As
filed with the Securities and Exchange Commission on October 24, 2023
Registration
Statement No. 333-
UNITED
STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM
S-8
REGISTRATION
STATEMENT
UNDER
THE SECURITIES ACT OF 1933
TITAN
PHARMACEUTICALS, INC.
(Exact Name of Registrant
as Specified in Its Charter)
Delaware |
|
94-3171940 |
(State
or Other Jurisdiction of Incorporation or Organization) |
|
(I.R.S.
Employer
Identification Number) |
400
Oyster Point Blvd., Suite 505
South
San Francisco, California 94080
Tel:
(650) 244-4990
(Address,
Including Zip Code, and Telephone Number, Including Area Code, of Registrant’s Principal Executive Offices)
TITAN
PHARMACEUTICALS, INC. 2015 OMNIBUS EQUITY INCENTIVE PLAN
(Full
Title of Plan)
Kate
Beebe DeVarney, Ph.D., President and Chief Operating Officer
Titan
Pharmaceuticals, Inc.
400
Oyster Point Blvd., Suite 505
South
San Francisco, California 94080
Tel:
(650) 244-4990
(Name,
address, including zip code, and telephone number, including area code, of agent for service)
With
a copy to:
Kenneth A. Schlesinger, Esq.
Spencer Feldman, Esq.
Olshan Frome Wolosky LLP
1325 Avenue of the Americas
New York, New York 10019
(212) 451-2300
Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting
company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,”
“smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
|
Large accelerated filer |
☐ |
Accelerated filer |
☐ |
|
Non-accelerated filer |
☒ |
Smaller reporting company |
☒ |
|
Emerging growth company |
☐ |
|
If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for
complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities
Act. ☐
EXPLANATORY
NOTE
Titan
Pharmaceuticals, Inc. (the “Company” or the “Registrant”) is filing this registration statement
on Form S-8 (this “Registration Statement”) to register an additional 2,492,424 shares (the “Additional
Shares”) of its common stock, par value $0.001 per share (“Common Stock”), issuable pursuant to the
terms and in the manner set forth in the Company’s Amended and Restated 2015 Omnibus Equity Incentive Plan, (the “2015
Plan”).
The
stockholders of the Company originally approved the 2015 Plan on August 24, 2015 with 7,500,000 shares of Common Stock authorized
for issuance under the 2015 Plan. On September 29, 2015, the Company effected a 1-for-5.5 reverse stock split, following which
the number of shares of Common Stock authorized for issuance under the 2015 Plan was reduced from 7,500,000 to 1,363,637. In November 2015,
the Company filed a registration statement on Form S-8 (the “2015 Form S-8”) to register the 1,363,637 shares
authorized under the 2015 Plan.
On
August 2, 2016, the stockholders of the Company approved an amendment to the 2015 Plan to increase the number of shares of
Common Stock authorized for issuance under the 2015 Plan from 1,363,637 to 2,500,000. On August 7, 2018, the stockholders
of the Company approved an amendment to the 2015 Plan to increase the number of shares of Common Stock authorized for issuance
under the 2015 Plan from 2,500,000 to 3,500,000. On January 23, 2019, the stockholders of the Company approved an amendment
to the 2015 Plan to increase the number of shares of Common Stock authorized for issuance under the 2015 Plan from 3,500,000 to
10,000,000. Also on January 23, 2019, the Company effected a 1-for-6 reverse stock split, following which the number of shares
of Common Stock authorized for issuance under the 2015 Plan was reduced to from 10,000,000 to 1,666,667.
On
November 30, 2020, the Company effected a 1-for-30 reverse stock split, following which the number of shares of Common Stock
authorized for issuance under the 2015 Plan was reduced from 1,666,667 to 55,556. On January 8, 2021, the stockholders of
the Company approved an amendment to the 2015 Plan to, among other things, increase the number of shares of Common Stock authorized
for issuance under the 2015 Plan from 55,556 to 1,000,000.
As
a result of the aforementioned amendments to the 2015 Plan and reverse stock splits, as of June 28 2023, there were a total of
1,000,000 shares of Common Stock authorized under the 2015 Plan, of which only 7,576 shares were registered under the 2015 Form S-8,
and 992,424 shares were not. On June 29, 2023, the stockholders of the Company approved an amendment to the 2015 Plan to
increase the number of shares of Common Stock authorized for issuance under the 2015 Plan from 1,000,000 to 2,500,000. As a result,
this Registration Statement is registering an additional 2,492,424 shares of Common Stock issuable pursuant to the 2015 Plan. The
2,492,424 shares of Common Stock being registered on this Registration Statement includes 1,464,541 shares held by certain
securityholders identified in the section of the Reoffer Prospectus (as defined below) entitled “Selling
Securityholders.” Such shares have been previously issued pursuant to the Company’s Amended and Restated 2015 Omnibus
Equity Incentive Plan or may be acquired in connection with stock options granted to the Selling Securityholders.
This
Registration Statement also includes a prospectus (the “Reoffer Prospectus”) prepared in accordance with General
Instruction C of Form S-8 and in accordance with the requirements of Part I of Form S-3. This Reoffer Prospectus may be used for
the reoffer and resale of shares of Common Stock on a continuous or delayed basis that may be deemed to be “restricted securities”
and/or “control securities” within the meaning of the Securities Act of 1933, as amended (the “Securities
Act”), and the rules and regulations promulgated thereunder, that have previously been issued to certain of our executive
officers, employees, consultants and directors identified in the Reoffer Prospectus. The number of shares of Common Stock included
in the Reoffer Prospectus represents shares of Common Stock (i) issued to the selling stockholders pursuant to equity awards or
(ii) issuable pursuant to stock options granted to the selling stockholders, and does not necessarily represent a present intention
to sell any or all such shares of Common Stock.
PART
I
INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS
Item
1. |
Plan
Information. |
The
Company will provide each recipient of a grant under the 2015 Plan (the “Recipients”) with documents that contain
information related to the 2015 Plan, and other information including, but not limited to, the disclosure required by Item 1 of
Form S-8, which information is not required to be and is not being filed as a part of this Registration Statement on Form S-8 (the
“Registration Statement”) or as prospectuses or prospectus supplements pursuant to Rule 424 under the Securities
Act. The foregoing information and the documents incorporated by reference in response to Item 3 of Part II of this Registration
Statement, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act. A Section 10(a)
prospectus will be given to each Recipient who receives shares of Common Stock covered by this Registration Statement, in accordance
with Rule 428(b)(1) under the Securities Act.
Item
2. |
Registrant
Information and Employee Plan Annual Information. |
We
will provide to each Recipient a written statement advising of the availability of documents incorporated by reference in Item
3 of Part II of this Registration Statement (which documents are incorporated by reference in this Section 10(a) prospectus)
and of documents required to be delivered pursuant to Rule 428(b) under the Securities Act without charge and upon written
or oral request by contacting:
Kate
Beebe DeVarney, Ph.D., President and Chief Operating Officer
Titan
Pharmaceuticals, Inc.
400
Oyster Point Blvd., Suite 505
South
San Francisco, California 94080
REOFFER
PROSPECTUS
1,464,541
Shares
Common
Stock Issued Under the 2015 Plan and
Certain
Awards Granted Outside of the 2015 Plan
This
Reoffer Prospectus relates to the public resale, from time to time, of an aggregate of 1,464,541 shares (the “Shares”)
of our common stock, $0.001 par value per share (the “Common Stock”) by certain securityholders identified herein
in the section entitled “Selling Securityholders.” Such shares have been previously issued pursuant to the Company’s
Amended and Restated 2015 Omnibus Equity Incentive Plan or may be acquired in connection with stock options granted to the Selling
Securityholders. You should read this prospectus carefully before you invest in our Common Stock.
Such
resales shall take place on The Nasdaq Capital Market, or such other stock market or exchange on which our Common Stock may be
listed or quoted, in negotiated transactions or otherwise, at market prices prevailing at the time of the sale or at prices otherwise
negotiated (see “Plan of Distribution” starting on page 6 of this prospectus). We will receive no part of the proceeds
from sales made under this Reoffer Prospectus. The Selling Securityholders will bear all sales commissions and similar expenses.
Any other expenses incurred by us in connection with the registration and offering and not borne by the Selling Securityholders
will be borne by us.
This
Reoffer Prospectus has been prepared for the purposes of registering our shares of Common Stock under the Securities Act to allow
for future sales by Selling Securityholders on a continuous or delayed basis to the public without restriction. We have not entered
into any underwriting arrangements in connection with the sale of the shares covered by this Reoffer Prospectus. The Selling Securityholders
identified in this Reoffer Prospectus, or their pledgees, donees, transferees or other successors-in-interest, may offer the shares
covered by this Reoffer Prospectus from time to time through public or private transactions at prevailing market prices, at prices
related to prevailing market prices or at privately negotiated prices.
Investing
in our Common Stock involves risks. See “Risk Factors” beginning on page 3 of this Reoffer Prospectus. These are speculative
securities.
Our
Common Stock trades on The Nasdaq Capital Market under the symbol “TTNP.” On October 23, 2023, the last reported
sale price of our Common Stock on The Nasdaq Capital Market was $0.34 per share.
NEITHER
THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR DETERMINED
IF THIS PROSPECTUS IS TRUTHFUL OR COMPLETE. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
The
date of this prospectus is October 24, 2023
TABLE
OF CONTENTS
CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS
This prospectus contains “forward-looking statements” that involve substantial risks
and uncertainties. All statements other than statements of historical facts contained
in this prospectus, including statements regarding our future results of operations
and financial position, strategy and plans, and our expectations for future operations,
are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Exchange Act. We have attempted to identify forward-looking statements by
terminology including “anticipates,” “believes,” “can,” “continue,” “could,” “estimates,”
“expects,” “intends,” “may,” “plans,” “potential,” “predicts,” “should,” or “will”
or the negative of these terms or other comparable terminology. Although we do not
make forward looking statements unless we believe we have a reasonable basis for doing
so, we cannot guarantee their accuracy. Forward-looking statements included or incorporated
by reference in this prospectus or our other filings with the SEC include, but are
not necessarily limited to, those relating to uncertainties relating to:
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our ability to raise capital when needed; |
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difficulties or delays in the product development process, including the results of
preclinical studies or clinical trials; |
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financing and strategic agreements and relationships; |
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● |
difficulties or delays in the regulatory approval process; |
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adverse side effects or inadequate therapeutic efficacy of our drug candidates that
could slow or prevent product development or commercialization; |
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● |
dependence on third-party suppliers; |
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● |
uncertainties relating to manufacturing, sales, marketing and distribution of our
drug candidates that may be successfully developed and approved for commercialization; |
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● |
the uncertainty of protection for our patents and other intellectual property or trade
secrets; and |
These statements are only predictions and involve known and unknown risks, uncertainties
and other factors, including the risks outlined under “Risk Factors” or elsewhere
in this prospectus, which may cause our or our industry’s actual results, levels of activity, performance or achievements expressed or implied
by these forward-looking statements.
Forward-looking statements should not be read as a guarantee of future performance
or results, and will not necessarily be accurate indications of the times at, or by
which, that performance or those results will be achieved. Forward-looking statements
are based on information available at the time they are made and/or management’s good faith belief as of that time with respect to future events, and are subject
to risks and uncertainties that could cause actual performance or results to differ
materially from what is expressed in or suggested by the forward-looking statements.
Forward-looking statements speak only as of the date they are made. You should not
put undue reliance on any forward-looking statements. We assume no obligation to update
forward-looking statements to reflect actual results, changes in assumptions or changes
in other factors affecting forward-looking information, except to the extent required
by U.S. federal securities laws. If we do update one or more forward-looking statements,
no inference should be drawn that we will make additional updates with respect to
those or other forward-looking statements. We caution you not to give undue weight
to such projections, assumptions and estimate.
PROSPECTUS SUMMARY
The SEC allows us to “incorporate by reference” certain information that we file with the SEC, which means that we can disclose important
information to you by referring you to those documents. The information incorporated
by reference is considered to be part of this prospectus, and information that we
file later with the SEC will update automatically, supplement and/or supersede the
information disclosed in this prospectus. Any statement contained in a document incorporated
or deemed to be incorporated by reference in this prospectus shall be deemed to be
modified or superseded for purposes of this prospectus to the extent that a statement
contained in this prospectus or in any other document that also is or is deemed to
be incorporated by reference in this prospectus modifies or supersedes such statement.
Any such statement so modified or superseded shall not be deemed, except as so modified
or superseded, to constitute a part of this prospectus. You should read the following
summary together with the more detailed information regarding our company, our Common
Stock and our financial statements and notes to those statements appearing elsewhere
in this prospectus or incorporated herein by reference.
Our Company
Overview of our Business
We are a pharmaceutical company developing therapeutics utilizing a proprietary long-term drug delivery platform, ProNeura®, for the treatment of select chronic diseases for which steady state delivery of
a drug has the potential to provide an efficacy and/or safety benefit. ProNeura consists
of a small, solid implant made from a mixture of ethylene-vinyl acetate, or EVA, and
a drug substance. The resulting product is a solid matrix that is designed to be administered
subdermally in a brief, outpatient procedure and is removed in a similar manner at
the end of the treatment period.
Our first product based on the ProNeura technology is Probuphine® (buprenorphine implant), which is approved in
the United States, Canada and the European Union, or EU, for the maintenance treatment
of opioid use disorder in clinically stable patients taking 8 mg or less a day of
oral buprenorphine. While Probuphine continues to be commercialized in Canada and
the EU (as Sixmo™) by other companies that have either licensed or acquired the rights
from us, we discontinued commercialization of the product in the United States during
the fourth quarter of 2020 to allow us to focus our limited resources on other product
development programs.
In December 2021, we announced our intention to work with our financial advisor to explore strategic
alternatives to enhance stockholder value, potentially including an acquisition, merger,
reverse merger, sale of assets, licensing or other business combination transaction.
In June 2022, we implemented a plan to reduce expenses and conserve capital that included a
company-wide reduction in salaries and a scale back of certain operating expenses
to enable us to maintain sufficient resources as we pursued potential strategic alternatives.
In July 2022, David E. Lazar and Activist Investing LLC acquired an approximately 25% ownership
interest in our company, filed a proxy statement and nominated six additional directors,
each of whom was elected to our board of directors at a special meeting of stockholders
held on August 15, 2022 (the “Special Meeting”). The exploration and evaluation of possible strategic
alternatives by the Board has continued following the Special Meeting. To date, we
have no commitments with respect to any such strategic alternatives. Following the
election of new directors at the Special Meeting, Dr. Marc Rubin was replaced as our
Executive Chairman and Mr. Lazar assumed the position of Chief Executive Officer. In connection with Dr. Rubin’s cessation of employment as Executive Chairman, we agreed to make aggregate severance
payments to him of approximately $400,000, of which approximately $247,000 had been
paid as of March 31, 2023. In December 2022, we implemented additional cost reduction measures including a reduction in our
workforce. On June 21, 2023, Mr. Lazar entered into and completed a Share Transfer Agreement with Choong Choon Hau,
pursuant to which Mr. Lazar sold all of his beneficial ownership interests in our company (excluding equity
based compensation) to Mr. Choong.
On July 26, 2023, the Company entered into an asset purchase agreement (the “Asset Purchase Agreement”) with Fedson,
Inc., a Delaware corporation (“Fedson”) for the sale of certain ProNeura assets including
Titan’s portfolio of drug addiction products, in addition to other early development programs
based on the ProNeura drug delivery technology (the “ProNeura Assets”). The Company’s addiction portfolio consists of the Probuphine and Nalmefene implant programs. The
ProNeura Assets constitute only a portion of Titan’s assets. On August 25, 2023, the Company entered into an Amendment and Extension Agreement with respect to the Asset Purchase Agreement, pursuant to which Fedson agreed to purchase the ProNeura Assets for a purchase price of $2,000,000, consisting of (i) $500,000 in readily available funds, to be paid in full on the
Closing Date (the “Closing Cash”), (ii) $500,000 in the form of a promissory note
due and payable on October 1, 2023 (the “Cash Note”) and (iii) $1,000,000 in the form of a promissory note due
and payable on January 1, 2024 (the “Escrow Note”, and together with the Closing Cash and the Cash Note, the
“Closing Consideration”). On the Closing Date, Fedson delivered to the Company a written guaranty by a principal of Fedson of all of Fedson’s obligations under both the Cash Note and Escrow Note. In consideration for an extension of the Closing Date to September 1, 2023, Fedson paid the Company an advance of $250,000 against the Closing Consideration. On September 29, 2023, and in accordance with the terms of the Cash Note, Fedson paid the Company
$5,000 to extend the payment date of the Cash Note to November 1, 2023.
In August 2023, the Company received $500,000 in funding in exchange for the issuance of a convertible promissory
note for that principal amount to Choong Choon Hau (the “Hau Promissory Note”). Pursuant
to the Hau Promissory Note, the principal amount will accrue interest at a rate of
10% per annum and will be payable monthly. All principal and accrued interest shall
be due and payable on January 1, 2024, unless extended as provided. All or part of the Hau Promissory Note can be
converted into our Common Stock at a conversion price of $0.5712 per share from time to time following the issuance date and ending on the maturity
date.
On September 13, 2023, the Company entered into a Securities Purchase Agreement (the “Purchase Agreement”)
with The Sire Group Ltd. (“Sire Group” or the “Investor”), pursuant to which the Company
agreed to issue 950,000 shares of Series AA Convertible Preferred Stock, par value
$0.001 per share to Sire Group at a price of $10.00 per share, for an aggregate purchase price of $9,500,000. The purchase price consisted of (i) $5 million in cash at closing and (ii) $4.5 million in the form of a promissory
note from Sire Group, personally guaranteed by a principal of Sire Group, due and
payable on September 23, 2023, subject to two 10-day extensions which include additional payments of $50,000
for each extension. Sire Group remitted the $4.5 million principal under the promissory note on September 26, 2023.
The Offering
Outstanding Common Stock: |
|
15,016,295 shares of our Common Stock are outstanding as of October 24, 2023. |
|
|
|
Common Stock Offered: |
|
Up to 1,464,541 shares of Common Stock for sale by the Selling Securityholders (which include our executive officers and directors) for their own account pursuant
to the 2015 Plan. |
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|
|
Selling Securityholders: |
|
The Selling Securityholders are set forth in the section entitled “Selling Securityholders” of this Reoffer Prospectus on page 4. The amount of securities to be offered or resold by means of the Reoffer Prospectus by the designated Selling Securityholders may not exceed, during any three-month period, the amount specified in Rule 144(e). |
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|
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Use of proceeds: |
|
We will not receive any proceeds from the sale of our Common Stock by the Selling Securityholders. We would, however, receive proceeds upon the exercise of the stock options by those
who receive options under the 2015 Plan and exercise such options for cash. Any cash proceeds will be used by us for general
corporate purposes. |
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|
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Risk Factors: |
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The securities offered hereby involve a high degree of risk. See “Risk Factors.” |
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|
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Nasdaq Capital Market trading symbol |
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“TTNP” |
RISK FACTORS
An investment in our securities involves a high degree of risk. You should carefully consider the risks, uncertainties and assumptions discussed in Item
1A., “Risk Factors” of our annual report on Form 10-K for the fiscal year ended December 31, 2022, in Item 1A., “Risk Factors” of our quarterly reports on Form 10-Q for the
quarters ended March 31, 2023 and June 30, 2023, and in other documents that we subsequently file with the SEC that update,
supplement or supersede such information, which documents are incorporated by reference
into this Reoffer Prospectus. Additional risks not presently known to us or which we consider immaterial based
on information currently available to us may also materially adversely affect us.
If any of the events anticipated by the risks described occur, our results of operations
and financial condition could be adversely affected, which could result in a decline
in the market price of our common stock, causing you to lose all or part of your investment.
USE OF PROCEEDS
The shares which may be sold under this Reoffer Prospectus will be sold for the respective accounts of each of the Selling Securityholders listed
herein (which includes our executive officers and directors). Accordingly, we will
not realize any proceeds from the sale of the shares of our Common Stock. We will
receive proceeds from the exercise of the options; however, no assurance can be given
as to when or if any or all of the options will be exercised. If any options are exercised,
the proceeds derived therefrom will be used for working capital and general corporate
purposes. All expenses of the registration of the shares will be paid by us. See “Selling
Securityholders” and “Plan of Distribution.”
SELLING SECURITYHOLDERS
We are registering for resale the shares covered by this prospectus to permit the
Selling Securityholders identified below and their pledgees, donees, transferees and
other successors-in-interest that receive their securities from a Selling Securityholder
as a gift, partnership distribution or other non-sale related transfer after the date
of this prospectus to resell the shares when and as they deem appropriate. The Selling
Securityholders acquired, or may acquire, these shares from us pursuant to the 2015 Plan. The shares may not be sold or otherwise transferred by the Selling Securityholders
unless and until the applicable awards vest and are exercised, as applicable, in accordance
with the terms and conditions of the 2015 Plan.
The following table sets forth:
| ● | the name of each Selling Securityholder; |
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● |
the position(s), office or other material relationship with our company and its predecessors
or affiliates, over the last three years of each Selling Securityholder; |
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● |
the number and percentage of shares of our Common Stock that each Selling Securityholder
beneficially owned as of October 24, 2023 prior to the offering for resale of the shares under this prospectus; |
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● |
the number of shares of our Common Stock that may be offered for resale for the account
of each Selling Securityholder under this prospectus; and |
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● |
the number and percentage of shares of our Common Stock to be beneficially owned by
each Selling Securityholder after the offering of the resale shares (assuming all
of the offered resale shares are sold by such Selling Securityholder). |
Information with respect to beneficial ownership is based upon information obtained
from the Selling Securityholders. Because the Selling Securityholders may offer all
or part of the shares of Common Stock, which they own pursuant to the offering contemplated
by this Reoffer Prospectus, and because its offering is not being underwritten on a firm commitment basis, no
estimate can be given as to the amount of shares that will be held upon termination
of this offering.
The number of shares in the column “Number of Shares Being Offered” represents the shares of our Common Stock that each Selling Securityholder may offer
under this prospectus (“Shares”). We do not know how long the Selling Securityholders
will hold the Shares before selling them or how many Shares they will sell. The shares of our Common Stock offered by this prospectus may be offered
from time to time by the Selling Securityholders listed below. We cannot assure you
that any of the Selling Securityholders will offer for sale or sell any or all of
the shares of Common Stock offered by them by this prospectus.
| |
Number
of
Shares Beneficially Owned Prior
to
Offering (1) | | |
Number
of Shares Being | | |
Number of
Shares Beneficially
Owned After
Offering (2)
| |
Securityholders | |
Number | | |
Percent (%) | | |
Offered | | |
Number | | |
Percent (%) | |
David E. Lazar (3) | |
| 100,000 | | |
| * | | |
| 100,000 | | |
| - | | |
| -% | |
Kate Beebe DeVarney, Ph.D. (4) | |
| 356,533 | | |
| 2.3 | | |
| 356,533 | | |
| - | | |
| -% | |
Avraham Ben-Tzvi (5) | |
| 175,000 | | |
| 1.2 | | |
| 175,000 | | |
| - | | |
| -% | |
Eric Greenberg (6) | |
| 175,000 | | |
| 1.2 | | |
| 175,000 | | |
| - | | |
| -% | |
Matthew C. McMurdo (7) | |
| 175,000 | | |
| 1.2 | | |
| 175,000 | | |
| - | | |
| -% | |
David Natan (8) | |
| 175,000 | | |
| 1.2 | | |
| 175,000 | | |
| - | | |
| -% | |
Brian Crowley (9) | |
| 133,008 | | |
| * | | |
| 133,008 | | |
| - | | |
| -% | |
Peter L. Chasey (10) | |
| 175,000 | | |
| 1.2 | | |
| 175,000 | | |
| - | | |
| -% | |
Total: | |
| 1,464,541 | | |
| | | |
| | | |
| | | |
| | |
| * | Indicates beneficial ownership of less than 1% of the outstanding
Common Stock |
(1) |
The number and percentage of shares beneficially owned is determined in accordance
with Rule 13d-3 of the Securities Exchange Act of 1934, as amended, and the information is not
necessarily indicative of beneficial ownership for any other purpose. Under such rule,
beneficial ownership includes any shares as to which the Selling Securityholder has
sole or shared voting power or investment power and also any shares which the Selling
Securityholder has the right to acquire within 60 days. Applicable percentage ownership
is based on 15,016,295 shares of Common Stock outstanding as of October 24, 2023. |
(2) |
Assumes that all shares of Common Stock to be offered, as set forth above, are sold
pursuant to this offering and that no other shares of Common Stock are acquired or
disposed of by the Selling Securityholders prior to the termination of this offering.
Because the Selling Securityholders may sell all, some or none of their shares of
Common Stock or may acquire or dispose of other shares of Common Stock, no reliable
estimate can be made of the aggregate number of shares of Common Stock that will be
sold pursuant to this offering or the number or percentage of shares of Common Stock
that each Selling Securityholder will own upon completion of this offering. |
(3) |
Mr. Lazar is our Chief Executive
Officer and our former Chairman of the Board. |
(4) |
Dr. Beebe DeVarney is our President and Chief Operating Officer and a member of the Board. The shares of Common Stock beneficially owned include 306,553 shares of common stock subject to options exercisable within 60 days of October 24, 2023. |
(5) |
Mr. Ben-Tzvi is a member of the Board. The shares of Common Stock beneficially owned include 125,000 shares of common stock subject to options exercisable within 60 days of October 24, 2023. |
(6) |
Mr. Greenberg is a member of the Board. The shares of Common Stock beneficially owned include 125,000 shares of common stock subject to options exercisable within 60 days of October 24, 2023. |
(7) |
Mr. McMurdo is a member of the Board. The shares of Common Stock beneficially owned include 125,000 shares of common stock subject to options exercisable within 60 days of October 24, 2023. |
(8) |
Mr. Natan is a member of the Board. The shares of Common Stock beneficially owned include 125,000 shares of common stock subject to options exercisable within 60 days of October 24, 2023. |
(9) |
Mr. Crowley is our Sr. Vice President, Finance. The shares of Common Stock beneficially
owned include 83,008 shares of common stock subject to options exercisable within 60 days of October 24, 2023. |
(10) |
Mr. Chasey is a former member of the Board. The shares of Common Stock beneficially owned include 125,000 shares of common stock subject to options exercisable within 60 days of October 24, 2023. |
PLAN OF DISTRIBUTION
We are registering the Shares covered by this prospectus to permit the Selling Stockholders
to conduct public secondary trading of these Shares from time to time after the date
of this prospectus. We will not receive any of the proceeds of the sale of the Shares
offered by this prospectus. The aggregate proceeds to the Selling Stockholders from
the sale of the Shares will be the purchase price of the Shares less any discounts
and commissions. We will not pay any brokers’ or underwriters’ discounts and commissions in connection with the registration and sale of the Shares
covered by this prospectus. The Selling Stockholders reserve the right to accept and,
together with their respective agents, to reject, any proposed purchases of Shares
to be made directly or through agents.
The Shares offered by this prospectus may be sold from time to time to purchasers:
|
● |
directly by the Selling Stockholders, or |
|
● |
through underwriters, broker-dealers or agents, who may receive compensation in the
form of discounts, commissions or agent’s commissions from the Selling Stockholders or the purchasers of the Shares. |
Any underwriters, broker-dealers or agents who participate in the sale or distribution
of the Shares may be deemed to be “underwriters” within the meaning of the Securities
Act. As a result, any discounts, commissions or concessions received by any such broker-dealer
or agents who are deemed to be underwriters will be deemed to be underwriting discounts
and commissions under the Securities Act. Underwriters are subject to the prospectus
delivery requirements of the Securities Act and may be subject to certain statutory
liabilities under the Securities Act and the Securities Exchange Act of 1934, as amended
(the “Exchange Act”). We will make copies of this prospectus available to the Selling
Stockholders for the purpose of satisfying the prospectus delivery requirements of
the Securities Act. To our knowledge, there are currently no plans, arrangements or
understandings between the Selling Stockholders and any underwriter, broker-dealer
or agent regarding the sale of the Shares by the Selling Stockholders.
The Shares may be sold in one or more transactions at:
|
● |
prevailing market prices at the time of sale; |
|
● |
prices related to such prevailing market prices; |
|
● |
varying prices determined at the time of sale; or |
These sales may be effected in one or more transactions:
|
● |
on any national securities exchange or quotation service on which the Shares may be
listed or quoted at the time of sale, including the The Nasdaq Capital Market; |
|
● |
in the over-the-counter market; |
|
● |
in transactions otherwise than on such exchanges or services or in the over-the-counter
market; |
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● |
any other method permitted by applicable law; or |
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● |
through any combination of the foregoing. |
These transactions may include block transactions or crosses. Crosses are transactions
in which the same broker acts as an agent on both sides of the trade.
At the time a particular offering of the Shares is made, a prospectus supplement,
if required, will be distributed, which will set forth the name of the Selling Stockholders,
the aggregate amount of Shares being offered and the terms of the offering, including,
to the extent required, (1) the name or names of any underwriters, broker-dealers
or agents, (2) any discounts, commissions and other terms constituting compensation
from the Selling Stockholders and (3) any discounts, commissions or concessions allowed
or reallowed to be paid to broker-dealers.
The Selling Stockholders will act independently of us in making decisions with respect
to the timing, manner, and size of each resale or other transfer. There can be no
assurance that the Selling Stockholders will sell any or all of the Shares under this
prospectus. Further, we cannot assure you that the Selling Stockholders will not transfer,
distribute, devise or gift the Shares by other means not described in this prospectus.
In addition, any Shares covered by this prospectus that qualify for sale under Rule 144 of the Securities Act may be sold under Rule 144 rather than under this prospectus. The Shares may be sold in some states only through
registered or licensed brokers or dealers. In addition, in some states the Shares
may not be sold unless they have been registered or qualified for sale or an exemption
from registration or qualification is available and complied with.
The Selling Stockholders and any other person participating in the sale of the Shares
will be subject to the Exchange Act. The Exchange Act rules include, without limitation,
Regulation M, which may limit the timing of purchases and sales of any of the Shares
by the Selling Stockholders and any other person. In addition, Regulation M may restrict
the ability of any person engaged in the distribution of the Shares to engage in market-making
activities with respect to the particular Shares being distributed. This may affect
the marketability of the Shares and the ability of any person or entity to engage
in market-making activities with respect to the Shares.
The Selling Stockholders may indemnify any broker or underwriter that participates
in transactions involving the sale of the Shares against certain liabilities, including
liabilities arising under the Securities Act.
LEGAL MATTERS
The validity of the issuance of the securities offered by this prospectus will be
passed upon for us by Olshan Frome Wolosky LLP, New York, New York.
EXPERTS
The financial statements of Titan Pharmaceuticals, Inc. included in our annual report
on Form 10-K for the fiscal years ended December 31, 2022 and 2021 have been audited by WithumSmith+Brown, PC, independent registered public
accountants, as set forth in their reports thereon, included therein, and incorporated
herein by reference in this prospectus, which report includes an explanatory paragraph about the existence of substantial
doubt concerning the Company’s ability to continue as a going concern, and elsewhere in the registration statement. Such financial statements are incorporated
herein by reference in reliance upon such reports given on the authority of said firm
as experts in accounting and auditing.
DISCLOSURE OF COMMISSION POSITION ON INDEMNIFICATION
FOR SECURITIES ACT LIABILITIES
Insofar as indemnification for liabilities arising under the Securities Act may be
permitted to directors, officers or persons controlling the registrant, the registrant
has been informed that in the opinion of the Commission such indemnification is against
public policy as expressed in the Securities Act and is therefore unenforceable.
WHERE YOU CAN FIND MORE INFORMATION
We file annual reports, quarterly and
current reports, proxy statements and other information with the SEC. The SEC maintains an Internet website that contains reports,
proxy and information statements, and other information regarding issuers that file electronically with the SEC at www.sec.gov.
We maintain an Internet website at www.titanpharm.com. All of our reports filed with
the SEC (including Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q, Current
Reports on Form 8-K and proxy statements) are accessible through the Investor Relations
section of our website, free of charge, as soon as reasonably practicable after electronic
filing. The reference to our website in this prospectus is an inactive textual reference
only and is not a hyperlink. The contents of our website are not part of this prospectus,
and you should not consider the contents of our website in making an investment decision
with respect to our securities.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents by Reference
The following documents previously filed with the Commission by the Company are incorporated by reference herein:
|
(1) |
The Annual Report on Form 10-K for the year ended December 31, 2022, filed with the Commission on March 31, 2023; |
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|
|
|
(2) |
The Quarterly Reports on Form 10-Q (i) for the fiscal quarter ended March 31, 2023, filed with the Commission on May 15, 2023 and (ii) for the fiscal quarter ended June 30, 2023, filed with the Commission on August 14, 2023; |
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|
(3) |
The Current Reports on Form 8-K (other than information furnished rather than filed) filed with the Commission on January 6, 2023, February 9, 2023, March 3, 2023, March 22, 2023, April 11, 2023, June 6, 2023, June 29, 2023, July 7, 2023, July 28, 2023, August 30, 2023, September 8, 2023, September 18, 2023, as amended, and October 16, 2023; and |
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|
(4) |
The Definitive Proxy Statement on Schedule 14A, filed with the SEC on May 19, 2023; and |
|
|
|
|
(5) |
The description of common stock contained in Forms 8 and 8-A previously filed with the Commission and any amendments or reports filed for the purpose of updating such description. |
All documents filed by the Company pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934 (other than documents
or information deemed to have been “furnished” and not “filed”) after the date hereof
and before the filing of a post-effective amendment that indicates that all securities
offered hereby have been sold or that deregisters all securities then remaining unsold
shall be deemed to be incorporated by reference herein and to be part hereof from
the date of filing those documents. Any statement contained in any document incorporated
or deemed to be incorporated by reference herein shall be deemed to be modified or
superseded for purposes of this registration statement to the extent that a statement
contained herein or in any subsequently filed document which is or is deemed to be
incorporated by reference herein modifies or supersedes the statement. Any statement
so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this registration statement.
Item 4. Description of Securities.
Not applicable.
Item 5. Interests of Named Experts and Counsel.
None.
Item 6. Indemnification of Directors and Officers.
Amended and Restated Bylaws
Pursuant to our bylaws, our directors and officers will be indemnified to the fullest
extent allowed under the laws of the State of Delaware for their actions in their
capacity as our directors and officers.
We must indemnify any person made a party to any threatened, pending, or completed
action, suit, or proceeding, whether civil, criminal, administrative, or investigative
(“Proceeding”) by reason of the fact that he is or was a director, against judgments,
penalties, fines, settlements and reasonable expenses (including attorney’s fees) (“Expenses”) actually and reasonably incurred by him in connection with such
Proceeding if: (a) he conducted himself in good faith, and: (i) in the case of conduct
in his own official capacity with us, he reasonably believed his conduct to be in
our best interests, or (ii) in all other cases, he reasonably believes his conduct
to be at least not opposed to our best interests; and (b) in the case of any criminal
Proceeding, he had no reasonable cause to believe his conduct was unlawful. We must
indemnify any person made a party to any Proceeding by or in the right of us, by reason
of the fact that he is or was a director, against reasonable expenses actually incurred
by him in connection with such proceeding if he conducted himself in good faith, and:
(a) in the case of conduct in his official capacity with us, he reasonably believed
his conduct to be in our best interests; or (b) in all other cases, he reasonably
believed his conduct to be at least not opposed to our best interests; provided that
no such indemnification may be made in respect of any proceeding in which such person
shall have been adjudged to be liable to us. No indemnification will be made by unless
authorized in the specific case after a determination that indemnification of the
director is permissible in the circumstances because he has met the applicable standard
of conduct. Reasonable expenses incurred by a director who is party to a proceeding
may be paid or reimbursed by us in advance of the final disposition of such Proceeding
in certain cases.
We have the power to purchase and maintain insurance on behalf of any person who is
or was our director, officer, employee, or agent or is or was serving at our request
as an officer, employee or agent of another corporation, partnership, joint venture,
trust, other enterprise, or employee benefit plan against any liability asserted against
him and incurred by him in any such capacity or arising out of his status as such,
whether or not we would have the power to indemnify him against such liability under
the provisions of the amended and restated bylaws.
Delaware Law
Section 145 of the Delaware General Corporation Law provides that a Delaware corporation may
indemnify any persons who are, or are threatened to be made, parties to any threatened,
pending or completed action, suit or proceeding, whether civil, criminal, administrative
or investigative (other than an action by or in the right of such corporation), by
reason of the fact that such person was an officer, director, employee or agent of
such corporation, or is or was serving at the request of such person as an officer,
director, employee or agent of another corporation or enterprise. The indemnity may
include expenses (including attorneys’ fees), judgments, fines and amounts paid in settlement actually and reasonably incurred
by such person in connection with such action, suit or proceeding, provided that such
person acted in good faith and in a manner he or she reasonably believed to be in
or not opposed to the corporation’s best interests and, with respect to any criminal action or proceeding, had no reasonable
cause to believe that his or her conduct was illegal. A Delaware corporation may indemnify
any persons who are, or are threatened to be made, a party to any threatened, pending
or completed action or suit by or in the right of the corporation by reason of the
fact that such person was a director, officer, employee or agent of such corporation,
or is or was serving at the request of such corporation as a director, officer, employee
or agent of another corporation or enterprise. The indemnity may include expenses
(including attorneys’ fees) actually and reasonably incurred by such person in connection with the defense
or settlement of such action or suit provided such person acted in good faith and
in a manner he or she reasonably believed to be in or not opposed to the corporation’s best interests except that no indemnification is permitted without judicial approval
if the officer or director is adjudged to be liable to the corporation. Where an officer
or director is successful on the merits or otherwise in the defense of any action
referred to above, the corporation must indemnify him or her against the expenses
which such officer or director has actually and reasonably incurred. Our amended and
restated certificate of incorporation and amended and restated bylaws provide for
the indemnification of our directors and officers to the fullest extent permitted
under the Delaware General Corporation Law.
Section 102(b)(7) of the Delaware General Corporation Law permits a corporation to provide
in its certificate of incorporation that a director of the corporation shall not be
personally liable to the corporation or its stockholders for monetary damages for
breach of fiduciary duties as a director, except for liability for any:
|
● |
transaction from which the director derives an improper personal benefit; |
|
● |
act or omission not in good faith or that involves intentional misconduct or a knowing
violation of law; |
|
● |
unlawful payment of dividends or redemption of shares; or |
|
● |
breach of a director’s duty of loyalty to the corporation or its stockholders. |
Our amended and restated certificate of incorporation and amended and restated bylaws
include such a provision. Expenses incurred by any officer or director in defending
any such action, suit or proceeding in advance of its final disposition shall be paid
by us upon delivery to us of an undertaking, by or on behalf of such director or officer,
to repay all amounts so advanced if it shall ultimately be determined that such director
or officer is not entitled to be indemnified by us.
Section 174 of the Delaware General Corporation Law provides, among other things, that a director
who willfully or negligently approves of an unlawful payment of dividends or an unlawful
stock purchase or redemption may be held liable for such actions. A director who was
either absent when the unlawful actions were approved, or dissented at the time, may
avoid liability by causing his or her dissent to such actions to be entered in the
books containing minutes of the meetings of the board of directors at the time such
action occurred or immediately after such absent director receives notice of the unlawful
acts.
Indemnification Agreements
As permitted by the Delaware General Corporation Law, we have entered, and intend
to continue to enter, into separate indemnification agreements with each of our directors
and executive officers, that require us to indemnify such persons against any and
all expenses (including attorneys’ fees), witness fees, damages, judgments, fines, settlements and other amounts incurred
(including expenses of a derivative action) in connection with any action, suit or
proceeding, whether actual or threatened, to which any such person may be made a party
by reason of the fact that such person is or was a director, an officer or an employee
of us or any of our affiliated enterprises, provided that such person acted in good
faith and in a manner such person reasonably believed to be in or not opposed to our
best interests and, with respect to any criminal proceeding,
Item 7. Exemption from Registration Claimed.
Not applicable.
Item 8. Exhibits.
Exhibit
No. |
|
Description
of Exhibit |
3.1.1 |
|
Amended and Restated Certificate of Incorporation of the Registrant, as amended (incorporated by reference to Exhibit 3.1 to the Company’s Registration Statement on Form 10 filed on January 14, 2010). |
|
|
|
3.1.2 |
|
Certificate of Amendment to the Restated Certificate of Incorporation dated September 24, 2015 (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K filed on September 28, 2015). |
|
|
|
3.1.3 |
|
Certificate of Amendment to the Restated Certificate of Incorporation dated January 23, 2019 (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K dated January 25, 2019. |
|
|
|
3.1.4 |
|
Certificate of Amendment to the Restated Certificate of Incorporation dated November 30, 2020 (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K dated December 1, 2020). |
|
|
|
3.2 |
|
By-laws of the Registrant (incorporated by reference to Exhibit 3.3 to the Company’s Registration Statement on Form S-3 (File No. 333-221126)). |
|
|
|
3.3 |
|
Amendment to the By-laws of the Registrant dated December 29, 2021 (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K dated December 29, 2021). |
|
|
|
3.4 |
|
Amendment to the By-laws of the Registrant dated July 5, 2022 (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K dated July 5, 2022). |
|
|
|
5.1* |
|
Opinion of Olshan Frome Wolosky LLP, counsel to the Company. |
|
|
|
10.14 |
|
Form of Stock Option Agreement (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K dated September 21, 2022). |
|
|
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10.15 |
|
Fifth Amended and Restated 2015 Omnibus Equity Incentive Plan (incorporated by reference to Exhibit 10.2 to the Company’s Quarterly Report on Form 10-Q for the period ended September 30, 2022). |
|
|
|
23.1* |
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Consent of WithumSmith+Brown, P.C., independent registered public accounting firm. |
|
|
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23.2* |
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Consent of Olshan Frome Wolosky LLP (included in Exhibit 5.1). |
|
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|
24.1* |
|
Powers of Attorney (included on the signature pages to this Registration Statement). |
|
|
|
107* |
|
Filing Fee Table. |
Item 9. Undertakings
(a) The undersigned registrant hereby undertakes:
(1) To file, during any period in which offers or sales are being made, a post-effective
amendment to this registration statement:
(i) To include any prospectus required by Section 10(a)(3) of the Securities Act of 1933;
(ii) To reflect in the prospectus any facts or events arising after the effective
date of the registration statement (or the most recent post-effective amendment thereof)
which, individually or in the aggregate, represent a fundamental change in the information
set forth in the registration statement. Notwithstanding the foregoing, any increase
or decrease in volume of securities offered (if the total dollar value of securities
offered would not exceed that which was registered) and any deviation from the low
or high end of the estimated maximum offering range may be reflected in the form of
prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than
a 20 percent change in the maximum aggregate offering price set forth in the “Calculation
of Registration Fee” table in the effective registration statement; and
(iii) To include any material information with respect to the plan of distribution
not previously disclosed in the registration statement or any material change to such
information in this registration statement.
Provided, however, that the undertakings set forth in paragraphs (a)(1)(i) and (a)(1)(ii) above do
not apply if the information required to be included in a post-effective amendment
by those paragraphs is contained in reports filed with or furnished to the Commission
by the registrant pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated by reference in
the registration statement.
(2) That, for the purpose of determining any liability under the Securities Act of
1933, each such post-effective amendment shall deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities at
that time shall be deemed to be the initial bona fide offering thereof.
(3) To remove from registration by means of a post-effective amendment any of the
securities being registered which remain unsold at the termination of the offering.
(b) The undersigned registrant hereby undertakes
that for the purpose of determining any liability under the Securities Act of 1933, each filing of the registrant’s annual
report pursuant to Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (and, where applicable, each filing of an
employee benefit plan’s annual report pursuant to Section 15(d) of the Securities Exchange Act of 1934) that is
incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the
securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering
thereof.
(c) Insofar as indemnification for liabilities
arising under the Securities Act of 1933 may be permitted to directors, officers and controlling persons of the registrant pursuant
to the foregoing provisions or otherwise, the registrant has been advised that in the opinion of the Commission such indemnification
is against public policy as expressed in the Securities Act of 1933 and is therefore unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director,
officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being registered, the registrant will, unless in the
opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the
question whether such indemnification by it is against public policy as expressed in the Securities Act of 1933, and will be
governed by the final adjudication of such issue.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of
the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in Dubai, United Arab Emirates on the 24th day of October, 2023.
|
TITAN PHARMACEUTICALS, INC. |
|
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By: |
/s/ David E. Lazar |
|
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Name: |
David E. Lazar |
|
|
Title: |
Chief Executive Officer |
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, each director and officer whose signature appears
below constitutes and appoints each of David E. Lazar and Katherine Beebe DeVarney, Ph.D. his true and lawful attorney-in-fact and agent, with full power of substitution and
re-substitution, to sign in any and all capacities any and all amendments or post-effective
amendments to this registration statement, and to sign any and all additional registration
statements relating to the same offering of securities of the Registration Statement
that are filed pursuant to Rule 462(b) of the Securities Act, and to file the same with all exhibits thereto and other
documents in connection therewith with the Securities and Exchange Commission, granting
such attorney-in-fact and agent full power and authority to do all such other acts
and execute all such other documents as he may deem necessary or desirable in connection
with the foregoing, as fully as the undersigned may or could do in person, hereby
ratifying and confirming all that such attorney-in-fact and agent may lawfully do
or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this registration statement
has been signed by the following persons in the capacities and on the dates indicated.
Name |
|
Title |
|
Date |
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|
/s/ David E. Lazar |
|
Chief Executive Officer |
|
October 24, 2023 |
David Lazar |
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Principal Executive Officer |
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Chairman of the Board of Directors |
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Seow Gim Shen |
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/s/ Katherine Beebe DeVarney, Ph.D. |
|
President, Chief Operating Officer and Director |
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October 24, 2023 |
Katherine Beebe DeVarney, Ph.D. |
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|
/s/ Avraham Ben-Tzvi, Adv. |
|
Director |
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October 24, 2023 |
Avraham Ben-Tzvi, Adv. |
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Director |
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Brynner Chiam |
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/s/ Eric Greenberg |
|
Director |
|
October 24, 2023 |
Eric Greenberg |
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|
/s/ Matthew C. McMurdo, Esq. |
|
Director |
|
October 24, 2023 |
Matthew C. McMurdo, Esq. |
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/s/ David Natan |
|
Director |
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October 24, 2023 |
David Natan |
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/s/ Brian Crowley |
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Vice President, Finance (Principal Accounting Officer) |
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October 24, 2023 |
Brian Crowley |
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Exhibit
5.1
Titan
Pharmaceuticals, Inc.
400
Oyster Point Blvd., Suite 505
South
San Francisco, CA 94080
| Re: | Registration
Statement on Form S-8 |
Ladies
and Gentlemen:
We
have acted as counsel to Titan Pharmaceuticals, Inc., a Delaware corporation (the “Company”), in connection with the filing
of its registration statement on Form S-8 (the “Registration Statement”) with the Securities and Exchange Commission (the
“Commission”), relating to the registration of 2,492,424 shares (the “Shares”) of the Company’s common
stock, par value $0.001 per share (the “Common Stock”) issuable pursuant to the terms of and in the manner set forth in the
Company’s Fifth Amended and Restated 2015 Omnibus Equity Incentive Plan, as amended, effective as of June 29, 2023 (the “2015
Plan”).
This
opinion letter is being delivered at the request of the Company and in accordance with the requirements of Item 601(b)(5) of Regulation
S-K promulgated under the Securities Act of 1933, as amended (the “Securities Act”).
We
advise you that we have examined executed originals or copies certified or otherwise identified to our satisfaction of (i) the Registration
Statement, (ii) the Company’s Amended and Restated Certificate of Incorporation and the Company’s Amended and Restated Bylaws,
each as amended to date, (iii) the 2015 Plan, and (iv) corporate proceedings of the Company, and such other documents, instruments and
certificates of officers and representatives of the Company and of public officials, and we have made such examination of fact and law,
as we have deemed necessary or appropriate for purposes of the opinion expressed below. As to questions of fact material to this opinion,
we have relied on certificates or comparable documents of officers and representatives of the Company and of public officials.
We
have assumed for purposes of rendering the opinion set forth herein, without verification, the genuineness of all signatures, the legal
capacity of all natural persons to execute and deliver documents, the authenticity and completeness of documents submitted to us as originals
and the completeness and conformity with authentic original documents of all documents submitted to us as copies.
On
the basis of the foregoing and in reliance thereon and subject to the assumptions, qualifications and limitations set forth herein, we
advise you that in our opinion, the Shares, when issued and paid for pursuant to the terms of and in the manner set forth in the 2015
Plan, will be duly and validly issued, fully paid and non-assessable.
October
24, 2023
Page 2
We
are members of the Bar of the State of New York. We express no opinion as to the effect of any laws other than the laws of the State
of New York, the General Corporation Law of the State of Delaware and the Federal laws of the United States of America, each as in effect
on the date hereof.
This
opinion speaks only at and as of its date and we assume no obligation to revise or supplement this opinion to reflect any facts or circumstances
that may hereafter come to our attention or any changes in fact or law that may hereafter occur.
We
hereby consent to the filing of this opinion as an exhibit to the Registration Statement. In giving such consent, we do not thereby concede
that our firm is within the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations
of the Commission thereunder.
| Very truly
yours, |
| |
| /s/ Olshan Frome Wolosky LLP |
| |
| OLSHAN FROME WOLOSKY LLP |
Exhibit 23.1
CONSENT
OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We
hereby consent to the incorporation by reference in the Prospectus constituting a part of this Registration Statement on Form S-8 of
our report dated March 31, 2023 (which includes an explanatory paragraph relating to Titan Pharmaceuticals, Inc.’s ability to continue
as a going concern) relating to the financial statements, which is incorporated by reference in that Prospectus. We also consent
to the reference to our firm under the heading “Experts” in the Prospectus.
/s/
WithumSmith+Brown, PC
San
Francisco, California
October
24, 2023
Exhibit
107
Calculation
of Filing Fee Table
Form
S-8
(Form
Type)
Titan
Pharmaceuticals, Inc.
(Exact
name of Registrant as Specified in its Charter)
Table
1 – Newly Registered Securities |
Security
Type |
Security
Class Title |
Fee Calculation Rule |
Amount
Registered(1) |
Proposed
Maximum
Offering Price Per Unit(2) |
Maximum
Aggregate
Offering Price |
Fee
Rate |
Amount
of
Registration Fee |
Equity |
Common
Stock, par value $0.001 per share |
Rule 457(c)
and Rule 457(h) |
2,492,424 |
$0.41 |
$1,021,893.84 |
0.0001476 |
$150.83 |
Total Offering Amounts |
– |
$1,021,893.84 |
– |
$150.83 |
Total Fee Offsets |
– |
– |
– |
– |
Net Fee Due |
– |
– |
– |
$150.83 |
(1) | Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this registration statement also covers any additional securities that may be offered or issued pursuant to the anti-dilution adjustment provisions of the Titan Pharmaceuticals, Inc. 2014 Incentive Plan (the “2014 Plan”) and the Titan Pharmaceuticals, Inc. 2015 Omnibus Equity Incentive Plan (the “2015 Plan”).
This
registration statement on Form S-8 is being filed to register an additional 2,492,424 shares of Common Stock under the 2015 Plan, as
amended effective as of June 29, 2023 (the “Amended 2015 Plan”). |
| |
(2) | Pursuant
to Rule 457(h) under the Securities Act, the proposed maximum offering price, per share
and in the aggregate, were determined upon the basis of the average of the high and low prices
of our Common Stock, reported on the NASDAQ Capital Market on October 20, 2023, in accordance
with Rule 457(c) under the Securities Act. |
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