------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 1 OF 9 PAGES
------------------- -----------------

 UNITED STATES
 SECURITIES AND EXCHANGE COMMISSION
 WASHINGTON, D.C. 20549


 SCHEDULE 13D
 UNDER THE SECURITIES EXCHANGE ACT OF 1934
 (AMENDMENT NO. 2 )*


 Memory Pharmaceuticals Corp.
--------------------------------------------------------------------------------
 (Name of Issuer)

 Common Stock, $0.001 par value
--------------------------------------------------------------------------------
 (Title of Class of Securities)

 58606R403
--------------------------------------------------------------------------------
 (CUSIP Number)

 Raymond Charest
 c/o Oxford Bioscience Partners IV L.P.
 222 Berkeley Street
 Boston, Massachusetts 02116
 (617-357-7474)
--------------------------------------------------------------------------------
 (Name, Address and Telephone Number of Person Authorized to Receive
 Notices and Communications)

 November 25, 2008
--------------------------------------------------------------------------------
 (Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition that is the subject of this Schedule 13D, and is filing this
schedule because of ss.ss.240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the
following box.

NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See ss.240.13d-7 for other
parties to whom copies are to be sent.

* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).


------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 2 OF 9 PAGES
------------------- -----------------


 Schedule 13D

Item 1. Security and Issuer.
 --------------------

 This statement relates to the Common Stock, $0.001 par value (the "Common
Stock") of Memory Pharmaceuticals Corp. (the "Issuer"), having its principal
executive office at 100 Philips Parkway, Montvale, New Jersey 07645.

Item 2. Identity and Background.
 ------------------------

 (a) This statement is being filed by Oxford Bioscience Partners IV L.P.
("Oxford IV"); mRNA Fund II L.P. ("mRNA II" and, together with Oxford IV, the
"Funds"); OBP Management IV L.P. ("OBP IV"), which is the sole general partner
of the Funds; and Jeffrey T. Barnes ("Barnes"), Jonathan J. Fleming ("Fleming"),
Michael E. Lytton ("Lytton") and Alan G. Walton ("Walton") (collectively, the
"General Partners"). The General Partners are the individual general partners of
OBP IV. The Funds, OBP IV and the General Partners are sometimes referred to
collectively herein as the "Reporting Persons."

 (b) The address of the principal business office of the Funds, OBP IV,
Barnes, Fleming and Lytton is 222 Berkeley Street, Suite 1650, Boston,
Massachusetts 02116. The address of the principal business office of Walton is
315 Post Rd. West, Westport, Connecticut 06880.

 (c) The principal business of the Funds is to invest in and assist
growth-oriented businesses located principally in the United States. The
principal business of OBP IV is to manage the affairs of the Funds. The
principal business of each of the General Partners is to manage the affairs of
OBP IV.

 (d) During the five years prior to the date hereof, none of the Reporting
Persons has been convicted in a criminal proceeding.

 (e) During the five years prior to the date hereof, none of the Reporting
Persons has been a party to a civil proceeding of a judicial or administrative
body of competent jurisdiction ending in a judgment, decree or final order
enjoining future violations of, or prohibiting or mandating activities subject
to, Federal or State securities laws or finding any violation with respect to
such laws.

 (f) The Funds and OBP IV are limited partnerships organized under the laws
of the State of Delaware. Each of the General Partners is a United States
citizen.

Item 3. Source and Amount of Funds or Other Consideration.
 --------------------------------------------------

 Not applicable.

Item 4. Purpose of Transaction.
 -----------------------

 On November 25, 2008 the Issuer, Hoffman-La Roche Inc., a New Jersey
corporation ("Roche") and 900 North Point Acquisition Corporation, a Delaware
corporation and a wholly-owned subsidiary of Roche ("Merger Subsidiary") entered
into an Agreement and Plan of Merger (the "Merger Agreement," a copy of which is
attached hereto as Exhibit 1). Pursuant to the Merger Agreement, and subject to
its terms and conditions, Merger Subsidiary will commence a tender offer (the
"Offer") to acquire all of the outstanding shares of the Common Stock of the
Issuer. Further, pursuant to the Merger Agreement, after the consummation of the
Offer, and subject to the satisfaction or waiver of certain conditions set forth
in the Merger Agreement, Merger Subsidiary will merge with and into the Issuer
and Issuer will become a wholly-owned subsidiary of Roche.


------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 3 OF 9 PAGES
------------------- -----------------

 In connection with the Merger Agreement, the Funds, certain other
shareholders of the Issuer (the "Other Shareholders") and Roche entered into a
Stockholder Tender and Support Agreement (the "Tender Agreement," a copy of
which is attached hereto as Exhibit 2). Under the terms of the Tender Agreement,
the Funds have agreed, among other things, subject to the termination of the
Tender Agreement (1) to tender in the Offer (and not to withdraw) all shares of
the Issuer's Common Stock beneficially owned or thereafter acquired by them, (2)
to vote such shares in support of the merger in the event stockholder approval
is required to consummate the merger and against any competing transaction, (3)
to irrevocably appoint Roche as their proxy to vote such shares in connection
with the Merger Agreement, (4) to not, and to use best efforts to ensure its
affiliates do not: solicit, facilitate or encourage a third-party proposal of
acquisition or otherwise enter into any agreement related thereto, and (5) not
to otherwise transfer any of their shares. The Tender Agreement will terminate
upon the termination of the Merger Agreement or in certain other events.

 Except as set forth above, none of the Reporting Persons has any present
plans which relate to or would result in:

 (a) The acquisition by any person of additional securities of the Issuer,
or the disposition of securities of the Issuer;

 (b) An extraordinary corporate transaction, such as a merger,
reorganization or liquidation, involving the Issuer or any of its subsidiaries;

 (c) A sale or transfer of a material amount of assets of the Issuer or any
of its subsidiaries;

 (d) Any change in the present board of directors or management of the
Issuer, including any plans or proposals to change the number or term of
directors or to fill any existing vacancies on the board;

 (e) Any material change in the present capitalization or dividend policy of
the Issuer;

 (f) Any other material change in the Issuer's business or corporate
structure including but not limited to, if the issuer is a registered closed-end
investment company, any plans or proposals to make any changes in its investment
policy for which a vote is required by section 13 of the Investment Company Act
of 1940;

 (g) Changes in the Issuer's charter, bylaws or instruments corresponding
thereto or other actions which may impede the acquisition of control of the
Issuer by any person;

 (h) Causing a class of securities of the Issuer to be delisted from a
national securities exchange or to cease to be authorized to be quoted in an
inter-dealer quotation system of a registered national securities association;

 (i) A class of equity securities of the Issuer becoming eligible for
termination of registration pursuant to Section 12(g)(4) of the Securities
Exchange Act of 1934; or

 (j) Any action similar to any of those enumerated above.

Item 5. Interest in Securities of the Issuer.
 -------------------------------------

 (a) Oxford IV is the record owner of 3,595,503 shares of Common Stock and
warrants to purchase 911,902 shares of Common Stock exercisable within 60 days
(the "Oxford IV Warrants"), and thus may be deemed to be the beneficial owner of
4,507,405 shares of Common Stock (the "Oxford IV Shares"). mRNA II is the record
owner of 36,076 shares of Common Stock and warrants to purchase 9,149 shares of
Common Stock exercisable within 60 days (the "mRNA II Warrants"), and thus may
be deemed to be the beneficial owner of 45,225 shares of Common Stock (the "mRNA
II Shares"). As the sole general partner of each of Oxford IV


------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 4 OF 9 PAGES
------------------- -----------------

and mRNA II, OBP IV may be deemed to own beneficially the Oxford IV Shares and
the mRNA II Share. By virtue of their relationship as affiliated partnerships
that share a sole general partner, each of the Funds may be deemed to share the
power to direct the disposition and vote of the Oxford IV Shares and the mRNA II
Shares for an aggregate of 4,552,630 shares (the "Firm Shares"). As individual
general partners of OBP IV, each of the General Partners may be deemed to own
beneficially all of the Firm Shares.

 As general partners of the general partner of each of (i) Oxford Bioscience
Partners II L.P., a Delaware limited partnership; (ii) Oxford Bioscience
Partners (Adjunct) II L.P., a Delaware limited partnership; (iii) Oxford
Bioscience Partners (GS-Adjunct) II L.P., a Delaware limited partnership; (iv)
Oxford Bioscience Partners II (Annex) L.P., a Delaware limited partnership; and
(v) Oxford Bioscience Partners (Bermuda) II Limited Partnership, a Bermuda
limited partnership (collectively, the "OBP II Funds"), each of Fleming and
Walton may be deemed to own beneficially the 2,361,861 shares of Common Stock
and warrants to purchase 184,210 shares of Common Stock exercisable within 60
days (the "OBP II Warrants") held of record by the OBP II Funds (collectively,
the "OBP II Shares").

 Fleming holds options to purchase 50,000 shares of Common Stock exercisable
within 60 days (the "Fleming Options").

 Based on the Firm Shares, each Reporting Person, other than Fleming and
Walton, may be deemed to beneficially own 5.5% of the Common Stock of the
Issuer, which percentage is calculated based upon 83,164,101 shares, which
includes 82,243,050 shares reported to be outstanding in the Issuer's most
recent Form 10-Q, which was filed with respect to the period ending September
30, 2008 (the "10-Q Shares"), the Oxford IV Warrants and the mRNA II Warrants.
Based on the Firm Shares, the OBP II Shares and the Fleming Options, Fleming may
be deemed to beneficially own 8.6% of the Common Stock of the Issuer, which
percentage is calculated based upon 83,398,311 shares, which includes the 10-Q
Shares, the Oxford IV Warrants, the mRNA II Warrants, the OBP II Warrants and
the Fleming Options. Based on the Firm Shares and the OBP II Shares, Walton may
be deemed to beneficially own 8.5% of the Common Stock of the Issuer, which
percentage is calculated based upon 83,348,311 shares, which includes the 10-Q
Shares, the Oxford IV Warrants, the OBP II Warrants and the mRNA II Warrants.

 As described in Item 4, each of Oxford IV, mRNA II and the Other
Shareholders has agreed, pursuant to the terms of the Tender Agreement, among
other things, to vote to approve the merger contemplated in the Merger Agreement
and has granted Roche a proxy to vote their shares to approve the merger.

 The Funds and the Other Shareholders own, in the aggregate, 24,221,466
shares of Common Stock and options and warrants to purchase 6,523,533 shares of
Common Stock.

 If the Funds and the Other Shareholders are considered a "group" because of
their participation in the Tender Agreement, each Reporting Person may be deemed
to beneficially own 30,744,999 shares of Common Stock of the Issuer,
representing 34.6% of the Common Stock of the Issuer, which percentage is
calculated based upon the 10-Q Shares and the aggregate options and warrants to
purchase shares of Common Stock held by the Funds and the Other Shareholders
(assuming for purposes herein that all such options and warrants are exercisable
within 60 days). Each Reporting Person disclaims membership in a "group." Each
Reporting Person also disclaims beneficial ownership of any shares of the
Issuer, except for (i) Oxford IV, with respect to the Oxford IV Shares, (ii)
mRNA II, with respect to the mRNA II Shares and (iii) Fleming, with respect to
the Fleming Options.

 (b) Regarding the number of shares as to which such person has:

 (i) sole power to vote or to direct the vote:

 0 shares for each of the Reporting Persons, other
 than Fleming, and 50,000 shares for Fleming.

 (ii) shared power to vote or to direct the vote:


------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 5 OF 9 PAGES
------------------- -----------------

 4,552,630 shares for each of the Reporting Persons,
 other than Fleming and Walton, and 7,098,701 shares
 for Fleming and Walton.

 (iii) sole power to dispose or to direct the disposition:

 0 shares for each of the Reporting Persons, other
 than Fleming, and 50,000 shares for Fleming.

 (iv) shared power to dispose or to direct the disposition:

 4,552,630 shares for each of the Reporting Persons,
 other than Fleming and Walton, and 7,098,701 shares
 for Fleming and Walton.

 (c) Except as set forth in Item 3 above, none of the Reporting Persons has
effected any transaction in the Common Stock during the last 60 days.

 (d) No other person is known to have the right to receive or the power to
direct the receipt of dividends from, or any proceeds from the sale of, Shares
beneficially owned by any of the Reporting Persons.

 (e) Mark P. Carthy previously ceased to be a general partner of OBP IV and
accordingly is no longer deemed to share the power to direct the disposition or
vote of the Firm Shares.

Item 6. Contracts, Arrangements, Understandings or Relationships With Respect to
 ------------------------------------------------------------------------
 Securities of the Issuer.
 -------------------------

 See Items 4 and 5 above.

Item 7. Material to be Filed as Exhibits.
 ---------------------------------

 Exhibit 1 - Agreement and Plan of Merger, dated as of November 25, 2008*

 Exhibit 2 - Stockholder Tender and Support Agreement, dated as of November
 25, 2008*

 Exhibit 3 - Agreement regarding filing of joint Schedule 13D.

 Exhibit 4 - Power of Attorney regarding Schedule 13D filings.





--------
* Incorporated by reference to the Issuer's Current Report on Form 8-K filed
with the Securities and Exchange Commission on November 25, 2008.


------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 6 OF 9 PAGES
------------------- -----------------

 SIGNATURES

 After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

Dated: December 5, 2008

 OXFORD BIOSCIENCE PARTNERS IV L.P.

 By: OBP MANAGEMENT IV L.P.
 Its General Partner

 By: *
 ----------------------------
 Jonathan J. Fleming
 General Partner

 mRNA FUND II L.P.

 By: OBP MANAGEMENT IV L.P.
 Its General Partner

 By: *
 ----------------------------
 Jonathan J. Fleming
 General Partner

 OBP MANAGEMENT IV L.P.

 By: *
 -----------------------------
 Jonathan J. Fleming
 General Partner


 *
 ----------------------------
 Jeffrey T. Barnes


 *
 ----------------------------
 Jonathan J. Fleming


 *
 ----------------------------
 Michael E. Lytton


 *
 ----------------------------
 Alan G. Walton



*By: /s/ Raymond Charest
 --------------------------------------
 Raymond Charest as Attorney-in-Fact

 This Schedule 13D was executed by Raymond Charest pursuant to a Power of
Attorney, filed with the Securities and Exchange Commission on April 8, 2004,
which Power of Attorney is incorporated herein by reference and a copy of which
are attached hereto as Exhibit 4.


------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 7 OF 9 PAGES
------------------- -----------------


 Exhibit 3
 ---------
 JOINT FILING UNDERTAKING

 Pursuant to Rule 13d-1(k)(1) promulgated under the Securities Exchange Act
of 1934, as amended, each of the undersigned agree that the Schedule 13D, and
any amendments thereto, filed with respect to the beneficial ownership by the
undersigned of the equity securities of Memory Pharmaceuticals Corp., is being
filed on behalf of each of the undersigned.

Dated: December 5, 2008

 OXFORD BIOSCIENCE PARTNERS IV L.P.

 By: OBP MANAGEMENT IV L.P.
 Its General Partner

 By: *
 -------------------------------
 Jonathan J. Fleming
 General Partner

 mRNA FUND II L.P.

 By: OBP MANAGEMENT IV L.P.
 Its General Partner

 By: *
 -------------------------------
 Jonathan J. Fleming
 General Partner

 OBP MANAGEMENT IV L.P.

 By: *
 ------------------------------
 Jonathan J. Fleming
 General Partner

 *
 -----------------------------
 Jeffrey T. Barnes

 *
 -----------------------------
 Jonathan J. Fleming

 *
 -----------------------------
 Michael E. Lytton

 *
 -----------------------------
 Alan G. Walton


*By: /s/ Raymond Charest
 ---------------------------------------
 Raymond Charest as Attorney-in-Fact

 This Agreement to file Amendment No. 2 to Schedule 13D was executed by
Raymond Charest pursuant to a Power of Attorney, filed with the Securities and
Exchange Commission on April 8, 2004, which Power of Attorney is incorporated
herein by reference and a copy of which are attached hereto as Exhibit 4.


------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 8 OF 9 PAGES
------------------- -----------------


 Exhibit 4
 ---------
 POWER OF ATTORNEY

 KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears
below hereby constitutes and appoints Raymond Charest, Alexia Pearsall and
Jonathan J. Fleming, and each of them, with full power to act without the other,
his true and lawful attorney-in-fact and agent, with full power of substitution,
for him and in his name, place and stead, in any and all capacities (until
revoked in writing) to sign any and all instruments, certificates and documents
required to be executed on behalf of himself as an individual or in his capacity
as a general partner or authorized signatory, as the case may be, on behalf of
any of Oxford Bioscience Partners IV L.P., mRNA II L.P., or OBP Management IV
L.P., pursuant to section 13 or 16 of the Securities Exchange Act of 1934, as
amended (the "Exchange Act"), and any and all regulations promulgated thereunder
and to file the same, with all exhibits thereto, and any other documents in
connection therewith, with the Securities and Exchange Commission, and with any
other entity when and if such is mandated by the Exchange Act or by the By-laws
of the National Association of Securities Dealers, Inc., granting unto said
attorney-in-fact and agent full power and authority to do and perform each and
every act and thing requisite and necessary fully to all intents and purposes as
he might or could do in person thereby ratifying and confirming all that said
attorney-in-fact and agent, or his substitute or substitutes, may lawfully do or
cause to be done by virtue hereof, or may have done in connection with the
matters described above. IN WITNESS WHEREOF, this Power of Attorney has been
signed as of the 8th day of April, 2004.


 OXFORD BIOSCIENCE PARTNERS IV L.P.
 by its General Partner, OBP MANAGEMENT IV L.P.


 By: /s/ Jonathan J. Fleming
 -----------------------------------
 Name: Jonathan J. Fleming
 Title: General Partner


 mRNA FUND II L.P.
 By its General Partner, OBP MANAGEMENT IV L.P.


 By: /s/ Jonathan J. Fleming
 -----------------------------------
 Name: Jonathan J. Fleming
 Title: General Partner


------------------- -----------------
CUSIP NO. 58606R403 13D PAGE 9 OF 9 PAGES
------------------- -----------------


 OBP MANAGEMENT IV L.P.


 By: /s/ Jonathan J. Fleming
 -----------------------------------
 Name: Jonathan J. Fleming
 Title: General Partner


 /s/ Jeffrey T. Barnes
 --------------------------------
 Jeffrey T. Barnes


 /s/ Mark P. Carthy
 --------------------------------
 Mark P. Carthy


 /s/ Jonathan J. Fleming
 --------------------------------
 Jonathan J. Fleming


 /s/ Michael E. Lytton
 --------------------------------
 Michael E. Lytton


 /s/ Alan G. Walton
 --------------------------------
 Alan G. Walton

Memory Pharmaceuticals Corp (MM) (NASDAQ:MEMY)
Historical Stock Chart
From Jun 2024 to Jul 2024 Click Here for more Memory Pharmaceuticals Corp (MM) Charts.
Memory Pharmaceuticals Corp (MM) (NASDAQ:MEMY)
Historical Stock Chart
From Jul 2023 to Jul 2024 Click Here for more Memory Pharmaceuticals Corp (MM) Charts.