RNS No 6945n
CAMBRIDGE ANTIBODY TECHNOLOGY GROUP PLC
11 June 1999


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
 Sir Aaron Klug

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Exercise of options and partial sale of options exercised

7   Number of shares/amount of stock acquired:
62,500

8   Percentage of issued class:
0.249%

9   Number of shares/amount of stock disposed:
27,685

10  Percentage of issued class:
0.110%

11  Class of security:
10p ordinary shares

12  Price per share:
 Option exercise price 15p shares sold at 215p

13  Date of transaction:
June 10 1999

14  Date company informed:
June 10 1999

15  Total holding following this notification:
36,315

16  Total percentage holding of issued class following this notification:
0.145%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Diane Mellett
Company Secretary

END



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