By Chao Deng and Brad Frischkorn

TOKYO -- Stocks in Asia were mixed in subdued trade Wednesday, with Japanese shares falling on profit-taking while shares in Australia were lifted by a stronger U.S. dollar.

Japan's Nikkei Stock Average ended down 0.6% at 16,082.25 with the dollar hovering around Yen109.81, up from Yen109.65 late Tuesday in New York.

The benchmark index had risen into positive territory earlier as the dollar continued on its recent upward surge and broke above the psychologically important Yen110 mark for the first time in more than six-and-a-half years. But shares later pulled back, weighed by profit-taking.

A slew of the U.S. economic data recently are providing clearer signals to allow an eventual tightening by the Federal Reserve as early as in 2015, making the dollar-denominated assets more attractive to yield seeking investors. A stronger dollar benefits export-dependent countries such as Japan, as it lets producers lower prices on goods they sell overseas and purchase more yen when they repatriate their profits.

Shares of auto maker Toyota Motor hit a fresh 2014 high before closing up 0.6%.

A survey of business sentiment by the Bank of Japan showed that confidence among large Japanese manufacturers rose to a reading of 13, from 12 in June, despite a consumption tax hike in April.

"Labor markets are the tightest they have been since 1992, managers' perception of spare production capacity is that it is tight, and business confidence is higher than expected," said CLSA equity strategist Nicholas Smith. "Combined with a progressively weaker yen and the potential for corporate earnings upgrades and wage hikes, there is little to not like."

Australia's S&P/ASX 200 rose 0.8% to 5,334.10, as the Australian dollar weakened on weaker-than-expected retail sales data in August. Retail sales climbed 0.1% from a month earlier, the Australian Bureau of Statistics said, compared with the 0.4% rise expected by economists.

South Korea's Kospi index was down 1.4%, after an HSBC's purchasing managers' index gauge of manufacturing activity fell to 48.8 in September, from 50.3 in August. Stocks in Taiwan were up 0.3%.

Trading in Asia was quiet with financial markets in Hong Kong and mainland China closed for a public holiday. Hong Kong's stock exchange will also be closed Thursday, while markets in the mainland are closed until Oct. 7 for China's National Day holiday.

China's official manufacturing Purchasing Managers Index -- a key gauge of China's manufacturing -- held steady in September at 51.1 -- suggesting that domestic economic growth has somewhat stabilized but at a modest level. But the data didn't have much impact on regional share trading.

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