FORM 8.3
                                        
    DEALINGS BY PERSONS WITH INTERESTS IN SECURITIES REPRESENTING 1% OR MORE
              (Rule 8.3 of the City Code on Takeovers and Mergers)


1.   KEY INFORMATION

Name of person dealing        BARCLAYS PLC
(Note 1)                      
Company dealt in              CAMBRIDGE ANTIBODY TECHNOLOGY GROUP PLC
Class of relevant security    ORD GBP 0.10
to which the dealings being
disclosed relate (Note 2)
Date of dealing               19 MAY 2006

2.   INTERESTS, SHORT POSITIONS AND RIGHTS TO SUBSCRIBE

(a)  Interests and short positions (following dealing) in the class of relevant
security dealt in (Note 3)

                                                      
                                           
                                                      
                                           
(1) Relevant            850,774    (1.60%)       132,435   (0.25%)
securities
(2) Derivatives         132,435    (0.25%)       337,351   (0.63%)
(other than
options)
(3) Options and               0    (0.00%)             0   (0.00%)
agreements to
purchase/sell
Total                   983,209    (1.85%)       469,786   (0.88%)


(b)  Interests and short positions in relevant securities of the company, other
than the class dealt in (Note 3)

Class of                    Long                     Short
relevant
security:

                  Number                    Number
                                    (%)                       (%)
(1) Relevant                                                        
securities
  
(2) Derivatives                                                     
(other than
options)
  
(3) Options and                                                     
agreements to
purchase/sell
  
Total                                                               


(c)  Rights to subscribe (Note 3)

Class of relevant security:   Details

                              

3.   DEALINGS (Note 4)

(a)  Purchases and sales

Purchase/sale Number of Securities Price per unit
                                   (GBP)
Purchase      30,499               12.9650
Purchase      14,881               13.0020
Sale          4,800                12.9608
Sale          5,000                12.9648
Sale          19,501               12.9683
Sale          30,499               12.9650

(b)  Derivatives transactions (other than options)

Product    Long/Short    Number of Securities  Price Per
name,      (Note 6)      (Note 7)              Unit (GBP)
e.g. CFD
CFD        Short         14,881                13.0020
CFD        Long          4,800                 12.9608
CFD        Long          5,000                 12.9648
CFD        Long          8,573                 12.9904
CFD        Long          4,146                 12.9904
CFD        Long          5,169                 12.9904
CFD        Long          5,537                 12.9955
CFD        Long          9,344                 12.9955


(c)  Options transactions in respect of existing securities

(i)  Writing, selling, purchasing or varying

 
Product name,   Writing,          Number of          Exercise  Type, e.g.      Expiry   Option money
e.g. call       selling,          securities to      price     American,       date     paid/received
option          purchasing,       which the option             European etc.            per unit (Note
                varying etc.      relates (Note 7)                                      5)

                                                         
(ii) Exercising

Product name, e.g.  Number of           Exercise price per
call option         securities          unit (Note 5)
                                        
                                        
                                        

(d)  Other dealings (including new securities) (Note 4)


Nature of transaction Details           Price per unit
(Note 8)                                (if applicable)
                                        (Note 5)
                                        


4.   OTHER INFORMATION

Agreements, arrangements or understandings relating to options or derivatives


Full details of any agreement, arrangement or understanding between the
person disclosing and any other person relating to the voting rights of
any relevant securities under any option referred to on this form or
relating to the voting rights or future acquisition or disposal of any
relevant securities to which any derivative referred to on this form is
referenced.  If none, this should be stated.





Is a Supplemental Form 8 attached? (Note 9)                 NO


Date of disclosure                         22 MAY 2006
Contact name                               BARCLAYS COMPLIANCE
Telephone number                           0207 116 2913
If a connected EFM, name of                
offeree/offeror with which connected
If a connected EFM, state nature of        
connection (Note 10)


Notes

The Notes on Form 8.3 can be viewed on the Takeover Panels website at
www.thetakeoverpanel.org.uk




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