Calm Cool + Corrected Eczema + Dermatitis Clinical Repair Balm to be Featured on “Get Ready, Gorgeous with Ali” on April 12 at 8 a.m. Eastern Time

NovaBay® Pharmaceuticals, Inc. (NYSE American: NBY), a company developing and commercializing high-quality, scientifically formulated eyecare and skincare products, announces that Chief Product Officer Audrey Kunin, MD will return to the QVC network as a live on-air guest to discuss DERMAdoctor’s problem-solving eczema treatment. The revolutionary Calm Cool + Corrected 1% Colloidal Oatmeal Eczema + Dermatitis Clinical Repair Balm will be featured on “Get Ready, Gorgeous with Ali” on Tuesday, April 12 at 8 a.m. Eastern time.

“After successfully introducing this proprietary, scientifically formulated and highly effective product to QVC viewers last month, it’s very exciting to be asked back to highlight the significant benefits of Calm Cool + Corrected 1% Colloidal Oatmeal Eczema + Dermatitis Clinical Repair Balm to QVC’s vast audience,” said Dr. Kunin. “Eczema is a significant concern for many, affecting an estimated 31 million Americans. Our Calm Cool + Corrected Eczema balm provides temporary relief of minor irritations and itching, while maximizing hydration to calm and soothe affected skin anywhere on the body.”

Dr. Kunin is a board-certified dermatologist, author, clinician, educator, television personality and recognized trailblazer in the skincare industry. She founded DERMAdoctor to provide simple, easy, at-home clinical skin therapy that delivers significant, measurable results for common skincare concerns that have been overlooked by the beauty industry.

Calm Cool + Corrected 1% Colloidal Oatmeal Eczema + Dermatitis Clinical Repair Balm is formulated with a special form of eczema-active 1% colloidal oatmeal with enhanced beta glucan, together with an advanced complex of ceramides and essential lipids and dermatologic botanicals. Calm Cool + Corrected 1% Colloidal Oatmeal Eczema + Dermatitis Clinical Repair Balm has received the National Eczema Association (NEA) Seal of Acceptance™, which is granted in recognition of products that meet the NEA’s rigorous standards for providing benefits and improving the quality of life for people with eczema and sensitive skin.

About NovaBay Pharmaceuticals, Inc:

NovaBay Pharmaceuticals, Inc. is a pharmaceutical company that develops and sells scientifically created and clinically proven consumer products for the eyecare and skincare markets. Avenova® is the most prescribed antimicrobial lid and lash spray in the eyecare market. In November 2021, NovaBay acquired DERMAdoctor, LLC, a company offering more than 30 dermatologist-developed skincare products sold through traditional domestic retailers, digital beauty channels and international distributors.

NovaBay Pharmaceuticals Forward-Looking Statements

Except for historical information herein, matters set forth in this press release may be forward looking within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995, including statements about the commercial progress and future financial performance of NovaBay Pharmaceuticals, Inc. This release contains forward-looking statements that are based upon management’s current expectations, assumptions, estimates, projections and beliefs. These statements include, but are not limited to, statements regarding our business strategies, current product offerings, marketing efforts, and any future revenue that may result from selling such products, as well as generally the Company’s expected future financial results. These statements involve known and unknown risks, uncertainties and other factors that may cause actual results or achievements to be materially different and adverse from those expressed in or implied by the forward-looking statements. Factors that might cause or contribute to such differences include, but are not limited to, risks and uncertainties relating to the size of the potential market for our products, the integration of DERMAdoctor’s business into the Company’s business, the possibility that the available market for the Company’s products will not be as large as expected, the Company’s products will not be able to penetrate one or more targeted markets, and revenues will not be sufficient to meet the Company’s cash needs. Other risks relating to NovaBay’s business, including risks that could cause results to differ materially from those projected in the forward-looking statements in this press release, are detailed in NovaBay’s latest Form 10-Q/K filings and Registration Statement on Form S-1 filing with the Securities and Exchange Commission, especially under the heading “Risk Factors.” The forward-looking statements in this release speak only as of this date, and NovaBay disclaims any intent or obligation to revise or update publicly any forward-looking statement except as required by law.

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Avenova Purchasing Information For NovaBay Avenova purchasing information: Please call 800-890-0329 or email sales@avenova.com Avenova.com

DERMAdoctor Purchasing Information For DERMAdoctor purchasing information: Please call 877-337-6237 or email service@dermadoctor.com DERMAdoctor.com

NovaBay Contact Justin Hall Chief Executive Officer and General Counsel 510-899-8800 jhall@novabay.com Investor Contact LHA Investor Relations Jody Cain 310-691-7100 jcain@lhai.com

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