RNS Number:2103O
Tepnel Life Sciences PLC
31 July 2003

TEPNEL LIFE SCIENCES PLC ("the Company")


31 July 2003


HOLDING IN COMPANY


The Company received notification on 25 July 2003 from Framlington Investment
Management Limited that it is interested in 7,500,000 ordinary shares of 1p each
in the Company ("Shares"), representing approximately 7.71% of the Company's
issued shares. This is following the sale of 500,000 shares on 21 July 2003.



These shares are registered as follows:



HSBC Global Custody Nominee (UK) Limited a/c 811664



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