Pramlintide and Leptin Combination Treatment Demonstrates 12.7 Percent Weight Loss in 24-Week Clinical Obesity Study
November 15 2007 - 7:00AM
PR Newswire (US)
Findings validate novel integrated neurohormonal treatment of
obesity (INTO) strategy SAN DIEGO, Nov. 15 /PRNewswire-FirstCall/
-- Amylin Pharmaceuticals, Inc. (NASDAQ:AMLN) today announced
positive results from a 24-week proof-of-concept study with
pramlintide, an analog of human amylin, and recombinant human
leptin (r-metHuLeptin; metreleptin) combination treatment in
overweight or obese subjects. At study end, pramlintide/metreleptin
treatment reduced body weight on average by 12.7 percent,
significantly more than treatment with pramlintide alone (8.4
percent; p
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