RNS No 2950b
CAMBRIDGE ANTIBODY TECHNOLOGY GROUP
30th November 1998


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
John Aston

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
CAT Group Employees Trustees Limited

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Appropriation of shares on behalf of Director to Inland Revenue approved Staff
Share Scheme administered by CAT Group Employees Trustees Limited and a
separate grant of options.

7   Number of shares/amount of stock acquired:
400

8   Percentage of issued class:
0.01%

9   Number of shares/amount of stock disposed:


10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
242p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
1627

16  Total percentage holding of issued class following this notification:
0.006%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:
November 27 1998

18  Period during which or date on which exercisable:
November 27 2001 - November 26 2005

19  Total amount paid (if any) for grant of the option:
Nil

20  Description of shares or debentures involved: class, number:
10p ordinary shares

21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:
242p

22  Total number of shares or debentures over which options held following
this notification:
143 964

23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
David Chiswell

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2 

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
  As in 2 and  CAT Group Employees Trustees Limited

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
 Exercise of 375,000 options and transfer of same to Linda Chiswell spouse and
appropriation of shares on behalf of Director to Inland Revenue approved Staff
Share Scheme administered by CAT Group Employees Trustees Limited and a
separate grant of options.

7   Number of shares/amount of stock acquired:
375,400

8   Percentage of issued class:
1.59%

9   Number of shares/amount of stock disposed:
375,000 ( to spouse)

10  Percentage of issued class:
1.59%

11  Class of security:
10p ordinary shares

12  Price per share:
242p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
625,627 (with spouse)

16  Total percentage holding of issued class following this notification:
2.66%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:
November 27 1998

18  Period during which or date on which exercisable:
November 27 2001- November 26 2005

19  Total amount paid (if any) for grant of the option:
Nil

20  Description of shares or debentures involved: class, number:
16,116 10p ordinary shares

21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:
242p

22  Total number of shares or debentures over which options held following
this notification:
166,116

23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
David Glover

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
CAT Group Employees Trustees Limited

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Appropriation of shares on behalf of Director to Inland Revenue approved Staff
Share Scheme administered by CAT Group Employees Trustees Limited and a
separate grant of options.

7   Number of shares/amount of stock acquired:
400

8   Percentage of issued class:
0.001%

9   Number of shares/amount of stock disposed:


10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
242p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
6827

16  Total percentage holding of issued class following this notification:
0.03%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:
November 27 1998

18  Period during which or date on which exercisable:
November 27 2001-November 26 2005

19  Total amount paid (if any) for grant of the option:
Nil

20  Description of shares or debentures involved: class, number:
29,964 10p ordinary shares

21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:
242p

22  Total number of shares or debentures over which options held following
this notification:
119,964

23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Kevin Johnson

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:


4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2 and  CAT Group Employees Trustees Limited

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Exercise of 62,500 options and transfer of 31,200 to Sue Johnson spouse and
appropriation of shares on behalf of Director to Inland Revenue approved Staff
Share Scheme administered by CAT Group Employees Trustees Limited and a
separate grant of options.

7   Number of shares/amount of stock acquired:
62,900

8   Percentage of issued class:
0.27%

9   Number of shares/amount of stock disposed:
31,250 transferred to spouse

10  Percentage of issued class:
0.13%

11  Class of security:
10p ordinary shares

12  Price per share:
242p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
63,127 (with spouse)

16  Total percentage holding of issued class following this notification:
0.27%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:
November 27 1998

18  Period during which or date on which exercisable:
November 27 2001-November 26 2005

19  Total amount paid (if any) for grant of the option:
Nil

20  Description of shares or debentures involved: class, number:
 28324 10p ordinary shares

21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:
242p

22  Total number of shares or debentures over which options held following
this notification:
118,324

23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Alistair Cumming

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Grant of 1000 shares in lieu of non executive remuneration of #5000

7   Number of shares/amount of stock acquired:
1000

8   Percentage of issued class:
0.04%

9   Number of shares/amount of stock disposed:


10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
500p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
4100

16  Total percentage holding of issued class following this notification:
0.017%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
James Foght

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
Non-beneficial interest in shares granted to Vector Fund Management in lieu of
Director's non executive remuneration

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
Vector Fund Management

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Grant of 1000 shares to Vector Fund Management in lieu of non executive
remuneration of #5000

7   Number of shares/amount of stock acquired:
1000

8   Percentage of issued class:
0.04%

9   Number of shares/amount of stock disposed:


10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
500p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
Nil

16  Total percentage holding of issued class following this notification:


If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Peter Garland

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
Non beneficial interest in holding of Institute of Cancer Research of 2000
shares granted to Institute in lieu of Director's non executive remuneration

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
Institute of Cancer Research

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
2000 shares granted to Institute of Cancer Research in lieu of Director's non
executive remuneration of #10,000

7   Number of shares/amount of stock acquired:
2000

8   Percentage of issued class:
0.08%

9   Number of shares/amount of stock disposed:


10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
500p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
78,752

16  Total percentage holding of issued class following this notification:
0.34%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary

Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Sir Aaron Klug

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Grant of 1000 shares in lieu of non executive remuneration of #5000

7   Number of shares/amount of stock acquired:
1000

8   Percentage of issued class:
0.04%

9   Number of shares/amount of stock disposed:


10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
500p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
1500

16  Total percentage holding of issued class following this notification:
0.006%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary



Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
John Stocker

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Grant of 1000 shares in lieu of non executive remuneration of #5000

7   Number of shares/amount of stock acquired:
1000

8   Percentage of issued class:
0.04%

9   Number of shares/amount of stock disposed:


10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
500p

13  Date of transaction:
November 27 1998

14  Date company informed:
November 27 1998

15  Total holding following this notification:
1000

16  Total percentage holding of issued class following this notification:
0.04%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary


END

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