TIDMINS

RNS Number : 5728M

Instem plc

19 September 2012

19 September 2012

Embargoed for 07:00

Instem plc

("Instem", the "Company" or the "Group")

Unaudited Interim Results

Instem plc (AIM: INS.L), a leading provider of IT applications to the global early development healthcare market, announces its unaudited interim results for the six months ended 30 June 2012.

Financial Highlights

-- Revenues steady at GBP4.9m (H1 2011: GBP4.9m)

o Recurring revenues accounted for 74% of total (H1 2011: 70%)

o Software-as-a-Service (SaaS) revenue up 21% to GBP0.6m (2011: GBP0.5m)

-- Operating profit before amortisation, share based payment and non-recurring items GBP0.3m (H1 2011: GBP0.6m)

-- Basic earnings per share (0.1)p (H1 2011: 1.1p)

-- Seasonal operating cash outflow of GBP1.2m (H1 2011: GBP1.4m)

-- Closing cash balance as at 30 June 2012 of GBP1.8m (H1 2011: GBP1.3m)

Operational Highlights

-- New contracts include a leading pharma in Japan, Advinus Therapeutics and Lupin Limited in India, and licence extensions with several Contract Research Organisations in the US and Europe

-- Customer retention rate remained strong at over 95%

-- Released Provantis(R) version 9 in July 2012, the final major release in a multi-year migration of the Provantis suite to the latest technology platform

-- Strong pipeline of customer opportunities for both Provantis(R) (pre- and non-clinical studies) and Centrus(TM) (data access and harmonization)

Phil Reason, CEO of Instem plc, commented:

"Instem has started the second half of the year in line with management expectations, as reflected in the Company's trading update issued 26 July 2012, and we are confident of being strongly cash positive in the second half.

"The breadth of the Company's Provantis and Centrus suites, combined with its extensive geographical reach, blended SaaS and traditional licence model continue to be key competitive differentiators. Instem is currently working on multiple contract opportunities, from both new and existing customers. These are predominantly in the US market, but also within the European market which is starting to show initial signs of recovery following a difficult 2011 in which several large European research facilities were closed.

"Overall, while the Board remains cautious regarding the timing of deal flow, it is optimistic about the medium to long-term prospects for the business which remains well positioned to benefit from the trends in its end markets towards multi-site, collaborative and outsourced R&D."

For further information, please contact:

 
Instem plc                        +44 (0) 1785 825 600 
Phil Reason, CEO 
Nigel Goldsmith, CFO 
 
N+1 Brewin (Nominated Adviser & 
 Broker)                          +44 (0) 20 3201 3710 
Aubrey Powell 
Luke Boyce 
 
Newgate Threadneedle              +44 (0) 20 7653 9850 
Caroline Evans-Jones 
Fiona Conroy 
 

About Instem plc

Instem is a leading supplier of IT solutions to the early development healthcare market. Instem's pre-clinical study management solutions accelerate drug and chemical development by increasing productivity, automating processes and enhancing practices that lead to safer and more effective drugs.

Instem has over 130 customers in North America, Europe, China, India and Japan, including 16 of the top 20 pharmaceutical and biotech companies such as GlaxoSmithKline and AstraZeneca. The Group employs over 110 people in seven offices in the US, UK, China and India; and has a full service distributor in Japan. It is estimated that approximately half of the world's pre-clinical drug safety data has been collected over the last 20 years via Instem software, making Instem an ideal partner to help unlock the scientific/commercial value from these legacy repositories.

To learn more about Instem please visit the Company's website, www.instem.com, or its investor centre http://investors.instem.com/.

Chairman's Statement

While the results are lower than management's original expectations for the half, we believe that this performance has been in line with the broader pharmaceutical market. Large pharma in particular continues to go through a period of major structural change. The uncertainty this creates means that clients and prospects have tended to defer investment decisions. Nonetheless, we believe we have continued to win the majority of business placed in our market and the Board is confident that underlying demand for Instem's solutions remains strong.

Several large, multi-site prospects are in the pipeline and, in several instances, selection decisions have already been made in Instem's favour by prospective customers; but order dates and final contract size remain subject to additional procurement processes.

The Group's substantial recurring revenue base continues to grow, now having reached approximately GBP7.4m on an annualised basis, providing a solid, profitable and cash-generative platform for the business. Renewal rates have remained high, at over 95%.

The Board believes its core Provantis and Centrus solutions are ultimately well placed to benefit from the changes to laboratory working practices, such as the growing prominence of multi-site working and outsourcing, as well as the adoption of new standards. Significant customer benefits, enhanced revenue opportunities and reduced costs resulting from the completion of the last major phase of the redevelopment of the core Provantis(R) product suite during 2012 are expected to contribute positively to future business performance.

Overall, while the Board remains cautious regarding the timing of contract flow, it is confident in the medium to long-term prospects for Instem, which remains well positioned to benefit from the strategic trends in its end markets towards multi-site, collaborative and outsourced R&D.

David Gare

Chairman

19 September 2012

Operational Review

Although results for the period were impacted by the continued uncertainty and budgetary restraints that are on-going within the Pharmaceutical market, Instem has continued to make good progress at an operational level, securing new customers, extending licences within existing customers and maintaining high renewal rates. We have already delivered a significantly enhanced release of Provantis in the second half of the year.

Customer update

We are confident that Instem continues to outperform its competitors in product evaluations. Instem's ability to provide support for all geographic areas and offer our software via either the SaaS or traditional licence model means we are well placed to tender for current opportunities globally.

Two Indian contracts

The Group's Indian operations were successfully launched in the first half of the year, providing Instem with the ability and flexibility to scale-up development resources in the region in response to demand. This local presence will also be beneficial as we implement two contracts secured in the first half of 2012: Advinus Therapeutics, an existing customer, is upgrading and further extending its use of Provantis, and Lupin Limited selected Provantis to automate study processes at its Global R&D hub in Pune.

Japanese customer win

Instem extended its presence in Japan, securing a contract with one of Japan's leading research-oriented global pharmaceutical companies, which purchased the Provantis preclinical software solution for its Osaka R&D facility, following a competitive evaluation. A comprehensive suite of modules was purchased to support the areas of General Toxicology, Reproductive Toxicology, Pathology and Pharmacy.

Customer extensions at CROs

Several of Instem's smaller US and European Contract Research Organisation (CRO) customers added Provantis user and module licences during the period. This is a good indicator that the smaller end of the market may be seeing a sustainable return to growth.

Instem Scientific

Instem Scientific, our team focused on information solutions for translational science, enjoyed a high rate of recurring revenue renewal across all product lines reflecting the strong long-term partnerships with its life science customers. Post period end, Instem Scientific added another blue-chip client, DuPont, who became the latest customer of our large scale data integration platform SRS(TM).

Instem Scientific's solutions are now being purchased in conjunction with our other products and we successfully completed the first integrated project with Instem's Study Management solutions in the period, through the delivery of the new Provantis Portal module to The Jackson Laboratory.

Instem Scientific and Apelon, the international informatics company, extended their partnership to deploy advanced technology for patient-focused clinical decision support. The two businesses have worked together in previous partnerships, combining Instem's suite of taxonomic and semantic products and services with Apelon's vocabulary creation expertise to deliver unique solutions for pharmaceutical R&D and the wider healthcare IT market.

This blend of Instem technology and Apelon's scientific management services will enhance the effectiveness of drug prescribing by healthcare clinicians, improve patient outcomes and lower the costs of care. Pharmaceutical organisations will also benefit from the availability of data which was previously inaccessible.

Increasing competitive strength of the product set

Instem continued to add to the competitive differentiation of the Provantis suite during the first half of the year. One such new development was the release of Provantis Portal, a web portal predominantly for CROs to deliver Provantis managed study data to their clients in a secure manner. In addition, a partnership was secured with Trimetra for its Logbook software; Logbook is an Electronic Notebook and Data Collection system that can replace GLP (Good Laboratory Practice) and Non-GLP paper forms. This partnership will enable Instem's customers to replace the final extraneous paper forms that may exist in the laboratory environment, which to date have not had a natural filing location within Provantis. We are not aware of a similar product on the market and have seen a good level of interest from customers and prospective customers alike.

Instem successfully delivered Provantis 9, a major new release of its core Provantis product suite, in July 2012. The release largely completes a significant, phased multi-year product redevelopment, which supports the changes to laboratory working practices brought about by the structural changes in the pharma market and takes advantage of the latest capabilities of the underlying Microsoft(R) and Oracle(R) platform technologies. Unique Provantis capabilities that improve operational efficiency and reduce study timelines are proving key competitive differentiators.

Instem's much newer Centrus product suite is building good momentum, particularly the modules associated with the recently adopted US Food & Drug Administration sponsored Standard for the Exchange of Non-clinical Data (SEND). As pharma companies face increased regulatory scrutiny and deal with expensive drug safety litigation, there are signs that investments to achieve regulatory compliance are being prioritized, The Group's leading position in this developing area was underlined in February 2012, when Instem was recognised for its outstanding contributions to SEND at the Interchange North America event organised by CDISC, the Clinical Data Interchange Standards Consortium.

Opportunities remain to extend Instem's product and services offerings and to leverage its well established global sales, marketing and service delivery infrastructure, particularly our Software-as-a-Service platform. As clients plan their upgrades to Provantis 9, they frequently take the opportunity to consider the purchase of additional products and modules that they have not previously licensed.

Financial Review

The financial results demonstrate a solid performance in the period with total revenues steady year-on-year at GBP4.9m (H1 2011: GBP4.9m). Whilst implementation service revenues in the first half of the year benefited from a solid order book brought forward from 2011, the business as a whole has experienced slippage in expected new orders with customers deferring investment decisions on some major projects. The Group generates the majority of its revenue in US dollars, which are hedged into sterling.

The business continued to expand in developing markets with revenue from outside North America and Europe increasing to GBP0.6m (H1 2011: GBP0.4m), representing 12% of total revenue (H1 2011: 9%).

Instem's business model consists of fees for perpetual licences, annual support, SaaS subscriptions and professional services. In the period, approximately 74% (H1 2011: 70%) of revenue was of a recurring nature from annual support fees and SaaS subscriptions.

Profit from operations before amortisation, share-based payment and non-recurring costs for the period, was GBP0.3m (H1 2011: GBP0.6m). Operating expenses increased by GBP0.25m in the half year over the equivalent period in 2011 due to inflation and there being a full six months of Instem Scientific costs compared with four months from the date of acquisition in 2011. Amortisation increased by GBP0.1m over the equivalent period in 2011 reflecting the increased investment in intangibles including those assets acquired through the purchase of Instem Scientific.

Development costs incurred in the period were GBP0.9m (H1 2011: GBP0.9m), of which GBP0.1m were capitalised (H1 2011: GBP0.1m).

Non-recurring items include a charge of GBP0.11m in respect of legal and professional fees associated with pursuing acquisition opportunities, offset by a GBP0.14m write-back of provision for deferred contingent consideration in respect of Instem Scientific.

In common with many businesses with a defined benefit pension scheme, there was an increase in the funding deficit during the period calculated in accordance with the provisions of IAS19 that amounted to GBP1.4m (net of deferred tax), which has been recognised in Other Comprehensive Income/(Expense). This was a non-cash charge in the period and arose as a result of lower discount rates used for calculation of the liabilities and lower expected returns on assets. As part of the scheme's triennial actuarial valuation as at 5 April 2011, the Company has agreed a schedule of payments to the scheme with the trustees and the Pensions Regulator that is designed to eliminate the funding deficit over an eight year period. This involves a modest increase of GBP0.09m in the Company's payments to the scheme, rising from GBP0.3m to GBP0.4m per annum from January 2013. The defined benefit pension scheme has remained closed to new members since 2000 and to future accrual since 2008.

Instem's cash flow is seasonal, with cash inflow being weighted to the second half of the year resulting from the number of annual fee renewals occurring at the year end. As a result of the normal working capital cycle, assisted by sales receipts in the first quarter from the orders received late in 2011, cash at the end of June 2012 was GBP1.8m (H1 2011: GBP1.3m) compared with GBP3.4m at December 2011. A scheduled debt repayment of GBP0.25m was made in the period together with a payment of GBP0.08m as contingent consideration relating to the performance of Instem Scientific in 2011.

In line with previous periods, and our current policy of retaining cash within the business to capitalise on the available growth opportunities, the Board has not recommended the payment of a dividend.

Principal risks and uncertainties

The principal risks and uncertainties remain unchanged from those described in our 2011 Annual Report.

Outlook

Instem has started the second half of the year in line with management's expectations, as reflected in the Company's trading update issued on 26 July 2012. The tentative signs of recovery in our global markets have been sustained and, although the Board continues to be cautious about the timing of contract flow, our pipeline remains healthy. Instem has seen growing evidence of demand for its products internationally, notwithstanding the ongoing customer delays to implementation of investment decisions.

Due to the significant levels of recurring revenue and the profile of our annual licencerenewals, we are confident that the business will be strongly cash positive in the second half which will provide sufficient flexibility to support the growth of the business both through organic investment and selective acquisition opportunities.

The breadth of the Company's Provantis and Centrus suites continues to be a key competitive differentiator as does Instem's ability to offer a blended SaaS and traditional licence model. Instem is committed to continued product innovation and is confident of its leading position within the early development market, which is further bolstered by its extensive geographical reach. The Company therefore remains well positioned to benefit from the trends in its end markets towards multi-site, collaborative and outsourced R&D and the Board is confident in the future for Instem.

Phil Reason

Chief Executive

19 September 2012

CONSOLIDATED STATEMENT OF COMPREHENSIVE INCOME

For the six months ended 30 June 2012

 
                                                                  Unaudited          Unaudited                 Audited 
                                                           Six months ended   Six months ended                    Year 
                                                                    30 June            30 June       ended 31 December 
                                                                       2012               2011                    2011 
                                                                     GBP000             GBP000                  GBP000 
                                                   Note 
 
 REVENUE                                                              4,869              4,893                  10,793 
 Operating expenses                                                 (4,560)            (4,306)                 (8,791) 
                                                         ------------------  -----------------  ---------------------- 
 PROFIT FROM OPERATIONS BEFORE AMORTISATION, 
  SHARE BASED PAYMENT AND NON RECURRING 
  INCOME/(COSTS)                                                        309                587                   2,002 
 
 Amortisation of intangibles                                          (245)              (154)                   (347) 
 Share based payment                                                   (54)               (53)                    (88) 
                                                         ------------------  -----------------  ---------------------- 
 PROFIT BEFORE NON RECURRING INCOME/(COSTS)                              10                380                   1,567 
 
   Non-recurring income/(costs)                       4                  27              (106)                    (21) 
                                                         ------------------  -----------------  ---------------------- 
 PROFIT FROM OPERATIONS                                                  37                274                   1,546 
 
 Finance income                                                         286                265                     422 
 Finance costs                                                        (214)              (245)                   (456) 
                                                         ------------------  -----------------  ---------------------- 
 PROFIT BEFORE TAXATION                                                 109                294                   1,512 
 
   Income tax expense                                 5               (125)              (170)                   (506) 
                                                         ------------------  -----------------  ---------------------- 
 (LOSS)/PROFIT FOR THE PERIOD/YEAR                                     (16)                124                   1,006 
                                                         ------------------  -----------------  ---------------------- 
 
 OTHER COMPREHENSIVE INCOME/(EXPENSE) 
 Actuarial loss on retirement benefit 
  obligations                                                       (1,781)               (27)                   (392) 
 Deferred tax on actuarial loss                                         428                  7                      68 
 Exchange differences on translating foreign 
  operations                                                          (113)                 39                      96 
                                                         ------------------  -----------------  ---------------------- 
 OTHER COMPREHENSIVE (EXPENSE)/INCOME FOR THE 
  PERIOD/YEAR                                                       (1,466)                 19                   (228) 
                                                         ------------------  -----------------  ---------------------- 
 
   TOTAL COMPREHENSIVE (EXPENSE)/INCOME FOR 
   THE PERIOD/YEAR                                                  (1,482)                143                     778 
                                                         ==================  =================  ====================== 
 
   (LOSS)/PROFIT ATTRIBUTABLE TO EQUITY 
   HOLDERS OF THE PARENT COMPANY                                       (16)                124                   1,006 
                                                         ==================  =================  ====================== 
 
   TOTAL COMPREHENSIVE (EXPENSE)/INCOME 
   ATTRIBUTABLE TO EQUITY HOLDERS OF THE 
   PARENT COMPANY                                                   (1,482)                143                     778 
                                                         ==================  =================  ====================== 
 
 Earnings per Share from continuing operations 
  - Basic                                             3              (0.1)p               1.1p                    8.6p 
                                      - 
                                       Diluted        3          (0.1)p                   1.1p                    8.5p 
 

CONSOLIDATED STATEMENT OF FINANCIAL POSITION

As at 30 June 2012

 
                                           Unaudited   Unaudited       Audited 
                                                  30          30   31 December 
                                                June        June          2011 
                                    Note        2012        2011 
                                              GBP000      GBP000        GBP000 
 ASSETS 
 NON-CURRENT ASSETS 
 Intangible assets                             7,993       8,122         8,103 
 Property, plant and equipment                   230         142           188 
 Deferred tax assets                             636         322           279 
                                          ----------  ----------  ------------ 
 TOTAL NON-CURRENT ASSETS                      8,859       8,586         8,570 
 
 CURRENT ASSETS 
 Inventories                                     163         166            93 
 Trade and other receivables                   2,238       2,275         3,029 
 Current tax assets                              170         180            64 
 Cash and cash equivalents                     1,848       1,332         3,368 
                                          ----------  ----------  ------------ 
 TOTAL CURRENT ASSETS                          4,419       3,953         6,554 
 
 TOTAL ASSETS                                 13,278      12,539        15,124 
                                          ==========  ==========  ============ 
 
 LIABILITIES 
 CURRENT LIABILITIES 
 Trade and other payables                      5,636       5,253         7,594 
 Derivative financial instrument                  25           -             - 
 Current tax liabilities                         123           -             - 
 Financial liabilities                           250       1,020           250 
                                          ----------  ----------  ------------ 
 TOTAL CURRENT LIABILITIES                     6,034       6,273         7,844 
 
 NON-CURRENT LIABILITIES 
 Financial liabilities                             -         241           250 
 Retirement benefit obligations        6       3,172       1,281         1,616 
                                          ----------  ----------  ------------ 
 TOTAL NON-CURRENT LIABILITIES                 3,172       1,522         1,866 
 
 TOTAL LIABILITIES                             9,206       7,795         9,710 
                                          ----------  ----------  ------------ 
 
 EQUITY 
 Share capital                                 1,177       1,171         1,171 
 Share premium                                 7,893       7,813         7,813 
 Merger reserve                                (932)       (932)         (932) 
 Shares to be issued                             142          53            88 
 Translation reserve                             360         416           473 
 Retained earnings                           (4,568)     (3,777)       (3,199) 
                                          ----------  ----------  ------------ 
 
 TOTAL EQUITY ATTRIBUTABLE TO 
  EQUITY HOLDERS OF THE PARENT                 4,072       4,744         5,414 
 
 TOTAL EQUITY AND LIABILITIES                 13,278      12,539        15,124 
                                          ==========  ==========  ============ 
 

CONSOLIDATED STATEMENT OF CASH FLOWS

For the six months ended 30 June 2012

 
                                                                Unaudited          Unaudited                   Audited 
                                                         Six months ended   Six months ended                      Year 
                                                                  30 June            30 June    ended 31 December 2011 
                                                                     2012               2011                    GBP000 
                                                                   GBP000             GBP000 
 CASH FLOWS FROM OPERATING ACTIVITIES 
 Result before taxation                                               109                294                     1,512 
 
 Adjustments for: 
 Depreciation                                                          28                 36                       116 
 Amortisation of intangibles                                          245                154                       347 
 Profit on disposal of property, plant and equipment                    -                  -                      (14) 
 Adjustment to consideration                                        (141)                  -                      (80) 
 Share based payments and shares to be issued                          54                 53                        88 
 Retirement benefit obligations                                     (265)              (251)                     (245) 
 Net foreign exchange gains                                             -                  -                        88 
 Finance income                                                     (286)              (265)                     (422) 
 Finance costs                                                        214                245                       456 
 Forward contract valuation movement                                   25                 12                         - 
                                                       ------------------  -----------------  ------------------------ 
 
   CASH FLOWS FROM OPERATIONS BEFORE MOVEMENTS IN 
   WORKING CAPITAL                                                   (17)                278                     1,846 
 
 Changes in working capital: 
 (Increase)/decrease in inventories                                  (70)               (29)                        47 
 Decrease/(increase) in trade and other receivables                   573              (549)                   (1,230) 
 (Decrease)/increase in trade and other payables                  (1,639)            (1,082)                       679 
                                                       ------------------  -----------------  ------------------------ 
 
   CASH (USED IN)/GENERATED FROM OPERATIONS                       (1,153)            (1,382)                     1,342 
 
 Finance costs                                                      (174)              (211)                     (362) 
 Income tax paid                                                     (37)              (207)                     (478) 
                                                       ------------------  -----------------  ------------------------ 
 
   NET CASH (USED IN)/GENERATED FROM OPERATING 
   ACTIVITIES                                                     (1,364)            (1,800)                       502 
 
 CASH FLOWS FROM INVESTING ACTIVITIES 
 Finance income received                                              286                265                       300 
 Income tax paid                                                        -              (153)                         - 
 Purchase of intangible assets                                       (25)              (117)                     (291) 
 Purchase of property, plant and equipment                           (70)               (11)                     (152) 
 Acquisition - cash consideration                                    (82)                  -                         - 
 Disposal of property, plant and equipment                              -                  -                        30 
 Acquisition of subsidiary                                              -              (200)                     (200) 
 Cash acquired with subsidiary                                          -                141                       141 
                                                       ------------------  -----------------  ------------------------ 
 
   NET CASH GENERATED BY/(USED IN) INVESTING 
   ACTIVITIES                                                         109               (75)                     (172) 
 
 CASH FLOWS FROM FINANCING ACTIVITIES 
 Series "A" Loan notes repaid                                           -               (44)                     (253) 
 Loan repayments                                                    (250)                  -                         - 
 Payment of finance lease liabilities                                   -                (3)                         - 
                                                       ------------------  -----------------  ------------------------ 
 
   NET CASH USED IN FINANCING ACTIVITIES                            (250)               (47)                     (253) 
                                                       ------------------  -----------------  ------------------------ 
 
 NET (DECREASE)/INCREASE IN CASH AND CASH EQUIVALENTS             (1,505)            (1,922)                        77 
 Cash and cash equivalents at start of year                         3,368              3,263                     3,263 
 Effect of exchange rate changes on the balance of 
  cash held in foreign currencies                                    (15)                (9)                        28 
                                                       ------------------  -----------------  ------------------------ 
 
   CASH AND CASH EQUIVALENTS AT END OF PERIOD/YEAR                  1,848              1,332                     3,368 
                                                       ==================  =================  ======================== 
 

CONSOLIDATED STATEMENT OF CHANGES IN EQUITY

For the six months ended 30 June 2012

 
                         Called up   Share premium     Merger    Shares to be   Translation         Retained     Total 
                     share capital                    reserve          issued       reserve         earnings    Equity 
                            GBP000          GBP000     GBP000          GBP000        GBP000           GBP000    GBP000 
 
 Balance as at 1 
  January 2011               1,171           7,813      (932)               -           377          (3,881)     4,548 
 
 Profit for the 
  period                         -               -          -               -             -              124       124 
 Other 
  comprehensive 
  income/(expense)               -               -          -               -            39             (20)        19 
 Share based 
  payment                        -               -          -              53             -                -        53 
                    --------------  --------------  ---------  --------------  ------------  ---------------  -------- 
 
   Balance as at 
   30 June 2011              1,171           7,813      (932)              53           416          (3,777)     4,744 
 
 Profit for the 
  period                         -               -          -               -             -              882       882 
 Other 
  comprehensive 
  income/(expense)               -               -          -               -            57            (304)     (247) 
 Share based 
  payment                        -               -          -              35             -                -        35 
                    --------------  --------------  ---------  --------------  ------------  ---------------  -------- 
 
   Balance as at 
   31 December 
   2011                      1,171           7,813      (932)              88           473          (3,199)     5,414 
 
 Transactions with 
  owners in their 
  capacity as 
  owners:- 
  Share issue                    6              80          -               -             -                -        86 
                    --------------  --------------  ---------  --------------  ------------  ---------------  -------- 
 
                                 6              80          -               -             -                -        86 
 Loss for the 
  period                         -               -          -               -             -             (16)      (16) 
 Other 
  comprehensive 
  expense                        -               -          -               -         (113)          (1,353)   (1,466) 
 Share based 
  payment                        -               -          -              54             -                -        54 
                    --------------  --------------  ---------  --------------  ------------  ---------------  -------- 
 
   Balance as at 
   30 June 2012              1,177           7,893      (932)             142           360          (4,568)     4,072 
                    ==============  ==============  =========  ==============  ============  ===============  ======== 
 

NOTES TO THE FINANCIAL INFORMATION

For the six months ended 30 June 2012

GENERAL INFORMATION

The principal activity of Instem plc and subsidiaries is the provision of world class information solutions for life sciences research and development.

Notes to the accounts

   1.         Basis of preparation and accounting policies 

Basis of preparation

The Group's half-yearly financial information, which is unaudited, consolidates the results of Instem plc and its subsidiary undertakings made up to 30 June 2012. The Group's accounting reference date is 31 December.

The company is a public limited liability company incorporated and domiciled in England & Wales. The consolidated financial information is presented in Pounds Sterling (GBP) which is also the functional currency of the parent.

The financial information contained in this half-yearly financial report does not constitute statutory accounts as defined in section 434 of the Companies Act 2006. It does not therefore include all of the information and disclosures required in the annual financial statements.

The financial information for the six months ended 30 June 2011 is also unaudited.

Instem plc's consolidated statutory accounts for the year ended 31 December 2011, prepared under IFRS, have been delivered to the Registrar of Companies. The report of the auditors on these accounts was unqualified and did not contain a statement under Section 498 (2) or (3) of the Companies Act 2006.

Significant accounting policies

The accounting policies used in the preparation of the financial information for the six months ended 30 June 2012 are in accordance with the recognition and measurement criteria of International Financial Reporting Standards ('IFRS') as adopted by the European Union and are consistent with those which will be adopted in the annual statutory financial statements for the year ending 31 December 2012.

While the financial information included has been prepared in accordance with the recognition and measurement criteria of International Financial Reporting Standards (IFRS), as adopted by the European Union (EU), these financial statements do not contain sufficient information to comply with IFRSs.

Instem plc has not applied IAS 34, Interim Financial Reporting, which is not mandatory for UK AIM listed groups, in the preparation of this half-yearly financial report.

Cash and cash equivalents

Cash and cash equivalents for the purposes of the Statement of Cash Flows comprise the net of cash and overdraft balances that are shown on the Statement of Financial Position in Cash and Cash Equivalents and Current Financial Liabilities.

   2.         Segmental Information 

The Directors consider that the Group operates in one business segment, being IT applications to the global healthcare market, and that therefore there are no additional segmental disclosures to be made in this financial information.

   3.         Earnings per Share 

(a) Basic

 
                                     Six months 
                                          ended        Six months     Year ended 
                                        30 June             ended    31 December 
                                           2012           30 June           2011 
                                      Unaudited    2011 Unaudited        Audited 
 
 (Loss)/Profit after tax (GBP000)          (16)               124          1,006 
                                    -----------  ----------------  ------------- 
 
 Weighted average number of 
  shares ('000s)                         11,745            11,714         11,714 
                                    -----------  ----------------  ------------- 
 
 Basic earnings per share (p 
  per share)                              (0.1)               1.1            8.6 
                                    ===========  ================  ============= 
 
           (b)   Diluted 
 
                                     Six months 
                                          ended        Six months     Year ended 
                                        30 June             ended    31 December 
                                           2012           30 June           2011 
                                      Unaudited    2011 Unaudited        Audited 
 
 (Loss)/Profit after tax (GBP000)          (16)               124          1,006 
                                    -----------  ----------------  ------------- 
 
 Weighted average number of 
  shares ('000s)                         11,745            11,714         11,714 
 
 Adjustments for share options 
  ('000s)                                     -                 7            134 
 
 Adjusted weighted average 
  number of shares ('000s)               11,745            11,721         11,848 
                                    -----------  ----------------  ------------- 
 
 Diluted earnings per share 
  (p per share)                           (0.1)               1.1            8.5 
                                    ===========  ================  ============= 
 
   4.         Non recurring income/(costs) 

Non recurring costs of GBP0.11m represent professional fees and other costs incurred in relation to the identification and assessment of acquisition targets (2011: acquisition of Instem Scientific GBP0.11m).

These costs have been offset by the release of GBP0.14m surplus provision for deferred consideration in respect of Instem Scientific.

   5.         Taxation on ordinary activities 
 
                       Six months 
                            ended        Six months     Year ended 
                          30 June             ended    31 December 
                             2012           30 June           2011 
                        Unaudited    2011 Unaudited        Audited 
                           GBP000            GBP000         GBP000 
 Current tax: 
 Corporation tax                -                83            167 
 Foreign tax                   55                68            162 
                      -----------  ----------------  ------------- 
 Total current tax             55               151            329 
                      -----------  ----------------  ------------- 
 
 Deferred tax: 
                      -----------  ----------------  ------------- 
 Total deferred tax            70                19            177 
                      -----------  ----------------  ------------- 
 
 Income tax expense           125               170            506 
                      ===========  ================  ============= 
 
   6.         Retirement benefit obligations 

The latest full triennial actuarial valuation of the defined benefit scheme, the Instem LSS Pension Scheme, was carried out as at 5 April 2011 and was finalised on 5 July 2012. The Scheme data was used by a qualified independent actuary to determine the valuation for accounts purposes as at 30 June 2012 in accordance with the provisions of IAS19. The 2011 comparative numbers were based on the prior triennial actuarial valuation at 5 April 2008 updated at 30 June 2011 and at 31 December 2011. The value of assets held by the Scheme was calculated by reference to monthly statements from the Scheme asset management company. The liabilities at 30 June 2012 were calculated by the actuary on a basis consistent with the valuations carried out at 30 June 2011 and 31 December 2011.

The expected return on plan assets was determined by considering the expected returns available on the assets underlying the current investment portfolio. Expected yields on bonds are based on gross redemption yields at the reporting date whilst the expected returns on the equity and property investments reflect the long-term real rates of return experienced in the respective markets.

 
                                                  30 June   30 June   31 Dec 
                                                     2012      2011     2011 
                                                        %         %        % 
 
    Discount rate                                     4.6       5.9      5.4 
    Expected return on plan 
     assets                                           5.1       6.5      5.3 
    Inflation                                         2.9       3.7      3.1 
        Rate of increase in salaries                  N/A       N/A      N/A 
    Rate of increase in pensions 
     in                                               2.9       3.7      3.1 
        payment 
    Rate of increase in pensions 
     in                                               2.9       3.7      3.1 
        deferment 
        Life Expectancy assumptions 
    Male currently aged 45                           24.4      24.3     24.4 
    Female currently aged 45                         26.8      26.7     26.8 
    Male currently aged 65                           22.5      22.4     22.5 
    Female currently aged 65                         24.9      24.8     24.9 
                                                 ========  ========  ======= 
 
 
 
 6   Retirement benefit obligations (continued) 
 
 
 ANALYSIS OF AMOUNT CHARGED TO                30 June 2012   30 June 2011   31 Dec 2011 
  OTHER FINANCE COSTS                               GBP000         GBP000        GBP000 
 
 Expected returns on pension scheme assets             144            168           334 
 Interest on pension scheme liabilities              (184)          (196)         (394) 
                                             -------------  -------------  ------------ 
 
 Net finance charge                                   (40)           (28)          (60) 
                                             =============  =============  ============ 
 
 
 
 ANALYSIS OF AMOUNT RECOGNISED IN                    30 June 2012   30 June 2011   31 Dec 2011 
  OTHER COMPREHENSIVE INCOME                               GBP000         GBP000        GBP000 
 
 Actual return less expected return on pension 
  scheme assets                                              (15)           (40)         (480) 
 Experience losses arising on scheme liabilities                -              -             - 
 Changes in assumptions underlying the present 
  value of the scheme liabilities                         (1,766)             13            88 
                                                    -------------  -------------  ------------ 
 
 Actuarial loss recognised in other comprehensive 
  income                                                  (1,781)           (27)         (392) 
                                                    =============  =============  ============ 
 
 
 
 CHANGES IN THE PRESENT VALUE OF THE DEFINED BENEFIT OBLIGATION    30 June 2012   30 June 2011   31 Dec 2011 
                                                                         GBP000         GBP000        GBP000 
 
 Opening defined benefit obligation                                       6,946          6,956         6,956 
 Interest cost                                                              184            196           394 
 Actuarial loss/(gain)                                                    1,766           (13)          (88) 
 Benefits paid                                                             (59)          (182)         (316) 
                                                                  -------------  -------------  ------------ 
 
 Closing defined benefit obligation                                       8,837          6,957         6,946 
                                                                  =============  =============  ============ 
 
 
 
 CHANGES IN THE FAIR VALUE OF PLAN ASSETS    30 June 2012   30 June 2011   31 Dec 2011 
                                                   GBP000         GBP000        GBP000 
 
 Opening plan assets                                5,330          5,479         5,479 
 Expected return                                      144            168           334 
 Actuarial loss                                      (15)           (40)         (480) 
 Contributions by employer                            265            251           313 
 Benefits paid                                       (59)          (182)         (316) 
                                            -------------  -------------  ------------ 
 
 Closing plan assets                                5,665          5,676         5,330 
                                            =============  =============  ============ 
 
 
 
 
 6   Retirement benefit obligations (continued) 
 
 
                                        30 June 2012   30 June 2011    31 Dec 
                                              GBP000         GBP000      2011 
                                                                       GBP000 
 
 Present value of funded obligations         (8,837)        (6,957)   (6,946) 
 Fair value of plan assets                     5,665          5,676     5,330 
                                       -------------  -------------  -------- 
 
 Deficit                                     (3,172)        (1,281)   (1,616) 
 Related deferred tax asset                      761            346       404 
                                       -------------  -------------  -------- 
 
 Net pension liability                       (2,411)          (935)   (1,212) 
                                       =============  =============  ======== 
 
 
 
 ANALYSIS OF CUMULATIVE AMOUNT RECOGNISED IN OTHER COMPREHENSIVE INCOME        Cumulative      Cumulative   Cumulative 
                                                                             30 June 2012    30 June 2011       31 Dec 
                                                                                   GBP000          GBP000         2011 
                                                                                                                GBP000 
 
 Actual return less expected return on pension scheme assets                         (66)            (91)         (51) 
 Experience gains and losses arising on scheme liabilities                          (910)           (910)        (910) 
 Changes in assumptions underlying the present value of the scheme 
  liabilities                                                                     (1,176)             603          590 
                                                                           --------------  --------------  ----------- 
 
 
 Cumulative actuarial loss recognised in other comprehensive income               (2,152)           (398)        (371) 
                                                                           ==============  ==============  =========== 
 
 

The Group expects to contribute GBP0.34m to its defined benefit plans in this financial year (2011: GBP0.31m).

   7.       Availability of this Interim Announcement 

Copies of this announcement are available on the Company's website, www.instem.com. Copies of the Interim Report will be downloadable from the Company's website and available from the registered office of the Company shortly.

INDEPENDENT REVIEW REPORT TO INSTEM PLC

Introduction

We have been engaged by the Company to review the condensed set of financial statements in the interim financial report for the six months ended 30 June 2012 which comprises the Consolidated Statement of Comprehensive Income, Consolidated Statement of Financial Position, Consolidated Statement of Cash Flows, Consolidated Statement of Changes in Equity and the related notes. We have read the other information contained in the interim financial report and considered whether it contains any apparent misstatements or material inconsistencies with the information in the condensed set of financial statements.

This report is made solely to the Company in accordance with International Standard on Review Engagements (UK and Ireland) 2410 "'Review of Interim Financial Information performed by the Independent Auditor of the Entity" issued by the Auditing Practices Board. Our review work has been undertaken so that we might state to the Company those matters we are required to state to them in an independent review report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone other than the Company, for our review work, for this report, or for the conclusions we have formed.

Directors' Responsibilities

The interim financial report is the responsibility of, and has been approved by, the directors. The directors are responsible for preparing and presenting the interim financial report in accordance with the AIM Rules of the London Stock Exchange.

As disclosed in note 1, the annual financial statements of the Group are prepared in accordance with International Financial Reporting Standards and International Financial Reporting Interpretations Committee pronouncements as adopted by the European Union. The condensed set of financial statements included in this interim financial report has been prepared in accordance with the presentation, recognition and measurement criteria of International Financial Reporting Standards and International Financial Reporting Interpretations Committee pronouncements, as adopted by the European Union.

Our Responsibility

Our responsibility is to express to the Company a conclusion on the condensed set of financial statements in the interim financial report based on our review.

Scope of Review

We conducted our review in accordance with International Standard on Review Engagements (UK and Ireland) 2410, "Review of Interim Financial Information Performed by the Independent Auditor of the Entity" issued by the Auditing Practices Board for use in the United Kingdom. A review of interim financial information consists of making enquiries, primarily of persons responsible for financial and accounting matters, and applying analytical and other review procedures. A review is substantially less in scope than an audit conducted in accordance with International Standards on Auditing (UK and Ireland) and consequently does not enable us to obtain assurance that we would become aware of all significant matters that might be identified in an audit. Accordingly, we do not express an audit opinion.

Conclusion

Based on our review, nothing has come to our attention that causes us to believe that the condensed set of financial statements in the interim financial report for the six months ended 30 June 2012 is not prepared, in all material respects, in accordance with the presentation, recognition and measurement criteria of International Financial Reporting Standards and International Financial Reporting Interpretations Committee pronouncements as adopted by the European Union, and the AIM Rules of the London Stock Exchange.

Baker Tilly UK Audit LLP

Chartered Accountants

3 Hardman Street

Manchester M3 3HF

19 September 2012

This information is provided by RNS

The company news service from the London Stock Exchange

END

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