HOUSTON, Jan. 15, 2019 /PRNewswire/ -- Marker
Therapeutics, Inc. (Nasdaq:MRKR), a clinical-stage
immuno-oncology company specializing in the development of
next-generation T cell-based immunotherapies for the treatment of
hematological malignancies and solid tumor indications, today
reported that data from four abstracts—including three oral
presentations—were accepted for presentation at the Transplantation
& Cellular Therapy (TCT) Meetings of the American Society for
Blood and Marrow Transplantation and the Center for International
Blood and Marrow Transplant Research (ASBMT and
CIBMTR). The studies summarize data achieved using multi-tumor
antigen specific T cells that were developed at Baylor College of Medicine in the laboratories of
Dr. Swati Naik, Dr. Ann Leen, and Dr. Premal
Lulla, and exclusively licensed to Marker.
The TCT meetings of ASBMT and CIBMTR 2019 will take place in
Houston, TX from February 20-24.
Oral Presentation Details
Presentation Title: "Targeting Lymphomas Using
Non-Engineered, Multi-Antigen-Specific T Cells" (Abstract #24)
Session Title: Session C - Lymphoma and Myeloma
Session Date/Time: Wednesday, February 20, 2019,
5:00 p.m. CST
Presentation Title: "Administering Leukemia-Directed
Donor Lymphocytes to Patients with AML or MDS to Prevent or Treat
Post-Allogeneic HSCT Relapse" (Abstract #11)
Session Title: Session A - Acute and Chronic
Leukemia
Session Date/Time: Wednesday, February 20, 2019,
5:45 p.m. CST
Presentation Title: "Adoptive T-Cell Therapy for
Acute Lymphoblastic Leukemia Targeting Multiple Tumor-Associated
Antigens" (Abstract #78)
Session Title: Session K - Immune and Gene Therapy
Session Date/Time: Saturday, February 23, 2019,
5:00 p.m. CST
Poster Presentation Details
Presentation Title: "Safety and Efficacy of
Multiantigen-Targeted T Cells for Multiple Myeloma" (Abstract
#621)
Presentation Date/Time: Saturday, February 23,
6:45 p.m. CST
About Marker Therapeutics, Inc.
Marker Therapeutics,
Inc. is a clinical-stage immuno-oncology company specializing in
the development of next-generation T cell-based immunotherapies for
the treatment of hematological malignancies and solid tumor
indications. Marker's cell therapy technology is based on the
selective expansion of non-engineered, tumor-specific T cells that
recognize tumor associated antigens (i.e. tumor targets) and kill
tumor cells expressing those targets. Once infused into patients,
this population of T cells attacks multiple tumor targets and acts
to activate the patient's immune system to produce broad spectrum
anti-tumor activity. Because Marker does not genetically engineer
its T cells, when compared to current engineered CAR-T and
TCR-based approaches, its products (i) are significantly less
expensive and easier to manufacture, (ii) appear to be markedly
less toxic, and (iii) are associated with meaningful clinical
benefit. As a result, Marker believes its portfolio of T cell
therapies has a compelling therapeutic product profile, as compared
to current gene-modified CAR-T and TCR-based therapies.
Marker is also advancing a number of innovative peptide- and
gene-based immuno-therapeutics for the treatment of metastatic
solid tumors, including the Folate Receptor Alpha program (TPIV200)
for breast and ovarian cancers and the HER2/neu program
(TPIV100/110) for breast cancer, currently in Phase II clinical
trials. In parallel, we are developing a proprietary DNA expression
technology named PolyStart™ that can enhance the ability of the
immune system to recognize and destroy diseased cells.
For additional information, please call toll free at (904)
862-6490 or visit: markertherapeutics.com
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Forward-Looking Statement Disclaimer
This release
contains forward-looking statements for purposes of the safe harbor
provisions of the Private Securities Litigation Reform Act of 1995.
Statements in this news release concerning the Company's
expectations, plans, business outlook or future performance, and
any other statements concerning assumptions made or expectations as
to any future events, conditions, performance or other matters, are
"forward-looking statements". Forward-looking statements include
statements regarding our intentions, beliefs, projections, outlook,
analyses or current expectations concerning, among other things:
our research and development activities relating to our multi-tumor
antigen specific T cell therapies; our TPIV200 and TPIV100/110
programs and our PolyStart™ program; the effectiveness of these
programs or the possible range of application and potential
curative effects and safety in the treatment of diseases; and, the
timing and success of our clinical trials, as well as multi-tumor
antigen specific T cell clinical trials conducted by Baylor College of Medicine. Forward-looking
statements are by their nature subject to risks, uncertainties and
other factors which could cause actual results to differ materially
from those stated in such statements. Such risks, uncertainties and
factors include, but are not limited to the risks set forth in the
Company's most recent Form 10-K, 10-Q and other SEC filings which
are available through EDGAR at www.sec.gov. The Company assumes no
obligation to update our forward-looking statements whether as a
result of new information, future events or otherwise, after the
date of this press release.
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SOURCE Marker Therapeutics, Inc.