Mabcure, Inc. Featured in BioWorld® Today
August 25 2009 - 8:30AM
Business Wire
MabCure, Inc. (OTCBB:MBCI) (“MabCure”), a biotechnology company
using its proprietary technology to create highly specific
monoclonal antibodies (MAbs) for the early detection of cancer, has
been featured in the June 4, 2009 edition of BioWorld® Today,
biotech’s most respected news source for over seventeen years.
The cover story, written by Jennifer Boggs and titled “MabCure’s
Revamped Hybridoma Approach Seeks Cancer Antigens,” describes the
company’s “new take on a classic drug discovery technology,”
detailing how MabCure is developing monoclonal antibodies against
difficult-to-pinpoint tumor specific antigens (TSA) for the
diagnostics market. In the article Dr. Amnon Gonenne, the company’s
president and CEO, explained that while cancer is 90-95% curable if
caught early, the challenge in early detection lies in the lack of
clearly identified cancer markers.
Highlighted in the piece is MabCure’s proof of concept which
came in melanoma “…where scientists selected about half a dozen
antibodies from ‘tens of thousands’ that are highly specific to
melanoma –with no cross-reaction to predecessor melanoma cells –for
in vitro testing.” That large pool of antibodies necessary to draw
out those highly specific antibodies to melanoma was created using
MabCure’s proprietary re-engineered hybridoma technology, which can
produce 10,000-20,000 antibodies in just four-to-six weeks. By way
of comparison, classic hybridoma technology is relatively
inefficient, producing around 1,000 antibodies in four-to-six
months. Recombinant technology is favored to classic hybridoma for
its efficiency, but it generally requires the knowledge of the
antigens, which in the case of cancer, has been elusive. In
addition, it is unable to make antibodies to sugar-coated antigens
which is often the case for cell surface proteins (antigens), and
cancer cells in particular. MabCure’s unique approach offers the
best of both processes, one that is both efficient and highly
specific. Regarding the success of this proof of concept, Dr.
Gonenne said “. . . the theory was that the antibodies would
recognize any type of melanoma cell, and researchers proved it by
successfully testing them against ocular melanoma tissue.” The
anti-melanoma antibodies were able to recognize both advance and
early disease of the eye suggesting that the MabCure technology
could potentially generate antibodies that can recognize early
disease in other cancers as well.
The article went on to note that MabCure is gearing up for
clinical testing in prostate and ovarian cancers and that the
company intends to seek a commercial partner in the diagnostic
field for those programs.
“We are delighted to receive coverage of this caliber in a
publication as venerable as BioWorld Today,” says Dr. Gonenne.
“Media stories such as this afford us the opportunity to relay our
story to the scientific community, investors, and the
public-at-large.”
For more news and information on MabCure Inc., please visit
www.IRGnews.com/coi/MBCI where you can find a fact sheet on the
company, investor presentations, and more.
About MabCure Inc.
MabCure is a biotechnology company whose vision is to change the
perception of cancer as being a largely incurable disease. MabCure
owns proprietary technology for the creation of unique and highly
specific monoclonal antibodies (MAbs), which will be developed as
diagnostic tools, imaging agents, and drugs to treat lethal
cancers. MabCure initial goal is to develop its novel MAbs as
diagnostic tools for the detection of Ovarian and Prostate cancers
at an early stage, when these diseases are still localized and
highly curable. For further information visit the Company’s website
www.mabcure.com.
Forward-Looking Statement
This news release contains “forward-looking statements”.
Statements in this news release which are not purely historical are
forward-looking statements and include any statements regarding
beliefs, plans, expectations or intentions regarding the future.
Actual results could differ from those projected in any
forward-looking statements due to numerous factors. Such factors
include, among others, the change of business focus of the
management of the Company and the inability of the Company to
pursue its current objectives. These forward-looking statements are
made as of the date of this news release and the Company assume no
obligation to update the forward-looking statements, or to update
the reasons why actual results could differ from those projected in
the forward-looking statements.
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