FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Dentzer James E
2. Issuer Name and Ticker or Trading Symbol

CURIS INC [ CRIS ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
President & CEO
(Last)          (First)          (Middle)

C/O CURIS, INC., 128 SPRING STREET BUILDING C SUITE 500
3. Date of Earliest Transaction (MM/DD/YYYY)

1/27/2022
(Street)

LEXINGTON, MA 02421
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 1/27/2022  S(1)  2406 D$3.18 67971 D  
Common Stock 1/31/2022  S(2)  3094 D$3.07 64877 D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee stock option (right to buy) $3.09 1/29/2022  A   825000     (3)1/28/2032 Common stock 825000 $0.00 825000 D  

Explanation of Responses:
(1) Shares were sold pursuant to a "sell to cover" arrangement to satisfy minimum statutory tax withholding obligations related to a vesting of a service-based restricted stock award granted on January 22, 2018.
(2) This transaction was effected pursuant to Rule 10b5-1 trading plans to cover tax obligations.
(3) The option grant described in this Form 4 filing vests as to 25% of the original shares on January 29, 2023 and as to an additional 6.25% of the original shares each successive quarter and until January 29, 2026.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Dentzer James E
C/O CURIS, INC.
128 SPRING STREET BUILDING C SUITE 500
LEXINGTON, MA 02421
X
President & CEO

Signatures
William Steinkrauss, attorney-in-fact1/31/2022
**Signature of Reporting PersonDate

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