Alpha Cognition Inc. (TSX-V: ACOG) (“Alpha Cognition” or the “Company”), a biopharmaceutical company committed to developing novel therapies with the potential to transform the lives of people with debilitating neurodegenerative disorders, is pleased to announce that it will host its first annual Virtual R&D Day for analysts and investors on Tuesday, June 22, 2021, from 1:00PM to 3:00PM EDT. The program will provide a detailed overview of Alpha Cognition’s development strategy highlighting the Company’s deep pipeline across three therapeutic modalities, including Alzheimer’s Disease, Mild Traumatic Brain Injury (mTBI), and Amyotrophic Lateral Sclerosis (ALS).

In addition to presentations by Alpha Cognition’s management team and a review of the Company’s development programs, the Company’s R&D Day will feature presentations from renowned physicians in the field of Alzheimer’s Disease and TBI, including James E. Galvin, MD, MPH and Dr. Frank Conidi, DO, MS, FAAN, FAHS.

Dr. Galvin is the founding Director of the Comprehensive Center for Brain Health and Professor of Neurology, Psychiatry & Behavioral Sciences at the University of Miami Miller School of Medicine. A board-certified neurologist, Dr. Galvin has authored over 300 scientific publications and three textbooks on healthy brain aging, cognitive health, memory loss, Alzheimer’s disease, Lewy body dementia, and related disorders.

Dr. Frank Conidi is a Boston trained Board Certified sports neurologist/headache specialist. He is the Director of the Florida Center for Headache and Sports Neurology, a tertiary center dedicated to the treatment of patients with chronic/refractory headache disorders and sports related concussion and sports related neurological disorders. He is a nationally recognized expert on sports concussion and the team neurologist for the NHL’s Florida Panthers and has served as a consulting neurologist for the NFL, USTA, NCAA and MLB players. He is also the co-chair of the Florida High School Athletic Concussion committee and has been involved in drafting concussion and TBI guidelines.

After the formal presentation, investors will have an opportunity to ask relevant questions through an interactive Q&A portal. To listen to the webcast or to ask questions during the live event, please pre-register at the following link:

https://event.webcasts.com/starthere.jsp?ei=1465926&tp_key=7db2e2a8a7

An archived version of the webcast and presentation will be available on the Company's Website: https://www.alphacognition.com

About Alpha Cognition Inc.

Alpha Cognition Inc. is a clinical stage, biopharmaceutical company dedicated to developing treatments for under-served neurodegenerative diseases, such as Alzheimer's Dementia and Amyotrophic Lateral Sclerosis (ALS).

ALPHA-1062 is a patented new chemical entity that has demonstrated safety and improved tolerability in human clinical trials. It is being developed as a new generation acetylcholinesterase inhibitor for the treatment of Alzheimer's disease, with minimal gastrointestinal side effects and novel routes of administration. ALPHA-1062's active metabolites are differentiated from donepezil and rivastigmine in that they may sensitize neuronal nicotinic receptors, most notably the alpha-7 subtype, which is known to have a positive effect on cognition. ALPHA-1062 is also being developed in combination with memantine to treat moderate to severe Alzheimer's dementia and in a nasal spray formulation to treat traumatic brain injury.

ALPHA-0602 (Progranulin) is expressed in several cell types in the central nervous system and in peripheral tissues, regulates cell survival and certain inflammatory processes, and plays a major role in regulating lysosomal function and microglial responses to disease. Its use for the treatment of neurodegenerative diseases has been patented by the Company and granted an Orphan Drug Designation.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Forward-looking Statements This news release is not, and under no circumstances is to be construed as, an advertisement or a public offering of securities. No securities commission or similar authority in Canada or in any other jurisdiction has reviewed or in any way passed upon this news release or the merits of the securities described herein and any representation to the contrary is an offence.

This news release includes forward-looking statements within the meaning of applicable securities laws. Except for statements of historical fact, any information contained in this news release may be a forward-looking statement that reflects the Company’s current views about future events and are subject to known and unknown risks, uncertainties, assumptions and other factors that may cause the actual results, levels of activity, performance or achievements to be materially different from the information expressed or implied by these forward-looking statements. In some cases, you can identify forward‐looking statements by the words “may,” “might,” “will,” “could,” “would,” “should,” “expect,” “intend,” “plan,” “objective,” “anticipate,” “believe,” “estimate,” “predict,” “project,” “potential,” “target,” “seek,” “contemplate,” “continue” and “ongoing,” or the negative of these terms, or other comparable terminology intended to identify statements about the future. Forward-looking statements may include statements regarding the Company’s business strategy, market size, potential growth opportunities, capital requirements, clinical development activities, the timing and results of clinical trials, regulatory submissions, potential regulatory approval and commercialization of the technology. Although the Company believes that we have a reasonable basis for each forward-looking statement, we caution you that these statements are based on a combination of facts and factors currently known by us and our expectations of the future, about which we cannot be certain. The Company cannot assure that the actual results will be consistent with these forward-looking statements. These forward‐looking statements speak only as of the date of this news release and the Company undertakes no obligation to revise or update any forward‐looking statements for any reason, even if new information becomes available in the future.

This news release may also contain estimates and other statistical data made by independent parties and by the Company relating to share value and other data about our industry. This data involves a number of assumptions and limitations, and you are cautioned not to give undue weight to such estimates.

For further information: Bristol Investor Relations Stefan Eftychiou 905 326 1888 ext 6 stefan@bristolir.com https://www.alphacognition.com/

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