)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

(1)

The securities reported herein are held by Harbert Discovery Fund, LP (the "Discovery Fund") and Harbert Discovery Co-Investment Fund I, LP (the "Discovery Co-Investment Fund" and together with the Discovery Fund, the "Funds"). Harbert Discovery Fund GP, LLC ( the "Discovery Fund GP") is the general partner of the Discovery Fund, and Harbert Discovery Co-Investment Fund I GP, LLC is the general partner of the Discovery Co-Investment Fund (and together with Harbert Discovery Fund GP, the "Fund GPs"). Harbert Fund Advisors, Inc. is the investment adviser to the Funds. Harbert Management Corporation ("HMC") is the managing member of the Fund GPs. Jack Bryant is a Senior Advisor to the Discovery Fund, and a Vice President and Senior Managing Director of HMC. Kenan Lucas is the managing director and portfolio manager of the Funds. Raymond Harbert is the controlling shareholder, Chairman and Chief Executive Officer of HMC.

Remarks: Remarks: Each Reporting Person disclaims beneficial ownership in the securities reported on this Form 4 except to the extent of its or his pecuniary interest, if any, therein, and this report shall not be deemed to be an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
HARBERT MANAGEMENT CORP 2100 THIRD AVENUE NORTH SUITE 600 BIRMINGHAM, AL 35203		X
Harbert Discovery Fund, LP HARBERT DISCOVERY FUND GP, LLC 2100 THIRD AVENUE NORTH, SUITE 600 BIRMINGHAM, AL 35203		X
HARBERT DISCOVERY FUND GP, LLC 2100 THIRD AVENUE NORTH SUITE 600 BIRMINGHAM, AL 35203		X
HARBERT DISCOVERY CO-INVESTMENT FUND I, LP 2100 THIRD AVENUE NORTH SUITE 600 BIRMINGHAM, AL 35203		X
HARBERT DISCOVERY CO-INVESTMENT FUND I GP, LLC 2100 THIRD AVENUE NORTH SUITE 600 BIRMINGHAM, AL 35203		X
HARBERT FUND ADVISORS, INC. 2100 THIRD AVENUE NORTH SUITE 600 BIRMINGHAM, AL 35203		X
BRYANT JOHN F. C/O HARBERT MANAGEMENT CORPORATION 2100 THIRD AVENUE NORTH, SUITE 600 BIRMINGHAM, AL 35203		X
LUCAS KENAN C/O HARBERT MANAGEMENT CORPORATION 2100 THIRD AVENUE NORTH, SUITE 600 BIRMINGHAM, AL 35203		X
HARBERT RAYMOND J 2100 THIRD AVENUE NORTH SUITE 600 BIRMINGHAM, AL 35203		X

Signatures
Harbert Discovery Fund, LP, By: Harbert Discovery Fund GP, LLC, its General Partner, By: Harbert Management Corporation, its Managing Member, By: /s/ John McCullough, Executive Vice President and General Counsel		3/17/2021
**Signature of Reporting Person		Date
Harbert Discovery Fund GP, LLC, By: Harbert Management Corporation, its Managing Member, By: /s/ John McCullough, Executive Vice President and General Counsel		3/17/2021
**Signature of Reporting Person		Date
Harbert Discovery Co-Investment Fund I, LP, By: Harbert Discovery Co-Investment Fund I GP, LLC, its General Partner, By: Harbert Management Corporation, its Managing Member, By: /s/ John McCullough, Executive Vice President and General Counsel		3/17/2021
**Signature of Reporting Person		Date
Harbert Discovery Co-Investment Fund I GP, LLC, By: Harbert Management Corporation, its Managing Member, By: /s/ John McCullough, Executive Vice President and General Counsel		3/17/2021
**Signature of Reporting Person		Date
Harbert Fund Advisors, Inc., By: /s/ John McCullough, Executive Vice President and General Counsel		3/17/2021
**Signature of Reporting Person		Date
Harbert Management Corporation, By: /s/ John McCullough, Executive Vice President and General Counsel		3/17/2021
**Signature of Reporting Person		Date
/s/ Jack Bryant		3/17/2021
**Signature of Reporting Person		Date
/s/ Kenan Lucas		3/17/2021
**Signature of Reporting Person		Date
/s/ Raymond Harbert		3/17/2021
**Signature of Reporting Person		Date