Item 5.02. Departure of Directors or Certain
Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
Resignation of President, Chief Executive
Officer and Member of the Board of Directors
On December 5, 2017, Synthetic Biologics, Inc.
(the “Company”) issued a press release announcing that effective December 4, 2017, Jeffrey Riley, the Company’s
President and Chief Executive Officer and a member of the Company’s Board of Directors, had resigned from all positions with
the Company for personal reasons.
In addition, on December 5, 2017, Mr. Riley
and the Company entered into a Separation Agreement (the “Separation Agreement”), providing for, among other things,
the acceptance of Mr. Riley’s resignation as the Company’s President and Chief Executive Officer, effective on December
4, 2017, which was also Mr. Riley’s last day of employment with the Company. The Separation Agreement also provides among
other things, that in addition to receiving all accrued obligations, including salary and earned and unused vacation days, Mr.
Riley will receive the following separation benefits: (i) twelve months’ payment of Mr. Riley’s current base salary,
subject to payroll withholdings and deductions, paid on the Company’s regular payroll dates; (ii) a cash bonus for 2017 of
$200,000; and (iii) the right to exercise vested stock options for one (1) year following December 5, 2017. Mr. Riley shall also
be entitled to COBRA continuation coverage, and the Company shall pay the COBRA premium for Mr. Riley for a maximum period of twelve
months after his separation from the Company.
The separation benefits set forth in the Separation
Agreement are further conditioned upon Mr. Riley returning all Company property, complying with his post-termination obligations
under the Separation Agreement, including, but not limited to, complying with the cooperation, non-disparagement and confidentiality
provisions in the Separation Agreement and complying the Proprietary Information, Inventions Non-Solicitation and Non-Competition
Agreement previously entered into with the Company. Mr. Riley has also agreed to release, waive and discharge the Company and certain
others from all claims and other actions, as more fully described in the Separation Agreement.
The foregoing summary of the terms of the Separation
Agreement does not purport to be complete and is subject to, and qualified in its entirety by, the full text of the Separation
Agreement, filed as Exhibit 10.1 to this Current Report on Form 8-K, and is incorporated by reference herein.
Appointment of Interim Chief Executive
Officer
On December 5, 2017, the Company announced
that the Board of Directors had appointed Steven A. Shallcross, the Company’s Chief Financial Officer, to serve as its Interim
Chief Executive Officer. The terms and conditions of Mr. Shallcross’ employment as Interim Chief Executive Officer are being
discussed and once an agreement on compensation with Mr. Shallcross is reached, the Company will provide updated disclosure regarding
his employment arrangements and amended employment agreement.
Mr. Shallcross, age 56, joined the Company
in June 2015 as Chief Financial Officer, Treasurer and Secretary. Mr. Shallcross brings to the Company operational, financial and
international biotech industry experience, as well as an established track record at leading the financial development and strategy
for several publicly traded biotech companies. From May 2013 through May 2015, Mr. Shallcross served as Executive Vice President
and Chief Financial Officer of Nuo Therapeutics, Inc. (formerly Cytomedix, Inc.). In January 2016, Nuo Therapeutics, Inc. filed
a voluntary petition for relief under Chapter 11 of the U.S. Bankruptcy Code in the United States Bankruptcy Court for the District
of Delaware and on April 25, 2016, the Bankruptcy Court entered an order granting Nuo’s plan or reorganization. From July
2012 to May 2013, Mr. Shallcross held the offices of Executive Vice President, Chief Financial Officer and Treasurer of Empire
Petroleum Partners, LLC, a motor fuel distribution company. From July 2011 to March 2012, Mr. Shallcross was Acting Chief Financial
Officer of Senseonics, Inc., a medical device company located in Germantown, MD. From January 2009 to March 2011, he served as
Executive Vice President and Chief Financial Officer of Innocoll AG (formerly privately held Innocoll Holdings, Inc.), a global,
commercial-stage biopharmaceutical company specializing in the development and commercialization of collagen based products. He
also served for four years as the Chief Financial Officer and Treasurer of Vanda Pharmaceuticals, Inc., leading the company through
its successful IPO and follow-on offering and previously served as the Senior Vice President and Chief Financial Officer of Middlebrook
Pharmaceuticals, Inc. (formerly Advancis Pharmaceutical Corporation). In addition, Mr. Shallcross also served as the Chief Financial
Officer of Bering Truck Corporation. He holds an MBA from the University of Chicago’s Booth School of Business, a Bachelor
of Science degree in Accounting from the University of Illinois, Chicago, and is a Certified Public Accountant in the State of
Illinois.
Mr. Shallcross has no direct or indirect material
interest in any transaction required to be disclosed pursuant to Item 404(a) of Regulation S-K, has no family relationships required
to be disclosed pursuant to Item 401(d) of Regulation S-K, and, except as otherwise previously disclosed by the Company, the Company
has not entered into or adopted a material plan or arrangement to which Mr. Shallcross participates or is a party.