BFRM Bioform Medical (MM)

SAN MATEO, Calif., Dec. 12 /PRNewswire-FirstCall/ -- BioForm Medical, Inc. (NASDAQ:BFRM) today announced the publication of a multi-center, randomized, blinded comparative study of nasolabial fold treatments reporting higher patient satisfaction with its Radiesse(R) dermal filler than reported after treatment with either Juvederm(TM) or Perlane(R). The results of this study were published in the December 2007 Filler Issue of the Journal of Dermatologic Surgery, a peer-reviewed publication of the American Society of Dermatologic Surgery. In this first direct comparison study of Radiesse dermal filler against two leading competitors, the study concluded that 1) patients were substantially more satisfied if they received Radiesse dermal filler than other leading fillers tested, 2) patients who received Radiesse were substantially more likely to return for future treatments, and 3) Radiesse dermal filler offers advantages in durability and cost, while exhibiting similar safety characteristics as hyaluronic acid fillers. Results from two other studies were also published in this special issue of Dermatologic Surgery. The results of the pivotal U.S. clinical study of Radiesse dermal filler versus CosmoPlast(R) (collagen), demonstrated superiority of Radiesse to CosmoPlast on virtually every effectiveness measure in the study, and Radiesse dermal filler was found to provide a comparable safety profile to collagen. Three leading dermatologists, Dr. Neil Sadick, Dr. Bruce Katz, and Dr. Deborshi Roy, also published in this special issue their long-term clinical experience with Radiesse, also demonstrating safety of Radiesse in clinical use and high patient satisfaction. "We often hear from our customers that the reason they choose Radiesse for many of their patients is first and foremost that they believe their patients are more satisfied with Radiesse than other dermal filler options. The published report of the comparative study of Radiesse against leading hyaluronic acid fillers demonstrates this difference in a well-controlled clinical study setting," commented Steven Basta, Chief Executive Officer of BioForm Medical. "We are grateful to the many investigators in the U.S. and European clinical studies, and to the leading physicians who routinely take time out of their practice to report on their growing positive experiences with Radiesse." Radiesse vs. Juvederm and Perlane Clinical Trial A 205-patient comparative study was conducted at five clinical sites in Europe to assess patient satisfaction and aesthetic improvement in treating nasolabial folds with Radiesse dermal filler as compared to three leading hyaluronic acid fillers, Perlane and two forms of Juvederm. The results of this prospective, multi-center, randomized study, led by Marion Moers-Carpi, MD, Hautok, Munich, Germany, demonstrated higher patient satisfaction, higher likelihood to return for additional treatment, and a greater likelihood to recommend treatment with Radiesse dermal filler, as compared to the three hyaluronic acid products tested: Juvederm 24 (not available in the U.S.), Juvederm 24HV (known as Juvederm Ultra in the U.S.) and Perlane. The study was designed to measure the results achieved by several products on a comparative basis after the completion of two treatments, at baseline and at four months in order to achieve optimal correction. The paper published in the Journal of Dermatologic Surgery reports on results achieved through a 12-month follow-up after the second treatment. The results from the study demonstrated that at 12 months after the last injection, 90% of Radiesse treated patients rated their satisfaction as "satisfied" or "extremely satisfied" compared to 48% with Perlane (p