Duke University and Affymetrix Initiate Five-Year Translational Research Collaboration
January 09 2006 - 8:00AM
Business Wire
Affymetrix Inc. (Nasdaq:AFFX) announced today that it has entered
into a five-year collaboration with Duke University to analyze
genomic information across large patient samples. Under terms of
the agreement, Duke researchers will use Affymetrix GeneChip(R)
microarray technology to develop new applications for translational
research projects. The initial projects will focus on cancer and
cardiovascular disease. Duke researchers will use Affymetrix'
GeneChip HT (High-Throughput) System and arrays to perform
large-scale clinical studies. The Affymetrix technology will enable
them to more rapidly discover RNA and DNA patterns that can better
classify, manage and treat complex diseases. As part of the
agreement, Affymetrix will fund creative research and clinical
projects that could lead to new genomic applications on the
GeneChip platform, as well as novel diagnostics and screening
tests. "This is an exciting time when genomics offers the promise
of a deeper understanding of biology while at the same time
improving the practice of medicine," said Joseph Nevins, Ph.D.,
director of the IGSP Center for Applied Genomics & Technology
at Duke University. "By combining our research expertise with
Affymetrix' high-throughput microarray technology, we have the
opportunity to build on our prior work and develop gene expression
profiles that characterize oncogenic pathways and define tumor
phenotypes, which are important in determining clinical outcomes.
At the same time, this can translate into improved clinical care
and provide an important resource to enhance the use of microarray
technology for all Duke investigators." "Affymetrix is excited to
be working with a leading research organization such as Duke
University to help bring more effective personalized tests and
therapies to market faster," said Gregg Fergus, senior vice
president, Global Sales Operations at Affymetrix. "Together, we
hope to accelerate clinical research, improve patient care and open
the door to new genomic applications." Affymetrix collaborates with
academic institutions and patient advocacy groups through the
company's translational medicine program to develop more effective
treatments. Affymetrix GeneChip microarray technology helps
researchers tailor treatments for individual patients by
identifying and measuring the genetic information associated with
complex diseases. The translational medicine program complements
the Powered by Affymetrix(TM) program, which enables companies to
license GeneChip technology to develop innovative microarray
products. This custom-designed technology is being used in many
applications, including diagnostics, forensics, animal, industrial
and food testing. About Affymetrix Affymetrix scientists invented
the world's first high-density microarray in 1989 and began selling
the first commercial microarray in 1994. Since then, Affymetrix
GeneChip(R) technology has become the industry standard in
molecular biology research. Affymetrix technology is used by the
world's top pharmaceutical, diagnostic and biotechnology companies
as well as leading academic, government and not-for-profit research
institutes. More than 1,300 systems have been installed around the
world and nearly 3,000 peer-reviewed papers have been published
using the technology. Affymetrix' patented photolithographic
manufacturing process provides the most information capacity
available today on an array, enabling researchers to use a
whole-genome approach to analyzing the relationship between
genetics and health. Affymetrix is headquartered in Santa Clara,
Calif., with manufacturing facilities in Sacramento, Calif., and
Bedford, Mass. The company maintains important sales and marketing
operations in Europe and Asia and has about 1,000 employees
worldwide. For more information about Affymetrix, please visit the
company's Web site at www.affymetrix.com. All statements in this
press release that are not historical are "forward-looking
statements" within the meaning of Section 21E of the Securities
Exchange Act as amended, including statements regarding Affymetrix'
"expectations," "beliefs," "hopes," "intentions," "strategies," or
the like. Such statements are subject to risks and uncertainties
that could cause actual results to differ materially for Affymetrix
from those projected, including, but not limited to: risks of the
Company's ability to achieve and sustain higher levels of revenue,
higher gross margins, reduced operating expenses; uncertainties
relating to technological approaches, manufacturing (including
risks related to the Company's ability to achieve hoped-for
manufacturing yields for certain array products, including the
ability to identify and resolve manufacturing problems), product
development (including uncertainties relating to commercial and
technological success of the strategic alliance between Duke
University and Affymetrix discussed in this press release);
personnel retention; uncertainties related to cost and pricing of
Affymetrix products; dependence on collaborative partners;
uncertainties relating to sole source suppliers; uncertainties
relating to FDA and other regulatory approvals; competition; risks
relating to intellectual property of others and the uncertainties
of patent protection and litigation. These and other risk factors
are discussed in Affymetrix' Form 10-K for the year ended December
31, 2004, and other SEC reports, including its Quarterly Reports on
Form 10-Q for subsequent quarterly periods. Affymetrix expressly
disclaims any obligation or undertaking to release publicly any
updates or revisions to any forward-looking statements contained
herein to reflect any change in Affymetrix' expectations with
regard thereto or any change in events, conditions or circumstances
on which any such statements are based. NOTE: Affymetrix, the
Affymetrix logo and GeneChip are registered trademarks owned or
used by Affymetrix Inc.
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