RNS Number:0486S
Isotron PLC
13 November 2003


                           SCHEDULE 10
 
             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY

     ISOTRON PLC


2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     AEGON UK PLC GROUP OF COMPANIES


3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

     2 ABOVE


4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

     CHASE NOMINEES LIMITED


5)   Number of shares/amount of stock acquired.

     65,000


6)   Percentage of issued Class

     0.31%

7)   Number of shares/amount of stock disposed

   

8)   Percentage of issued Class



9)   Class of security

     25P ORDINARY


10)  Date of transaction

     NOT KNOWN


11)  Date company informed

     12/11/03


12)  Total holding following this notification

     654,250

               
13)  Total percentage holding of issued class following this notification

     3.10%


14)  Any additional information




15)  Name of contact and telephone number for queries

     MRS C E BRAY
     01793 567900


16)  Name and signature of authorised company official responsible for 
     making this notification


     Date of Notification     13 NOVEMBER 2003


                      This information is provided by RNS
            The company news service from the London Stock Exchange

END
HOLNKNKNPBDDPDD