TIDMTED 
 
FORM 8.3 
 
   DEALINGS BY PERSONS WITH INTERESTS IN SECURITIES REPRESENTING 1% OR MORE 
 
                        (Rule 8.3 of the Takeover Code) 
 
1. KEY INFORMATION 
 
Name of person dealing (Note 1) OrbiMed Capital LLC 
 
Company dealt in                Tepnel Life Sciences Plc 
 
Class of relevant security to   1p ordinary 
which the dealings being 
disclosed relate (Note 2) 
 
Date of dealing                 April 3. 2009 
 
2. INTERESTS, SHORT POSITIONS AND RIGHTS TO SUBSCRIBE 
 
(a) Interests and short positions (following dealing) in the class of relevant 
security dealt in (Note 3) 
 
                                         Long                   Short 
 
                                Number (%)             Number (%) 
 
(1) Relevant securities         92,840,000 28.04% 
 
(2) Derivatives (other than 
options) 
 
(3) Options and agreements to 
purchase/sell 
 
Total 
 
(b) Interests and short positions in relevant securities of the company, other 
than the class dealt in (Note 3) 
 
Class of relevant security:              Long                   Short 
 
                                Number (%)             Number (%) 
 
(1) Relevant securities 
 
(2) Derivatives (other than 
options) 
 
(3) Options and agreements to 
purchase/sell 
 
Total 
 
(c) Rights to subscribe (Note 3) 
 
Class of relevant security:     Details 
 
 
3. DEALINGS (Note 4) 
 
(a) Purchases and sales 
 
Purchase/sale              Number of securities      Price per unit (Note 5) 
 
 
(b) Derivatives transactions (other than options) 
 
Product name,  Long/short (Note  Number of securities     Price per unit (Note 
               6)                (Note 7)                 5) 
e.g. CFD 
 
 
(c) Options transactions in respect of existing securities 
 
(i) Writing, selling, purchasing or varying 
 
Product name, Writing,    Number of     Exercise Type, e.g. Expiry  Option 
              selling,    securities to          American,          money 
e.g. call     purchasing, which the     price    European   date 
option        varying     option                 etc.               paid/ 
              etc.        relates (Note                             received 
                          7)                                        per unit 
                                                                    (Note 5) 
 
 
(ii) Exercising 
 
Product name, e.g. call    Number of securities      Exercise price per unit 
option                                               (Note 5) 
 
 
(d) Other dealings (including new securities) (Note 4) 
 
Nature of transaction      Details                   Price per unit (if 
(Note 8)                                             applicable) (Note 5) 
 
Exercise of warrants       Received 45,840,000       Exercise price of 6.98 
                           ordinary shares           pence per share 
 
4. OTHER INFORMATION 
 
Agreements, arrangements or understandings relating to options or derivatives 
 
Full details of any agreement, arrangement or understanding between the person 
disclosing and any other person relating to the voting rights of any relevant 
securities under any option referred to on this form or relating to the voting 
rights or future acquisition or disposal of any relevant securities to which 
any derivative referred to on this form is referenced. If none, this should be 
stated. 
 
OrbiMed Capital LLC holds investment and voting discretion over the following 
entities: 
 
Finsbury Worldwide Pharmaceutical Trust plc 74,000,000 ordinary shares (22.35%) 
 
The Biotech Growth Trust plc 18,840,000 ordinary shares (5.69%) 
 
 
Is a Supplemental Form 8 attached? (Note 9)  NO 
 
Date of disclosure                           April 6, 2009 
 
Contact name                                 Eric Bittelman 
 
Telephone number                             212-739-6400 
 
If a connected EFM, name of offeree/offeror  N/A 
with which connected 
 
If a connected EFM, state nature of          N/A 
connection (Note 10) 
 
Notes 
 
The Notes on Form 8.3 can be viewed on the Takeover Panel's website at 
www.thetakeoverpanel.org.uk 
 
 
 
END 
 

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