• Phase II Trial results expected by year end

MyMD Pharmaceuticals, Inc. (“MYMD”) is pleased to announce that its common shares will begin trading today, April 19th, on the NASDAQ Stock Market (“NASDAQ”) under the ticker symbol “MYMD.”

MyMD Pharmaceuticals intends to focus on developing and commercializing novel immunotherapy pipeline assets, including MYMD-1, a first-in-class drug being developed to treat autoimmune and age-related diseases, including extending the human lifespan. MyMD recently announced a Phase II trial that will initiate during the near term with results expected by year end.

"The listing of our shares on the Nasdaq marks a significant milestone for the company, in combination with our upcoming phase II trial and our clinical development pipeline, all of which should lead to increased visibility in the near term for our investors,” said Chris Chapman, M.D., President and Chief Medical Officer of MyMD.

About MyMD Pharmaceuticals, Inc.

MyMD is a clinical stage pharmaceutical company committed to extending healthy lifespan by focusing on developing two therapeutic platforms. MYMD-1 is a drug platform based on a clinical stage small molecule that regulates the immunometabolic system to control TNF-α and other pro-inflammatory cytokines. MYMD-1 is being developed to treat autoimmune diseases, including those currently treated with non-selective TNF-α blocking drugs, and aging and longevity. SUPERA-CBD is a drug platform based on a novel (patent pending) synthetic derivative of cannabidiol (CBD) that targets numerous key receptors including CB2 and opioid receptors and inhibits monoamine oxidase. SUPERA-CBD is being developed to address the rapidly growing CBD market, that includes FDA approved drugs and CBD products not currently regulated as a drug. For more information, visit www.mymd.com.

Cautionary Statement Regarding Forward-Looking Statements

This press release may contain forward-looking statements. These forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results, performance or achievements to be materially different from any expected future results, performance, or achievements. Forward-looking statements speak only as of the date they are made and none of MYMD nor its affiliates assume any duty to update forward-looking statements. Words such as "anticipate," "believe," "could," "estimate," "expect," "may," "plan," "will," "would" and other similar expressions are intended to identify these forward-looking statements. Important factors that could cause actual results to differ materially from those indicated by such forward-looking statements include, without limitation: the timing of, and MYMD’s ability to, obtain and maintain regulatory approvals for clinical trials of MYMD’s pharmaceutical candidates, the timing and results of MMMD’s planned clinical trials for its pharmaceutical candidates, the amount of funds MYMD requires for its pharmaceutical candidates; increased levels of competition; changes in political, economic or regulatory conditions generally and in the markets in which MYMD operates; MYMD’s ability to retain and attract senior management and other key employees; MYMD’s ability to quickly and effectively respond to new technological developments; MYMD’s ability to protect its trade secrets or other proprietary rights, operate without infringing upon the proprietary rights of others and prevent others from infringing on MYMD’s proprietary rights; and the impact of the ongoing COVID-19 pandemic on MYMD’s results of operations, business plan and the global economy. A discussion of these and other factors with respect to MYMD is set forth in the registration statement on Form S-4 filed by MYMD on January 15, 2021, as amended. Forward-looking statements speak only as of the date they are made and MYMD disclaims any intention or obligation to revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Investor Contact: Brett Mass 646-536-7331 brett@haydenir.com www.haydenir.com

Media Contact: Will Johnson 201-465-8019 MYMD@antennagroup.com www.antennagroup.com

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