By Rhiannon Hoyle

SYDNEY--Rio Tinto PLC's (RIO) head of business development has left the company at a time when the world's second-largest iron-ore producer is working to overhaul its business following massive writedowns last year and its first full-year loss.

Philip Mitchell, who spearheaded mergers and acquisitions talks for the Anglo-Australian mining titan and was in the role for the past six years, is no longer with the company, a person familiar with the situation said. The person didn't give a reason for Mr. Mitchell's departure.

Rio's director of business development for Australia, Matt Halliday, will take over the role on an acting basis, according to Bloomberg News, which cited an internal company memo.

Rio Tinto Chief Executive Sam Walsh last year pledged to pursue greater value for shareholders and slash costs after the company's balance sheet was hit by a sharp drop in commodity prices and more than US$14 billion in impairment charges. That included switching its focus from mergers and acquisitions to cost cutting and asset sales.

Rio's asset writedowns stemmed in large part from costly and poorly timed acquisitions, including the US$38 billion purchase of Canadian aluminum company Alcan at the height of the market in 2007. The company, which cut costs by around US$2 billion last year and will look to strip a further US$3 billion out by the end of this year, will report is full-year 2013 results Thursday.

Write to Rhiannon Hoyle at rhiannon.hoyle@wsj.com

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