The following are some of the stocks making big moves in Wednesday’s pre-market trading (as of 07.30 A.M. ET).

In the Green

iBio, Inc. (IBIO) is up over 86% at $2.14.
Nuvation Bio Inc. (NUVB) is up over 21% at $3.50.
PaySign, Inc. (PAYS) is up over 20% at $4.06.
Hitek Global Inc. (HKIT) is up over 19% at $1.70.
The ONE Group Hospitality, Inc. (STKS) is up over 15% at $4.64.
BriaCell Therapeutics Corp. (BCTX) is up over 11% at $2.82.
Trump Media & Technology Group Corp. (DJT) is up over 10% at $63.80.
Ranpak Holdings Corp. (PACK) is up over 10% at $8.74.
Bragg Gaming Group Inc. (BRAG) is up over 9% at $5.81.
MediciNova, Inc. (MNOV) is up over 8% at $1.48.
NeuroSense Therapeutics Ltd. (NRSN) is up over 7% at $1.83.
Universe Pharmaceuticals INC (UPC) is up over 5% at $1.90.

In the Red

Direct Digital Holdings, Inc. (DRCT) is down over 44% at $14.77.
LuxUrban Hotels Inc. (LUXH) is down over 20% at $1.71.
GameStop Corp. (GME) is down over 17% at $12.84.
Mesoblast Limited (MESO) is down over 14% at $3.37.
Forge Global Holdings, Inc. (FRGE) is down over 10% at $2.36.
BYND Cannasoft Enterprises Inc. (BCAN) is down over 8% at $1.43.
Psyence Biomedical Ltd. (PBM) is down over 7% at $1.04.
Organigram Holdings Inc. (OGI) is down over 6% at $2.51.
Check-Cap Ltd. (CHEK) is down over 6% at $2.30.