under Sections 14(e), 14(d), and 20(a) of the Exchange Act and seeks, among other things, an injunction preventing consummation of the proposed transaction with Amgen, rescission of the proposed
transaction or rescissory damages in the event it is consummated, declaratory judgment, and the award of attorneys fees and expenses. On March 24, 2021, Jordan Wilson, a purported stockholder of the Company, commenced an action in the
United States District Court for the District of Delaware, captioned Jordan Wilson v. Five Prime Therapeutics, Inc. et al., Case
No. 1:21-cv-00422-UNA, against the Company and the current members of the Five Prime board of directors (the Wilson
Complaint). The Wilson Complaint asserts claims under Sections 14(d), 14(e), and 20(a) of the Exchange Act and seeks, among other things, an injunction preventing consummation of the proposed transaction with Amgen, filing of a corrected
Schedule 14D-9, rescission of the proposed transaction or rescissory damages in the event it is consummated, declaratory judgment, specific performance, and the award of attorneys fees and expenses. Also
on March 24, 2021, Richard Baker, a purported stockholder of the Company, commenced an action in the United States District Court for the District of Delaware, captioned Richard Baker v. Five Prime Therapeutics, Inc. et al., Case No. 1:21-cv-00423-UNA, against the Company, the current members of the Five Prime board of directors, Amgen, and Purchaser (the
Baker Complaint). The Baker Complaint asserts claims under Sections 14(e), 14(d), and 20(a) of the Exchange Act and seeks, among other things, an injunction preventing consummation of the proposed transaction with Amgen,
rescission of the proposed transaction or rescissory damages in the event it is consummated, filing of a corrected Schedule 14D-9, declaratory judgment, specific performance, and the award of attorneys
fees and expenses. On March 25, 2021, Jacob Wheeler, a purported stockholder of the Company, commenced an action in the United States District Court for the Northern District of California, captioned Jacob Wheeler v. Five Prime Therapeutics,
Inc. et al., Case No. 3:21-cv-02097, against the Company and the current members of the Five Prime board of directors (the Wheeler
Complaint). The Wheeler Complaint asserts claims under Sections 14(e) and 20(a) of the Exchange Act and seeks, among other things, an injunction preventing consummation of the proposed transaction with Amgen, rescission of the
proposed transaction or rescissory damages in the event it is consummated, and the award of attorneys fees and expenses. On March 30, 2021, Alex Ciccotelli, a purported stockholder of the Company, commenced an action in the United States
District Court for the Eastern District of Pennsylvania, captioned Alex Ciccotelli v. Five Prime Therapeutics, Inc. et al., Case No. 2:21-cv-01512, against the
Company, the current members of the Five Prime board of directors, Amgen, and Purchaser (the Ciccotelli Complaint). The Ciccotelli Complaint asserts claims under Sections 14(e), 14(d), and 20(a) of the Exchange Act and seeks,
among other things, an injunction preventing consummation of the proposed transaction with Amgen, filing of a corrected Schedule 14D-9, rescission of the proposed transaction or rescissory damages in the event
it is consummated, declaratory judgment, specific performance, and the award of attorneys fees and expenses. Also on March 30, 2021, Timothy Mills, a purported stockholder of the Company, commenced an action in the United States District
Court for the Southern District of New York, captioned Timothy Mills v. Five Prime Therapeutics, Inc. et al., Case No. 1:21-cv-02718, against the Company and
the current members of the Five Prime board of directors (the Mills Complaint). The Mills Complaint asserts claims for breach of the fiduciary duty of candor/disclosure and for violation of Sections 14(d), 14(e), and 20(a) of
the Exchange Act and seeks, among other things, an injunction preventing consummation of the proposed transaction with Amgen, rescission of the proposed transaction or rescissory damages in the event it is consummated, an accounting by the
defendants for all damages caused to the plaintiff, and the award of attorneys fees and expenses. On April 6, 2021, Esther Kogus, a purported stockholder of the Company, commenced an action in the United States District Court for the
District of Delaware, captioned Esther Kogus v. Five Prime Therapeutics, Inc. et al., Case No. 1:21-cv-00502-UNA, against
the Company and the current members of the Five Prime board of directors (the Kogus Complaint). The Kogus Complaint asserts a claim under Section 14(d) of the Exchange Act and seeks, among other things, an injunction
preventing consummation of the proposed transaction with Amgen, rescission of the proposed transaction or rescissory damages in the event it is consummated, filing of a corrected Schedule 14D-9, declaratory
judgment, and the award of attorneys fees and expenses. Also on April 6, 2021, Satheesh Thomas, a purported stockholder of the Company, commenced an action in the United States District Court for the Northern District of California,
captioned Satheesh Thomas v. Five Prime Therapeutics, Inc. et al., Case No. 3:21-cv-02477, against the Company and the current members of the Five Prime board of
directors (the Thomas Complaint). The Thomas Complaint asserts claims under Sections 14(e) and 20(a) of the Exchange Act and seeks, among other things, an injunction preventing consummation of the proposed transaction with Amgen,
rescission of the proposed transaction or rescissory damages in the event it is consummated, filing of a corrected Schedule 14D-9, and the award of attorneys fees and expenses. On April 7, 2021,
Charles Williams, a purported stockholder of the Company, commenced an action in the United States District Court for the District of Delaware, captioned Charles Williams v. Five Prime Therapeutics, Inc. et al., Case No. 1:21-cv-00508-UNA, against the Company and the current members of the Five Prime board of directors (the Williams
Complaint). The Williams Complaint asserts claims under Sections 14(d), 14(e), and 20(a) of the Exchange Act and seeks, among other things, an injunction preventing consummation of the proposed transaction with Amgen, rescission of the
proposed transaction or rescissory damages in the event it is consummated, filing of a corrected Schedule 14D-9, declaratory judgment, and the award of attorneys fees and expenses. The Company and the
current members of the Five Prime board of directors have been served with the Wang Complaint, the Dyson Complaint, the Wheeler Compliant, the Baker Complaint, and the Mills Complaint, but have not otherwise been served with the other complaints nor
have they answered any of the complaints. Neither Amgen nor Purchaser has been served with any of the complaints. Defendants believe the claims asserted in these complaints are without merit, deny any wrongdoing in connection with the filing of the
Schedule 14D-9, and intend to vigorously defend against the claims.