RNS Number:5687V
Cambridge Antibody Tech Group PLC
18 February 2004

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company
Cambridge Antibody Technology


2)   Name of shareholder having a major interest
The Goldman Sachs Group Inc



3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18
As in 2 above


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them

Goldman Sachs Securities (Nominees) Limited             102,404
The Depositary Trust Company, New York                    2,700
Goldman Sachs Securities (Nominees) Limited               1,400
Goldman Sachs International (CREST a/c CREPTEMP)      1,124,332
Goldman Sachs JBWere Managed Funds Limited               88,300


5)   Number of shares/amount of stock acquired
not disclosed


6)   Percentage of issued class
3.22%

7)   Number of shares/amount of stock disposed
None


8)   Percentage of issued class
N/A


9)   Class of security
Ordinary 10 pence shares


10)  Date of transaction
11 February 2004


11)  Date company informed
17 February 2004


12)  Total holding following this notification
1,319,136



13)  Total percentage holding of issued class following this notification
3.22%


14)  Any additional information
None


15)  Name of contact and telephone number for queries
Justin Hoskins 01223 898589




16)  Name and signature of authorised company official responsible for
     making this notification
Diane Mellett, Company Secretary

     Date of notification 17 February 2004





                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

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