NetworkNewsWire Editorial
Coverage: Double 2001 levels,
Americans spent over $36 billion on vitamins and nutritional
supplements in 2016, contributing to a global dietary supplements
market expected to exceed $220 billion by the year 2022 (http://nnw.fm/z8Bh1, http://nnw.fm/qARU7). A noteworthy characteristic of
products within this booming sector is bio-absorbability. In order
for the body to utilize vitamins and minerals, they must
disintegrate and be quickly released. Otherwise, they are simply
excreted, rendering them ineffectual. A recent study revealed that
over half of encapsulated micronutrients didn’t disintegrate within
the time needed for effective absorption (http://nnw.fm/12CAq), demonstrating a sizable
underserved need within the multi-billion-dollar industry.
Lexaria Bioscience Corp. (CSE: LXX) (OTCQB:
LXRP) (LXRP
Profile) has developed and patented a
cost-effective lipophilic technology that addresses this issue,
serving as a delivery platform for all cannabinoids, fat soluble
vitamins, non-steroidal anti-inflammatory pain medications
(“NSAIDs”), and even nicotine. With proven efficacy for improved
taste, rapidity, and delivery of bioactive compounds, Lexaria is
positioned to license its technology to tobacco giants such as
Philip Morris International, Inc.
(NYSE: PM) and
British American Tobacco PLC
(NYSE: BTI), as well as
cannabinoid biopharmaceutical companies like GW
Pharmaceuticals PLC (NASDAQ: GWPH) and major drug
companies such as Pfizer, Inc. (PFE).
Adding to its portfolio of 19 international patent applications
filed encompassing 44 countries, Lexaria
Bioscience Corp. (CSE: LXX) (OTCQB: LXRP) earlier this
week announced that it has received from the United States Patent
and Trademark Office (“USPTO”) a new Notice of Allowance that
applies to the delivery of all applied-for active pharmacological
ingredients (“APIs”). As was the case with Lexaria’s existing
non-psychoactive cannabinoid patent, the company expects formal
patent issuance within three to four months, which is expected to
provide protection until at least 2035.
The issuance of the patent will enable Lexaria to accelerate its
technology out-licensing activities in several key markets. The
irony is that this R&D that originated in the cannabis is now
finding use in delivery of NSAIDs, vitamins and even nicotine.
“This wide-ranging patent allowance from the USPTO exceeds our
expectations. This vastly expanded intellectual property protection
will enable us to aggressively pursue new business opportunities in
2018 such as what could be the world’s first nicotine edibles for
the smokeless tobacco industry, or enhanced products for
NSAID-derived pain management, as well as in the rapidly growing
cannabis market,” Lexaria CEO Chris Bunka stated in the press
release announcing the news (http://nnw.fm/2iPIn).
According to the CDC, 36.5 million adults in the U.S. currently
smoke tobacco, while 16 million live with a smoking-related
disease. The U.S. FDA earlier this year submitted a proposal to
reduce nicotine levels in cigarettes to non-addictive levels in an
effort to significantly reduce the effects of tobacco-related
diseases. As such, leading tobacco companies are pursuing
marketable alternatives to their combustible offerings, and Lexaria
is uniquely positioned to capture a share of this mammoth market
with technology allows that for the infusion of nicotine molecules
within a wide range of edible food ingredients or capsules.
Notably, current forms of nicotine delivery have mostly failed.
The development of readily absorbed nicotine-infused edible
products could create smoke-free cigarette alternatives and greatly
improve upon the success of inhalation smoking cessation
programs. The expected FDA action makes tobacco giant
Philip Morris International Inc. (PM), which
manufactures and sells cigarettes and other tobacco products
globally, a potential licensee for edible, absorbable nicotine
replacement therapeutics.
Another potential tobacco company beneficiary of Lexaria’s
technology is British American Tobacco PLC (BTI),
which has invested more than $1 billion in building its “Next
Generation Products” business, an assortment of alternative tobacco
and nicotine products aimed at reducing the risks associated with
smoking conventional cigarettes. Looking to the future, BTI was
among the first international tobacco companies to launch an
e-cigarette product in the UK. Touted as a tobacco alternative,
electronic cigarettes still rely on inhalation for nicotine
delivery, and the long-term health risk associated with
e-cigarettes remains in question. Bio-absorbable nicotine could
provide much safer and less expensive molecule delivery.
Lexaria’s potential in this market is best understood by
examining the application of the company’s technology to
cannabinoids, as well as its licensing strategy.
Medical cannabinoids have demonstrated therapeutic efficacy for
a variety of diseases and ailments; however, the human
gastrointestinal tract doesn’t absorb cannabinoids easily, causing
wide deviation in onset times and effectiveness. To achieve higher
effectiveness, consumers usually default to smoking. The key
differentiator between Lexaria’s technology and older tech on the
market is its ability to enhance the absorption of orally-ingested
cannabinoids while improving the “unusual” taste and allowing for
lower overall dosing with higher efficacy. Furthermore, Lexaria’s
lipophilic enhancement technology increases the bio-absorption of
cannabinoid edibles to between five and ten times that of
inhalation and reduces onset times by roughly 75% due to rapid
bio-absorption and potential liver bypass.
In what will only be strengthened by issuance of the aforenoted
patent, Lexaria uses a low-cost, high-margin license and royalty
model of revenue generation. Since its technology is complimentary
to all ingested forms of cannabinoids and potentially multiple
other ingestible products, the company is positioned to license its
intellectual property to biopharmaceutical companies as a partner
rather than a competitor. In short, the enhanced technology
provides an additional layer of effectiveness designed to harmonize
with the intellectual property of third parties, such as GW
Pharmaceuticals PLC (NASDAQ: GWPH), as they deliver
best-in-class products to their existing large consumer groups.
GW Pharmaceuticals is the world’s largest cannabinoid
pharmaceutical company. Recognized for its multiple sclerosis (MS)
cannabinoid product, Sativex, GW Pharmaceuticals is developing and
commercializing multiple therapeutics from its cannabinoid product
platform across a range of disease areas. The company's lead
cannabinoid product candidate, Epidiolex, a liquid formulation of
pure plant-derived cannabidiol (CBD), is in phase III clinical
trials for the treatment of severe treatment-resistant epilepsy
syndromes. Preliminary results from the trials have produced
encouraging results and, if approved, could bring in blockbuster
sales.
Beyond the cannabinoid sector, Lexaria sees considerable
potential in applying its delivery technology to many other
consumer products, including NSAIDs like Advil. More than 70
million prescriptions and more than 30 billion over-the counter
tablets of NSAIDs are sold annually in the United States alone.
While NSAIDs are effective in relieving pain, fever and
inflammation, they can cause unwanted and sometimes dangerous side
effects. Given a timely and predictable delivery system,
biopharmaceutical giant Pfizer (NYSE: PFE), the
maker of Advil, could easily find multiple applications for
Lexaria’s technology throughout its global portfolio of medicines,
vaccines and consumer health care products.
Lexaria is gaining considerable market traction with its
expanding patent portfolio, leveraging a unique technology that
positions the company as a potential partner to some of today’s
leading consumer brands. Building on this opportunity, Lexaria
continues to explore additional technologies that could deliver
value to its growing portfolio of patented technologies which now
has to be considered one of the broadest in the industry.
For more information on Lexaria Bioscience
Corp., please visit: Lexaria
Bioscience Corp. (CSE: LXX) (OTCQB: LXRP)
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