InNexus Announces Achieving Business Milestone in Development of Intracellular SuperAntibody(TM) Therapeutics
March 14 2005 - 9:00AM
PR Newswire (US)
InNexus Announces Achieving Business Milestone in Development of
Intracellular SuperAntibody(TM) Therapeutics TSX.V: IXS OTC BB:
IXSBF VANCOUVER, March 14 /PRNewswire-FirstCall/ -- InNexus
Biotechnology Inc., an innovative antibody-driven drug development
company, announces the achievement of a business milestone in the
development of intracellular SuperAntibody(TM) therapeutics. With
the receipt of the first of three high affinity anti-apoptosis
monoclonal antibodies from its co-development partner, Epitomics,
Inc., InNexus has established an important foundation on which to
advance SuperAntibody(TM) platform based drugs from early-stage
testing to eventual commercialization. Commenting on the
announcement, Dr. A. Charles Morgan, President of InNexus, said:
"The antibody transfer marks an early and critical milestone in the
development of intracellular SuperAntibody(TM) therapeutics.
Utilizing our TransMAb(TM) technology platform, the newly enhanced
TransMab antibodies will be able to enter inside cells to either
turn on or turn off the apoptotic process, leading to the creation
of new, useful and never before seen medications in areas as stroke
and cancer." Garth Likes, Vice President of Business Development
added: "Using our TransMAb(TM) technology platform, we are able to
regulate cellular functions and believe it represents a new
paradigm in the use of antibodies and SuperAntibodies(TM) for the
development of novel therapeutics and diagnostics." Apoptosis is
the normal biochemical process in cells which triggers the eventual
death of a cell, a process required for the body to grow and become
fully formed. Defective apoptotic processes have been implicated in
a wide variety of diseases, sometimes causing premature cell-loss
disorders, such as in the case of stroke and heart attack.
Additionally, it is thought some forms of cancer may result when
apoptosis is somehow interrupted, allowing cells to grow unchecked,
resulting in a cancerous tumour. Under the terms of the
co-development agreement, Epitomics will supply humanized
antibodies for defined intracellular targets with InNexus enhancing
these antibodies with its TransMAb(TM) technology platform,
enabling intracellular delivery. The companies are jointly
developing therapeutic, diagnostic and life science products. About
Epitomics Epitomics, Inc. is a privately held biotechnology company
that develops and commercializes its proprietary rabbit monoclonal
antibody technology for use in the research community, diagnostic
and therapeutic markets through licensing, service and product
sales. Epitomics also has a novel humanization technology.
Epitomics has headquarters in Burlingame, California, and a wholly
owned subsidiary in Hangzhou, China and has worked with Sugen,
Genentech, Upstate USA, Exelixix and Ventanna to name a few. For
more information, please visit http://www.epitomics.com/ About
InNexus InNexus is an innovative antibody-driven drug development
company that has developed two technology platforms,
SuperAntibody(TM) and TransMAbs(TM), which improve the potency of
existing antibody products while opening new markets and disease
applications. Both platforms utilize unique, novel and patented
methods and technologies of InNexus. InNexus is headquartered in
British Columbia, Canada and has its own in-house developmental
facilities. These development facilities provide validation of
protein and peptide discoveries, enabling InNexus (and its
strategic partners) to advance novel drug therapeutics and
diagnostics. To learn more about InNexus please visit
http://www.innexusbiotech.com/ This news release contains
forward-looking statements within the meaning of the Private
Securities Litigation Reform Act of 1995. These statements are not
historical facts and are subject to risks and uncertainties which
could cause actual results and the timing of certain events to
differ materially from those set forth in or implied herein
including, without limitation, risks associated with clinical
development, regulatory approvals, product commercialization,
intellectual property claims litigation and other risks associated
with the Company's proposed activities. On behalf of the Board of
Directors of InNexus Biotechnology, Inc. "ALTON C. MORGAN" Dr. A.
Charles Morgan President Investor Relations: Toll-free:
1-866-990-8382 or 1-888-271-0788 The TSX Venture Exchange has
neither approved nor disapproved of the information contained
herein. DATASOURCE: InNexus Biotechnology, Inc. CONTACT: Investor
Relations: Toll-free: 1-866-990-8382 or 1-888-271-0788,
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