As filed with the Securities and Exchange Commission on November 13, 2023

 

Registration No. 333-     

 

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

 

 

FORM S-8

 

REGISTRATION STATEMENT UNDER

THE SECURITIES ACT OF 1933

 

 

 

Lineage Cell Therapeutics, Inc.

(Exact name of Registrant as specified in its charter)

 

 

 

California

(State or other jurisdiction of

incorporation or organization)

 

94-3127919

(I.R.S. employer

identification number)

     

2173 Salk Avenue, Suite 200, Carlsbad, CA

(Address of principal executive offices)

 

92008

(Zip Code)

 

 

 

Lineage Cell Therapeutics, Inc. 2021 Equity Incentive Plan

(Full title of the plan)

 

George A. Samuel III

General Counsel and Secretary

Lineage Cell Therapeutics, Inc.

2173 Salk Avenue, Suite 200 Carlsbad, CA 92008

(Name and address of agent for service)

 

 

 

(442) 287-8990

(Telephone number, including area code, of agent for service)

 

 

 

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

 

Large accelerated filer Accelerated filer
       
Non-accelerated filer Smaller reporting company
       
    Emerging growth company

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

 

 

 

 
 

 

EXPLANATORY NOTE

 

This Registration Statement on Form S-8 is being filed by Lineage Cell Therapeutics, Inc. (“Lineage”), with the U.S. Securities and Exchange Commission (the “Commission”) for the purpose of registering an additional 19,500,000 common shares that may be issued under the Lineage 2021 Equity Incentive Plan (the “2021 Plan”). At Lineage’s annual meeting of shareholders held on September 6, 2023, Lineage’s shareholders approved an amendment to the 2021 Plan to increase the number of common shares reserved for issuance of awards made thereunder by a total of 19,500,000.

 

Lineage previously filed a Registration Statement on Form S-8 with the Commission on September 28, 2021 (File No. 333-259853) (the “Prior Registration Statement”) to register an aggregate of 30,358,599 common shares available for issuance under the 2021 Plan, consisting of, at a maximum, the sum of (i) 15,000,000 shares and (ii) an estimated 15,358,599 Prior Plan Returning Shares (as defined in the 2021 Plan). This Registration Statement registers an additional 19,500,000 common shares for issuance under the 2021 Plan, thereby increasing the total number of common shares available for issuance under the 2021 Plan to an amount not to exceed the sum of (i) 34,500,000 shares and (ii) the Prior Plan Returning Shares, if any, as such shares become available from time to time.

 

This Registration Statement relates to securities of the same class as those registered under the Prior Registration Statement and is being filed in accordance with General Instruction E to Form S-8. Pursuant to such instruction, the contents of the Prior Registration Statement related to the 2021 Plan are hereby incorporated by reference in and made part of this Registration Statement, except to the extent supplemented, superseded or modified by the specific information set forth below and/or the specific exhibits attached under Item 8 hereto, pursuant to Rule 412 under the Securities Act of 1933, as amended (the “Securities Act”).

 

In accordance with the instructional Note to Part I of Form S-8, the information specified by Part I of Form S-8 has been omitted from this Registration Statement for offers of common shares pursuant to the 2021 Plan. The documents containing the information specified in Part I will be delivered to the participants in the 2021 Plan as required by Rule 428(b)(1) under the Securities Act.

 

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PART II

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

 

Item 8. Exhibits

 

The following exhibits are filed as a part of or incorporated by reference into this Registration Statement:

 

        Incorporated by Reference    
Exhibit No.   Exhibit Description   Form   File No.   Exhibit   Filing Date   Filed Herewith
5.1 Opinion of Sheppard, Mullin, Richter & Hampton, LLP         X
23.1 Consent of WithumSmith+Brown, PC         X
23.2 Consent of Sheppard, Mullin, Richter & Hampton, LLP (included in Exhibit 5.1)         X
24.1 Power of Attorney (contained on the signature page of this Registration Statement)         X
99.1 Lineage Cell Therapeutics, Inc. 2021 Equity Incentive Plan 8-K 001-12830-211254211 10.1 09/15/2021  
99.2 Amendment to the Lineage Cell Therapeutics, Inc. 2021 Equity Incentive Plan 8-K 001-12830-231242967 10.1 09/06/2023  
99.3 Form of Stock Option Grant Notice and Agreement for Employees and Consultants under the Lineage Cell Therapeutics, Inc. 2021 Equity Incentive Plan 10-Q 001-12830-211396840 10.4 11/10/2021  
99.4 Form of Stock Option Grant Notice and Agreement for Non-Employee Directors under the Lineage Cell Therapeutics, Inc. 2021 Equity Incentive Plan 10-Q 001-12830-211396840 10.5 11/10/2021  
99.5 Form of Restricted Stock Unit Award Grant Notice and Agreement under the Lineage Cell Therapeutics, Inc. 2021 Equity Incentive Plan 10-Q 001-12830-211396840 10.6 11/10/2021  
107.1 Filing Fee Table         X

 

-3-
 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Carlsbad, State of California, on November 13, 2023.

 

  LINEAGE CELL THERAPEUTICS, INC.
     
By: /s/ Brian M Culley
Name: Brian M Culley
Title: Chief Executive Officer

 

KNOW ALL MEN BY THESE PRESENTS, that each of the undersigned officers and directors of Lineage Cell Therapeutics, Inc., constitutes and appoints Brian M. Culley and Jill Ann Howe, and each of them, his or her true and lawful attorney-in-fact and agent, with full power of substitution, for him or her and on his or her behalf and in his or her name, place and stead, in any and all capacities, to sign, execute and file this Registration Statement under the Securities Act of 1933, as amended, and any one or more amendments to any part of this Registration Statement, including any post- effective amendments, or appendices or supplements that may be required to be filed under the Securities Act of 1933, as amended, to keep such Registration Statement effective or to terminate its effectiveness, with all exhibits and any and all documents required to be filed with respect thereto, with the Securities and Exchange Commission or any regulatory authority, granting unto such attorney-in-fact and agent, full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises in order to effectuate the same, as fully to all intents and purposes as he or she himself or herself might or could do, if personally present, hereby ratifying and confirming all that said attorney-in-fact and agent, or his or her substitute or substitutes, may lawfully do or cause to be done.

 

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.

 

Signature   Title   Date
     
/s/ Brian M. Culley   Chief Executive Officer and Director   November 13, 2023
Brian M. Culley   (Principal Executive Officer)    
     
/s/ Jill Ann Howe   Chief Financial Officer   November 13, 2023
Jill Ann Howe   (Principal Financial and Accounting Officer)    
     
/s/ Alfred D. Kingsley   Chair of the Board   November 13, 2023
Alfred D. Kingsley        
     
/s/ Dipti Amin   Director   November 13, 2023
Dipti Amin        
     
/s/ Deborah Andrews   Director   November 13, 2023
Deborah Andrews        
         
/s/ Don M. Bailey   Director   November 13, 2023
Don M. Bailey        
     
/s/ Neal C. Bradsher   Director   November 13, 2023
Neal C. Bradsher        
         
/s/ Anula Jayasuriya   Director   November 13, 2023
Anula Jayasuriya        
     
/s/ Michael H. Mulroy   Director   November 13, 2023
Michael H. Mulroy        
     
/s/ Angus C. Russell   Director   November 13, 2023
Angus C. Russell        

 

-4-

 

Exhibit 5.1

 

Sheppard, Mullin, Richter & Hampton LLP

12275 El Camino Real, Suite 100

San Diego, CA 92130

www.sheppardmullin.com

 

November 13, 2023

 

VIA E-MAIL

Lineage Cell Therapeutics, Inc.

Attn: Board of Directors

2173 Salk Avenue, Suite 200

Carlsbad, CA 92008

 

Re: Registration Statement on Form S-8

 

Ladies and Gentlemen:

 

You have requested our opinion with respect to certain matters in connection with the filing by Lineage Cell Therapeutics, Inc., a California corporation (the “Company”), of a Registration Statement on Form S-8 (the “Registration Statement”) under the Securities Act of 1933, as amended (the “Securities Act”), with the Securities and Exchange Commission (the “SEC”), registering 19,500,000 common shares of the Company (the “Shares”) that may be issued from time to time under the Lineage Cell Therapeutics, Inc. 2021 Equity Incentive Plan (as amended to date, the “Plan”).

 

This opinion is being furnished in accordance with the requirements of Item 8 of Form S-8 and Item 601(b)(5)(i) of Regulation S-K.

 

In connection with this opinion, we have reviewed and relied upon the Registration Statement, the Company’s restated articles of incorporation, as amended and in effect as of the date hereof (the “Articles of Incorporation”), the Company’s amended and restated bylaws as in effect on the date hereof (the “Bylaws” and together with the Articles of Incorporation, the “Charter Documents”), the proceedings taken by the Company with respect to the authorization and adoption of the Plan, resolutions adopted by the board of directors of the Company, and such other documents, records, certificates, memoranda and other instruments as we deem necessary as a basis for this opinion. With respect to the foregoing documents, we have assumed (a) the genuineness of all signatures, (b) the authenticity of all documents submitted to us as originals and (c) the conformity to originals of all documents submitted to us as certified or reproduced copies. We have further assumed that (i) the common shares currently reserved for issuance under the Plan will remain available for the issuance of the Shares, and (ii) neither the Charter Documents nor any of the proceedings relating to either the Plan or any of the award agreements relating to the Shares will be rescinded, amended or otherwise modified prior to the issuance of the Shares. We have also obtained from public officials and officers of the Company certificates or comparable documents as to certain factual matters and, insofar as this opinion is based on matters of fact, we have relied on such certificates and comparable documents without independent investigation.

 

On the basis of the foregoing examination and in reliance thereon, subject to the further provisions hereof, we are of the opinion that if, as and when the Shares are issued and sold by the Company in accordance with the terms of the award agreements provided for under the Plan, and payment in full of the consideration therefor is received by the Company, the Shares will be validly issued, fully paid and nonassessable.

 

We consent to the filing of this opinion letter as an exhibit to the Registration Statement. In giving such consent, we do not thereby admit that we are included in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations of the SEC promulgated thereunder.

 

The foregoing opinion is limited to matters governed by the federal laws of the United States of America and the California General Corporation Law.

 

This opinion letter is rendered as of the date first written above solely for use in connection with the offer and sale of the Shares while the Registration Statement is in effect, and is not to be relied upon for any other purpose. We disclaim any obligation to advise you of facts, circumstances, events or developments which hereafter may be brought to our attention and which may alter, affect or modify the opinion expressed herein. Our opinion is expressly limited to the matters set forth above, and we render no opinion, whether by implication or otherwise, as to any other matters relating to the Company, the Shares, the Plan, the award agreements related to the Shares or the Registration Statement.

 

  Respectfully,
   
  /s/ Sheppard, Mullin, Richter & Hampton LLP
   
  SHEPPARD, MULLIN, RICHTER & HAMPTON LLP

 

 

 

Exhibit 23.1

 

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

 

We hereby consent to the incorporation by reference in this Registration Statement on Form S-8 of our report dated March 9, 2023, relating to the consolidated financial statements of Lineage Cell Therapeutics, Inc. appearing in the entity’s Annual Report on Form 10-K for the year ended December 31, 2022.

 

/s/ WithumSmith+Brown, PC

 

San Francisco, California

November 13, 2023

 

 

 

Exhibit 107.1

 

Calculation of Filing Fee Table

 

Form S-8

(Form Type)

 

Lineage Cell Therapeutics, Inc.

(Exact Name of Registrant as Specified in its Charter)

 

Table 1: Newly Registered Securities

 

Security type  Security
class
title
  Fee
calculation
rule
  Amount
registered (1)
   Proposed
maximum
offering
price per
unit (2)
   Maximum
aggregate
offering
price
   Fee
rate
   Amount of
registration
fee
 
Equity  Common Shares  Other   19,500,000   $1.06(3)  $20,670,000.00    0.0001476   $3,050.89 
Total Offering Amounts  $20,670,000.00        $3,050.89 
Total Fee Offsets              
Net Fee Due            $3,050.89 

 

(1)Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such number of additional common shares that may become issuable under the Lineage Cell Therapeutics, Inc. 2021 Equity Incentive Plan by reason of any stock split, stock dividend, recapitalization, or any other similar transaction effected that results in an increase to the number of outstanding common shares of the registrant.
  
(2)Estimated solely for the purpose of computing the registration fee in accordance with Rules 457(c) and 457(h) under the Securities Act of 1933.
  
(3)The proposed maximum offering price is based on the average of the high and the low prices per common share of the registrant as reported on the NYSE American as of a date (November 10, 2023) within five business days prior to the filing of this Registration Statement.

 

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